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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

La Serena and related destinations

Elegant colonial architecture frames La Serena's Plaza de Armas, where you can visit the 19th-century cathedral and nearby archaeological museum. Spend evenings at Avenida del Mar beaches, then take day trips to Elqui Valley observatories or penguin colonies at Humboldt Penguin National Reserve.

Lighthouse at La Serena, Chile

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Find out more about La Serena

There's nothing wrong with enjoying the finer things in life. Pamper yourself on your upcoming getaway. There's no reason to delay a getaway to La Serena any longer. You'll join the multitudes of vacationers who have made La Serena so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Our 5-star hotels in La Serena are the perfect places to relax in during your next chunk of time off.

Get a Great Deal on 5-Star Hotels in La Serena

You'll have a wonderful time at one of these 5-star hotels. Top-notch customer care, granite-tiled bathrooms, and deeply relaxing spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What kind of amenities will make your stay a wonderful one? 24-hour room service, so you can order that Turkish coffee in the wee hours of the morning? A mud wrap treatment that will leave you feeling like a million bucks? Butler services? Whatever it is your heart desires, you're bound to find it here. Want to see for yourself? Explore our listings and pick the perfect accommodation for your needs.

Yearning for experiences outside your hotel room? We hear you. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in La Serena are the perfect place to rest up after a busy day.

Make Your Escape

The results are in, and La Serena 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Expedia can help you land a great deal on accommodation. It's time to plan your next great escape. Opt for one of our La Serena 5-star hotels today and soothe yourself in the lap of luxury tomorrow.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in La Serena?
How much you pay for a 5-star hotel in La Serena depends on factors like when you plan to travel and the length of your stay. An insider tip for bagging an awesome deal? Use our pricing filters to compare the available accommodations for your selected dates.

  • Search for the lowest price per night from $120

What makes a hotel 5 stars in La Serena?
Exemplary guest service is the foundation of every 5-star hotel in La Serena. From the minute you step through the door, staff attend to your every need, whether arranging customized tours or providing a turn-down service. In addition, hotels must feature top-rate amenities to meet the standard for a 5-star rating. These can include deluxe baths, on-site spa facilities, pools, fine dining kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in La Serena?
Use our filter tool to find an upscale escape in La Serena where most of what you need is included in the price. After your initial search, narrow down your results for accommodations that have a 5-star rating and are listed as "All inclusive." The main thing on the agenda at these stays? Pure indulgence and relaxation.

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