$622 Cheap Flights from Madrid (MAD) to Santiago (STI)

View $622 flight on Sat, Feb 21, 2026Opens in a new window

Popular airlines from Adolfo Suarez Madrid-Barajas Airport (MAD) to Cibao Intl. Airport (STI)

Cheap Flights from Madrid to Santiago (MAD-STI)

Prices were available within the past 7 days and start at $622 for one-way flights and $578 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

JetBlue Airways
Wed, Apr 29 - Mon, May 11
MAD
Madrid
STI
Santiago de los Caballeros
$578 Roundtrip, found 1 day ago
$578
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Wed, Apr 29 from Madrid to Santiago de los Caballeros, returning Mon, May 11, priced at $578 found 1 day ago
JetBlue Airways
Wed, Apr 29 - Wed, May 13
MAD
Madrid
STI
Santiago de los Caballeros
$607 Roundtrip, found 1 day ago
$607
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Wed, Apr 29 from Madrid to Santiago de los Caballeros, returning Wed, May 13, priced at $607 found 1 day ago
JetBlue Airways
Wed, Apr 29 - Sun, May 17
MAD
Madrid
STI
Santiago de los Caballeros
$637 Roundtrip, found 1 day ago
$637
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Wed, Apr 29 from Madrid to Santiago de los Caballeros, returning Sun, May 17, priced at $637 found 1 day ago
JetBlue Airways
Thu, Apr 30 - Wed, May 13
MAD
Madrid
STI
Santiago de los Caballeros
$666 Roundtrip, found 1 day ago
$666
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Thu, Apr 30 from Madrid to Santiago de los Caballeros, returning Wed, May 13, priced at $666 found 1 day ago
JetBlue Airways
Wed, Apr 29 - Thu, May 14
MAD
Madrid
STI
Santiago de los Caballeros
$683 Roundtrip, found 1 day ago
$683
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Wed, Apr 29 from Madrid to Santiago de los Caballeros, returning Thu, May 14, priced at $683 found 1 day ago
JetBlue Airways
Thu, Apr 30 - Sun, May 17
MAD
Madrid
STI
Santiago de los Caballeros
$695 Roundtrip, found 1 day ago
$695
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Thu, Apr 30 from Madrid to Santiago de los Caballeros, returning Sun, May 17, priced at $695 found 1 day ago
Delta
Wed, Nov 5 - Wed, Nov 26
MAD
Madrid
STI
Santiago de los Caballeros
$820 Roundtrip, found 5 days ago
$820
Roundtrip
found 5 days ago
Select Delta flight, departing Wed, Nov 5 from Madrid to Santiago de los Caballeros, returning Wed, Nov 26, priced at $820 found 5 days ago
Air Europa
Sat, May 30 - Sat, Jun 13
MAD
Madrid
STI
Santiago de los Caballeros
$933 Roundtrip, found 3 days ago
$933
Roundtrip
found 3 days ago
Select Air Europa flight, departing Sat, May 30 from Madrid to Santiago de los Caballeros, returning Sat, Jun 13, priced at $933 found 3 days ago
United
Thu, Jan 22 - Sat, Feb 7
MAD
Madrid
STI
Santiago de los Caballeros
$948 Roundtrip, found 6 days ago
$948
Roundtrip
found 6 days ago
Select United flight, departing Thu, Jan 22 from Madrid to Santiago de los Caballeros, returning Sat, Feb 7, priced at $948 found 6 days ago
American Airlines
Thu, Mar 5 - Sun, Mar 22
MAD
Madrid
STI
Santiago de los Caballeros
$1,073 Roundtrip, found 4 hours ago
$1,073
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Thu, Mar 5 from Madrid to Santiago de los Caballeros, returning Sun, Mar 22, priced at $1,073 found 4 hours ago

Find the cheapest month to fly from Madrid (MAD) to Santiago de los Caballeros (STI)

September is typically the cheapest month to fly

From $642 - $1,550 per traveler.

Alternative airports near Santiago de los Caballeros

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Gregorio Luperon Intl. POP. Cheapest option available. Average driving time to city center is 59 minutes. Flights from $1,028
POP
Gregorio Luperon Intl.
Cheapest
Average driving time to city center59 min
Flights from $1,028

Frequently asked questions

How much does a flight from Adolfo Suarez Madrid-Barajas Airport (MAD) to Cibao Intl. Airport (STI) cost?
Snag a cheap one-way flight from $622 or cheap return flight from $578 from Adolfo Suarez Madrid-Barajas Airport (MAD) to Cibao Intl. Airport (STI) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Adolfo Suarez Madrid-Barajas Airport (MAD) to Cibao Intl. Airport (STI)?
April is the least expensive month to fly from MAD to STI. Planning your trip for the off-season is often the key to landing a great deal.
Which airlines fly direct from Adolfo Suarez Madrid-Barajas Airport (MAD) to Cibao Intl. Airport (STI)?
When jetting out of Adolfo Suarez Madrid-Barajas Airport (MAD), you can get on a direct flight to Cibao Intl. Airport (STI) with Air Europa.
What is the cheapest airline that flies from Adolfo Suarez Madrid-Barajas Airport (MAD) to Cibao Intl. Airport (STI)?
To find the cheapest airline flying from MAD to STI, use Expedia's filter tool. Tailor your search based on what's important to you, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Adolfo Suarez Madrid-Barajas Airport (MAD) to Cibao Intl. Airport (STI)?
On average, Adolfo Suarez Madrid-Barajas Airport (MAD) offers 1 nonstop flights to Cibao Intl. Airport (STI) each week. If you're looking for more choice, take advantage of Expedia's filter tool to discover flights with layovers. Squeeze in a visit to another location or simply break up your trip.
What are the most popular departure times for flights from Adolfo Suarez Madrid-Barajas Airport (MAD) to Cibao Intl. Airport (STI)?
More passengers fly between MAD and STI at 4 PM than at any other point in the day. Looking for a quieter experience? Consider flying outside peak hours and there's a chance you'll save on your ticket as well.
What day of the week has the most flights from MAD to STI?
Saturday has the most flights from Adolfo Suarez Madrid-Barajas Airport (MAD) to Cibao Intl. Airport (STI). Consider traveling on this day and you'll have a greater chance of finding a departure that fits your schedule.
What is the earliest flight from Adolfo Suarez Madrid-Barajas Airport (MAD) to Cibao Intl. Airport (STI)?
Adolfo Suarez Madrid-Barajas Airport (MAD)'s earliest flight to Cibao Intl. Airport (STI) is at approximately 4:55PM UTC+1. With a total flight time of 8h 40m, you'll touch down at around 8:35PM UTC-4.
How long does it take to fly from Adolfo Suarez Madrid-Barajas Airport (MAD) to Cibao Intl. Airport (STI)?
Flights from MAD to STI have an average travel time of 8 hours and 40 minutes. The distance between these two airports is 4,200 mi.
What airline has the least delays from MAD to STI?
With 88% of journeys usually arriving as scheduled, Air Europa has the best on-time performance for nonstop flights from Adolfo Suarez Madrid-Barajas Airport (MAD) to Cibao Intl. Airport (STI). To monitor your flight status and get notified if anything changes, head to the Expedia App.
What is the best time to fly from Adolfo Suarez Madrid-Barajas Airport (MAD) to Cibao Intl. Airport (STI)?
To avoid possible delays on the Adolfo Suarez Madrid-Barajas Airport (MAD) to Cibao Intl. Airport (STI) route, aim to travel before 3 PM. Later flights are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Santiago de los Caballeros from Adolfo Suarez Madrid-Barajas Airport (MAD)?
If you're boarding a direct flight from Adolfo Suarez Madrid-Barajas Airport (MAD) to Santiago de los Caballeros, Cibao Intl. Airport (STI) is the only airport you can touch down at.
Is it cheaper to buy a plane ticket from Adolfo Suarez Madrid-Barajas Airport (MAD) to Cibao Intl. Airport (STI) last-minute?
Booking your plane ticket from MAD to STI right before your journey is usually more expensive. However, if you're flexible with your itinerary, you could grab a cheap last-minute fare.
Is it cheaper to book a MAD to STI flight and hotel package?
Booking a MAD to STI flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip in one place. Choose from our wide range of hotels and then add activities, flights and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Adolfo Suarez Madrid-Barajas Airport (MAD) to Cibao Intl. Airport (STI)?
In most cases, you can reschedule or cancel your MAD to STI flight. However, additional fees may apply, especially if you made your booking more than 24 hours ago. Double-check your itinerary for the airline's policies and fees on flight changes, or if you'd like more details, go to our Customer Service portal.

Travel information

Origin airport
Adolfo Suárez Madrid-Barajas
Destination airport
Cibao Intl.
Airlines serving
Air Europa, American Airlines, Delta, United
Roundtrip price
$578
Distance
4165 mi
Average flight time
8 hours 40 mins

Book with confidence

Madrid to Santiago Flights

The cheapest times to fly from Madrid to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Madrid to Santiago are during the month of April. You can find some of the cheapest flights from Madrid to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Madrid to Santiago

Sunday is one of the best days to book for cheap flights from Madrid to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Madrid to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Madrid to Santiago in 2025. You can also book with separate airlines for your outbound and return journeys, from $622 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Madrid to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Madrid to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Madrid to Santiago Flights

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*Available to One Key members.