$359 Cheap Flights from Manaus (MAO) to Santo Domingo (SDQ)

View $359 flight on Fri, Jan 2, 2026Opens in a new window

Popular airlines from Manaus (MAO-Eduardo Gomes Intl.) to Las Americas Intl. Airport (SDQ)

Cheap Flights from Manaus to Santo Domingo (MAO-SDQ)

Prices were available within the past 7 days and start at $359 for one-way flights and $642 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Fri, Jan 2 - Mon, Jan 12
MAO
Manaus
SDQ
Santo Domingo
$642 Roundtrip, found 16 hours ago
$642
Roundtrip
found 16 hours ago
Select Copa flight, departing Fri, Jan 2 from Manaus to Santo Domingo, returning Mon, Jan 12, priced at $642 found 16 hours ago
Copa
Fri, Dec 19 - Sat, Jan 10
MAO
Manaus
SDQ
Santo Domingo
$677 Roundtrip, found 8 hours ago
$677
Roundtrip
found 8 hours ago
Select Copa flight, departing Fri, Dec 19 from Manaus to Santo Domingo, returning Sat, Jan 10, priced at $677 found 8 hours ago
Copa
Fri, Jan 2 - Mon, Jan 12
MAO
Manaus
SDQ
Santo Domingo
$712 Roundtrip, found 16 hours ago
$712
Roundtrip
found 16 hours ago
Select Copa flight, departing Fri, Jan 2 from Manaus to Santo Domingo, returning Mon, Jan 12, priced at $712 found 16 hours ago
avianca
Tue, Dec 23 - Tue, Dec 30
MAO
Manaus
SDQ
Santo Domingo
$718 Roundtrip, found 16 hours ago
$718
Roundtrip
found 16 hours ago
Select avianca flight, departing Tue, Dec 23 from Manaus to Santo Domingo, returning Tue, Dec 30, priced at $718 found 16 hours ago
Copa
Wed, Dec 24 - Tue, Dec 30
MAO
Manaus
SDQ
Santo Domingo
$719 Roundtrip, found 16 hours ago
$719
Roundtrip
found 16 hours ago
Select Copa flight, departing Wed, Dec 24 from Manaus to Santo Domingo, returning Tue, Dec 30, priced at $719 found 16 hours ago
Copa
Wed, Dec 31 - Tue, Jan 13
MAO
Manaus
SDQ
Santo Domingo
$725 Roundtrip, found 16 hours ago
$725
Roundtrip
found 16 hours ago
Select Copa flight, departing Wed, Dec 31 from Manaus to Santo Domingo, returning Tue, Jan 13, priced at $725 found 16 hours ago
avianca
Mon, Dec 29 - Tue, Dec 30
MAO
Manaus
SDQ
Santo Domingo
$743 Roundtrip, found 16 hours ago
$743
Roundtrip
found 16 hours ago
Select avianca flight, departing Mon, Dec 29 from Manaus to Santo Domingo, returning Tue, Dec 30, priced at $743 found 16 hours ago
avianca
Thu, Jan 1 - Tue, Jan 13
MAO
Manaus
SDQ
Santo Domingo
$753 Roundtrip, found 16 hours ago
$753
Roundtrip
found 16 hours ago
Select avianca flight, departing Thu, Jan 1 from Manaus to Santo Domingo, returning Tue, Jan 13, priced at $753 found 16 hours ago
Copa
Sun, Jan 4 - Tue, Jan 13
MAO
Manaus
SDQ
Santo Domingo
$754 Roundtrip, found 16 hours ago
$754
Roundtrip
found 16 hours ago
Select Copa flight, departing Sun, Jan 4 from Manaus to Santo Domingo, returning Tue, Jan 13, priced at $754 found 16 hours ago
Copa
Fri, Jan 2 - Tue, Jan 13
MAO
Manaus
SDQ
Santo Domingo
$760 Roundtrip, found 16 hours ago
$760
Roundtrip
found 16 hours ago
Select Copa flight, departing Fri, Jan 2 from Manaus to Santo Domingo, returning Tue, Jan 13, priced at $760 found 16 hours ago

Frequently asked questions

How much does a flight from Eduardo Gomes Intl. Airport (MAO) to Las Americas Intl. Airport (SDQ) cost?
Lock in a cheap one-way flight from $359 or cheap return flight from $642 from Eduardo Gomes Intl. Airport (MAO) to Las Americas Intl. Airport (SDQ) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Eduardo Gomes Intl. Airport (MAO) to Las Americas Intl. Airport (SDQ)?
January is the most affordable month to fly from MAO to SDQ. Planning your trip for the off-season is often the key to better flight prices.
What is the cheapest airline that flies from Eduardo Gomes Intl. Airport (MAO) to Las Americas Intl. Airport (SDQ)?
Expedia's filter tool lets you easily compare airlines, flight times and fares all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest MAO to SDQ flight.
How many flights per day from Eduardo Gomes Intl. Airport (MAO) to Las Americas Intl. Airport (SDQ)?
Direct flights from Eduardo Gomes Intl. Airport (MAO) to Las Americas Intl. Airport (SDQ) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your dates and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MAO to SDQ?
Friday is generally the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can change based on a number of factors, such as the season and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Eduardo Gomes Intl. Airport (MAO) to Las Americas Intl. Airport (SDQ)?
To arrive at Las Americas Intl. Airport (SDQ) without delays, choose a flight that leaves Eduardo Gomes Intl. Airport (MAO) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Eduardo Gomes Intl. Airport (MAO) to Las Americas Intl. Airport (SDQ) last-minute?
Last-minute fares from MAO to SDQ are usually more expensive. For the lowest prices, start searching for flights early. That being said, if you're flexible with your travel plans, it's possible to find a cheap fare right before your journey.
Is it cheaper to book a MAO to SDQ flight and hotel package?
Opting for a MAO to SDQ flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Choose from our wide range of accommodations and then add activities, flights and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Eduardo Gomes Intl. Airport (MAO) to Las Americas Intl. Airport (SDQ)?
You can usually reschedule or cancel your MAO to SDQ flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Travel information

Origin airport
Eduardo Gomes Intl.
Destination airport
Las Americas Intl.
Airlines serving
Copa, avianca
Roundtrip price
$641
Distance
1621 mi

Book with confidence

Book with confidence

Manaus to Santo Domingo Flights

The cheapest times to fly from Manaus to Santo Domingo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Manaus to Santo Domingo are during the month of January. You can find some of the cheapest flights from Manaus to Santo Domingo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Manaus to Santo Domingo

Sunday is one of the best days to book for cheap flights from Manaus to Santo Domingo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Manaus to Santo Domingo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Manaus to Santo Domingo in 2025. You can also book with separate airlines for your outbound and return journeys, from $359 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Manaus to Santo Domingo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Manaus to Santo Domingo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Manaus to Santo Domingo Flights

Explore a world of travel with Expedia

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*Available to One Key members.