$244 Cheap Flights from Medellín (MDE) to São Paulo (GRU)

View $244 flight on Sun, Feb 8, 2026Opens in a new window

Popular airlines from Jose Maria Cordova Intl. Airport (MDE) to São Paulo/Guarulhos Intl. Airport

Cheap Flights from Medellín to São Paulo (MDE-GRU)

Prices were available within the past 7 days and start at $244 for one-way flights and $370 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Wed, Nov 5 - Sat, Nov 8
MDE
Medellin
GRU
Sao Paulo
$370 Roundtrip, found 2 days ago
$370
Roundtrip
found 2 days ago
Select Copa flight, departing Wed, Nov 5 from Medellin to Sao Paulo, returning Sat, Nov 8, priced at $370 found 2 days ago
Copa
Wed, Nov 5 - Sat, Nov 8
MDE
Medellin
GRU
Sao Paulo
$387 Roundtrip, found 2 days ago
$387
Roundtrip
found 2 days ago
Select Copa flight, departing Wed, Nov 5 from Medellin to Sao Paulo, returning Sat, Nov 8, priced at $387 found 2 days ago
LATAM Airlines Group
Mon, Feb 9 - Wed, Feb 18
MDE
Medellin
GRU
Sao Paulo
$390 Roundtrip, found 3 days ago
$390
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Mon, Feb 9 from Medellin to Sao Paulo, returning Wed, Feb 18, priced at $390 found 3 days ago
Copa
Wed, Nov 5 - Sat, Nov 8
MDE
Medellin
GRU
Sao Paulo
$394 Roundtrip, found 2 days ago
$394
Roundtrip
found 2 days ago
Select Copa flight, departing Wed, Nov 5 from Medellin to Sao Paulo, returning Sat, Nov 8, priced at $394 found 2 days ago
LATAM Airlines Group
Tue, Nov 18 - Mon, Dec 1
MDE
Medellin
GRU
Sao Paulo
$402 Roundtrip, found 2 days ago
$402
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Tue, Nov 18 from Medellin to Sao Paulo, returning Mon, Dec 1, priced at $402 found 2 days ago
Copa
Mon, Nov 17 - Mon, Dec 1
MDE
Medellin
GRU
Sao Paulo
$408 Roundtrip, found 2 days ago
$408
Roundtrip
found 2 days ago
Select Copa flight, departing Mon, Nov 17 from Medellin to Sao Paulo, returning Mon, Dec 1, priced at $408 found 2 days ago
LATAM Airlines Group
Tue, Nov 18 - Sun, Nov 23
MDE
Medellin
GRU
Sao Paulo
$410 Roundtrip, found 6 days ago
$410
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Tue, Nov 18 from Medellin to Sao Paulo, returning Sun, Nov 23, priced at $410 found 6 days ago
Copa
Mon, Nov 17 - Mon, Dec 1
MDE
Medellin
GRU
Sao Paulo
$411 Roundtrip, found 2 days ago
$411
Roundtrip
found 2 days ago
Select Copa flight, departing Mon, Nov 17 from Medellin to Sao Paulo, returning Mon, Dec 1, priced at $411 found 2 days ago
GOL Linhas Aereas S.A.
Mon, Mar 16 - Fri, Mar 27
MDE
Medellin
GRU
Sao Paulo
$423 Roundtrip, found 6 days ago
$423
Roundtrip
found 6 days ago
Select GOL Linhas Aereas S.A. flight, departing Mon, Mar 16 from Medellin to Sao Paulo, returning Fri, Mar 27, priced at $423 found 6 days ago
avianca
Tue, Nov 11 - Mon, Nov 24
MDE
Medellin
GRU
Sao Paulo
$424 Roundtrip, found 2 days ago
$424
Roundtrip
found 2 days ago
Select avianca flight, departing Tue, Nov 11 from Medellin to Sao Paulo, returning Mon, Nov 24, priced at $424 found 2 days ago

Alternative airports near São Paulo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Guarulhos - Governor Andre Franco Montoro Intl. GRU. Cheapest option available. Average driving time to city center is 22 minutes. Flights from $442
GRU
Guarulhos - Governor Andre Franco Montoro Intl.
Cheapest
Average driving time to city center22 min
Flights from $442
Flights from Medellín (MDE) to São Paulo (GRU)
Origin airport
José María Córdova Intl.
Destination airport
Guarulhos - Governor André Franco Montoro Intl.
Airlines serving
Copa, GOL Linhas Aereas S.A., LATAM Airlines Group, avianca
Roundtrip price
$370
Distance
2827 mi

Medellín to São Paulo Flights

The cheapest times to fly from Medellín to São Paulo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Medellín to São Paulo are during the month of November. You can find some of the cheapest flights from Medellín to São Paulo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Medellín to São Paulo

Sunday is one of the best days to book for cheap flights from Medellín to São Paulo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Medellín to São Paulo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Medellín to São Paulo in 2025. You can also book with separate airlines for your outbound and return journeys, from $244 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Medellín to São Paulo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Medellín to São Paulo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Jose Maria Cordova Intl. Airport (MDE) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU) cost?
Secure a cheap one-way flight from $244 or cheap return flight from $370 from Jose Maria Cordova Intl. Airport (MDE) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Jose Maria Cordova Intl. Airport (MDE) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
The cheapest month to fly from MDE to GRU is November, when there's less demand. Off-peak season is usually when better flight deals are available between these airports.
Which airlines fly direct from Jose Maria Cordova Intl. Airport (MDE) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
When departing from Jose Maria Cordova Intl. Airport (MDE), you can board a direct flight to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU) with AVIANCA.
What is the cheapest airline that flies from Jose Maria Cordova Intl. Airport (MDE) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
To find the cheapest airline flying from MDE to GRU, use Expedia's filter tool. Tailor your search based on what matters most to you, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from Jose Maria Cordova Intl. Airport (MDE) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
On average, Jose Maria Cordova Intl. Airport (MDE) has 3 direct flights to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU) each week. If you're looking for more options, use Expedia's filters to discover flights with one or two stops. Squeeze in a quick visit to another location or simply break up your trip.
What are the most popular departure times for flights from Jose Maria Cordova Intl. Airport (MDE) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
Flights between MDE and GRU are busiest at 5 PM. If you're after a more relaxed trip and potentially cheaper fares, look for a time when demand is lower.
What day of the week has the most flights from MDE to GRU?
Thursday has the most flights from Jose Maria Cordova Intl. Airport (MDE) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU). Consider jetting off on this day and you'll have the best chance of finding a departure that fits your schedule.
What is the earliest flight from Jose Maria Cordova Intl. Airport (MDE) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
Jose Maria Cordova Intl. Airport (MDE)'s earliest flight to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU) takes off at approximately 5:45PM UTC-5. With a total flight time of 6h 10m, you'll land at around 1:55AM UTC-3.
How long does it take to fly from Jose Maria Cordova Intl. Airport (MDE) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
Flights from MDE to GRU have an average travel time of 6 hours and 10 minutes. The distance between the two is 2,800 mi.
What is the best time to fly from Jose Maria Cordova Intl. Airport (MDE) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
To touch down at Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU) on time, opt for a flight that takes off from Jose Maria Cordova Intl. Airport (MDE) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Sao Paulo from Jose Maria Cordova Intl. Airport (MDE)?
If you've booked a direct flight from Jose Maria Cordova Intl. Airport (MDE) to Sao Paulo, Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU) is the only airport you can land at.
Is it cheaper to buy a plane ticket from Jose Maria Cordova Intl. Airport (MDE) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU) last-minute?
Booking your flight from MDE to GRU right before your trip is typically more expensive. However, if there's some wiggle room with your schedule, you could grab a cheap last-minute fare.
Is it cheaper to book a MDE to GRU flight and hotel package?
You'll typically save money by securing a MDE to GRU flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one place. Once you've selected your preferred flights and accommodations, consider other add-ons like tours, activities and car rentals.
Can I cancel or change the date of my flight from Jose Maria Cordova Intl. Airport (MDE) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
Typically, you're able to cancel or reschedule your MDE to GRU flight. However, there may be additional charges, especially if you booked over 24 hours ago. Double-check your itinerary for the airline's guidelines and fees on flight changes, or if you'd like more details, go to our Customer Service portal.

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*Available to One Key members.