$251 Cheap Flights from Medellín (MDE) to Manaus (MAO)

View $251 flight on Tue, Nov 18, 2025Opens in a new window

Popular airlines from Jose Maria Cordova Intl. Airport (MDE) to Manaus (MAO-Eduardo Gomes Intl.)

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Cheap Flights from Medellín to Manaus (MDE-MAO)

Prices were available within the past 7 days and start at $251 for one-way flights and $458 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Tue, Nov 18 - Sat, Nov 22
MDE
Medellin
MAO
Manaus
$458 Roundtrip, found 5 days ago
$458
Roundtrip
found 5 days ago
Select Copa flight, departing Tue, Nov 18 from Medellin to Manaus, returning Sat, Nov 22, priced at $458 found 5 days ago
avianca
Wed, Nov 19 - Tue, Nov 25
MDE
Medellin
MAO
Manaus
$463 Roundtrip, found 5 days ago
$463
Roundtrip
found 5 days ago
Select avianca flight, departing Wed, Nov 19 from Medellin to Manaus, returning Tue, Nov 25, priced at $463 found 5 days ago
Copa
Sun, Nov 16 - Wed, Nov 19
MDE
Medellin
MAO
Manaus
$489 Roundtrip, found 5 days ago
$489
Roundtrip
found 5 days ago
Select Copa flight, departing Sun, Nov 16 from Medellin to Manaus, returning Wed, Nov 19, priced at $489 found 5 days ago
Copa
Tue, Nov 18 - Fri, Nov 21
MDE
Medellin
MAO
Manaus
$507 Roundtrip, found 5 days ago
$507
Roundtrip
found 5 days ago
Select Copa flight, departing Tue, Nov 18 from Medellin to Manaus, returning Fri, Nov 21, priced at $507 found 5 days ago
avianca
Wed, Nov 19 - Mon, Nov 24
MDE
Medellin
MAO
Manaus
$508 Roundtrip, found 5 days ago
$508
Roundtrip
found 5 days ago
Select avianca flight, departing Wed, Nov 19 from Medellin to Manaus, returning Mon, Nov 24, priced at $508 found 5 days ago
Copa
Mon, Jan 19 - Tue, Jan 27
MDE
Medellin
MAO
Manaus
$524 Roundtrip, found 14 hours ago
$524
Roundtrip
found 14 hours ago
Select Copa flight, departing Mon, Jan 19 from Medellin to Manaus, returning Tue, Jan 27, priced at $524 found 14 hours ago
avianca
Mon, Nov 17 - Thu, Nov 20
MDE
Medellin
MAO
Manaus
$531 Roundtrip, found 5 days ago
$531
Roundtrip
found 5 days ago
Select avianca flight, departing Mon, Nov 17 from Medellin to Manaus, returning Thu, Nov 20, priced at $531 found 5 days ago
avianca
Wed, Nov 19 - Sat, Nov 22
MDE
Medellin
MAO
Manaus
$537 Roundtrip, found 5 days ago
$537
Roundtrip
found 5 days ago
Select avianca flight, departing Wed, Nov 19 from Medellin to Manaus, returning Sat, Nov 22, priced at $537 found 5 days ago
GOL Linhas Aereas S.A.
Sun, Nov 2 - Sun, Nov 9
MDE
Medellin
MAO
Manaus
$554 Roundtrip, found 1 day ago
$554
Roundtrip
found 1 day ago
Select GOL Linhas Aereas S.A. flight, departing Sun, Nov 2 from Medellin to Manaus, returning Sun, Nov 9, priced at $554 found 1 day ago
LATAM Airlines Group
Fri, Jan 23 - Sat, Jan 24
MDE
Medellin
MAO
Manaus
$2,592 Roundtrip, found 14 hours ago
$2,592
Roundtrip
found 14 hours ago
Select LATAM Airlines Group flight, departing Fri, Jan 23 from Medellin to Manaus, returning Sat, Jan 24, priced at $2,592 found 14 hours ago

Frequently asked questions

How much does a flight from Jose Maria Cordova Intl. Airport (MDE) to Eduardo Gomes Intl. Airport (MAO) cost?
Grab a cheap one-way flight from $251 or cheap return flight from $458 from Jose Maria Cordova Intl. Airport (MDE) to Eduardo Gomes Intl. Airport (MAO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Jose Maria Cordova Intl. Airport (MDE) to Eduardo Gomes Intl. Airport (MAO)?
Flying in November can help you save, as it's the cheapest month for flights between MDE and MAO. You'll typically find the lowest fares during the off-season.
What is the cheapest airline that flies from Jose Maria Cordova Intl. Airport (MDE) to Eduardo Gomes Intl. Airport (MAO)?
To find the cheapest airline flying from MDE to MAO, use Expedia's filter tool. Customize your search based on your travel needs, such as preferred carriers and number of stops. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Jose Maria Cordova Intl. Airport (MDE) to Eduardo Gomes Intl. Airport (MAO)?
There are no daily direct flights from Jose Maria Cordova Intl. Airport (MDE) to Eduardo Gomes Intl. Airport (MAO). But you can opt for flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be on your way before you know it.
What day of the week has the most flights from MDE to MAO?
Generally you'll find the greatest selection of flight options on a Friday. Tuesdays tend to be the quietest.* However, this can vary depending on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Jose Maria Cordova Intl. Airport (MDE) to Eduardo Gomes Intl. Airport (MAO)?
To avoid potential delays on the Jose Maria Cordova Intl. Airport (MDE) to Eduardo Gomes Intl. Airport (MAO) route, aim to travel before 3 PM. Later departures are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Jose Maria Cordova Intl. Airport (MDE) to Eduardo Gomes Intl. Airport (MAO) last-minute?
Booking your plane ticket from MDE to MAO right before your getaway is generally more expensive. But if you're flexible with your travel times and dates, you could snag a cheap last-minute fare.
Is it cheaper to book a MDE to MAO flight and hotel package?
Opting for a MDE to MAO flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Pick from our extensive range of accommodations and then add activities, car rentals and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Jose Maria Cordova Intl. Airport (MDE) to Eduardo Gomes Intl. Airport (MAO)?
If you booked your MDE to MAO flight in the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for more details.

Travel information

Origin airport
José María Córdova Intl.
Destination airport
Eduardo Gomes Intl.
Airlines serving
Copa, GOL Linhas Aereas S.A., avianca
Roundtrip price
$458
Distance
1237 mi

Book with confidence

Medellín to Manaus Flights

The cheapest times to fly from Medellín to Manaus

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Medellín to Manaus are during the month of November. You can find some of the cheapest flights from Medellín to Manaus with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Medellín to Manaus

Sunday is one of the best days to book for cheap flights from Medellín to Manaus: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Medellín to Manaus

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Medellín to Manaus in 2025. You can also book with separate airlines for your outbound and return journeys, from $251 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Medellín to Manaus flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Medellín to Manaus airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Medellín to Manaus Flights

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*Available to One Key members.