$472 Cheap Flights from Medellín (MDE) to McAllen (MFE)

View $472 flight on Fri, Oct 31, 2025Opens in a new window

Popular airlines from Jose Maria Cordova Intl. Airport (MDE) to Miller Intl. Airport (MFE)

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Cheap Flights from Medellín to McAllen (MDE-MFE)

Prices were available within the past 7 days and start at $472 for one-way flights and $560 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, Jan 23 - Mon, Jan 26
MDE
Medellin
MFE
McAllen
$560 Roundtrip, found 6 days ago
$560
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Jan 23 from Medellin to McAllen, returning Mon, Jan 26, priced at $560 found 6 days ago
American Airlines
Fri, Jan 23 - Mon, Jan 26
MDE
Medellin
MFE
McAllen
$577 Roundtrip, found 6 days ago
$577
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Jan 23 from Medellin to McAllen, returning Mon, Jan 26, priced at $577 found 6 days ago
American Airlines
Fri, Jan 23 - Mon, Jan 26
MDE
Medellin
MFE
McAllen
$598 Roundtrip, found 6 days ago
$598
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Jan 23 from Medellin to McAllen, returning Mon, Jan 26, priced at $598 found 6 days ago
American Airlines
Mon, Nov 10 - Mon, Nov 17
MDE
Medellin
MFE
McAllen
$614 Roundtrip, found 2 days ago
$614
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Nov 10 from Medellin to McAllen, returning Mon, Nov 17, priced at $614 found 2 days ago
United
Fri, Nov 7 - Tue, Nov 18
MDE
Medellin
MFE
McAllen
$621 Roundtrip, found 2 days ago
$621
Roundtrip
found 2 days ago
Select United flight, departing Fri, Nov 7 from Medellin to McAllen, returning Tue, Nov 18, priced at $621 found 2 days ago
United
Fri, Nov 7 - Fri, Nov 14
MDE
Medellin
MFE
McAllen
$632 Roundtrip, found 2 days ago
$632
Roundtrip
found 2 days ago
Select United flight, departing Fri, Nov 7 from Medellin to McAllen, returning Fri, Nov 14, priced at $632 found 2 days ago
American Airlines
Mon, Nov 10 - Mon, Nov 17
MDE
Medellin
MFE
McAllen
$633 Roundtrip, found 2 days ago
$633
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Nov 10 from Medellin to McAllen, returning Mon, Nov 17, priced at $633 found 2 days ago
United
Fri, Nov 7 - Sun, Nov 16
MDE
Medellin
MFE
McAllen
$635 Roundtrip, found 2 days ago
$635
Roundtrip
found 2 days ago
Select United flight, departing Fri, Nov 7 from Medellin to McAllen, returning Sun, Nov 16, priced at $635 found 2 days ago
United
Sat, Nov 8 - Fri, Nov 14
MDE
Medellin
MFE
McAllen
$643 Roundtrip, found 2 days ago
$643
Roundtrip
found 2 days ago
Select United flight, departing Sat, Nov 8 from Medellin to McAllen, returning Fri, Nov 14, priced at $643 found 2 days ago
American Airlines
Fri, Jan 23 - Mon, Jan 26
MDE
Medellin
MFE
McAllen
$653 Roundtrip, found 6 days ago
$653
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Jan 23 from Medellin to McAllen, returning Mon, Jan 26, priced at $653 found 6 days ago

Frequently asked questions

How much does a flight from Jose Maria Cordova Intl. Airport (MDE) to Miller Intl. Airport (MFE) cost?
Lock in a cheap one-way flight from $472 or cheap return flight from $560 from Jose Maria Cordova Intl. Airport (MDE) to Miller Intl. Airport (MFE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Jose Maria Cordova Intl. Airport (MDE) to Miller Intl. Airport (MFE)?
January is the least expensive month to fly from MDE to MFE. Traveling during an off-peak travel window is often the key to finding better fares.
What is the cheapest airline that flies from Jose Maria Cordova Intl. Airport (MDE) to Miller Intl. Airport (MFE)?
Expedia's filter tool lets you easily compare different airlines, travel time and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest MDE to MFE flight.
How many flights per day from Jose Maria Cordova Intl. Airport (MDE) to Miller Intl. Airport (MFE)?
Direct flights from Jose Maria Cordova Intl. Airport (MDE) to Miller Intl. Airport (MFE) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MDE to MFE?
Typically you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* But this can vary based on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Jose Maria Cordova Intl. Airport (MDE) to Miller Intl. Airport (MFE)?
To avoid possible delays on the Jose Maria Cordova Intl. Airport (MDE) to Miller Intl. Airport (MFE) route, travel before 3 PM. Later departures are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Jose Maria Cordova Intl. Airport (MDE) to Miller Intl. Airport (MFE) last-minute?
Booking your plane ticket from MDE to MFE right before your journey is generally more expensive. But if you're flexible with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a MDE to MFE flight and hotel package?
You'll generally save money by booking a MDE to MFE flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one convenient place. After choosing your preferred flights and accommodations, consider adding extras such as car rentals, activities and tours.
Can I cancel or change the date of my flight from Jose Maria Cordova Intl. Airport (MDE) to Miller Intl. Airport (MFE)?
If you booked your MDE to MFE flight within the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the type of fare you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal if you'd like more information.

Travel information

Origin airport
José María Córdova Intl.
Destination airport
Miller Intl.
Roundtrip price
$559
Distance
2042 mi

Book with confidence

Medellín to McAllen Flights

The cheapest times to fly from Medellín to McAllen

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Medellín to McAllen are during the month of January. You can find some of the cheapest flights from Medellín to McAllen with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Medellín to McAllen

Sunday is one of the best days to book for cheap flights from Medellín to McAllen: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Medellín to McAllen

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Medellín to McAllen in 2025. You can also book with separate airlines for your outbound and return journeys, from $472 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Medellín to McAllen flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Medellín to McAllen airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Medellín to McAllen Flights

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*Available to One Key members.