$435 Cheap Flights from Mendoza (MDZ) to Panama City (PTY)

View $435 flight on Tue, Nov 18, 2025Opens in a new window

Popular airlines from Mendoza (MDZ-Governor Francisco Gabrielli Intl.) to Tocumen Intl. Airport (PTY)

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Cheap Flights from Mendoza to Panama City (MDZ-PTY)

Prices were available within the past 7 days and start at $435 for one-way flights and $780 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aerolineas Argentinas
Wed, Dec 24 - Sun, Jan 4
MDZ
Mendoza
PTY
Panama City
$780 Roundtrip, found 1 day ago
$780
Roundtrip
found 1 day ago
Select Aerolineas Argentinas flight, departing Wed, Dec 24 from Mendoza to Panama City, returning Sun, Jan 4, priced at $780 found 1 day ago
Aerolineas Argentinas
Tue, Dec 16 - Sun, Jan 4
MDZ
Mendoza
PTY
Panama City
$812 Roundtrip, found 1 day ago
$812
Roundtrip
found 1 day ago
Select Aerolineas Argentinas flight, departing Tue, Dec 16 from Mendoza to Panama City, returning Sun, Jan 4, priced at $812 found 1 day ago
Copa
Wed, Dec 24 - Thu, Jan 1
MDZ
Mendoza
PTY
Panama City
$816 Roundtrip, found 13 hours ago
$816
Roundtrip
found 13 hours ago
Select Copa flight, departing Wed, Dec 24 from Mendoza to Panama City, returning Thu, Jan 1, priced at $816 found 13 hours ago
Aerolineas Argentinas
Wed, Dec 17 - Sun, Jan 4
MDZ
Mendoza
PTY
Panama City
$844 Roundtrip, found 1 day ago
$844
Roundtrip
found 1 day ago
Select Aerolineas Argentinas flight, departing Wed, Dec 17 from Mendoza to Panama City, returning Sun, Jan 4, priced at $844 found 1 day ago
Aerolineas Argentinas
Tue, Nov 18 - Sun, Feb 1
MDZ
Mendoza
PTY
Panama City
$876 Roundtrip, found 2 days ago
$876
Roundtrip
found 2 days ago
Select Aerolineas Argentinas flight, departing Tue, Nov 18 from Mendoza to Panama City, returning Sun, Feb 1, priced at $876 found 2 days ago
Copa
Mon, Nov 17 - Fri, Feb 6
MDZ
Mendoza
PTY
Panama City
$905 Roundtrip, found 2 days ago
$905
Roundtrip
found 2 days ago
Select Copa flight, departing Mon, Nov 17 from Mendoza to Panama City, returning Fri, Feb 6, priced at $905 found 2 days ago
Copa
Wed, Dec 24 - Thu, Jan 1
MDZ
Mendoza
PTY
Panama City
$913 Roundtrip, found 13 hours ago
$913
Roundtrip
found 13 hours ago
Select Copa flight, departing Wed, Dec 24 from Mendoza to Panama City, returning Thu, Jan 1, priced at $913 found 13 hours ago
SKY AIRLINE
Mon, Dec 8 - Wed, Dec 24
MDZ
Mendoza
PTY
Panama City
$1,098 Roundtrip, found 1 day ago
$1,098
Roundtrip
found 1 day ago
Select SKY AIRLINE flight, departing Mon, Dec 8 from Mendoza to Panama City, returning Wed, Dec 24, priced at $1,098 found 1 day ago
GOL Linhas Aereas S.A.
Fri, Nov 21 - Wed, Feb 4
MDZ
Mendoza
PTY
Panama City
$1,126 Roundtrip, found 2 days ago
$1,126
Roundtrip
found 2 days ago
Select GOL Linhas Aereas S.A. flight, departing Fri, Nov 21 from Mendoza to Panama City, returning Wed, Feb 4, priced at $1,126 found 2 days ago
American Airlines
Sun, Feb 1 - Fri, Feb 13
MDZ
Mendoza
PTY
Panama City
$2,797 Roundtrip, found 5 days ago
$2,797
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sun, Feb 1 from Mendoza to Panama City, returning Fri, Feb 13, priced at $2,797 found 5 days ago
Flights from Mendoza (MDZ) to Panama City (PTY)
Origin airport
Governor Francisco Gabrielli Intl.
Destination airport
Tocumen Intl.
Airlines serving
Copa
Roundtrip price
$780
Distance
2977 mi
Average flight time
6 hours 56 mins

Mendoza to Panama City Flights

The cheapest times to fly from Mendoza to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mendoza to Panama City are during the month of December. You can find some of the cheapest flights from Mendoza to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Mendoza to Panama City

Sunday is one of the best days to book for cheap flights from Mendoza to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Mendoza to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mendoza to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $435 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mendoza to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mendoza to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Governor Francisco Gabrielli Intl. Airport (MDZ) to Tocumen Intl. Airport (PTY) cost?
Lock in a cheap one-way flight from $435 or cheap return flight from $780 from Governor Francisco Gabrielli Intl. Airport (MDZ) to Tocumen Intl. Airport (PTY) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Governor Francisco Gabrielli Intl. Airport (MDZ) to Tocumen Intl. Airport (PTY)?
Planning your getaway for December is a great way to save, as it's the cheapest month for flights between MDZ and PTY. You'll usually find the lowest prices during the off-season.
Which airlines fly direct from Governor Francisco Gabrielli Intl. Airport (MDZ) to Tocumen Intl. Airport (PTY)?
Board a nonstop flight with Copa Airlines and go straight from Governor Francisco Gabrielli Intl. Airport (MDZ) to Tocumen Intl. Airport (PTY).
What is the cheapest airline that flies from Governor Francisco Gabrielli Intl. Airport (MDZ) to Tocumen Intl. Airport (PTY)?
Expedia's filter tool lets you easily compare airlines, flight times and fares all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest MDZ to PTY flight.
How many flights per day from Governor Francisco Gabrielli Intl. Airport (MDZ) to Tocumen Intl. Airport (PTY)?
On average, Governor Francisco Gabrielli Intl. Airport (MDZ) offers 6 nonstop flights to Tocumen Intl. Airport (PTY) weekly. If you're looking for more choice, use Expedia's filter tool to look for flights with one or two stops. Squeeze in a quick visit to another city or just break up your journey.
What are the most popular departure times for flights from Governor Francisco Gabrielli Intl. Airport (MDZ) to Tocumen Intl. Airport (PTY)?
Flights between MDZ and PTY tend to be busiest at 1 AM. If you're after a less crowded experience and potentially cheaper prices, choose a time outside the usual busy windows.
What day of the week has the most flights from MDZ to PTY?
Fly on a Saturday if you're looking for the best selection of flights from Governor Francisco Gabrielli Intl. Airport (MDZ) to Tocumen Intl. Airport (PTY).
What is the earliest flight from Governor Francisco Gabrielli Intl. Airport (MDZ) to Tocumen Intl. Airport (PTY)?
The first flight of the day jetting off from Governor Francisco Gabrielli Intl. Airport (MDZ) is at around 1:31AM UTC-3. Board this flight and you'll reach Tocumen Intl. Airport (PTY) at approximately 6:09AM UTC-5. The total flight duration is 6h 38m.
How long does it take to fly from Governor Francisco Gabrielli Intl. Airport (MDZ) to Tocumen Intl. Airport (PTY)?
It takes approximately 6 hours and 38 minutes to fly the 3,000 mi from MDZ to PTY.
What airline has the least delays from MDZ to PTY?
With 89% of flights usually arriving on time, Copa Airlines has the best on-time performance for nonstop flights from Governor Francisco Gabrielli Intl. Airport (MDZ) to Tocumen Intl. Airport (PTY). To check your flight status and get notifications about any changes, head to the Expedia App.
What is the best time to fly from Governor Francisco Gabrielli Intl. Airport (MDZ) to Tocumen Intl. Airport (PTY)?
To avoid possible delays on the Governor Francisco Gabrielli Intl. Airport (MDZ) to Tocumen Intl. Airport (PTY) route, fly before 3 PM. Departures after this hour have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Panama City from Governor Francisco Gabrielli Intl. Airport (MDZ)?
Tocumen Intl. Airport (PTY) is the only airport in Panama City with direct flights from Governor Francisco Gabrielli Intl. Airport (MDZ). Explore the available options and discover cheap fares on Expedia.
Is it cheaper to buy a plane ticket from Governor Francisco Gabrielli Intl. Airport (MDZ) to Tocumen Intl. Airport (PTY) last-minute?
Waiting until just before your trip to book a ticket from MDZ to PTY often results in higher prices. While you may come across some last-minute offers, they're not always guaranteed. Allow some flexibility in your schedule for the best chance of getting a bargain.
Is it cheaper to book a MDZ to PTY flight and hotel package?
Compared with arranging flights and hotels separately, booking a MDZ to PTY flight and hotel package with Expedia could lead to significant savings. Better still, having everything in one easy place takes the hassle out of planning your trip. Just secure your flights and select from our wide range of hotels, then personalize your trip with extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Governor Francisco Gabrielli Intl. Airport (MDZ) to Tocumen Intl. Airport (PTY)?
If you booked your MDZ to PTY flight within the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for more information.

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*Available to One Key members.