$294 Cheap Flights from Mendoza (MDZ) to Santa Cruz (VVI)

View $294 flight on Tue, Nov 11, 2025Opens in a new window

Popular airlines from Mendoza (MDZ-Governor Francisco Gabrielli Intl.) to Santa Cruz (VVI-Viru Viru Intl.)

Cheap Flights from Mendoza to Santa Cruz (MDZ-VVI)

Prices were available within the past 7 days and start at $294 for one-way flights and $500 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aerolineas Argentinas
Fri, Dec 5 - Tue, Dec 16
MDZ
Mendoza
VVI
Santa Cruz
$500 Roundtrip, found 1 day ago
$500
Roundtrip
found 1 day ago
Select Aerolineas Argentinas flight, departing Fri, Dec 5 from Mendoza to Santa Cruz, returning Tue, Dec 16, priced at $500 found 1 day ago
LATAM Airlines Group
Sat, Nov 8 - Sun, Nov 23
MDZ
Mendoza
VVI
Santa Cruz
$523 Roundtrip, found 1 hour ago
$523
Roundtrip
found 1 hour ago
Select LATAM Airlines Group flight, departing Sat, Nov 8 from Mendoza to Santa Cruz, returning Sun, Nov 23, priced at $523 found 1 hour ago
Aerolineas Argentinas
Fri, Nov 7 - Tue, Nov 18
MDZ
Mendoza
VVI
Santa Cruz
$528 Roundtrip, found 1 day ago
$528
Roundtrip
found 1 day ago
Select Aerolineas Argentinas flight, departing Fri, Nov 7 from Mendoza to Santa Cruz, returning Tue, Nov 18, priced at $528 found 1 day ago
GOL Linhas Aereas S.A.
Tue, Nov 11 - Thu, Nov 27
MDZ
Mendoza
VVI
Santa Cruz
$551 Roundtrip, found 1 day ago
$551
Roundtrip
found 1 day ago
Select GOL Linhas Aereas S.A. flight, departing Tue, Nov 11 from Mendoza to Santa Cruz, returning Thu, Nov 27, priced at $551 found 1 day ago
Aerolineas Argentinas
Fri, Nov 7 - Sat, Nov 29
MDZ
Mendoza
VVI
Santa Cruz
$553 Roundtrip, found 1 hour ago
$553
Roundtrip
found 1 hour ago
Select Aerolineas Argentinas flight, departing Fri, Nov 7 from Mendoza to Santa Cruz, returning Sat, Nov 29, priced at $553 found 1 hour ago
LATAM Airlines Group
Fri, Oct 24 - Sun, Nov 2
MDZ
Mendoza
VVI
Santa Cruz
$556 Roundtrip, found 2 hours ago
$556
Roundtrip
found 2 hours ago
Select LATAM Airlines Group flight, departing Fri, Oct 24 from Mendoza to Santa Cruz, returning Sun, Nov 2, priced at $556 found 2 hours ago
Aerolineas Argentinas
Fri, Feb 13 - Sat, Feb 28
MDZ
Mendoza
VVI
Santa Cruz
$556 Roundtrip, found 1 day ago
$556
Roundtrip
found 1 day ago
Select Aerolineas Argentinas flight, departing Fri, Feb 13 from Mendoza to Santa Cruz, returning Sat, Feb 28, priced at $556 found 1 day ago
GOL Linhas Aereas S.A.
Tue, Feb 24 - Mon, Mar 9
MDZ
Mendoza
VVI
Santa Cruz
$562 Roundtrip, found 1 day ago
$562
Roundtrip
found 1 day ago
Select GOL Linhas Aereas S.A. flight, departing Tue, Feb 24 from Mendoza to Santa Cruz, returning Mon, Mar 9, priced at $562 found 1 day ago
GOL Linhas Aereas S.A.
Tue, Nov 11 - Wed, Dec 3
MDZ
Mendoza
VVI
Santa Cruz
$573 Roundtrip, found 1 day ago
$573
Roundtrip
found 1 day ago
Select GOL Linhas Aereas S.A. flight, departing Tue, Nov 11 from Mendoza to Santa Cruz, returning Wed, Dec 3, priced at $573 found 1 day ago
Copa
Sat, Nov 8 - Mon, Nov 10
MDZ
Mendoza
VVI
Santa Cruz
$1,570 Roundtrip, found 1 hour ago
$1,570
Roundtrip
found 1 hour ago
Select Copa flight, departing Sat, Nov 8 from Mendoza to Santa Cruz, returning Mon, Nov 10, priced at $1,570 found 1 hour ago

Alternative airports near Santa Cruz

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Viru Viru Intl. VVI. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $724
VVI
Viru Viru Intl.
Cheapest
Average driving time to city center20 min
Flights from $724

Frequently asked questions

How much does a flight from Governor Francisco Gabrielli Intl. Airport (MDZ) to Viru Viru Intl. Airport (VVI) cost?
Grab a cheap one-way flight from $294 or cheap return flight from $500 from Governor Francisco Gabrielli Intl. Airport (MDZ) to Viru Viru Intl. Airport (VVI) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Governor Francisco Gabrielli Intl. Airport (MDZ) to Viru Viru Intl. Airport (VVI)?
Flying in December is a good way to save, as it's the cheapest month for flights between MDZ and VVI. You'll typically find the lowest fares during the off-season.
What is the cheapest airline that flies from Governor Francisco Gabrielli Intl. Airport (MDZ) to Viru Viru Intl. Airport (VVI)?
Expedia's filter tool lets you easily compare different airlines, flight durations and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to find the carrier with the cheapest MDZ to VVI flight.
How many flights per day from Governor Francisco Gabrielli Intl. Airport (MDZ) to Viru Viru Intl. Airport (VVI)?
Direct flights from Governor Francisco Gabrielli Intl. Airport (MDZ) to Viru Viru Intl. Airport (VVI) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filters. Enter your travel dates and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MDZ to VVI?
Generally you'll find the most flight options available on a Friday. Tuesdays tend to be the quietest.* But this can change based on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Governor Francisco Gabrielli Intl. Airport (MDZ) to Viru Viru Intl. Airport (VVI)?
To touch down at Viru Viru Intl. Airport (VVI) without delays, book a flight that leaves Governor Francisco Gabrielli Intl. Airport (MDZ) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Governor Francisco Gabrielli Intl. Airport (MDZ) to Viru Viru Intl. Airport (VVI) last-minute?
Last-minute fares from MDZ to VVI are usually more expensive. To secure the lowest rates, start looking for flights well ahead of time. That being said, if you're flexible with your travel dates, you may land a cheap ticket right before you leave.
Is it cheaper to book a MDZ to VVI flight and hotel package?
You can save money by booking a MDZ to VVI flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one place. Once you've chosen your preferred accommodations and flights, consider adding extras such as activities, tours and car rentals.
Can I cancel or change the date of my flight from Governor Francisco Gabrielli Intl. Airport (MDZ) to Viru Viru Intl. Airport (VVI)?
You can usually reschedule or cancel your MDZ to VVI flight. However, if it's been more than 24 hours since booking, additional charges may apply. Check your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
Governor Francisco Gabrielli Intl.
Destination airport
Viru Viru Intl.
Airlines serving
Aerolineas Argentinas, Copa, GOL Linhas Aereas S.A., LATAM Airlines Group
Roundtrip price
$500
Distance
1106 mi

Book with confidence

Mendoza to Santa Cruz Flights

The cheapest times to fly from Mendoza to Santa Cruz

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mendoza to Santa Cruz are during the month of December. You can find some of the cheapest flights from Mendoza to Santa Cruz with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Mendoza to Santa Cruz

Sunday is one of the best days to book for cheap flights from Mendoza to Santa Cruz: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Mendoza to Santa Cruz

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mendoza to Santa Cruz in 2025. You can also book with separate airlines for your outbound and return journeys, from $294 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mendoza to Santa Cruz flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mendoza to Santa Cruz airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Mendoza to Santa Cruz Flights

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*Available to One Key members.