$546 Cheap Flights from Minneapolis (MSP) to Sao Luis (SLZ)

View $546 flight on Mon, Mar 30, 2026Opens in a new window

Popular airlines from Minneapolis - St. Paul Intl. Airport (MSP) to Sao Luis (SLZ-Marechal Cunha Machado Intl.)

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Cheap Flights from Minneapolis to Sao Luis (MSP-SLZ)

Prices were available within the past 7 days and start at $546 for one-way flights and $1,167 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Air Canada
Mon, Mar 30 - Sat, Apr 4
MSP
Minneapolis
SLZ
São Luís
$1,167 Roundtrip, found 19 hours ago
$1,167
Roundtrip
found 19 hours ago
Select Air Canada flight, departing Mon, Mar 30 from Minneapolis to São Luís, returning Sat, Apr 4, priced at $1,167 found 19 hours ago
American Airlines
Mon, Mar 30 - Sat, Apr 4
MSP
Minneapolis
SLZ
São Luís
$1,210 Roundtrip, found 19 hours ago
$1,210
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Mon, Mar 30 from Minneapolis to São Luís, returning Sat, Apr 4, priced at $1,210 found 19 hours ago
Air Canada
Mon, Mar 30 - Sat, Apr 4
MSP
Minneapolis
SLZ
São Luís
$1,227 Roundtrip, found 19 hours ago
$1,227
Roundtrip
found 19 hours ago
Select Air Canada flight, departing Mon, Mar 30 from Minneapolis to São Luís, returning Sat, Apr 4, priced at $1,227 found 19 hours ago
United
Mon, Mar 30 - Sat, Apr 4
MSP
Minneapolis
SLZ
São Luís
$1,235 Roundtrip, found 19 hours ago
$1,235
Roundtrip
found 19 hours ago
Select United flight, departing Mon, Mar 30 from Minneapolis to São Luís, returning Sat, Apr 4, priced at $1,235 found 19 hours ago
United
Mon, Mar 30 - Sat, Apr 4
MSP
Minneapolis
SLZ
São Luís
$1,248 Roundtrip, found 19 hours ago
$1,248
Roundtrip
found 19 hours ago
Select United flight, departing Mon, Mar 30 from Minneapolis to São Luís, returning Sat, Apr 4, priced at $1,248 found 19 hours ago
American Airlines
Mon, Mar 30 - Sat, Apr 4
MSP
Minneapolis
SLZ
São Luís
$1,275 Roundtrip, found 19 hours ago
$1,275
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Mon, Mar 30 from Minneapolis to São Luís, returning Sat, Apr 4, priced at $1,275 found 19 hours ago
American Airlines
Mon, Mar 30 - Sat, Apr 4
MSP
Minneapolis
SLZ
São Luís
$1,305 Roundtrip, found 19 hours ago
$1,305
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Mon, Mar 30 from Minneapolis to São Luís, returning Sat, Apr 4, priced at $1,305 found 19 hours ago
Air Canada
Mon, Mar 30 - Sat, Apr 4
MSP
Minneapolis
SLZ
São Luís
$1,307 Roundtrip, found 19 hours ago
$1,307
Roundtrip
found 19 hours ago
Select Air Canada flight, departing Mon, Mar 30 from Minneapolis to São Luís, returning Sat, Apr 4, priced at $1,307 found 19 hours ago
Air Canada
Wed, Dec 3 - Wed, Dec 10
MSP
Minneapolis
SLZ
São Luís
$1,313 Roundtrip, found 1 day ago
$1,313
Roundtrip
found 1 day ago
Select Air Canada flight, departing Wed, Dec 3 from Minneapolis to São Luís, returning Wed, Dec 10, priced at $1,313 found 1 day ago
LATAM Airlines Group
Mon, Aug 10 - Tue, Aug 25
MSP
Minneapolis
SLZ
São Luís
$1,440 Roundtrip, found 1 day ago
$1,440
Roundtrip
found 1 day ago
Select LATAM Airlines Group flight, departing Mon, Aug 10 from Minneapolis to São Luís, returning Tue, Aug 25, priced at $1,440 found 1 day ago
Flights from Minneapolis (MSP) to Sao Luis (SLZ)
Origin airport
Minneapolis - St. Paul Intl.
Destination airport
Marechal Cunha Machado Intl.
Airlines serving
American Airlines, LATAM Airlines Group
Roundtrip price
$1,166
Distance
4446 mi

Minneapolis to Sao Luis Flights

The cheapest times to fly from Minneapolis to Sao Luis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Minneapolis to Sao Luis are during the month of March. You can find some of the cheapest flights from Minneapolis to Sao Luis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Minneapolis to Sao Luis

Sunday is one of the best days to book for cheap flights from Minneapolis to Sao Luis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Minneapolis to Sao Luis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Minneapolis to Sao Luis in 2025. You can also book with separate airlines for your outbound and return journeys, from $546 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Minneapolis to Sao Luis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Minneapolis to Sao Luis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Minneapolis - St. Paul Intl. Airport (MSP) to Marechal Cunha Machado Intl. Airport (SLZ) cost?
Lock in a cheap one-way flight from $546 or cheap return flight from $1,167 from Minneapolis - St. Paul Intl. Airport (MSP) to Marechal Cunha Machado Intl. Airport (SLZ) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Minneapolis - St. Paul Intl. Airport (MSP) to Marechal Cunha Machado Intl. Airport (SLZ)?
The cheapest month to fly from MSP to SLZ is March, when demand is low. Off-peak months are generally when you'll find lower airfares between these airports.
What is the cheapest airline that flies from Minneapolis - St. Paul Intl. Airport (MSP) to Marechal Cunha Machado Intl. Airport (SLZ)?
To find the cheapest airline flying from MSP to SLZ, use Expedia's filter tool. Tailor your search based on what matters most to you, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Minneapolis - St. Paul Intl. Airport (MSP) to Marechal Cunha Machado Intl. Airport (SLZ)?
Direct flights from Minneapolis - St. Paul Intl. Airport (MSP) to Marechal Cunha Machado Intl. Airport (SLZ) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filters. Enter your dates and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MSP to SLZ?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can vary depending on a number of factors, such as the season and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Minneapolis - St. Paul Intl. Airport (MSP) to Marechal Cunha Machado Intl. Airport (SLZ)?
To touch down at Marechal Cunha Machado Intl. Airport (SLZ) without delays, select a flight that takes off from Minneapolis - St. Paul Intl. Airport (MSP) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Minneapolis - St. Paul Intl. Airport (MSP) to Marechal Cunha Machado Intl. Airport (SLZ) last-minute?
Waiting until right before your break to book a ticket from MSP to SLZ generally means paying more. Although you may find some last-minute deals, there's no guarantee. Keep your travel schedule open to maximize your chances of landing a bargain.
Is it cheaper to book a MSP to SLZ flight and hotel package?
Opting for a MSP to SLZ flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Choose from our extensive range of accommodations and then add car rentals, flights and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Minneapolis - St. Paul Intl. Airport (MSP) to Marechal Cunha Machado Intl. Airport (SLZ)?
It's usually possible to cancel or reschedule your MSP to SLZ flight. However, for bookings made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more information on our Customer Service portal.

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*Available to One Key members.