$140 Cheap Flights from Myrtle Beach (MYR) to Harrisburg (MDT)

View $140 flight on Tue, Oct 7, 2025Opens in a new window

Popular airlines from Myrtle Beach Intl. Airport (MYR) to Harrisburg Intl. Airport (MDT)

Cheap Flights from Myrtle Beach to Harrisburg (MYR-MDT)

Prices were available within the past 7 days and start at $140 for one-way flights and $251 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Oct 7 - Sat, Oct 18
MYR
Myrtle Beach
MDT
Harrisburg
$251 Roundtrip, found 1 day ago
$251
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Oct 7 from Myrtle Beach to Harrisburg, returning Sat, Oct 18, priced at $251 found 1 day ago
American Airlines
Sun, Aug 31 - Tue, Sep 30
MYR
Myrtle Beach
MDT
Harrisburg
$255 Roundtrip, found 2 days ago
$255
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Aug 31 from Myrtle Beach to Harrisburg, returning Tue, Sep 30, priced at $255 found 2 days ago
Delta
Wed, Nov 19 - Tue, Dec 2
MYR
Myrtle Beach
MDT
Harrisburg
$259 Roundtrip, found 4 hours ago
$259
Roundtrip
found 4 hours ago
Select Delta flight, departing Wed, Nov 19 from Myrtle Beach to Harrisburg, returning Tue, Dec 2, priced at $259 found 4 hours ago
Delta
Tue, Jan 13 - Sat, Jan 24
MYR
Myrtle Beach
MDT
Harrisburg
$264 Roundtrip, found 2 days ago
$264
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Jan 13 from Myrtle Beach to Harrisburg, returning Sat, Jan 24, priced at $264 found 2 days ago
Delta
Thu, Oct 9 - Sat, Oct 18
MYR
Myrtle Beach
MDT
Harrisburg
$279 Roundtrip, found 1 day ago
$279
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Oct 9 from Myrtle Beach to Harrisburg, returning Sat, Oct 18, priced at $279 found 1 day ago
Delta
Thu, Dec 4 - Tue, Dec 9
MYR
Myrtle Beach
MDT
Harrisburg
$283 Roundtrip, found 1 day ago
$283
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Dec 4 from Myrtle Beach to Harrisburg, returning Tue, Dec 9, priced at $283 found 1 day ago
Delta
Sat, Nov 1 - Tue, Nov 18
MYR
Myrtle Beach
MDT
Harrisburg
$284 Roundtrip, found 3 days ago
$284
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, Nov 1 from Myrtle Beach to Harrisburg, returning Tue, Nov 18, priced at $284 found 3 days ago
Delta
Thu, Jan 8 - Sat, Jan 24
MYR
Myrtle Beach
MDT
Harrisburg
$288 Roundtrip, found 2 days ago
$288
Roundtrip
found 2 days ago
Select Delta flight, departing Thu, Jan 8 from Myrtle Beach to Harrisburg, returning Sat, Jan 24, priced at $288 found 2 days ago
Delta
Tue, Aug 26 - Wed, Sep 17
MYR
Myrtle Beach
MDT
Harrisburg
$290 Roundtrip, found 3 days ago
$290
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Aug 26 from Myrtle Beach to Harrisburg, returning Wed, Sep 17, priced at $290 found 3 days ago
United
Fri, Aug 29 - Sun, Aug 31
MYR
Myrtle Beach
MDT
Harrisburg
$358 Roundtrip, found 4 hours ago
$358
Roundtrip
found 4 hours ago
Select United flight, departing Fri, Aug 29 from Myrtle Beach to Harrisburg, returning Sun, Aug 31, priced at $358 found 4 hours ago

Find the cheapest month to fly from Myrtle Beach (MYR) to Harrisburg (MDT)

May is typically the cheapest month to fly

From $200 - $556 per traveler.

Graph displaying average flight prices per month

Alternative airports near Harrisburg

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lancaster, PA LNS. Average driving time to city center is 48 minutes. Flights from $453
LNS
Lancaster, PA
Average driving time to city center48 min
Flights from $453
Flights from Myrtle Beach (MYR) to Harrisburg (MDT)
Origin airport
Myrtle Beach Intl.
Destination airport
Harrisburg Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$250
Distance
465 mi
Average flight time
1 hour 35 mins

Myrtle Beach to Harrisburg Flights

The cheapest times to fly from Myrtle Beach to Harrisburg

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Myrtle Beach to Harrisburg are during the month of October. You can find some of the cheapest flights from Myrtle Beach to Harrisburg with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Myrtle Beach to Harrisburg

Sunday is one of the best days to book for cheap flights from Myrtle Beach to Harrisburg: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Myrtle Beach to Harrisburg

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Myrtle Beach to Harrisburg in 2025. You can also book with separate airlines for your outbound and return journeys, from $140 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Myrtle Beach to Harrisburg flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Myrtle Beach to Harrisburg airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Myrtle Beach Intl. Airport (MYR) to Harrisburg Intl. Airport (MDT) cost?
Secure a cheap one-way flight from $140 or cheap return flight from $251 from Myrtle Beach Intl. Airport (MYR) to Harrisburg Intl. Airport (MDT) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Myrtle Beach Intl. Airport (MYR) to Harrisburg Intl. Airport (MDT)?
October is the most affordable month to fly from MYR to MDT. Timing your trip outside of the busy season is often the key to finding better deals on flights.
What is the cheapest airline that flies from Myrtle Beach Intl. Airport (MYR) to Harrisburg Intl. Airport (MDT)?
To find the cheapest airline that'll fly you from MYR to MDT, use Expedia's filter tool. Customize your search based on your travel style, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Myrtle Beach Intl. Airport (MYR) to Harrisburg Intl. Airport (MDT)?
You'll have to catch a flight with a layover when traveling from Myrtle Beach Intl. Airport (MYR) to Harrisburg Intl. Airport (MDT). There are no daily direct flights on this route. However, simply filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from MYR to MDT?
Friday is usually the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can vary based on various factors, including the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Myrtle Beach Intl. Airport (MYR) to Harrisburg Intl. Airport (MDT)?
Select a flight from Myrtle Beach Intl. Airport (MYR) to Harrisburg Intl. Airport (MDT) that takes off before 3 PM to reduce the risk of cancellations. Departures later than this are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Myrtle Beach Intl. Airport (MYR) to Harrisburg Intl. Airport (MDT) last-minute?
Booking your plane ticket from MYR to MDT right before your getaway is usually more expensive. However, if you're flexible with your schedule, you could land a cheap last-minute fare.
Is it cheaper to book a MYR to MDT flight and hotel package?
Compared with arranging hotels and flights separately, booking a MYR to MDT flight and hotel package with Expedia could lead to significant savings. What's more, having everything in one convenient place will take the hassle out of planning your trip. Simply secure your flights and choose from our wide range of stays, then customize your trip with extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from Myrtle Beach Intl. Airport (MYR) to Harrisburg Intl. Airport (MDT)?
If you reserved your MYR to MDT flight within the last 24 hours, you may be able to cancel or modify it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for more details.

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*Available to One Key members.