$150 Cheap Flights from Myrtle Beach (MYR) to Harrisburg (MDT)

View $150 flight on Wed, Dec 10, 2025Opens in a new window

Popular airlines from Myrtle Beach Intl. Airport (MYR) to Harrisburg Intl. Airport (MDT)

Cheap Flights from Myrtle Beach to Harrisburg (MYR-MDT)

Prices were available within the past 7 days and start at $150 for one-way flights and $259 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Dec 2 - Tue, Dec 9
MYR
Myrtle Beach
MDT
Harrisburg
$259 Roundtrip, found 19 hours ago
$259
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Tue, Dec 2 from Myrtle Beach to Harrisburg, returning Tue, Dec 9, priced at $259 found 19 hours ago
United
Fri, Oct 17 - Thu, Oct 23
MYR
Myrtle Beach
MDT
Harrisburg
$264 Roundtrip, found 1 day ago
$264
Roundtrip
found 1 day ago
Select United flight, departing Fri, Oct 17 from Myrtle Beach to Harrisburg, returning Thu, Oct 23, priced at $264 found 1 day ago
American Airlines
Fri, Oct 31 - Wed, Nov 5
MYR
Myrtle Beach
MDT
Harrisburg
$264 Roundtrip, found 13 hours ago
$264
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Fri, Oct 31 from Myrtle Beach to Harrisburg, returning Wed, Nov 5, priced at $264 found 13 hours ago
Delta
Sat, Jan 24 - Sat, Feb 7
MYR
Myrtle Beach
MDT
Harrisburg
$269 Roundtrip, found 22 hours ago
$269
Roundtrip
found 22 hours ago
Select Delta flight, departing Sat, Jan 24 from Myrtle Beach to Harrisburg, returning Sat, Feb 7, priced at $269 found 22 hours ago
United
Tue, Apr 7 - Tue, Apr 21
MYR
Myrtle Beach
MDT
Harrisburg
$275 Roundtrip, found 3 days ago
$275
Roundtrip
found 3 days ago
Select United flight, departing Tue, Apr 7 from Myrtle Beach to Harrisburg, returning Tue, Apr 21, priced at $275 found 3 days ago
Delta
Tue, Dec 2 - Tue, Dec 9
MYR
Myrtle Beach
MDT
Harrisburg
$283 Roundtrip, found 19 hours ago
$283
Roundtrip
found 19 hours ago
Select Delta flight, departing Tue, Dec 2 from Myrtle Beach to Harrisburg, returning Tue, Dec 9, priced at $283 found 19 hours ago
Delta
Sat, Jan 24 - Tue, Feb 3
MYR
Myrtle Beach
MDT
Harrisburg
$288 Roundtrip, found 22 hours ago
$288
Roundtrip
found 22 hours ago
Select Delta flight, departing Sat, Jan 24 from Myrtle Beach to Harrisburg, returning Tue, Feb 3, priced at $288 found 22 hours ago
Delta
Fri, Dec 5 - Tue, Dec 9
MYR
Myrtle Beach
MDT
Harrisburg
$293 Roundtrip, found 19 hours ago
$293
Roundtrip
found 19 hours ago
Select Delta flight, departing Fri, Dec 5 from Myrtle Beach to Harrisburg, returning Tue, Dec 9, priced at $293 found 19 hours ago
Delta
Tue, Oct 14 - Fri, Oct 31
MYR
Myrtle Beach
MDT
Harrisburg
$294 Roundtrip, found 1 day ago
$294
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Oct 14 from Myrtle Beach to Harrisburg, returning Fri, Oct 31, priced at $294 found 1 day ago
Delta
Sat, Jan 31 - Sun, Feb 15
MYR
Myrtle Beach
MDT
Harrisburg
$294 Roundtrip, found 22 hours ago
$294
Roundtrip
found 22 hours ago
Select Delta flight, departing Sat, Jan 31 from Myrtle Beach to Harrisburg, returning Sun, Feb 15, priced at $294 found 22 hours ago

Find the cheapest month to fly from Myrtle Beach (MYR) to Harrisburg (MDT)

May is typically the cheapest month to fly

From $200 - $537 per traveler.

Alternative airports near Harrisburg

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Harrisburg Intl. MDT. Cheapest option available. Average driving time to city center is 16 minutes. Flights from $329
MDT
Harrisburg Intl.
Cheapest
Average driving time to city center16 min
Flights from $329

Frequently asked questions

How much does a flight from Myrtle Beach Intl. Airport (MYR) to Harrisburg Intl. Airport (MDT) cost?
Secure a cheap one-way flight from $150 or cheap return flight from $259 from Myrtle Beach Intl. Airport (MYR) to Harrisburg Intl. Airport (MDT) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Myrtle Beach Intl. Airport (MYR) to Harrisburg Intl. Airport (MDT)?
December is the most affordable month to fly from MYR to MDT. Timing your trip outside of the busy season is often the key to finding better deals on flights.
What is the cheapest airline that flies from Myrtle Beach Intl. Airport (MYR) to Harrisburg Intl. Airport (MDT)?
To find the cheapest airline that'll fly you from MYR to MDT, use Expedia's filter tool. Customize your search based on your travel style, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Myrtle Beach Intl. Airport (MYR) to Harrisburg Intl. Airport (MDT)?
You'll have to catch a flight with a layover when traveling from Myrtle Beach Intl. Airport (MYR) to Harrisburg Intl. Airport (MDT). There are no daily direct flights on this route. However, simply filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from MYR to MDT?
Friday is usually the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can vary based on various factors, including the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Myrtle Beach Intl. Airport (MYR) to Harrisburg Intl. Airport (MDT)?
Select a flight from Myrtle Beach Intl. Airport (MYR) to Harrisburg Intl. Airport (MDT) that takes off before 3 PM to reduce the risk of cancellations. Departures later than this are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Myrtle Beach Intl. Airport (MYR) to Harrisburg Intl. Airport (MDT) last-minute?
Booking your plane ticket from MYR to MDT right before your getaway is usually more expensive. However, if you're flexible with your schedule, you could land a cheap last-minute fare.
Is it cheaper to book a MYR to MDT flight and hotel package?
Compared with arranging hotels and flights separately, booking a MYR to MDT flight and hotel package with Expedia could lead to significant savings. What's more, having everything in one convenient place will take the hassle out of planning your trip. Simply secure your flights and choose from our wide range of stays, then customize your trip with extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from Myrtle Beach Intl. Airport (MYR) to Harrisburg Intl. Airport (MDT)?
If you reserved your MYR to MDT flight within the last 24 hours, you may be able to cancel or modify it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for more details.

Travel information

Travel information

Origin airport
Myrtle Beach Intl.
Destination airport
Harrisburg Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$258
Distance
465 mi
Average flight time
1 hour 35 mins

Book with confidence

Book with confidence

Myrtle Beach to Harrisburg Flights

The cheapest times to fly from Myrtle Beach to Harrisburg

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Myrtle Beach to Harrisburg are during the month of December. You can find some of the cheapest flights from Myrtle Beach to Harrisburg with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Myrtle Beach to Harrisburg

Sunday is one of the best days to book for cheap flights from Myrtle Beach to Harrisburg: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Myrtle Beach to Harrisburg

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Myrtle Beach to Harrisburg in 2025. You can also book with separate airlines for your outbound and return journeys, from $150 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Myrtle Beach to Harrisburg flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Myrtle Beach to Harrisburg airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Myrtle Beach to Harrisburg Flights

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*Available to One Key members.