$390 Cheap Flights from Mazatlan (MZT) to Panama City (PTY)

View $390 flight on Fri, Oct 24, 2025Opens in a new window

Popular airlines from General Rafael Buelna Intl. Airport (MZT) to Tocumen Intl. Airport (PTY)

Cheap Flights from Mazatlan to Panama City (MZT-PTY)

Prices were available within the past 7 days and start at $390 for one-way flights and $629 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Fri, Nov 21 - Wed, Nov 26
MZT
Mazatlán
PTY
Panama City
$629 Roundtrip, found 1 day ago
$629
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Fri, Nov 21 from Mazatlán to Panama City, returning Wed, Nov 26, priced at $629 found 1 day ago
Aeromexico
Wed, Dec 31 - Fri, Jan 9
MZT
Mazatlán
PTY
Panama City
$635 Roundtrip, found 5 days ago
$635
Roundtrip
found 5 days ago
Select Aeromexico flight, departing Wed, Dec 31 from Mazatlán to Panama City, returning Fri, Jan 9, priced at $635 found 5 days ago
Aeromexico
Wed, Dec 3 - Wed, Dec 10
MZT
Mazatlán
PTY
Panama City
$676 Roundtrip, found 3 days ago
$676
Roundtrip
found 3 days ago
Select Aeromexico flight, departing Wed, Dec 3 from Mazatlán to Panama City, returning Wed, Dec 10, priced at $676 found 3 days ago
Aeromexico
Tue, Jan 6 - Fri, Jan 16
MZT
Mazatlán
PTY
Panama City
$677 Roundtrip, found 4 days ago
$677
Roundtrip
found 4 days ago
Select Aeromexico flight, departing Tue, Jan 6 from Mazatlán to Panama City, returning Fri, Jan 16, priced at $677 found 4 days ago
Aeromexico
Fri, Dec 5 - Thu, Dec 11
MZT
Mazatlán
PTY
Panama City
$686 Roundtrip, found 2 days ago
$686
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Fri, Dec 5 from Mazatlán to Panama City, returning Thu, Dec 11, priced at $686 found 2 days ago
Aeromexico
Fri, Dec 5 - Thu, Dec 11
MZT
Mazatlán
PTY
Panama City
$687 Roundtrip, found 2 days ago
$687
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Fri, Dec 5 from Mazatlán to Panama City, returning Thu, Dec 11, priced at $687 found 2 days ago
Aeromexico
Tue, Jan 6 - Sun, Jan 11
MZT
Mazatlán
PTY
Panama City
$688 Roundtrip, found 4 days ago
$688
Roundtrip
found 4 days ago
Select Aeromexico flight, departing Tue, Jan 6 from Mazatlán to Panama City, returning Sun, Jan 11, priced at $688 found 4 days ago
WestJet
Fri, Jan 2 - Thu, Jan 8
MZT
Mazatlán
PTY
Panama City
$835 Roundtrip, found 4 days ago
$835
Roundtrip
found 4 days ago
Select WestJet flight, departing Fri, Jan 2 from Mazatlán to Panama City, returning Thu, Jan 8, priced at $835 found 4 days ago
American Airlines
Wed, Dec 3 - Wed, Dec 10
MZT
Mazatlán
PTY
Panama City
$1,019 Roundtrip, found 3 days ago
$1,019
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Dec 3 from Mazatlán to Panama City, returning Wed, Dec 10, priced at $1,019 found 3 days ago
United
Sat, Jan 3 - Fri, Jan 9
MZT
Mazatlán
PTY
Panama City
$2,239 Roundtrip, found 2 days ago
$2,239
Roundtrip
found 2 days ago
Select United flight, departing Sat, Jan 3 from Mazatlán to Panama City, returning Fri, Jan 9, priced at $2,239 found 2 days ago

Frequently asked questions

How much does a flight from General Rafael Buelna Intl. Airport (MZT) to Tocumen Intl. Airport (PTY) cost?
Snag a cheap one-way flight from $390 or cheap return flight from $629 from General Rafael Buelna Intl. Airport (MZT) to Tocumen Intl. Airport (PTY) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from General Rafael Buelna Intl. Airport (MZT) to Tocumen Intl. Airport (PTY)?
The cheapest month to fly from MZT to PTY is November, when demand is low. Off-peak season is often when you'll find lower airfares between these airports.
What is the cheapest airline that flies from General Rafael Buelna Intl. Airport (MZT) to Tocumen Intl. Airport (PTY)?
Use the filter tool on Expedia to compare different airlines and find the most affordable carrier that'll fly you from MZT to PTY. Then, sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from General Rafael Buelna Intl. Airport (MZT) to Tocumen Intl. Airport (PTY)?
Nonstop flights from General Rafael Buelna Intl. Airport (MZT) to Tocumen Intl. Airport (PTY) aren't available daily, so you'll have to take a flight with a layover. Explore your options with our filter tool. Enter your travel dates and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MZT to PTY?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can change depending on a number of factors, such as the season and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from General Rafael Buelna Intl. Airport (MZT) to Tocumen Intl. Airport (PTY)?
To touch down at Tocumen Intl. Airport (PTY) on schedule, opt for a flight that leaves from General Rafael Buelna Intl. Airport (MZT) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from General Rafael Buelna Intl. Airport (MZT) to Tocumen Intl. Airport (PTY) last-minute?
Last-minute bookings from MZT to PTY are usually more expensive. To secure the best prices, start looking for flights well ahead of time. That being said, if you're flexible with your travel plans, it's possible to land a cheap ticket right before you leave.
Is it cheaper to book a MZT to PTY flight and hotel package?
Compared with arranging hotels and flights separately, booking a MZT to PTY flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one place will take the stress out of planning your trip. Simply secure your flights and choose from our wide range of hotels, then personalize your trip with extras like tours and car rentals.
Can I cancel or change the date of my flight from General Rafael Buelna Intl. Airport (MZT) to Tocumen Intl. Airport (PTY)?
Typically, you can reschedule or cancel your MZT to PTY flight. However, there may be additional fees, especially if you made your booking more than 24 hours ago. Check your itinerary for the airline's rules and fees on flight changes, or if you need more details, go to our Customer Service portal.

Travel information

Travel information

Origin airport
General Rafael Buelna Intl.
Destination airport
Tocumen Intl.
Airlines serving
Aeromexico
Roundtrip price
$628
Distance
2026 mi

Book with confidence

Book with confidence

Mazatlan to Panama City Flights

The cheapest times to fly from Mazatlan to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mazatlan to Panama City are during the month of November. You can find some of the cheapest flights from Mazatlan to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Mazatlan to Panama City

Sunday is one of the best days to book for cheap flights from Mazatlan to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Mazatlan to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mazatlan to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $390 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mazatlan to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mazatlan to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Mazatlan to Panama City Flights

Explore a world of travel with Expedia

Explore a world of travel with Expedia

*Available to One Key members.