$266 Cheap Flights from Portland (PDX) to Panama City (PTY)

View $266 flight on Wed, Nov 12, 2025Opens in a new window

Popular airlines from Portland International Airport (PDX) to Tocumen Intl. Airport (PTY)

Cheap Flights from Portland to Panama City (PDX-PTY)

Prices were available within the past 7 days and start at $266 for one-way flights and $577 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Wed, Mar 4 - Wed, Mar 11
PDX
Portland
PTY
Panama City
$577 Roundtrip, found 12 hours ago
$577
Roundtrip
found 12 hours ago
Select United flight, departing Wed, Mar 4 from Portland to Panama City, returning Wed, Mar 11, priced at $577 found 12 hours ago
United
Wed, Feb 25 - Wed, Mar 11
PDX
Portland
PTY
Panama City
$581 Roundtrip, found 1 day ago
$581
Roundtrip
found 1 day ago
Select United flight, departing Wed, Feb 25 from Portland to Panama City, returning Wed, Mar 11, priced at $581 found 1 day ago
United
Wed, Jan 28 - Wed, Feb 11
PDX
Portland
PTY
Panama City
$585 Roundtrip, found 5 hours ago
$585
Roundtrip
found 5 hours ago
Select United flight, departing Wed, Jan 28 from Portland to Panama City, returning Wed, Feb 11, priced at $585 found 5 hours ago
United
Wed, May 20 - Wed, May 27
PDX
Portland
PTY
Panama City
$591 Roundtrip, found 6 hours ago
$591
Roundtrip
found 6 hours ago
Select United flight, departing Wed, May 20 from Portland to Panama City, returning Wed, May 27, priced at $591 found 6 hours ago
United
Tue, Jan 27 - Sat, Jan 31
PDX
Portland
PTY
Panama City
$596 Roundtrip, found 1 hour ago
$596
Roundtrip
found 1 hour ago
Select United flight, departing Tue, Jan 27 from Portland to Panama City, returning Sat, Jan 31, priced at $596 found 1 hour ago
United
Wed, Nov 12 - Tue, Nov 18
PDX
Portland
PTY
Panama City
$598 Roundtrip, found 21 hours ago
$598
Roundtrip
found 21 hours ago
Select United flight, departing Wed, Nov 12 from Portland to Panama City, returning Tue, Nov 18, priced at $598 found 21 hours ago
Delta
Tue, Jan 6 - Wed, Jan 14
PDX
Portland
PTY
Panama City
$628 Roundtrip, just found
$628
Roundtrip
just found
Select Delta flight, departing Tue, Jan 6 from Portland to Panama City, returning Wed, Jan 14, priced at $628 just found
American Airlines
Wed, Mar 18 - Tue, Mar 24
PDX
Portland
PTY
Panama City
$637 Roundtrip, found 2 days ago
$637
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Mar 18 from Portland to Panama City, returning Tue, Mar 24, priced at $637 found 2 days ago
Copa
Fri, Apr 3 - Wed, Apr 8
PDX
Portland
PTY
Panama City
$740 Roundtrip, found 1 hour ago
$740
Roundtrip
found 1 hour ago
Select Copa flight, departing Fri, Apr 3 from Portland to Panama City, returning Wed, Apr 8, priced at $740 found 1 hour ago
avianca
Mon, Jan 26 - Tue, Feb 17
PDX
Portland
PTY
Panama City
$1,032 Roundtrip, found 15 hours ago
$1,032
Roundtrip
found 15 hours ago
Select avianca flight, departing Mon, Jan 26 from Portland to Panama City, returning Tue, Feb 17, priced at $1,032 found 15 hours ago

Find the cheapest month to fly from Portland (PDX) to Panama City (PTY)

August is typically the cheapest month to fly

From $480 - $914 per traveler.

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tocumen Intl. PTY. Cheapest option available. Average driving time to city center is 16 minutes. Flights from $658
PTY
Tocumen Intl.
Cheapest
Average driving time to city center16 min
Flights from $658
Flights from Portland (PDX) to Panama City (PTY)
Origin airport
Portland Intl.
Destination airport
Tocumen Intl.
Airlines serving
American Airlines, Copa, Delta, United, avianca
Roundtrip price
$577
Distance
3589 mi

Portland to Panama City Flights

The cheapest times to fly from Portland to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Portland to Panama City are during the month of March. You can find some of the cheapest flights from Portland to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Portland to Panama City

Sunday is one of the best days to book for cheap flights from Portland to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Portland to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Portland to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $266 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Portland to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Portland to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Portland Intl. Airport (PDX) to Tocumen Intl. Airport (PTY) cost?
Secure a cheap one-way flight from $266 or cheap return flight from $577 from Portland Intl. Airport (PDX) to Tocumen Intl. Airport (PTY) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Portland Intl. Airport (PDX) to Tocumen Intl. Airport (PTY)?
March is the least expensive month to fly from PDX to PTY. Avoiding peak travel times is often the key to landing a great deal.
What is the cheapest airline that flies from Portland Intl. Airport (PDX) to Tocumen Intl. Airport (PTY)?
To find the cheapest airline flying from PDX to PTY, use Expedia's filter tool. Tailor your search based on your travel needs, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from Portland Intl. Airport (PDX) to Tocumen Intl. Airport (PTY)?
You'll need to catch a flight with a layover when traveling from Portland Intl. Airport (PDX) to Tocumen Intl. Airport (PTY). There are no daily direct flights on this route. However, just filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from PDX to PTY?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Portland Intl. Airport (PDX) to Tocumen Intl. Airport (PTY)?
To reach Tocumen Intl. Airport (PTY) without delays, select a flight that leaves Portland Intl. Airport (PDX) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Portland Intl. Airport (PDX) to Tocumen Intl. Airport (PTY) last-minute?
Last-minute bookings from PDX to PTY are usually more expensive. To secure the lowest rates, start searching for flights early. That being said, if you're flexible with your travel plans, it's possible to land a cheap fare right before your trip.
Is it cheaper to book a PDX to PTY flight and hotel package?
You'll generally save money by securing a PDX to PTY flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. After choosing your ideal flights and accommodations, consider other add-ons like activities, tours and car rentals.
Can I cancel or change the date of my flight from Portland Intl. Airport (PDX) to Tocumen Intl. Airport (PTY)?
You can usually reschedule or cancel your PDX to PTY flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find more details on our Customer Service portal.

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*Available to One Key members.