$27 Cheap Flights from Pisa (PSA) to Brussels (BRU)

View $27 flight on Tue, Apr 21, 2026Opens in a new window

Popular airlines from Galileo Galilei Airport (PSA) to Brussels Airport (BRU)

Cheap Flights from Pisa to Brussels (PSA-BRU)

Prices were available within the past 7 days and start at $27 for one-way flights and $95 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Ryanair
Sat, Apr 4 - Tue, Apr 7
PSA
Pisa
BRU
Brussels
$95 Roundtrip, found 3 days ago
$95
Roundtrip
found 3 days ago
Select Ryanair flight, departing Sat, Apr 4 from Pisa to Brussels, returning Tue, Apr 7, priced at $95 found 3 days ago
Lufthansa
Tue, Apr 21 - Mon, Apr 27
PSA
Pisa
BRU
Brussels
$193 Roundtrip, found 1 day ago
$193
Roundtrip
found 1 day ago
Select Lufthansa flight, departing Tue, Apr 21 from Pisa to Brussels, returning Mon, Apr 27, priced at $193 found 1 day ago
KLM
Sat, Apr 4 - Tue, Apr 7
PSA
Pisa
BRU
Brussels
$269 Roundtrip, found 3 days ago
$269
Roundtrip
found 3 days ago
Select KLM flight, departing Sat, Apr 4 from Pisa to Brussels, returning Tue, Apr 7, priced at $269 found 3 days ago
Scandinavian Airlines
Thu, Apr 16 - Sun, Apr 19
PSA
Pisa
BRU
Brussels
$286 Roundtrip, found 2 days ago
$286
Roundtrip
found 2 days ago
Select Scandinavian Airlines flight, departing Thu, Apr 16 from Pisa to Brussels, returning Sun, Apr 19, priced at $286 found 2 days ago
British Airways
Thu, Mar 26 - Mon, Mar 30
PSA
Pisa
BRU
Brussels
$366 Roundtrip, found 2 days ago
$366
Roundtrip
found 2 days ago
Select British Airways flight, departing Thu, Mar 26 from Pisa to Brussels, returning Mon, Mar 30, priced at $366 found 2 days ago

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Alternative airports near Brussels

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Brussels South Charleroi CRL. Cheapest option available. Average driving time to city center is 42 minutes. Flights from $56
CRL
Brussels South Charleroi
Cheapest
Average driving time to city center42 min
Flights from $56

Frequently asked questions

How much does a flight from Pisa (PSA-Galileo Galilei) to Brussels (BRU-Brussels - National) cost?
You can find cheap one-way flights from $27 and cheap return flights from $95 Pisa (PSA-Galileo Galilei) to Brussels (BRU-Brussels - National) with Expedia. One-way flights usually range from $20 to $1419, and return flights typically cost between $75 and $1677. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Pisa (PSA-Galileo Galilei) to Brussels (BRU-Brussels - National) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Pisa (PSA-Galileo Galilei) to Brussels (BRU-Brussels - National)?
The cheapest month to fly from PSA to BRU is April when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Pisa (PSA-Galileo Galilei) to Brussels (BRU-Brussels - National)?
Ryanair operates around 7 direct flights from PSA to BRU every week.
What is the cheapest airline that flies from Pisa (PSA-Galileo Galilei) to Brussels (BRU-Brussels - National)?
Ryanair is one of the cheapest airlines offering nonstop flights from Pisa (PSA) to Brussels (BRU), with tickets starting from around $82 for a round-trip ticket. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Pisa (PSA-Galileo Galilei) to Brussels (BRU-Brussels - National)?
To find a cheap flight from Pisa (PSA-Galileo Galilei) to Brussels (BRU-Brussels - National), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Pisa (PSA-Galileo Galilei) to Brussels (BRU-Brussels - National)?
The best airline to fly with from Pisa (PSA) to Brussels (BRU) will differ from traveler to traveler. If you like to fly early, Ryanair offers early morning flights. If price is the most important factor, Ryanair typically offers the lowest fares. Air Dolomiti offers the most daily flights from Pisa to Brussels, which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Pisa (PSA-Galileo Galilei) to Brussels (BRU-Brussels - National)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Pisa (PSA-Galileo Galilei) to Brussels (BRU-Brussels - National)?
You can find approximately 1 nonstop flights per day from Galileo Galilei (PSA) to Brussels - National (BRU). For more options, look at flights that include layovers.
What is the earliest flight from Pisa (PSA-Galileo Galilei) to Brussels (BRU-Brussels - National)?
Sort flights by "Departure (earliest)" on Expedia to find the earliest flight from PSA to BRU. To compare more early flights, use the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Pisa (PSA-Galileo Galilei) to Brussels (BRU-Brussels - National)?
The most popular departure times for flights from Pisa (PSA) to Brussels (BRU) are in the late morning, from 9am to noon. About 83% of passengers prefer this time window. Many major carriers, including Brussels Airlines and Lufthansa, offer flights during this window. This timing is convenient as it allows travelers to enjoy a relaxed morning before their flight.
How long does it take to fly from Pisa (PSA-Galileo Galilei) to Brussels (BRU-Brussels - National)?
Direct flights from PSA to BRU usually take about 1 hour 50 minutes, traveling roughly 569 miles. If you opt for a connecting flight, expect to add around 6 hours 10 minutes to your journey. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Pisa (PSA-Galileo Galilei) to Brussels (BRU-Brussels - National)?
You can fly business class between PSA and BRU. Airlines that offer business class service on this route include:

  • British Airways
  • Air Dolomiti
  • SAS
  • Aegean
  • Air Baltic

How do I earn miles on a Pisa (PSA-Galileo Galilei) to Brussels (BRU-Brussels - National) flight with Expedia?
It's easy to earn miles on a Pisa (PSA-Galileo Galilei) to Brussels (BRU-Brussels - National) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Brussels from Galileo Galilei (PSA)?
From Galileo Galilei (PSA), you can fly into Brussels - National (BRU) to reach Brussels. Some flights may connect through major hubs like Frankfurt Intl. (FRA), Kastrup (CPH), Riga Intl. (RIX) before reaching Brussels. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Pisa (PSA-Galileo Galilei) to Brussels (BRU-Brussels - National) at the last minute?
Typically, booking a last minute flight from Pisa (PSA-Galileo Galilei) to Brussels (BRU-Brussels - National) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Pisa (PSA-Galileo Galilei) to Brussels (BRU-Brussels - National) flight and hotel package?
Securing a Pisa (PSA-Galileo Galilei) to Brussels (BRU-Brussels - National) Brussels Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Pisa (PSA-Galileo Galilei) to Brussels (BRU-Brussels - National)?
If you booked your Pisa (PSA-Galileo Galilei) to Brussels (BRU-Brussels - National) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Galileo Galilei
Destination airport
Brussels - National
Airlines serving
British Airways, KLM, Lufthansa, Scandinavian Airlines
Roundtrip price
$94
Distance
568 mi

Book with confidence

Pisa to Brussels Flights

The cheapest times to fly from Pisa to Brussels

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Pisa to Brussels are during the month of April. You can find some of the cheapest flights from Pisa to Brussels with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Pisa to Brussels

Sunday is one of the best days to book for cheap flights from Pisa to Brussels: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Pisa to Brussels

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Pisa to Brussels in 2026. You can also book with separate airlines for your outbound and return journeys, from $27 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Pisa to Brussels flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Pisa to Brussels airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Pisa to Brussels Flights

*Flight schedules are subject to change.

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*Available to One Key members.