$437 Cheap Flights from Panama City (PTY) to St. John's (ANU)

View $437 flight on Fri, Jan 23, 2026Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to V.C. Bird Intl. Airport (ANU)

Cheap Flights from Panama City to St. John's (PTY-ANU)

Prices were available within the past 7 days and start at $437 for one-way flights and $781 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Fri, Dec 5 - Wed, Dec 10
PTY
Panama City
ANU
Antigua
$781 Roundtrip, found 4 days ago
$781
Roundtrip
found 4 days ago
Select Copa flight, departing Fri, Dec 5 from Panama City to Antigua, returning Wed, Dec 10, priced at $781 found 4 days ago
Copa
Fri, Oct 24 - Thu, Oct 30
PTY
Panama City
ANU
Antigua
$786 Roundtrip, found 1 day ago
$786
Roundtrip
found 1 day ago
Select Copa flight, departing Fri, Oct 24 from Panama City to Antigua, returning Thu, Oct 30, priced at $786 found 1 day ago
Copa
Fri, Oct 24 - Fri, Oct 31
PTY
Panama City
ANU
Antigua
$792 Roundtrip, found 1 day ago
$792
Roundtrip
found 1 day ago
Select Copa flight, departing Fri, Oct 24 from Panama City to Antigua, returning Fri, Oct 31, priced at $792 found 1 day ago
Copa
Wed, Dec 3 - Wed, Dec 10
PTY
Panama City
ANU
Antigua
$796 Roundtrip, found 4 days ago
$796
Roundtrip
found 4 days ago
Select Copa flight, departing Wed, Dec 3 from Panama City to Antigua, returning Wed, Dec 10, priced at $796 found 4 days ago
Copa
Wed, Dec 3 - Fri, Dec 5
PTY
Panama City
ANU
Antigua
$801 Roundtrip, found 4 days ago
$801
Roundtrip
found 4 days ago
Select Copa flight, departing Wed, Dec 3 from Panama City to Antigua, returning Fri, Dec 5, priced at $801 found 4 days ago
Copa
Fri, Nov 7 - Tue, Nov 11
PTY
Panama City
ANU
Antigua
$802 Roundtrip, found 5 days ago
$802
Roundtrip
found 5 days ago
Select Copa flight, departing Fri, Nov 7 from Panama City to Antigua, returning Tue, Nov 11, priced at $802 found 5 days ago
Copa
Fri, Nov 7 - Sat, Nov 8
PTY
Panama City
ANU
Antigua
$813 Roundtrip, found 5 days ago
$813
Roundtrip
found 5 days ago
Select Copa flight, departing Fri, Nov 7 from Panama City to Antigua, returning Sat, Nov 8, priced at $813 found 5 days ago
Copa
Wed, Nov 5 - Tue, Nov 11
PTY
Panama City
ANU
Antigua
$817 Roundtrip, found 5 days ago
$817
Roundtrip
found 5 days ago
Select Copa flight, departing Wed, Nov 5 from Panama City to Antigua, returning Tue, Nov 11, priced at $817 found 5 days ago
Copa
Sat, Nov 8 - Tue, Nov 11
PTY
Panama City
ANU
Antigua
$823 Roundtrip, found 5 days ago
$823
Roundtrip
found 5 days ago
Select Copa flight, departing Sat, Nov 8 from Panama City to Antigua, returning Tue, Nov 11, priced at $823 found 5 days ago
American Airlines
Fri, Oct 10 - Fri, Oct 17
PTY
Panama City
ANU
Antigua
$2,108 Roundtrip, found 14 hours ago
$2,108
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Fri, Oct 10 from Panama City to Antigua, returning Fri, Oct 17, priced at $2,108 found 14 hours ago

Alternative airports near Osbourn

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to V.C. Bird Intl. ANU. Cheapest option available. Flights from $848
ANU
V.C. Bird Intl.
Cheapest
Flights from $848
Flights from Panama City (PTY) to St. John's (ANU)
Origin airport
Tocumen Intl.
Destination airport
V.C. Bird Intl.
Airlines serving
American Airlines
Roundtrip price
$780
Distance
1307 mi

Panama City to St. John's Flights

The cheapest times to fly from Panama City to St. John's

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to St. John's are during the month of December. You can find some of the cheapest flights from Panama City to St. John's with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to St. John's

Sunday is one of the best days to book for cheap flights from Panama City to St. John's: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to St. John's

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to St. John's in 2025. You can also book with separate airlines for your outbound and return journeys, from $437 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to St. John's flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to St. John's airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Tocumen Intl. Airport (PTY) to V.C. Bird Intl. Airport (ANU) cost?
Grab a cheap one-way flight from $437 or cheap return flight from $781 from Tocumen Intl. Airport (PTY) to V.C. Bird Intl. Airport (ANU) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Tocumen Intl. Airport (PTY) to V.C. Bird Intl. Airport (ANU)?
December is the most affordable month to fly from PTY to ANU. Timing your trip outside of the busy season is often the key to scoring lower fares.
What is the cheapest airline that flies from Tocumen Intl. Airport (PTY) to V.C. Bird Intl. Airport (ANU)?
Expedia's filter tool lets you easily compare airlines, flight times and baggage options all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest PTY to ANU flight.
How many flights per day from Tocumen Intl. Airport (PTY) to V.C. Bird Intl. Airport (ANU)?
You'll have to take a flight with a layover if you're traveling from Tocumen Intl. Airport (PTY) to V.C. Bird Intl. Airport (ANU). Direct flights don't operate daily on this route. However, simply filter your search to include one or two stops to discover the best option for your trip.
What day of the week has the most flights from PTY to ANU?
Typically you'll have the most choice when it comes to flights on a Friday. Tuesdays are often the quietest.* However, this can vary depending on the season, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Tocumen Intl. Airport (PTY) to V.C. Bird Intl. Airport (ANU)?
To reach V.C. Bird Intl. Airport (ANU) without delays, select a flight that takes off from Tocumen Intl. Airport (PTY) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Tocumen Intl. Airport (PTY) to V.C. Bird Intl. Airport (ANU) last-minute?
Waiting until right before your break to book a flight from PTY to ANU often results in higher prices. Although you may find some last-minute deals, they aren't always guaranteed. Be flexible with your itinerary for the best chance of scoring a bargain.
Is it cheaper to book a PTY to ANU flight and hotel package?
Compared with arranging flights and hotels separately, booking a PTY to ANU flight and hotel package with Expedia could result in significant savings. Better still, having everything in one convenient place takes the hassle out of travel planning. Simply secure your flights and select from our wide range of hotels, then customize your trip with extras like tours and car rentals.
Can I cancel or change the date of my flight from Tocumen Intl. Airport (PTY) to V.C. Bird Intl. Airport (ANU)?
Typically, you can reschedule or cancel your PTY to ANU flight. However, there may be additional fees, especially if your booking was made more than 24 hours ago. Double-check your itinerary for the airline's fees and rules on flight changes, or if you'd like more information, visit our Customer Service portal.

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*Available to One Key members.