$249 Cheap Flights from Fort Myers (RSW) to Santa Fe (SAF)

View $249 flight on Wed, Feb 25, 2026Opens in a new window

Popular airlines from Southwest Florida Intl. Airport (RSW) to Santa Fe Municipal Airport (SAF)

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Cheap Flights from Fort Myers to Santa Fe (RSW-SAF)

Prices were available within the past 7 days and start at $249 for one-way flights and $294 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Feb 25 - Mon, Mar 2
RSW
Fort Myers
SAF
Santa Fe
$294 Roundtrip, found 2 days ago
$294
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Feb 25 from Fort Myers to Santa Fe, returning Mon, Mar 2, priced at $294 found 2 days ago
American Airlines
Wed, Feb 25 - Mon, Mar 2
RSW
Fort Myers
SAF
Santa Fe
$374 Roundtrip, found 2 days ago
$374
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Feb 25 from Fort Myers to Santa Fe, returning Mon, Mar 2, priced at $374 found 2 days ago
United
Sat, Jan 17 - Tue, Jan 27
RSW
Fort Myers
SAF
Santa Fe
$374 Roundtrip, found 5 hours ago
$374
Roundtrip
found 5 hours ago
Select United flight, departing Sat, Jan 17 from Fort Myers to Santa Fe, returning Tue, Jan 27, priced at $374 found 5 hours ago
American Airlines
Sat, Jan 17 - Wed, Jan 28
RSW
Fort Myers
SAF
Santa Fe
$384 Roundtrip, found 5 hours ago
$384
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Sat, Jan 17 from Fort Myers to Santa Fe, returning Wed, Jan 28, priced at $384 found 5 hours ago
American Airlines
Tue, Apr 21 - Tue, Apr 28
RSW
Fort Myers
SAF
Santa Fe
$385 Roundtrip, found 5 days ago
$385
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Apr 21 from Fort Myers to Santa Fe, returning Tue, Apr 28, priced at $385 found 5 days ago
American Airlines
Thu, Dec 4 - Wed, Dec 17
RSW
Fort Myers
SAF
Santa Fe
$389 Roundtrip, found 5 hours ago
$389
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Thu, Dec 4 from Fort Myers to Santa Fe, returning Wed, Dec 17, priced at $389 found 5 hours ago
American Airlines
Wed, Feb 25 - Mon, Mar 2
RSW
Fort Myers
SAF
Santa Fe
$395 Roundtrip, found 2 days ago
$395
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Feb 25 from Fort Myers to Santa Fe, returning Mon, Mar 2, priced at $395 found 2 days ago
United
Tue, Jan 13 - Fri, Jan 30
RSW
Fort Myers
SAF
Santa Fe
$409 Roundtrip, found 5 hours ago
$409
Roundtrip
found 5 hours ago
Select United flight, departing Tue, Jan 13 from Fort Myers to Santa Fe, returning Fri, Jan 30, priced at $409 found 5 hours ago
American Airlines
Tue, Jan 27 - Tue, Feb 10
RSW
Fort Myers
SAF
Santa Fe
$414 Roundtrip, found 5 hours ago
$414
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Tue, Jan 27 from Fort Myers to Santa Fe, returning Tue, Feb 10, priced at $414 found 5 hours ago
American Airlines
Tue, Apr 21 - Tue, Apr 28
RSW
Fort Myers
SAF
Santa Fe
$415 Roundtrip, found 5 days ago
$415
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Apr 21 from Fort Myers to Santa Fe, returning Tue, Apr 28, priced at $415 found 5 days ago

Alternative airports near Santa Fe

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Santa Fe Municipal SAF. Cheapest and Closest option available. Average driving time to city center is 17 minutes. Flights from $453
SAF
Santa Fe Municipal
CheapestClosest
Average driving time to city center17 min
Flights from $453

Frequently asked questions

How much does a flight from Southwest Florida Intl. Airport (RSW) to Santa Fe Municipal Airport (SAF) cost?
Grab a cheap one-way flight from $249 or cheap return flight from $294 from Southwest Florida Intl. Airport (RSW) to Santa Fe Municipal Airport (SAF) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Southwest Florida Intl. Airport (RSW) to Santa Fe Municipal Airport (SAF)?
February is the cheapest month to fly from RSW to SAF. Traveling outside of peak seasons is often the key to landing a great deal.
What is the cheapest airline that flies from Southwest Florida Intl. Airport (RSW) to Santa Fe Municipal Airport (SAF)?
Use the filters on Expedia to compare airlines and find the cheapest carrier that'll take you from RSW to SAF. Then, sort your results by "Price (lowest to highest)" to pick up the best deal available.
How many flights per day from Southwest Florida Intl. Airport (RSW) to Santa Fe Municipal Airport (SAF)?
Nonstop flights from Southwest Florida Intl. Airport (RSW) to Santa Fe Municipal Airport (SAF) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filters. Enter your travel details and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from RSW to SAF?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can vary depending on various factors, such as the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Southwest Florida Intl. Airport (RSW) to Santa Fe Municipal Airport (SAF)?
To reach Santa Fe Municipal Airport (SAF) on time, select a flight that leaves from Southwest Florida Intl. Airport (RSW) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Southwest Florida Intl. Airport (RSW) to Santa Fe Municipal Airport (SAF) last-minute?
Holding off until right before your break to book a flight from RSW to SAF generally means paying more. While it's possible to find some last-minute deals, they aren't always guaranteed. Keep your travel plans flexible for a better chance of landing a bargain.
Is it cheaper to book a RSW to SAF flight and hotel package?
Opting for a RSW to SAF flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip all in one place. Pick from our wide range of stays and then add activities, car rentals and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Southwest Florida Intl. Airport (RSW) to Santa Fe Municipal Airport (SAF)?
Typically, you're able to cancel or reschedule your RSW to SAF flight. However, additional charges may apply, especially if you booked over 24 hours ago. Double-check your itinerary for the airline's fees and rules on flight changes, or if you want further information, head to our Customer Service portal.

Travel information

Origin airport
Southwest Florida Intl.
Destination airport
Santa Fe Municipal
Airlines serving
American Airlines, United
Roundtrip price
$294
Distance
1565 mi

Book with confidence

Fort Myers to Santa Fe Flights

The cheapest times to fly from Fort Myers to Santa Fe

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Fort Myers to Santa Fe are during the month of February. You can find some of the cheapest flights from Fort Myers to Santa Fe with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Fort Myers to Santa Fe

Sunday is one of the best days to book for cheap flights from Fort Myers to Santa Fe: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Fort Myers to Santa Fe

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Fort Myers to Santa Fe in 2025. You can also book with separate airlines for your outbound and return journeys, from $249 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Fort Myers to Santa Fe flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Fort Myers to Santa Fe airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Fort Myers to Santa Fe Flights

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*Available to One Key members.