$141 Cheap Flights from Santiago (SCL) to Medellín (MDE)

View $141 flight on Tue, Apr 21, 2026Opens in a new window

Popular airlines from Santiago Intl. Airport (SCL) to Jose Maria Cordova Intl. Airport (MDE)

Cheap Flights from Santiago to Medellín (SCL-MDE)

Prices were available within the past 7 days and start at $141 for one-way flights and $293 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Jetsmart SPA
Tue, Mar 17 - Thu, Apr 9
SCL
Santiago
MDE
Medellin
$293 Roundtrip, found 3 days ago
$293
Roundtrip
found 3 days ago
Select Jetsmart SPA flight, departing Tue, Mar 17 from Santiago to Medellin, returning Thu, Apr 9, priced at $293 found 3 days ago
Jetsmart SPA
Fri, Apr 24 - Fri, May 1
SCL
Santiago
MDE
Medellin
$295 Roundtrip, found 1 day ago
$295
Roundtrip
found 1 day ago
Select Jetsmart SPA flight, departing Fri, Apr 24 from Santiago to Medellin, returning Fri, May 1, priced at $295 found 1 day ago
Jetsmart SPA
Tue, Mar 17 - Mon, Mar 23
SCL
Santiago
MDE
Medellin
$299 Roundtrip, found 3 days ago
$299
Roundtrip
found 3 days ago
Select Jetsmart SPA flight, departing Tue, Mar 17 from Santiago to Medellin, returning Mon, Mar 23, priced at $299 found 3 days ago
Jetsmart SPA
Tue, Mar 10 - Thu, Mar 12
SCL
Santiago
MDE
Medellin
$302 Roundtrip, found 3 days ago
$302
Roundtrip
found 3 days ago
Select Jetsmart SPA flight, departing Tue, Mar 10 from Santiago to Medellin, returning Thu, Mar 12, priced at $302 found 3 days ago
Jetsmart SPA
Tue, Apr 21 - Thu, Apr 30
SCL
Santiago
MDE
Medellin
$304 Roundtrip, found 1 day ago
$304
Roundtrip
found 1 day ago
Select Jetsmart SPA flight, departing Tue, Apr 21 from Santiago to Medellin, returning Thu, Apr 30, priced at $304 found 1 day ago
Jetsmart SPA
Tue, Mar 10 - Sun, Mar 29
SCL
Santiago
MDE
Medellin
$308 Roundtrip, found 3 days ago
$308
Roundtrip
found 3 days ago
Select Jetsmart SPA flight, departing Tue, Mar 10 from Santiago to Medellin, returning Sun, Mar 29, priced at $308 found 3 days ago
Jetsmart SPA
Tue, Mar 17 - Sun, Mar 22
SCL
Santiago
MDE
Medellin
$309 Roundtrip, found 3 days ago
$309
Roundtrip
found 3 days ago
Select Jetsmart SPA flight, departing Tue, Mar 17 from Santiago to Medellin, returning Sun, Mar 22, priced at $309 found 3 days ago
LATAM Airlines Group
Fri, Feb 27 - Sat, Mar 7
SCL
Santiago
MDE
Medellin
$369 Roundtrip, found 1 day ago
$369
Roundtrip
found 1 day ago
Select LATAM Airlines Group flight, departing Fri, Feb 27 from Santiago to Medellin, returning Sat, Mar 7, priced at $369 found 1 day ago
Copa
Thu, Nov 20 - Mon, Nov 24
SCL
Santiago
MDE
Medellin
$378 Roundtrip, found 1 hour ago
$378
Roundtrip
found 1 hour ago
Select Copa flight, departing Thu, Nov 20 from Santiago to Medellin, returning Mon, Nov 24, priced at $378 found 1 hour ago
avianca
Thu, Nov 20 - Mon, Nov 24
SCL
Santiago
MDE
Medellin
$401 Roundtrip, found 1 hour ago
$401
Roundtrip
found 1 hour ago
Select avianca flight, departing Thu, Nov 20 from Santiago to Medellin, returning Mon, Nov 24, priced at $401 found 1 hour ago

Find the cheapest month to fly from Santiago (SCL) to Medellín (MDE)

March is typically the cheapest month to fly

From $279 - $460 per traveler.

Alternative airports near Medellín

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Enrique Olaya Herrera EOH. Closest option available. Average driving time to city center is 4 minutes. Flights from $463
EOH
Enrique Olaya Herrera
Closest
Average driving time to city center4 min
Flights from $463

Frequently asked questions

How much does a flight from Arturo Merino Benitez Airport (SCL) to Jose Maria Cordova Intl. Airport (MDE) cost?
Snag a cheap one-way flight from $141 or cheap return flight from $293 from Arturo Merino Benitez Airport (SCL) to Jose Maria Cordova Intl. Airport (MDE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Arturo Merino Benitez Airport (SCL) to Jose Maria Cordova Intl. Airport (MDE)?
March is the most affordable month to fly from SCL to MDE. Traveling outside of peak seasons is often the key to finding a great deal.
Which airlines fly direct from Arturo Merino Benitez Airport (SCL) to Jose Maria Cordova Intl. Airport (MDE)?
Hop on a nonstop flight with AVIANCA and go straight from Arturo Merino Benitez Airport (SCL) to Jose Maria Cordova Intl. Airport (MDE).
What is the cheapest airline that flies from Arturo Merino Benitez Airport (SCL) to Jose Maria Cordova Intl. Airport (MDE)?
While prices may vary depending on when you travel, AVIANCA and JetSMART are often among the top picks for flights between Arturo Merino Benitez Airport (SCL) and Jose Maria Cordova Intl. Airport (MDE). You can also compare carriers on Expedia and use the "Sort by" filter to find the cheapest ticket for your SCL to MDE flight.
How many flights per day from Arturo Merino Benitez Airport (SCL) to Jose Maria Cordova Intl. Airport (MDE)?
On average, Arturo Merino Benitez Airport (SCL) only has 1 direct flight to Jose Maria Cordova Intl. Airport (MDE) every day. To explore more options, try Expedia's easy-to-use filter tool. Simply enter your travel details, then click on "1 Stop" or "2+ Stops" to discover flights offering layovers.
What are the most popular departure times for flights from Arturo Merino Benitez Airport (SCL) to Jose Maria Cordova Intl. Airport (MDE)?
More passengers fly between SCL and MDE at 3 AM than at any other time. Prefer a quieter experience? Pick a flight outside the busiest times and it's possible you'll save on your ticket as well.
What day of the week has the most flights from SCL to MDE?
Travel on a Monday if you're after the largest selection of flights from Arturo Merino Benitez Airport (SCL) to Jose Maria Cordova Intl. Airport (MDE).
What is the earliest flight from Arturo Merino Benitez Airport (SCL) to Jose Maria Cordova Intl. Airport (MDE)?
Catch the earliest flight at around 3:05AM UTC-3, heading out of Arturo Merino Benitez Airport (SCL). You'll be in the air for about 5h 50m, touching down at Jose Maria Cordova Intl. Airport (MDE) at approximately 6:55AM UTC-5.
How long does it take to fly from Arturo Merino Benitez Airport (SCL) to Jose Maria Cordova Intl. Airport (MDE)?
The average flight time from SCL to MDE is 6 hours and 7 minutes, covering a total distance of 2,800 mi.
What airline has the least delays from SCL to MDE?
With 90% of journeys typically landing on time, JetSMART has the best on-time performance for direct flights from Arturo Merino Benitez Airport (SCL) to Jose Maria Cordova Intl. Airport (MDE). To monitor your flight status and get notified if anything changes, simply head to the Expedia App.
What is the best time to fly from Arturo Merino Benitez Airport (SCL) to Jose Maria Cordova Intl. Airport (MDE)?
To land at Jose Maria Cordova Intl. Airport (MDE) without delays, select a flight that leaves from Arturo Merino Benitez Airport (SCL) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Medellin from Arturo Merino Benitez Airport (SCL)?
If you're flying on a direct flight from Arturo Merino Benitez Airport (SCL) to Medellin, Jose Maria Cordova Intl. Airport (MDE) is the only airport you can touch down at.
Is it cheaper to buy a plane ticket from Arturo Merino Benitez Airport (SCL) to Jose Maria Cordova Intl. Airport (MDE) last-minute?
Waiting until right before your break to book a flight from SCL to MDE often results in higher prices. While it's possible to find some last-minute deals, they aren't always guaranteed. Allow some flexibility in your schedule to boost your chances of scoring a bargain.
Is it cheaper to book a SCL to MDE flight and hotel package?
You'll typically save money by securing a SCL to MDE flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. Once you've selected your preferred accommodations and flights, consider other add-ons like car rentals, activities and tours.
Can I cancel or change the date of my flight from Arturo Merino Benitez Airport (SCL) to Jose Maria Cordova Intl. Airport (MDE)?
It's generally possible to reschedule or cancel your SCL to MDE flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
Arturo Merino Benitez
Destination airport
José María Córdova Intl.
Airlines serving
Copa, Jetsmart SPA, LATAM Airlines Group, avianca
Roundtrip price
$293
Distance
2750 mi

Book with confidence

Santiago to Medellín Flights

The cheapest times to fly from Santiago to Medellín

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santiago to Medellín are during the month of March. You can find some of the cheapest flights from Santiago to Medellín with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santiago to Medellín

Sunday is one of the best days to book for cheap flights from Santiago to Medellín: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santiago to Medellín

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santiago to Medellín in 2025. You can also book with separate airlines for your outbound and return journeys, from $141 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santiago to Medellín flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santiago to Medellín airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Santiago to Medellín Flights

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*Available to One Key members.