$500 Cheap Flights from Louisville (SDF) to Cusco (CUZ)

View $500 flight on Sat, Mar 7, 2026Opens in a new window

Popular airlines from Louisville Intl. Airport (SDF) to Alejandro Velasco Astete Intl. Airport (CUZ)

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Cheap Flights from Louisville to Cusco (SDF-CUZ)

Prices were available within the past 7 days and start at $500 for one-way flights and $725 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Tue, Mar 10 - Tue, Mar 17
SDF
Louisville
CUZ
Cusco
$725 Roundtrip, found 2 days ago
$725
Roundtrip
found 2 days ago
Select United flight, departing Tue, Mar 10 from Louisville to Cusco, returning Tue, Mar 17, priced at $725 found 2 days ago
United
Mon, Nov 24 - Wed, Dec 3
SDF
Louisville
CUZ
Cusco
$743 Roundtrip, found 2 days ago
$743
Roundtrip
found 2 days ago
Select United flight, departing Mon, Nov 24 from Louisville to Cusco, returning Wed, Dec 3, priced at $743 found 2 days ago
United
Mon, Mar 9 - Tue, Mar 17
SDF
Louisville
CUZ
Cusco
$762 Roundtrip, found 2 days ago
$762
Roundtrip
found 2 days ago
Select United flight, departing Mon, Mar 9 from Louisville to Cusco, returning Tue, Mar 17, priced at $762 found 2 days ago
United
Sun, Mar 8 - Tue, Mar 17
SDF
Louisville
CUZ
Cusco
$772 Roundtrip, found 2 days ago
$772
Roundtrip
found 2 days ago
Select United flight, departing Sun, Mar 8 from Louisville to Cusco, returning Tue, Mar 17, priced at $772 found 2 days ago
United
Mon, Nov 24 - Tue, Dec 2
SDF
Louisville
CUZ
Cusco
$780 Roundtrip, found 2 days ago
$780
Roundtrip
found 2 days ago
Select United flight, departing Mon, Nov 24 from Louisville to Cusco, returning Tue, Dec 2, priced at $780 found 2 days ago
United
Mon, Mar 9 - Wed, Mar 18
SDF
Louisville
CUZ
Cusco
$799 Roundtrip, found 2 days ago
$799
Roundtrip
found 2 days ago
Select United flight, departing Mon, Mar 9 from Louisville to Cusco, returning Wed, Mar 18, priced at $799 found 2 days ago
United
Sun, Mar 8 - Wed, Mar 18
SDF
Louisville
CUZ
Cusco
$809 Roundtrip, found 2 days ago
$809
Roundtrip
found 2 days ago
Select United flight, departing Sun, Mar 8 from Louisville to Cusco, returning Wed, Mar 18, priced at $809 found 2 days ago
Delta
Wed, Mar 4 - Thu, Mar 19
SDF
Louisville
CUZ
Cusco
$923 Roundtrip, found 2 days ago
$923
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, Mar 4 from Louisville to Cusco, returning Thu, Mar 19, priced at $923 found 2 days ago
LATAM Airlines Group
Thu, Mar 5 - Thu, Mar 19
SDF
Louisville
CUZ
Cusco
$953 Roundtrip, found 2 days ago
$953
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Thu, Mar 5 from Louisville to Cusco, returning Thu, Mar 19, priced at $953 found 2 days ago
American Airlines
Sat, Mar 7 - Mon, Mar 16
SDF
Louisville
CUZ
Cusco
$962 Roundtrip, found 2 days ago
$962
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Mar 7 from Louisville to Cusco, returning Mon, Mar 16, priced at $962 found 2 days ago
Flights from Louisville (SDF) to Cusco (CUZ)
Origin airport
Louisville Intl.
Destination airport
Alejandro Velasco Astete Intl.
Airlines serving
American Airlines, Delta, LATAM Airlines Group
Roundtrip price
$725
Distance
3683 mi

Louisville to Cusco Flights

The cheapest times to fly from Louisville to Cusco

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Louisville to Cusco are during the month of March. You can find some of the cheapest flights from Louisville to Cusco with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Louisville to Cusco

Sunday is one of the best days to book for cheap flights from Louisville to Cusco: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Louisville to Cusco

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Louisville to Cusco in 2025. You can also book with separate airlines for your outbound and return journeys, from $500 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Louisville to Cusco flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Louisville to Cusco airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Louisville Intl. Airport (SDF) to Alejandro Velasco Astete Intl. Airport (CUZ) cost?
Get a cheap one-way flight from $500 or cheap return flight from $725 from Louisville Intl. Airport (SDF) to Alejandro Velasco Astete Intl. Airport (CUZ) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Louisville Intl. Airport (SDF) to Alejandro Velasco Astete Intl. Airport (CUZ)?
The cheapest month to fly from SDF to CUZ is March, when demand is low. Off-peak season is typically when airlines offer lower prices between these airports.
What is the cheapest airline that flies from Louisville Intl. Airport (SDF) to Alejandro Velasco Astete Intl. Airport (CUZ)?
To find the cheapest airline that'll fly you from SDF to CUZ, use Expedia's filter tool. Customize your search based on what matters most to you, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Louisville Intl. Airport (SDF) to Alejandro Velasco Astete Intl. Airport (CUZ)?
Direct flights from Louisville Intl. Airport (SDF) to Alejandro Velasco Astete Intl. Airport (CUZ) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel details and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from SDF to CUZ?
You'll typically find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Louisville Intl. Airport (SDF) to Alejandro Velasco Astete Intl. Airport (CUZ)?
To avoid possible delays on the Louisville Intl. Airport (SDF) to Alejandro Velasco Astete Intl. Airport (CUZ) route, travel before 3 PM. Departures after this hour have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Louisville Intl. Airport (SDF) to Alejandro Velasco Astete Intl. Airport (CUZ) last-minute?
Last-minute fares from SDF to CUZ are generally more expensive. To lock in the best rates, start looking for flights ahead of time. That said, if you can play around with your travel dates, it's possible to land a cheap fare right before your trip.
Is it cheaper to book a SDF to CUZ flight and hotel package?
Securing a SDF to CUZ flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip in one place. Select from our wide range of accommodations and then add flights, car rentals and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Louisville Intl. Airport (SDF) to Alejandro Velasco Astete Intl. Airport (CUZ)?
If you reserved your SDF to CUZ flight in the last 24 hours, you may be able to cancel or modify it at no cost. Depending on the airline and the type of ticket you have, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for more details.

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*Available to One Key members.