$375 Cheap Flights from San Francisco (SFO) to Puerto Maldonado (PEM)

View $375 flight on Wed, Dec 3, 2025Opens in a new window

Popular airlines from San Francisco Intl. Airport (SFO) to Puerto Maldonado (PEM-Padre Aldamiz Intl.)

Cheap Flights from San Francisco to Puerto Maldonado (SFO-PEM)

Prices were available within the past 7 days and start at $375 for one-way flights and $1,194 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Fri, Nov 21 - Tue, Nov 25
SFO
San Francisco
PEM
Puerto Maldonado
$1,194 Roundtrip, found 23 hours ago
$1,194
Roundtrip
found 23 hours ago
Select LATAM Airlines Group flight, departing Fri, Nov 21 from San Francisco to Puerto Maldonado, returning Tue, Nov 25, priced at $1,194 found 23 hours ago
LATAM Airlines Group
Fri, Nov 21 - Tue, Nov 25
SFO
San Francisco
PEM
Puerto Maldonado
$1,219 Roundtrip, found 23 hours ago
$1,219
Roundtrip
found 23 hours ago
Select LATAM Airlines Group flight, departing Fri, Nov 21 from San Francisco to Puerto Maldonado, returning Tue, Nov 25, priced at $1,219 found 23 hours ago
LATAM Airlines Group
Fri, Nov 21 - Tue, Nov 25
SFO
San Francisco
PEM
Puerto Maldonado
$1,236 Roundtrip, found 23 hours ago
$1,236
Roundtrip
found 23 hours ago
Select LATAM Airlines Group flight, departing Fri, Nov 21 from San Francisco to Puerto Maldonado, returning Tue, Nov 25, priced at $1,236 found 23 hours ago
LATAM Airlines Group
Fri, Nov 21 - Tue, Nov 25
SFO
San Francisco
PEM
Puerto Maldonado
$1,242 Roundtrip, found 23 hours ago
$1,242
Roundtrip
found 23 hours ago
Select LATAM Airlines Group flight, departing Fri, Nov 21 from San Francisco to Puerto Maldonado, returning Tue, Nov 25, priced at $1,242 found 23 hours ago
LATAM Airlines Group
Fri, Nov 21 - Tue, Nov 25
SFO
San Francisco
PEM
Puerto Maldonado
$1,261 Roundtrip, found 23 hours ago
$1,261
Roundtrip
found 23 hours ago
Select LATAM Airlines Group flight, departing Fri, Nov 21 from San Francisco to Puerto Maldonado, returning Tue, Nov 25, priced at $1,261 found 23 hours ago
LATAM Airlines Group
Fri, Nov 21 - Tue, Nov 25
SFO
San Francisco
PEM
Puerto Maldonado
$1,268 Roundtrip, found 23 hours ago
$1,268
Roundtrip
found 23 hours ago
Select LATAM Airlines Group flight, departing Fri, Nov 21 from San Francisco to Puerto Maldonado, returning Tue, Nov 25, priced at $1,268 found 23 hours ago
LATAM Airlines Group
Fri, Nov 21 - Tue, Nov 25
SFO
San Francisco
PEM
Puerto Maldonado
$1,374 Roundtrip, found 23 hours ago
$1,374
Roundtrip
found 23 hours ago
Select LATAM Airlines Group flight, departing Fri, Nov 21 from San Francisco to Puerto Maldonado, returning Tue, Nov 25, priced at $1,374 found 23 hours ago
LATAM Airlines Group
Fri, Nov 21 - Tue, Nov 25
SFO
San Francisco
PEM
Puerto Maldonado
$1,401 Roundtrip, found 23 hours ago
$1,401
Roundtrip
found 23 hours ago
Select LATAM Airlines Group flight, departing Fri, Nov 21 from San Francisco to Puerto Maldonado, returning Tue, Nov 25, priced at $1,401 found 23 hours ago
LATAM Airlines Group
Fri, Nov 21 - Tue, Nov 25
SFO
San Francisco
PEM
Puerto Maldonado
$1,416 Roundtrip, found 23 hours ago
$1,416
Roundtrip
found 23 hours ago
Select LATAM Airlines Group flight, departing Fri, Nov 21 from San Francisco to Puerto Maldonado, returning Tue, Nov 25, priced at $1,416 found 23 hours ago
Aeromexico
Fri, Nov 21 - Tue, Nov 25
SFO
San Francisco
PEM
Puerto Maldonado
$1,856 Roundtrip, found 23 hours ago
$1,856
Roundtrip
found 23 hours ago
Select Aeromexico flight, departing Fri, Nov 21 from San Francisco to Puerto Maldonado, returning Tue, Nov 25, priced at $1,856 found 23 hours ago

Frequently asked questions

How much does a flight from San Francisco Intl. Airport (SFO) to Padre Aldamiz Intl. Airport (PEM) cost?
Get a cheap one-way flight from $375 or cheap return flight from $1,194 from San Francisco Intl. Airport (SFO) to Padre Aldamiz Intl. Airport (PEM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from San Francisco Intl. Airport (SFO) to Padre Aldamiz Intl. Airport (PEM)?
The cheapest month to fly from SFO to PEM is November, when there's less demand. Off-peak months are generally when you'll find cheap fares for travel between these airports.
What is the cheapest airline that flies from San Francisco Intl. Airport (SFO) to Padre Aldamiz Intl. Airport (PEM)?
To find the cheapest airline that'll fly you from SFO to PEM, use Expedia's filter tool. Tailor your search based on your travel style, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from San Francisco Intl. Airport (SFO) to Padre Aldamiz Intl. Airport (PEM)?
Direct flights from San Francisco Intl. Airport (SFO) to Padre Aldamiz Intl. Airport (PEM) aren't available daily, so you'll have to take a flight with a layover. Explore your options with our filter tool. Enter your dates and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from SFO to PEM?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from San Francisco Intl. Airport (SFO) to Padre Aldamiz Intl. Airport (PEM)?
Opt for a flight from San Francisco Intl. Airport (SFO) to Padre Aldamiz Intl. Airport (PEM) that takes off before 3 PM to reduce the likelihood of delays. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from San Francisco Intl. Airport (SFO) to Padre Aldamiz Intl. Airport (PEM) last-minute?
Waiting until just before your departure to book your flight from SFO to PEM often results in higher prices. Although you may find some last-minute discounts, they aren't always guaranteed. Be flexible with your travel plans to maximize your chances of getting a bargain.
Is it cheaper to book a SFO to PEM flight and hotel package?
Compared with arranging flights and hotels separately, booking a SFO to PEM flight and hotel package with Expedia could lead to significant savings. What's more, having everything in one place takes the hassle out of planning your trip. Simply secure your flights and choose from our extensive range of stays, then personalize your trip with other add-ons like tours, activities and car rentals.
Can I cancel or change the date of my flight from San Francisco Intl. Airport (SFO) to Padre Aldamiz Intl. Airport (PEM)?
If you booked your SFO to PEM flight within the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the type of fare you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more details.

Travel information

Travel information

Origin airport
San Francisco Intl.
Destination airport
Padre Aldamiz Intl.
Airlines serving
Aeromexico, LATAM Airlines Group
Roundtrip price
$1,193
Distance
4885 mi

Book with confidence

Book with confidence

San Francisco to Puerto Maldonado Flights

The cheapest times to fly from San Francisco to Puerto Maldonado

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from San Francisco to Puerto Maldonado are during the month of November. You can find some of the cheapest flights from San Francisco to Puerto Maldonado with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from San Francisco to Puerto Maldonado

Sunday is one of the best days to book for cheap flights from San Francisco to Puerto Maldonado: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from San Francisco to Puerto Maldonado

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from San Francisco to Puerto Maldonado in 2025. You can also book with separate airlines for your outbound and return journeys, from $375 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap San Francisco to Puerto Maldonado flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your San Francisco to Puerto Maldonado airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

San Francisco to Puerto Maldonado Flights

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*Available to One Key members.