$604 Cheap Flights from St. Louis (STL) to Mexicali (MXL)

View $604 flight on Mon, Nov 10, 2025Opens in a new window

Popular airlines from St. Louis Lambert Intl. Airport (STL) to Mexicali, Baja California Norte (MXL-General Rodolfo Sanchez Taboada Intl.)

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Cheap Flights from St. Louis to Mexicali (STL-MXL)

Prices were available within the past 7 days and start at $604 for one-way flights and $2,475 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Mon, Nov 24 - Mon, Dec 1
STL
St. Louis
MXL
Mexicali
$2,475 Roundtrip, found 16 hours ago
$2,475
Roundtrip
found 16 hours ago
Select Aeromexico flight, departing Mon, Nov 24 from St. Louis to Mexicali, returning Mon, Dec 1, priced at $2,475 found 16 hours ago
Aeromexico
Mon, Nov 24 - Mon, Dec 1
STL
St. Louis
MXL
Mexicali
$2,499 Roundtrip, found 3 days ago
$2,499
Roundtrip
found 3 days ago
Select Aeromexico flight, departing Mon, Nov 24 from St. Louis to Mexicali, returning Mon, Dec 1, priced at $2,499 found 3 days ago
Aeromexico
Mon, Nov 24 - Mon, Dec 1
STL
St. Louis
MXL
Mexicali
$2,512 Roundtrip, found 3 days ago
$2,512
Roundtrip
found 3 days ago
Select Aeromexico flight, departing Mon, Nov 24 from St. Louis to Mexicali, returning Mon, Dec 1, priced at $2,512 found 3 days ago
Aeromexico
Mon, Nov 24 - Mon, Dec 1
STL
St. Louis
MXL
Mexicali
$2,560 Roundtrip, found 3 days ago
$2,560
Roundtrip
found 3 days ago
Select Aeromexico flight, departing Mon, Nov 24 from St. Louis to Mexicali, returning Mon, Dec 1, priced at $2,560 found 3 days ago
Aeromexico
Mon, Nov 24 - Mon, Dec 1
STL
St. Louis
MXL
Mexicali
$2,573 Roundtrip, found 3 days ago
$2,573
Roundtrip
found 3 days ago
Select Aeromexico flight, departing Mon, Nov 24 from St. Louis to Mexicali, returning Mon, Dec 1, priced at $2,573 found 3 days ago
Aeromexico
Mon, Nov 24 - Mon, Dec 1
STL
St. Louis
MXL
Mexicali
$2,642 Roundtrip, found 16 hours ago
$2,642
Roundtrip
found 16 hours ago
Select Aeromexico flight, departing Mon, Nov 24 from St. Louis to Mexicali, returning Mon, Dec 1, priced at $2,642 found 16 hours ago
Aeromexico
Mon, Nov 24 - Mon, Dec 1
STL
St. Louis
MXL
Mexicali
$2,703 Roundtrip, found 3 days ago
$2,703
Roundtrip
found 3 days ago
Select Aeromexico flight, departing Mon, Nov 24 from St. Louis to Mexicali, returning Mon, Dec 1, priced at $2,703 found 3 days ago
Aeromexico
Mon, Nov 24 - Mon, Dec 1
STL
St. Louis
MXL
Mexicali
$2,809 Roundtrip, found 16 hours ago
$2,809
Roundtrip
found 16 hours ago
Select Aeromexico flight, departing Mon, Nov 24 from St. Louis to Mexicali, returning Mon, Dec 1, priced at $2,809 found 16 hours ago
Aeromexico
Mon, Nov 24 - Mon, Dec 1
STL
St. Louis
MXL
Mexicali
$2,851 Roundtrip, found 3 days ago
$2,851
Roundtrip
found 3 days ago
Select Aeromexico flight, departing Mon, Nov 24 from St. Louis to Mexicali, returning Mon, Dec 1, priced at $2,851 found 3 days ago
Aeromexico
Mon, Nov 24 - Mon, Dec 1
STL
St. Louis
MXL
Mexicali
$2,870 Roundtrip, found 3 days ago
$2,870
Roundtrip
found 3 days ago
Select Aeromexico flight, departing Mon, Nov 24 from St. Louis to Mexicali, returning Mon, Dec 1, priced at $2,870 found 3 days ago

Frequently asked questions

How much does a flight from Lambert-St. Louis Intl. Airport (STL) to General Rodolfo Sanchez Taboada Intl. Airport (MXL) cost?
Snag a cheap one-way flight from $604 or cheap return flight from $2,475 from Lambert-St. Louis Intl. Airport (STL) to General Rodolfo Sanchez Taboada Intl. Airport (MXL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Lambert-St. Louis Intl. Airport (STL) to General Rodolfo Sanchez Taboada Intl. Airport (MXL)?
November is the most affordable month to fly from STL to MXL. Traveling during an off-peak travel window is often the key to scoring lower fares.
What is the cheapest airline that flies from Lambert-St. Louis Intl. Airport (STL) to General Rodolfo Sanchez Taboada Intl. Airport (MXL)?
To find the cheapest airline flying from STL to MXL, use Expedia's filter tool. Tailor your search based on your travel needs, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Lambert-St. Louis Intl. Airport (STL) to General Rodolfo Sanchez Taboada Intl. Airport (MXL)?
You'll need to hop on a flight with a layover when traveling from Lambert-St. Louis Intl. Airport (STL) to General Rodolfo Sanchez Taboada Intl. Airport (MXL). Direct flights don't operate daily on this route. However, just filter your search to include one or more stops to discover the best option for your trip.
What day of the week has the most flights from STL to MXL?
Usually you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* However, this can change depending on the season, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Lambert-St. Louis Intl. Airport (STL) to General Rodolfo Sanchez Taboada Intl. Airport (MXL)?
To avoid possible delays on the Lambert-St. Louis Intl. Airport (STL) to General Rodolfo Sanchez Taboada Intl. Airport (MXL) route, travel before 3 PM. Departures after this time have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Lambert-St. Louis Intl. Airport (STL) to General Rodolfo Sanchez Taboada Intl. Airport (MXL) last-minute?
Waiting until right before your break to book a flight from STL to MXL often results in higher prices. While you may find some last-minute offers, they aren't always guaranteed. Keep your travel plans flexible for a better chance of snagging a bargain.
Is it cheaper to book a STL to MXL flight and hotel package?
Compared with arranging flights and hotels separately, booking a STL to MXL flight and hotel package with Expedia could result in significant savings. Better still, having everything in one place takes the hassle out of travel planning. Simply secure your flights and select from our extensive range of stays, then tailor your trip with other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from Lambert-St. Louis Intl. Airport (STL) to General Rodolfo Sanchez Taboada Intl. Airport (MXL)?
You can usually reschedule or cancel your STL to MXL flight. However, if it's been more than 24 hours since booking, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
Lambert-St. Louis Intl.
Destination airport
General Rodolfo Sanchez Taboada Intl.
Roundtrip price
$2,475
Distance
1453 mi

Book with confidence

St. Louis to Mexicali Flights

The cheapest times to fly from St. Louis to Mexicali

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Louis to Mexicali are during the month of November. You can find some of the cheapest flights from St. Louis to Mexicali with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from St. Louis to Mexicali

Sunday is one of the best days to book for cheap flights from St. Louis to Mexicali: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from St. Louis to Mexicali

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Louis to Mexicali in 2025. You can also book with separate airlines for your outbound and return journeys, from $604 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap St. Louis to Mexicali flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your St. Louis to Mexicali airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

St. Louis to Mexicali Flights

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*Available to One Key members.