$499 Cheap Flights from St. Louis (STL) to Southampton (SOU)

View $499 flight on Sat, Nov 22, 2025Opens in a new window

Popular airlines from St. Louis Lambert Intl. Airport (STL) to Southampton (SOU)

Cheap Flights from St. Louis to Southampton (STL-SOU)

Prices were available within the past 7 days and start at $499 for one-way flights and $789 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Oct 21 - Thu, Oct 23
STL
St. Louis
SOU
Southampton
$789 Roundtrip, found 4 days ago
$789
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Oct 21 from St. Louis to Southampton, returning Thu, Oct 23, priced at $789 found 4 days ago
Virgin Atlantic
Mon, Nov 17 - Mon, Nov 24
STL
St. Louis
SOU
Southampton
$807 Roundtrip, found 17 hours ago
$807
Roundtrip
found 17 hours ago
Select Virgin Atlantic flight, departing Mon, Nov 17 from St. Louis to Southampton, returning Mon, Nov 24, priced at $807 found 17 hours ago
Virgin Atlantic
Mon, Nov 17 - Mon, Nov 24
STL
St. Louis
SOU
Southampton
$813 Roundtrip, found 17 hours ago
$813
Roundtrip
found 17 hours ago
Select Virgin Atlantic flight, departing Mon, Nov 17 from St. Louis to Southampton, returning Mon, Nov 24, priced at $813 found 17 hours ago
Delta
Mon, Oct 27 - Wed, Oct 29
STL
St. Louis
SOU
Southampton
$822 Roundtrip, found 4 days ago
$822
Roundtrip
found 4 days ago
Select Delta flight, departing Mon, Oct 27 from St. Louis to Southampton, returning Wed, Oct 29, priced at $822 found 4 days ago
KLM
Wed, Oct 22 - Fri, Oct 24
STL
St. Louis
SOU
Southampton
$841 Roundtrip, found 4 days ago
$841
Roundtrip
found 4 days ago
Select KLM flight, departing Wed, Oct 22 from St. Louis to Southampton, returning Fri, Oct 24, priced at $841 found 4 days ago
Delta
Tue, Oct 21 - Fri, Oct 24
STL
St. Louis
SOU
Southampton
$844 Roundtrip, found 4 days ago
$844
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Oct 21 from St. Louis to Southampton, returning Fri, Oct 24, priced at $844 found 4 days ago
KLM
Sat, Oct 25 - Mon, Oct 27
STL
St. Louis
SOU
Southampton
$847 Roundtrip, found 4 days ago
$847
Roundtrip
found 4 days ago
Select KLM flight, departing Sat, Oct 25 from St. Louis to Southampton, returning Mon, Oct 27, priced at $847 found 4 days ago
Delta
Tue, Oct 21 - Mon, Oct 27
STL
St. Louis
SOU
Southampton
$870 Roundtrip, found 4 days ago
$870
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Oct 21 from St. Louis to Southampton, returning Mon, Oct 27, priced at $870 found 4 days ago
Aer Lingus
Mon, Nov 17 - Mon, Nov 24
STL
St. Louis
SOU
Southampton
$995 Roundtrip, found 17 hours ago
$995
Roundtrip
found 17 hours ago
Select Aer Lingus flight, departing Mon, Nov 17 from St. Louis to Southampton, returning Mon, Nov 24, priced at $995 found 17 hours ago
Iberia
Mon, Nov 17 - Mon, Nov 24
STL
St. Louis
SOU
Southampton
$1,004 Roundtrip, found 17 hours ago
$1,004
Roundtrip
found 17 hours ago
Select Iberia flight, departing Mon, Nov 17 from St. Louis to Southampton, returning Mon, Nov 24, priced at $1,004 found 17 hours ago

Frequently asked questions

How much does a flight from Lambert-St. Louis Intl. Airport (STL) to Southampton Airport (SOU) cost?
Snag a cheap one-way flight from $499 or cheap return flight from $789 from Lambert-St. Louis Intl. Airport (STL) to Southampton Airport (SOU) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Lambert-St. Louis Intl. Airport (STL) to Southampton Airport (SOU)?
Planning your getaway for October is a great way to save, as it's the cheapest month for flights between STL and SOU. You'll usually find the lowest prices during the off-season.
What is the cheapest airline that flies from Lambert-St. Louis Intl. Airport (STL) to Southampton Airport (SOU)?
Expedia's filter tool lets you easily compare different airlines, departure times and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest STL to SOU flight.
How many flights per day from Lambert-St. Louis Intl. Airport (STL) to Southampton Airport (SOU)?
You'll have to hop on a flight with a layover if you're traveling from Lambert-St. Louis Intl. Airport (STL) to Southampton Airport (SOU). Direct flights don't operate daily on this route. However, simply filter your search to include one or two stops to find an option that works for you.
What day of the week has the most flights from STL to SOU?
Usually you'll have the most choice when it comes to flights on a Friday. Tuesdays tend to be the quietest.* But this can vary based on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Lambert-St. Louis Intl. Airport (STL) to Southampton Airport (SOU)?
Opt for a flight from Lambert-St. Louis Intl. Airport (STL) to Southampton Airport (SOU) that takes off before 3 PM to reduce the likelihood of delays and cancellations. Later departures have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Lambert-St. Louis Intl. Airport (STL) to Southampton Airport (SOU) last-minute?
Last-minute bookings from STL to SOU are typically more expensive. To lock in the best rates, start searching for flights well in advance. That being said, if you're flexible with your travel dates, you may find a cheap fare right before you leave.
Is it cheaper to book a STL to SOU flight and hotel package?
Compared with arranging hotels and flights separately, booking a STL to SOU flight and hotel package with Expedia could lead to significant savings. Better yet, having everything in one convenient place takes the hassle out of planning your trip. Simply secure your flights and select from our wide range of hotels, then tailor your trip with other add-ons like tours, activities and car rentals.
Can I cancel or change the date of my flight from Lambert-St. Louis Intl. Airport (STL) to Southampton Airport (SOU)?
In most instances, you're able to reschedule or cancel your STL to SOU flight. However, there may be additional charges, especially if you booked over 24 hours ago. Double-check your itinerary for the airline's fees and policies on flight changes, or if you'd like more details, go to our Customer Service portal.

Travel information

Travel information

Origin airport
Lambert-St. Louis Intl.
Destination airport
Southampton
Airlines serving
Aer Lingus, Virgin Atlantic
Roundtrip price
$789
Distance
4170 mi

Book with confidence

Book with confidence

St. Louis to Southampton Flights

The cheapest times to fly from St. Louis to Southampton

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Louis to Southampton are during the month of October. You can find some of the cheapest flights from St. Louis to Southampton with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from St. Louis to Southampton

Sunday is one of the best days to book for cheap flights from St. Louis to Southampton: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from St. Louis to Southampton

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Louis to Southampton in 2025. You can also book with separate airlines for your outbound and return journeys, from $499 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap St. Louis to Southampton flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your St. Louis to Southampton airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

St. Louis to Southampton Flights

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*Available to One Key members.