$192 Cheap Flights from Syracuse (SYR) to Louisville (SDF)

View $192 flight on Tue, Jan 13, 2026Opens in a new window

Popular airlines from Hancock Intl. Airport (SYR) to Louisville Intl. Airport (SDF)

Cheap Flights from Syracuse to Louisville (SYR-SDF)

Prices were available within the past 7 days and start at $192 for one-way flights and $249 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Jan 13 - Tue, Jan 20
SYR
Syracuse
SDF
Louisville
$249 Roundtrip, just found
$249
Roundtrip
just found
Select American Airlines flight, departing Tue, Jan 13 from Syracuse to Louisville, returning Tue, Jan 20, priced at $249 just found
Delta
Tue, Jan 13 - Tue, Jan 20
SYR
Syracuse
SDF
Louisville
$249 Roundtrip, just found
$249
Roundtrip
just found
Select Delta flight, departing Tue, Jan 13 from Syracuse to Louisville, returning Tue, Jan 20, priced at $249 just found
United
Tue, Jan 13 - Tue, Jan 20
SYR
Syracuse
SDF
Louisville
$249 Roundtrip, just found
$249
Roundtrip
just found
Select United flight, departing Tue, Jan 13 from Syracuse to Louisville, returning Tue, Jan 20, priced at $249 just found
United
Tue, Jan 13 - Tue, Jan 20
SYR
Syracuse
SDF
Louisville
$254 Roundtrip, just found
$254
Roundtrip
just found
Select United flight, departing Tue, Jan 13 from Syracuse to Louisville, returning Tue, Jan 20, priced at $254 just found
United
Fri, Jan 30 - Mon, Feb 2
SYR
Syracuse
SDF
Louisville
$259 Roundtrip, found 5 days ago
$259
Roundtrip
found 5 days ago
Select United flight, departing Fri, Jan 30 from Syracuse to Louisville, returning Mon, Feb 2, priced at $259 found 5 days ago
United
Fri, Jan 30 - Mon, Feb 2
SYR
Syracuse
SDF
Louisville
$259 Roundtrip, found 5 days ago
$259
Roundtrip
found 5 days ago
Select United flight, departing Fri, Jan 30 from Syracuse to Louisville, returning Mon, Feb 2, priced at $259 found 5 days ago
United
Tue, Jan 13 - Tue, Jan 20
SYR
Syracuse
SDF
Louisville
$264 Roundtrip, just found
$264
Roundtrip
just found
Select United flight, departing Tue, Jan 13 from Syracuse to Louisville, returning Tue, Jan 20, priced at $264 just found
United
Fri, Jan 30 - Mon, Feb 2
SYR
Syracuse
SDF
Louisville
$264 Roundtrip, found 5 days ago
$264
Roundtrip
found 5 days ago
Select United flight, departing Fri, Jan 30 from Syracuse to Louisville, returning Mon, Feb 2, priced at $264 found 5 days ago
United
Tue, Jan 13 - Tue, Jan 20
SYR
Syracuse
SDF
Louisville
$269 Roundtrip, just found
$269
Roundtrip
just found
Select United flight, departing Tue, Jan 13 from Syracuse to Louisville, returning Tue, Jan 20, priced at $269 just found
American Airlines
Tue, Jan 13 - Tue, Jan 20
SYR
Syracuse
SDF
Louisville
$272 Roundtrip, just found
$272
Roundtrip
just found
Select American Airlines flight, departing Tue, Jan 13 from Syracuse to Louisville, returning Tue, Jan 20, priced at $272 just found

Find the cheapest month to fly from Syracuse (SYR) to Louisville (SDF)

May is typically the cheapest month to fly

From $198 - $506 per traveler.

Alternative airports near Louisville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Louisville Intl. SDF. Cheapest and Closest option available. Average driving time to city center is 9 minutes. Flights from $279
SDF
Louisville Intl.
CheapestClosest
Average driving time to city center9 min
Flights from $279

Frequently asked questions

How much does a flight from Hancock Intl. Airport (SYR) to Louisville Intl. Airport (SDF) cost?
Get a cheap one-way flight from $192 or cheap return flight from $249 from Hancock Intl. Airport (SYR) to Louisville Intl. Airport (SDF) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Hancock Intl. Airport (SYR) to Louisville Intl. Airport (SDF)?
Flying in January is a great way to save, as it's the cheapest month for flights between SYR and SDF. You'll typically find the lowest fares during off-peak months.
What is the cheapest airline that flies from Hancock Intl. Airport (SYR) to Louisville Intl. Airport (SDF)?
Expedia's filter tool lets you easily compare different airlines, travel time and fares all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest SYR to SDF flight.
How many flights per day from Hancock Intl. Airport (SYR) to Louisville Intl. Airport (SDF)?
Direct flights from Hancock Intl. Airport (SYR) to Louisville Intl. Airport (SDF) aren't available daily, so you'll have to take a flight with a layover. Explore your options with our filter tool. Enter your travel details and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from SYR to SDF?
You'll typically find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Hancock Intl. Airport (SYR) to Louisville Intl. Airport (SDF)?
To touch down at Louisville Intl. Airport (SDF) on schedule, book a flight that takes off from Hancock Intl. Airport (SYR) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Hancock Intl. Airport (SYR) to Louisville Intl. Airport (SDF) last-minute?
Booking your flight from SYR to SDF shortly before your journey is usually more expensive. However, if you're flexible with your departure dates and times, you could grab a cheap last-minute fare.
Is it cheaper to book a SYR to SDF flight and hotel package?
Compared with arranging hotels and flights separately, booking a SYR to SDF flight and hotel package with Expedia could lead to significant savings. Better yet, having it all in one place will take the stress out of travel planning. Just secure your flights and choose from our wide range of hotels, then customize your trip with other add-ons like activities and car rentals.
Can I cancel or change the date of my flight from Hancock Intl. Airport (SYR) to Louisville Intl. Airport (SDF)?
Usually, it's possible to cancel or reschedule your SYR to SDF flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
Hancock Intl.
Destination airport
Louisville Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$248
Distance
608 mi

Book with confidence

Syracuse to Louisville Flights

The cheapest times to fly from Syracuse to Louisville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Syracuse to Louisville are during the month of January. You can find some of the cheapest flights from Syracuse to Louisville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Syracuse to Louisville

Sunday is one of the best days to book for cheap flights from Syracuse to Louisville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Syracuse to Louisville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Syracuse to Louisville in 2025. You can also book with separate airlines for your outbound and return journeys, from $192 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Syracuse to Louisville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Syracuse to Louisville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Syracuse to Louisville Flights

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*Available to One Key members.