$244 Cheap Flights from Tampa (TPA) to Sao Luis (SLZ)

View $244 flight on Fri, Oct 24, 2025Opens in a new window

Popular airlines from Tampa Intl. Airport (TPA) to Sao Luis (SLZ-Marechal Cunha Machado Intl.)

Cheap Flights from Tampa to Sao Luis (TPA-SLZ)

Prices were available within the past 7 days and start at $244 for one-way flights and $606 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Mon, Mar 23 - Wed, Apr 8
TPA
Tampa
SLZ
São Luís
$606 Roundtrip, found 4 days ago
$606
Roundtrip
found 4 days ago
Select United flight, departing Mon, Mar 23 from Tampa to São Luís, returning Wed, Apr 8, priced at $606 found 4 days ago
United
Tue, Mar 10 - Sat, Mar 14
TPA
Tampa
SLZ
São Luís
$675 Roundtrip, found 3 days ago
$675
Roundtrip
found 3 days ago
Select United flight, departing Tue, Mar 10 from Tampa to São Luís, returning Sat, Mar 14, priced at $675 found 3 days ago
GOL Linhas Aereas S.A.
Wed, Mar 25 - Fri, Mar 27
TPA
Tampa
SLZ
São Luís
$676 Roundtrip, found 4 days ago
$676
Roundtrip
found 4 days ago
Select GOL Linhas Aereas S.A. flight, departing Wed, Mar 25 from Tampa to São Luís, returning Fri, Mar 27, priced at $676 found 4 days ago
GOL Linhas Aereas S.A.
Tue, Mar 10 - Fri, Mar 27
TPA
Tampa
SLZ
São Luís
$679 Roundtrip, found 3 days ago
$679
Roundtrip
found 3 days ago
Select GOL Linhas Aereas S.A. flight, departing Tue, Mar 10 from Tampa to São Luís, returning Fri, Mar 27, priced at $679 found 3 days ago
GOL Linhas Aereas S.A.
Tue, Mar 24 - Mon, Mar 30
TPA
Tampa
SLZ
São Luís
$685 Roundtrip, found 4 days ago
$685
Roundtrip
found 4 days ago
Select GOL Linhas Aereas S.A. flight, departing Tue, Mar 24 from Tampa to São Luís, returning Mon, Mar 30, priced at $685 found 4 days ago
LATAM Airlines Group
Fri, Oct 24 - Sun, Nov 2
TPA
Tampa
SLZ
São Luís
$695 Roundtrip, found 13 hours ago
$695
Roundtrip
found 13 hours ago
Select LATAM Airlines Group flight, departing Fri, Oct 24 from Tampa to São Luís, returning Sun, Nov 2, priced at $695 found 13 hours ago
GOL Linhas Aereas S.A.
Tue, Mar 10 - Tue, Mar 17
TPA
Tampa
SLZ
São Luís
$722 Roundtrip, found 3 days ago
$722
Roundtrip
found 3 days ago
Select GOL Linhas Aereas S.A. flight, departing Tue, Mar 10 from Tampa to São Luís, returning Tue, Mar 17, priced at $722 found 3 days ago
United
Wed, Mar 11 - Sun, Mar 22
TPA
Tampa
SLZ
São Luís
$728 Roundtrip, found 3 days ago
$728
Roundtrip
found 3 days ago
Select United flight, departing Wed, Mar 11 from Tampa to São Luís, returning Sun, Mar 22, priced at $728 found 3 days ago
American Airlines
Mon, Mar 23 - Tue, Mar 24
TPA
Tampa
SLZ
São Luís
$753 Roundtrip, found 4 days ago
$753
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, Mar 23 from Tampa to São Luís, returning Tue, Mar 24, priced at $753 found 4 days ago
avianca
Fri, Mar 13 - Sun, Mar 22
TPA
Tampa
SLZ
São Luís
$788 Roundtrip, found 4 days ago
$788
Roundtrip
found 4 days ago
Select avianca flight, departing Fri, Mar 13 from Tampa to São Luís, returning Sun, Mar 22, priced at $788 found 4 days ago

Frequently asked questions

How much does a flight from Tampa Intl. Airport (TPA) to Marechal Cunha Machado Intl. Airport (SLZ) cost?
Snag a cheap one-way flight from $244 or cheap return flight from $606 from Tampa Intl. Airport (TPA) to Marechal Cunha Machado Intl. Airport (SLZ) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Tampa Intl. Airport (TPA) to Marechal Cunha Machado Intl. Airport (SLZ)?
The cheapest month to fly from TPA to SLZ is March, when demand is low. Off-peak months are often when airlines offer better prices between these airports.
What is the cheapest airline that flies from Tampa Intl. Airport (TPA) to Marechal Cunha Machado Intl. Airport (SLZ)?
Use the filter tool on Expedia to compare different airlines and find the cheapest carrier that'll fly you from TPA to SLZ. Then, sort your results by "Price (lowest to highest)" to score a great deal.
How many flights per day from Tampa Intl. Airport (TPA) to Marechal Cunha Machado Intl. Airport (SLZ)?
You'll need to catch a flight with a layover when traveling from Tampa Intl. Airport (TPA) to Marechal Cunha Machado Intl. Airport (SLZ). There are no daily direct flights on this route. However, simply filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from TPA to SLZ?
Generally you'll find the widest variety of flight choices on a Friday. Tuesdays are often the quietest.* However, this can vary depending on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Tampa Intl. Airport (TPA) to Marechal Cunha Machado Intl. Airport (SLZ)?
To land at Marechal Cunha Machado Intl. Airport (SLZ) on schedule, pick a flight that leaves from Tampa Intl. Airport (TPA) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Tampa Intl. Airport (TPA) to Marechal Cunha Machado Intl. Airport (SLZ) last-minute?
Last-minute bookings from TPA to SLZ are generally more expensive. For the best rates, start searching for flights well in advance. That said, if you can play around with your travel dates, you may find a cheap ticket right before your trip.
Is it cheaper to book a TPA to SLZ flight and hotel package?
Securing a TPA to SLZ flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip in one place. Pick from our extensive range of accommodations and then add flights, car rentals and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Tampa Intl. Airport (TPA) to Marechal Cunha Machado Intl. Airport (SLZ)?
In most instances, you're able to reschedule or cancel your TPA to SLZ flight. However, additional charges may apply, especially if you made your booking more than 24 hours ago. Check your itinerary for the airline's guidelines and fees on flight changes, or if you'd like further details, head to our Customer Service portal.

Travel information

Origin airport
Tampa Intl.
Destination airport
Marechal Cunha Machado Intl.
Airlines serving
Delta, GOL Linhas Aereas S.A., LATAM Airlines Group
Roundtrip price
$605
Distance
3305 mi

Book with confidence

Tampa to Sao Luis Flights

The cheapest times to fly from Tampa to Sao Luis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Tampa to Sao Luis are during the month of March. You can find some of the cheapest flights from Tampa to Sao Luis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Tampa to Sao Luis

Sunday is one of the best days to book for cheap flights from Tampa to Sao Luis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Tampa to Sao Luis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Tampa to Sao Luis in 2025. You can also book with separate airlines for your outbound and return journeys, from $244 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Tampa to Sao Luis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Tampa to Sao Luis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Tampa to Sao Luis Flights

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*Available to One Key members.