$102 Cheap Flights from Knoxville (TYS) to Charleston (CHS)

View $102 flight on Wed, Dec 10, 2025Opens in a new window

Popular airlines from McGhee Tyson Airport (TYS) to Charleston Intl. Airport (CHS)

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Cheap Flights from Knoxville to Charleston (TYS-CHS)

Prices were available within the past 7 days and start at $102 for one-way flights and $203 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Dec 16 - Wed, Dec 17
TYS
Knoxville
CHS
Charleston
$203 Roundtrip, found 1 day ago
$203
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Dec 16 from Knoxville to Charleston, returning Wed, Dec 17, priced at $203 found 1 day ago
Delta
Thu, Dec 4 - Tue, Dec 16
TYS
Knoxville
CHS
Charleston
$216 Roundtrip, found 11 hours ago
$216
Roundtrip
found 11 hours ago
Select Delta flight, departing Thu, Dec 4 from Knoxville to Charleston, returning Tue, Dec 16, priced at $216 found 11 hours ago
Delta
Thu, Dec 4 - Mon, Dec 15
TYS
Knoxville
CHS
Charleston
$229 Roundtrip, found 11 hours ago
$229
Roundtrip
found 11 hours ago
Select Delta flight, departing Thu, Dec 4 from Knoxville to Charleston, returning Mon, Dec 15, priced at $229 found 11 hours ago
Delta
Fri, Dec 5 - Tue, Dec 16
TYS
Knoxville
CHS
Charleston
$242 Roundtrip, found 11 hours ago
$242
Roundtrip
found 11 hours ago
Select Delta flight, departing Fri, Dec 5 from Knoxville to Charleston, returning Tue, Dec 16, priced at $242 found 11 hours ago
Delta
Fri, Dec 5 - Mon, Dec 15
TYS
Knoxville
CHS
Charleston
$255 Roundtrip, found 11 hours ago
$255
Roundtrip
found 11 hours ago
Select Delta flight, departing Fri, Dec 5 from Knoxville to Charleston, returning Mon, Dec 15, priced at $255 found 11 hours ago
American Airlines
Sat, Dec 13 - Wed, Dec 31
TYS
Knoxville
CHS
Charleston
$263 Roundtrip, found 11 hours ago
$263
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Sat, Dec 13 from Knoxville to Charleston, returning Wed, Dec 31, priced at $263 found 11 hours ago
Delta
Tue, Dec 16 - Fri, Jan 2
TYS
Knoxville
CHS
Charleston
$265 Roundtrip, found 11 hours ago
$265
Roundtrip
found 11 hours ago
Select Delta flight, departing Tue, Dec 16 from Knoxville to Charleston, returning Fri, Jan 2, priced at $265 found 11 hours ago
Delta
Wed, Dec 3 - Mon, Dec 15
TYS
Knoxville
CHS
Charleston
$268 Roundtrip, found 11 hours ago
$268
Roundtrip
found 11 hours ago
Select Delta flight, departing Wed, Dec 3 from Knoxville to Charleston, returning Mon, Dec 15, priced at $268 found 11 hours ago
Southwest Airlines
Wed, Apr 8 - Wed, Apr 15
TYS
Knoxville
CHS
Charleston
$307 Roundtrip, found 6 days ago
$307
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Wed, Apr 8 from Knoxville to Charleston, returning Wed, Apr 15, priced at $307 found 6 days ago
United
Mon, Jan 19 - Fri, Jan 23
TYS
Knoxville
CHS
Charleston
$487 Roundtrip, found 5 days ago
$487
Roundtrip
found 5 days ago
Select United flight, departing Mon, Jan 19 from Knoxville to Charleston, returning Fri, Jan 23, priced at $487 found 5 days ago

Find the cheapest month to fly from Knoxville (TYS) to Charleston (CHS)

May is typically the cheapest month to fly

From $286 - $508 per traveler.

Alternative airports near Charleston

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Charleston Intl. CHS. Cheapest and Closest option available. Average driving time to city center is 16 minutes. Flights from $383
CHS
Charleston Intl.
CheapestClosest
Average driving time to city center16 min
Flights from $383

Frequently asked questions

How much does a flight from McGhee Tyson Airport (TYS) to Charleston Intl. Airport (CHS) cost?
Get a cheap one-way flight from $102 or cheap return flight from $203 from McGhee Tyson Airport (TYS) to Charleston Intl. Airport (CHS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from McGhee Tyson Airport (TYS) to Charleston Intl. Airport (CHS)?
The cheapest month to fly from TYS to CHS is December, when demand is low. Off-peak months are typically when you'll find cheap fares for travel between these airports.
What is the cheapest airline that flies from McGhee Tyson Airport (TYS) to Charleston Intl. Airport (CHS)?
Expedia's filter tool lets you easily compare airlines, flight times and fares all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest TYS to CHS flight.
How many flights per day from McGhee Tyson Airport (TYS) to Charleston Intl. Airport (CHS)?
There are no daily direct flights from McGhee Tyson Airport (TYS) to Charleston Intl. Airport (CHS). But you can book flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be on your way in no time at all.
What day of the week has the most flights from TYS to CHS?
Friday is typically the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can vary based on a number of factors, such as the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from McGhee Tyson Airport (TYS) to Charleston Intl. Airport (CHS)?
To reach Charleston Intl. Airport (CHS) without delays, select a flight that leaves from McGhee Tyson Airport (TYS) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from McGhee Tyson Airport (TYS) to Charleston Intl. Airport (CHS) last-minute?
Last-minute fares from TYS to CHS are generally more expensive. To secure the cheapest rates, start looking for flights well ahead of time. That said, if you can play around with your travel dates, it's possible to score a cheap fare right before your trip.
Is it cheaper to book a TYS to CHS flight and hotel package?
Opting for a TYS to CHS flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip in one place. Choose from our impressive range of stays and then add activities, flights and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from McGhee Tyson Airport (TYS) to Charleston Intl. Airport (CHS)?
In most cases, you can reschedule or cancel your TYS to CHS flight. However, there may be additional fees, especially if you booked more than 24 hours ago. Check your itinerary for the airline's rules and fees on flight changes, or if you'd like more details, head to our Customer Service portal.

Travel information

Origin airport
McGhee Tyson
Destination airport
Charleston Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$202
Distance
302 mi

Book with confidence

Knoxville to Charleston Flights

The cheapest times to fly from Knoxville to Charleston

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Knoxville to Charleston are during the month of December. You can find some of the cheapest flights from Knoxville to Charleston with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Knoxville to Charleston

Sunday is one of the best days to book for cheap flights from Knoxville to Charleston: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Knoxville to Charleston

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Knoxville to Charleston in 2025. You can also book with separate airlines for your outbound and return journeys, from $102 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Knoxville to Charleston flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Knoxville to Charleston airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Knoxville to Charleston Flights

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*Available to One Key members.