$557 Cheap Flights from Knoxville (TYS) to Santa Cruz de Tenerife (TFN)

View $557 flight on Mon, Dec 1, 2025Opens in a new window

Popular airlines from McGhee Tyson Airport (TYS) to Santa Cruz de Tenerife (TFN-Tenerife North)

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Cheap Flights from Knoxville to Santa Cruz de Tenerife (TYS-TFN)

Prices were available within the past 7 days and start at $557 for one-way flights and $720 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

British Airways
Thu, Jan 15 - Tue, Jan 20
TYS
Knoxville
TFN
Tenerife
$720 Roundtrip, found 2 days ago
$720
Roundtrip
found 2 days ago
Select British Airways flight, departing Thu, Jan 15 from Knoxville to Tenerife, returning Tue, Jan 20, priced at $720 found 2 days ago
British Airways
Thu, Jan 15 - Tue, Jan 20
TYS
Knoxville
TFN
Tenerife
$940 Roundtrip, found 2 days ago
$940
Roundtrip
found 2 days ago
Select British Airways flight, departing Thu, Jan 15 from Knoxville to Tenerife, returning Tue, Jan 20, priced at $940 found 2 days ago
British Airways
Thu, Jan 15 - Tue, Jan 20
TYS
Knoxville
TFN
Tenerife
$1,082 Roundtrip, found 2 days ago
$1,082
Roundtrip
found 2 days ago
Select British Airways flight, departing Thu, Jan 15 from Knoxville to Tenerife, returning Tue, Jan 20, priced at $1,082 found 2 days ago
American Airlines
Fri, Dec 12 - Thu, Dec 25
TYS
Knoxville
TFN
Tenerife
$1,120 Roundtrip, found 2 days ago
$1,120
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Dec 12 from Knoxville to Tenerife, returning Thu, Dec 25, priced at $1,120 found 2 days ago
British Airways
Thu, Jan 15 - Tue, Jan 20
TYS
Knoxville
TFN
Tenerife
$1,137 Roundtrip, found 2 days ago
$1,137
Roundtrip
found 2 days ago
Select British Airways flight, departing Thu, Jan 15 from Knoxville to Tenerife, returning Tue, Jan 20, priced at $1,137 found 2 days ago
British Airways
Thu, Jan 15 - Tue, Jan 20
TYS
Knoxville
TFN
Tenerife
$1,188 Roundtrip, found 2 days ago
$1,188
Roundtrip
found 2 days ago
Select British Airways flight, departing Thu, Jan 15 from Knoxville to Tenerife, returning Tue, Jan 20, priced at $1,188 found 2 days ago
British Airways
Thu, Jan 15 - Tue, Jan 20
TYS
Knoxville
TFN
Tenerife
$1,193 Roundtrip, found 3 days ago
$1,193
Roundtrip
found 3 days ago
Select British Airways flight, departing Thu, Jan 15 from Knoxville to Tenerife, returning Tue, Jan 20, priced at $1,193 found 3 days ago
British Airways
Thu, Jan 15 - Tue, Jan 20
TYS
Knoxville
TFN
Tenerife
$1,203 Roundtrip, found 2 days ago
$1,203
Roundtrip
found 2 days ago
Select British Airways flight, departing Thu, Jan 15 from Knoxville to Tenerife, returning Tue, Jan 20, priced at $1,203 found 2 days ago
British Airways
Sun, Jun 7 - Mon, Jun 15
TYS
Knoxville
TFN
Tenerife
$1,213 Roundtrip, found 5 days ago
$1,213
Roundtrip
found 5 days ago
Select British Airways flight, departing Sun, Jun 7 from Knoxville to Tenerife, returning Mon, Jun 15, priced at $1,213 found 5 days ago
United
Wed, Dec 17 - Fri, Dec 26
TYS
Knoxville
TFN
Tenerife
$1,699 Roundtrip, found 10 hours ago
$1,699
Roundtrip
found 10 hours ago
Select United flight, departing Wed, Dec 17 from Knoxville to Tenerife, returning Fri, Dec 26, priced at $1,699 found 10 hours ago

Frequently asked questions

How much does a flight from McGhee Tyson Airport (TYS) to Tenerife North Airport (TFN) cost?
Grab a cheap one-way flight from $557 or cheap return flight from $720 from McGhee Tyson Airport (TYS) to Tenerife North Airport (TFN) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from McGhee Tyson Airport (TYS) to Tenerife North Airport (TFN)?
The cheapest month to fly from TYS to TFN is January, when demand is low. Off-peak months are typically when you'll find cheap fares for travel between these airports.
What is the cheapest airline that flies from McGhee Tyson Airport (TYS) to Tenerife North Airport (TFN)?
Use the filters on Expedia to compare airlines and find the most affordable carrier that'll take you from TYS to TFN. Then, sort your results by "Price (lowest to highest)" to snap up a good deal.
How many flights per day from McGhee Tyson Airport (TYS) to Tenerife North Airport (TFN)?
Nonstop flights from McGhee Tyson Airport (TYS) to Tenerife North Airport (TFN) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your travel details and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from TYS to TFN?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can vary depending on various factors, including the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from McGhee Tyson Airport (TYS) to Tenerife North Airport (TFN)?
Select a flight from McGhee Tyson Airport (TYS) to Tenerife North Airport (TFN) that takes off before 3 PM to reduce the risk of delays and cancellations. Departures later than this have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from McGhee Tyson Airport (TYS) to Tenerife North Airport (TFN) last-minute?
Last-minute bookings from TYS to TFN are typically more expensive. To lock in the best rates, start looking for flights well ahead of time. That said, if you're flexible with your travel dates, it's possible to land a cheap fare right before your journey.
Is it cheaper to book a TYS to TFN flight and hotel package?
Compared with arranging hotels and flights separately, booking a TYS to TFN flight and hotel package with Expedia could result in significant savings. Better still, managing everything in one place will take the stress out of planning your trip. Simply pick your flights and choose from our extensive range of hotels, then customize your trip with other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from McGhee Tyson Airport (TYS) to Tenerife North Airport (TFN)?
It's generally possible to cancel or reschedule your TYS to TFN flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
McGhee Tyson
Destination airport
Tenerife North
Airlines serving
American Airlines, Delta, KLM
Roundtrip price
$719
Distance
3911 mi

Book with confidence

Knoxville to Santa Cruz de Tenerife Flights

The cheapest times to fly from Knoxville to Santa Cruz de Tenerife

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Knoxville to Santa Cruz de Tenerife are during the month of January. You can find some of the cheapest flights from Knoxville to Santa Cruz de Tenerife with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Knoxville to Santa Cruz de Tenerife

Sunday is one of the best days to book for cheap flights from Knoxville to Santa Cruz de Tenerife: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Knoxville to Santa Cruz de Tenerife

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Knoxville to Santa Cruz de Tenerife in 2025. You can also book with separate airlines for your outbound and return journeys, from $557 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Knoxville to Santa Cruz de Tenerife flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Knoxville to Santa Cruz de Tenerife airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Knoxville to Santa Cruz de Tenerife Flights

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*Available to One Key members.