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Compare San Sisto 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Giotto Hotel & Spa

4.0 star property
8.8 out of 10, Excellent, (713)
"Great experience..amazing location "
$89 nightly
The price is $105
Jul 29 - Jul 30
Total includes taxes and fees
Giotto Hotel & Spa

Hotel Fontebella

4.0 star property
8.6 out of 10, Excellent, (606)
"Central location, lovely views, helpful staff."
$97 nightly
The price is $114
Jul 24 - Jul 25
Total includes taxes and fees
Hotel Fontebella

TH Assisi - Hotel Cenacolo

4.0 star property
9.0 out of 10, Wonderful, (566)
"4 star hotel but feels like 5 stars!"
$84 nightly
The price is $99
Aug 7 - Aug 8
Total includes taxes and fees
TH Assisi - Hotel Cenacolo

Hotel Sangallo Palace

4.0 star property
8.8 out of 10, Excellent, (578)
"Everything was excellent!!!"
$129 nightly
The price is $147
Jul 31 - Aug 1
Total includes taxes and fees
Hotel Sangallo Palace

Best Western Hotel Quattrotorri Perugia

4.0 star property
8.6 out of 10, Excellent, (341)
"Great stay "
$92 nightly
The price is $106
Aug 6 - Aug 7
Total includes taxes and fees
Best Western Hotel Quattrotorri Perugia

La Meridiana Bleisure Hotel

4.0 star property
8.4 out of 10, Very Good, (325)
"Restraunt food was ok "
$105 nightly
The price is $120
Jul 30 - Jul 31
Total includes taxes and fees
La Meridiana Bleisure Hotel

Posta Donini 1579 UNA Esperienze

4.0 star property
9.2 out of 10, Wonderful, (242)
"A lovely place to spend a few nights "
$145 nightly
The price is $164
Jul 27 - Jul 28
Total includes taxes and fees
Posta Donini 1579 UNA Esperienze

Hotel Priori Secret Garden

4.0 star property
9.6 out of 10, Exceptional, (152)
"In the heart of the action, yet removed enough to sleep like a baby, we had a fabulous stay at Priori Secret Garden. Looking forward to going back next year."
Hotel Priori Secret Garden

BV Grand Hotel Assisi

4.0 star property
8.6 out of 10, Excellent, (293)
"Staff was wonderful, food delicious "
$89 nightly
The price is $105
Jul 24 - Jul 25
Total includes taxes and fees
BV Grand Hotel Assisi

Perusia Hotel

4.0 star property
8.0 out of 10, Very Good, (571)
"The staff were lovely (especially Angelo) and receptionists spoke English. Hotel very clean and light. Rooms decent size. Wi-Fi and TV reception useless! The restaurant was not open and apart from a couple of bars nowhere to eat nearby without walking into the City. About a 20 minute walk into Perugia. "
Perusia Hotel

Hotel Giò Wine e Jazz Area

4.0 star property
8.6 out of 10, Excellent, (555)
"Although a bit dated, the concept of a wine and jazz hotel is fantastic. The atmosphere was great, especially when there was live music. E.g. for breakfast! A bit pricey for what you get, but I would definitely go again."
$246 nightly
The price is $275
Aug 4 - Aug 5
Total includes taxes and fees
Hotel Giò Wine e Jazz Area

Perugia Park Hotel

4.0 star property
8.4 out of 10, Very Good, (373)
"Great location in Perugia. A mere 15 min drive from the town center. Beautiful and clean."
$103 nightly
The price is $119
Jul 25 - Jul 26
Total includes taxes and fees
Perugia Park Hotel

Hotel Villa Paradiso

4.0 star property
7.6 out of 10, Good, (84)
"Overally good"
$105 nightly
The price is $120
Jul 27 - Jul 28
Total includes taxes and fees
Hotel Villa Paradiso

Hotel Perugia Plaza

4.0 star property
8.2 out of 10, Very Good, (199)
"Staff excellent. Would have been nice to get a coffee, tea or a drink in the lobby area."
Hotel Perugia Plaza

Hotel Lidò

4.0 star property
8.0 out of 10, Very Good, (135)
"Lovely countryside hotel"
Hotel Lidò

Relais dell'Olmo

4.0 star property
9.2 out of 10, Wonderful, (208)
"A great place to stay, quiet and charming, a short distance from Perugia."
$146 nightly
The price is $166
Jul 28 - Jul 29
Total includes taxes and fees
Relais dell'Olmo

Hotel Valle di Assisi Spa & Golf

4.0 star property
9.2 out of 10, Wonderful, (194)
"Staff were professional and extremely helpful. Breakfast was the best in Italy so far. Dinners were amazing."
$143 nightly
The price is $164
Jul 28 - Jul 29
Total includes taxes and fees
Hotel Valle di Assisi Spa & Golf

Abbazia Collemedio Resort & Spa

4.0 star property
9.2 out of 10, Wonderful, (56)
"This was a charming property with a stunning views of the Umbrian countryside and also served a beautiful breakfast. The service was excellent! Would definitely stay here again! Recommending this hotel to others!"
$135 nightly
The price is $149
Jul 28 - Jul 29
Total includes taxes and fees
Abbazia Collemedio Resort & Spa

Hotel Ristorante La Bastiglia

4.0 star property
8.0 out of 10, Very Good, (69)
"Nice place to stay "
$70 nightly
The price is $85
Jul 28 - Jul 29
Total includes taxes and fees
Hotel Ristorante La Bastiglia

Locanda della Posta Boutique Hotel

4.0 star property
9.6 out of 10, Exceptional, (174)
"Very nice w large rooms helpful staff fantastic location"
Locanda della Posta Boutique Hotel
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in San Sisto.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about San Sisto

Check out the local area in San Sisto as you venture to sights like Perugina Chocolate Factory.

Top San Sisto Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in San Sisto?
If you're looking for deluxe comfort and plenty of amenities on your San Sisto getaway, consider Hotel La Meridiana. This sought-after 4-star hotel offers a terrace and a rooftop terrace. Arte Hotel Perugia also gets stellar reviews from Expedia customers. Concierge services and a rainfall shower-head are among its conveniences.
How much does it cost to stay in a 4-star hotel in San Sisto?
To book a 4-star hotel in San Sisto that's within your budget, use Expedia's handy filter tool. Take a look at the availability during your vacation dates and use our pricing filter to set your limit. You can also sort your results by the most budget-friendly escape first.

  • Search for the lowest price from $269

What's the difference between 5-star and 4-star hotels in San Sisto?
Give yourself the luxury treatment during your San Sisto escape by choosing a 4-star hotel. As well as featuring upmarket surroundings, these retreats are typically filled with amenities, including bathrobes, large beds and more. A 5-star hotel will go the extra mile to make your stay an even more lavish and unforgettable one. 24-hour concierge assistance, on-site spas and world-class dining are just the start of the exclusive services and conveniences you'll likely be able to enjoy.