Find 4 Star Hotels in Santa Fe from $63

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Compare Santa Fe 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Santa Fe 4-star hotels

InterTower Hotel

4.0 star property
8.8 out of 10, Excellent, (199)
"Excelent place to stay."
$82 nightly
The price is $82
Sep 7 - Sep 8
InterTower Hotel

Los Silos Hotel

4.0 star property
9.4 out of 10, Exceptional, (24)
"Unique, interesting, and very nice. Staff was outstanding. We will be back soon"
$106 nightly
The price is $106
Sep 12 - Sep 13
Los Silos Hotel

Agustín 1 Apart

4.0 star property
9.0 out of 10, Wonderful, (4)
$63 nightly
The price is $63
Sep 7 - Sep 8
Agustín 1 Apart
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Learn more about Santa Fe

Discover colonial architecture and vibrant history at Plaza 25 de Mayo, where the Metropolitan Cathedral stands as a stunning centerpiece. Kayak along the Paraná River or visit the riverside Parque del Sur for sunset views across the water.

Santa Fe showing night scenes, a festival and a city
Photo by Silvio Moriconi/Argentina Travel
Open Photo by Silvio Moriconi/Argentina Travel

Top Santa Fe Hotel Reviews

Find out more about Santa Fe

Find out more about Santa Fe

The outset of any well-deserved trip kicks off with deciding on a wonderful location. Santa Fe is a popular option with tourists because of all its local amenities. Location is everything, but that accounts for more than the city you are flying into. When you want to make your future holiday unforgettable, it's all about where you start each new day.

Accommodations as Stunning as the City

Santa Fe saw its fair share of visitors last year. Our review section provides tips and tricks on which hotel will meet your needs for an incredible vacation. When you book a 4-star hotel you can rest easy knowing that these properties are designed to fulfill your expectations. You'll never need to venture far for a delectable meal, to keep up with your workout schedule, or an energizing plunge during your visit, thanks to all that these hotels provide. They strive to make the grounds and facilities hospitable from the instant you step onto the property and with each step throughout the hotel.

Rooms have been designed to keep your utmost comfort in mind, with amenities like in-room tea or coffee, specially designed bathroom products, and ultra-comfortable bedding. So, lay back and decompress. Moreover, if you find that you are need of anything further, you can rest easy the staff will try their best to ensure you continue to be happy during your time there. These properties are so nice that you'll regret the day you have to check-out.

Book a 4-Star Hotel in Santa Fe Today!

Your trip to Santa Fe should be a complete retreat from your daily worries. Of course, your vacation should be focused on getting the most out of your destination. And getting the most often means giving yourself the best. Expedia has 4-star hotels that allow you to do just that. Reserve with Expedia today!

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What are the best 4-star hotels in Santa Fe?
Create amazing memories in Santa Fe at InterTower Hotel. Highly rated by Expedia guests, this 4-star hotel offers lots of conveniences for a relaxing and comfortable stay.
How much does it cost to stay in a 4-star hotel in Santa Fe?
To book a 4-star hotel in Santa Fe that matches your budget, take advantage of Expedia's filter tool. Check out what's available during your chosen dates and use our pricing filter to set your limit. You can also sort your results by the most economical retreat first.

  • Search for the lowest price from $63

What's the difference between 5-star and 4-star hotels in Santa Fe?
If you decide to vacation at a 4-star hotel in Santa Fe, you'll usually find loads of amenities to make sure you're comfortable, such as a gym, restaurant and pool. You can enjoy high-quality service and upscale accommodations. Opt for a 5-star hotel and you'll have access to a few more bells and whistles — think concierge assistance, on-site spas and nightly turndown services. You're likely to get extra amenities and first-rate services at a 5-star getaway, though both are fabulous options for luxury guests.