A cityscape with a prominent historical building in the center, surrounded by modern high-rise buildings and a river in the background.

Find 5 Star Hotels in Santa Fe from $105

  • Upfront pricing

    Our total price for your stay includes taxes and fees

  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check availability on Santa Fe 5 Star Hotels

This weekend
Jul 3 - Jul 5
Next weekend
Jul 10 - Jul 12
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Fe.
InterTower Hotel

InterTower Hotel

San Jeronimo 2779 Santa Fe Santa Fe
$105 nightly
The price is $105 total per night from Jul 12 to Jul 13
$105 total
Jul 12 - Jul 13
Still don't see what you're looking for?
See all properties in Santa Fe.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santa Fe

Discover colonial architecture and vibrant history at Plaza 25 de Mayo, where the Metropolitan Cathedral stands as a stunning centerpiece. Kayak along the Paraná River or visit the riverside Parque del Sur for sunset views across the water.

See all hotels in Santa Fe
A red suspension bridge over a river with surrounding greenery.

Top Santa Fe Hotel Reviews

Find out more about Santa Fe

Treat your every whim on your impending break. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Santa Fe so popular in the last year. There's no reason to delay a getaway to Santa Fe any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Reserve one of our 5-star hotels in Santa Fe and indulge in the finer things in life for a while. Don't wait any longer!

Book the Best Santa Fe 5-Star Hotels

You'll have a wonderful time at one of these 5-star hotels. Highly-rated eateries, concierges, and pillow-fluffing are all at the ready. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. How do you want to relax? 24-hour room service, so you can order that chocolate soufflé© in the wee hours of the morning? A mud wrap treatment that will leave you feeling outstanding? Butler services? Whatever it is your heart desires, you're bound to find it here. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs.

Can't wait to get outside? We hear you. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Santa Fe are waiting for you to rest up after an exciting day.

Your Getaway Starts Today

The results are in, and Santa Fe 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. It's time to indulge yourself -- Expedia can help you land a great deal on accommodation. Decide on one of the 5-star hotels in Santa Fe today and decompress in total tranquility tomorrow.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Santa Fe?
How much you pay for a 5-star hotel in Santa Fe depends on things such as when you plan to travel and the length of your vacation. An insider tip for scoring the best deal? Use our pricing filters to check out all of the available hotels for your preferred dates.

  • Search for the lowest price per night from $105

What makes a hotel 5 stars in Santa Fe?
From gourmet restaurants and 24-hour gyms to pools and dreamy bedding, the 5-star experience in Santa Fe is all about comfort and luxury. But it takes more than just top-notch amenities to receive a 5-star rating. Hotels also have to offer extraordinary guest-centric services like in-room massages, on-site dry cleaning and laundry and 24-hour room service.
Are there any 5-star all-inclusive resorts in Santa Fe?
Our filters are the quickest way to find exactly what you want. Check the "All inclusive" and "5-star" boxes to see the most upscale properties in Santa Fe where your accommodations, meals, activities and entertainment are included in the upfront price. At these escapes, your trip is pure leisure from the moment you check in.

Explore a world of travel with Expedia