A red brick building with a white dome and a flagpole with flags.

Find 5 Star Hotels in Oxford, NC from $168

  • Upfront pricing

    Our total price for your stay includes taxes and fees

  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check availability on Oxford 5 Star Hotels

This weekend
Nov 6 - Nov 8
Next weekend
Nov 13 - Nov 15
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Oxford.
21c Museum Hotel Durham

21c Museum Hotel Durham

111 North Corcoran Street Durham NC
$148 nightly
The price is $168 total per night from Nov 27 to Nov 28
$168 total
Nov 27 - Nov 28
Total with taxes and fees
Still don't see what you're looking for?
See all properties in Oxford.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Oxford

Stroll past historic tobacco warehouses and elegant Victorian homes in this charming small town with a vibrant Main Street. Visit during the annual Hot Sauce Contest or explore Granville County Museum to discover the region's rich agricultural heritage.

See all hotels in Oxford
A red brick building with a white dome and a flagpole with flags.

Top Oxford Hotel Reviews

Find out more about Oxford

There's nothing wrong with enjoying the finer things in life. Add further luxury on your next trip to Oxford by treating yourself to the best of the best when it comes to lodging. It's an ideal pairing. There's no reason to delay a getaway to Oxford any longer. You'll join the multitudes of vacationers who have made Oxford so fashionable recently. We should also mention, the hotels in this area receive noteworthy marks for customer service, so you know you'll be looked after during your getaway. What are you waiting for? Book one of Expedia's luxurious 5-star hotels in Oxford and get ready to enjoy the getaway of a lifetime.

5-Star Hotels in Oxford

Don't be afraid to request the best service from your hotel, along with pristine rooms. High-end restaurants, concierges, and in-room massages are all at the ready. You're sure to find exactly the accommodation you need. Not only that, the hotels in this area receive noteworthy marks for guest services, so you know you'll want for nothing during your getaway. What kind of amenities will make your stay a wonderful one? 24-hour room service, so you can order that chocolate soufflé© in the wee hours of the morning? A reflexology treatment that will leave you feeling outstanding? Butler services? Whatever it is your heart desires, you're bound to find it here.

Can't wait to get outside? We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in Oxford are waiting for you to rest up after a busy day. Ready to learn more? Plenty of visitors recommend this location.

Make Your Escape

The results are in, and Oxford 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. It's time to indulge yourself -- Expedia can help you land a great deal on accommodation. Choose one of Expedia's Oxford 5-star hotels today and soothe yourself in complete comfort at your convenience.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Oxford?
The amount you pay for a 5-star hotel in Oxford can vary depending on the time of year you travel and how long you plan to be away, among a number of factors. Take advantage of our price per night filter and other search tools to find the best rate on a high-end stay.

  • Search for the lowest price per night from $168

What makes a hotel 5 stars in Oxford?
From fine dining restaurants and 24-hour gyms to swimming pools and the finest bedding, the 5-star experience in Oxford is all about comfort and indulgence. But it requires more than just upscale conveniences to receive a 5-star rating. Accommodations also have to deliver extraordinary guest-focused services like in-room massages, laundry and dry cleaning and room service any time night or day.
Are there any 5-star all-inclusive resorts in Oxford?
Find an upscale escape that includes your lodging, meals, drinks and entertainment in Oxford with the help of Expedia's filters. Search for resorts rated 5 stars and select the "All inclusive" filter. Be sure to check what's included in the purchase price. That way, you'll be ready to maximize all the premium perks when you get there.

Explore a world of travel with Expedia