Durham Vacation Rentals

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Our top choices for Durham vacation rentals

10.0 out of 10, Exceptional, (12)
"Able to walk to stores and places to eat"
United States
Catherine P.
$190 nightly
The price is $215
Dec 27 - Dec 28
Total with taxes and fees
New & Clean 2 Bed Walltown Home. Walk to Duke! B
9.2 out of 10, Wonderful, (9)
"I really appreciate that the space was simple and clean. The location has easy access to freeways. We loved the Museum of Life Science, it was 11 minutes away and a great way to spend time with kids."
United States
Jimmeka T.
$150 nightly
The price is $170
Dec 28 - Dec 29
Total with taxes and fees
Recently Renovated Chic Durham Farmhouse
9.6 out of 10, Exceptional, (25)
"Great communication. Very comfortable bed and charming space. Will stay again."
United States
Francesca G.
$166 nightly
The price is $169
Jan 12 - Jan 13, 2026
Total with taxes and fees
Historic|Twinkling Patio|Great Downtown Location!
2.0 star property
10.0 out of 10, Exceptional, (1)
"I felt very comfortable at this cottage. My wife and I enjoyed the kitchen and walk in closet. Laundry on site! There were dishes and pots and pans. A microwave and full size oven and refrigerator. It was very clean and it suited our needs perfectly!"
United States
Kevin
$144 nightly
The price is $163
Dec 29 - Dec 30
Total with taxes and fees
Lakewood Lyon Park Renovated Cottage Near Duke 26B
9.6 out of 10, Exceptional, (5)
"Very cool property!"
United States
Jessica L.
$195 nightly
The price is $221
Jan 20 - Jan 21, 2026
Total with taxes and fees
100 Year-Old Historic Brick 2BR Loft High Ceiling5

Apartment in Trinity Park

Sunny efficiency in historic home
10.0 out of 10, Exceptional, (19)
"Very convenient and close to everything!"
United States
Brian M.
$212 nightly
The price is $240
Jan 13 - Jan 14, 2026
Total with taxes and fees
Sunny efficiency in historic home
9.6 out of 10, Exceptional, (12)
"Clean, spacious, great location"
United States
Mindy A.
$193 nightly
The price is $219
Dec 29 - Dec 30
Total with taxes and fees
Walk to Duke Campus! 3 Bedroom in Trinity Park!
10.0 out of 10, Exceptional, (31)
"Loved the surrounding area and the place itself. Made great memories!"
United States
Melissa R.
$254 nightly
The price is $288
Jan 12 - Jan 13, 2026
Total with taxes and fees
Cozy Bungalow near Duke & Dining, Walkable Area
9.6 out of 10, Exceptional, (4)
"This was the perfect place for our long weekend visit to Durham! Everything is well maintained and comfortable. Great communication with the owners. It had everything we needed and we will definitely stay again when we are in town again."
United States
Ronda M.
$150 nightly
The price is $170
Dec 30 - Dec 31
Total with taxes and fees
Renovated, Clean 1 bedroom in Forest Hills - A
10.0 out of 10, Exceptional, (1)
"The property is everything MOST people could ask for. The charm of the rental and property were amazing. Very close to lots of amazing places to eat and shop. Highly recommend."
United States
Rebecca G.
$240 nightly
The price is $272
Jan 19 - Jan 20, 2026
Total with taxes and fees
Convenient to Duke Hosp/Univ & Walkable to DT
8.8 out of 10, Excellent, (10)
"Stayed while son was attending a nearby camp for the week. Property management was great. Was nice to have a pet friendly place and so many pet friendly restaurants and parks near by! "
United States
carrie h.
$209 nightly
The price is $237
Jan 20 - Jan 21, 2026
Total with taxes and fees
100 Year-Old Historic Brick 2BR Loft -Large Patio1

Vacation Home in Durham

Duke Hospital Zero-Step 1BR
9.4 out of 10, Exceptional, (8)
"It was perfect for our needs. "
United States
But Where's T.
$211 nightly
The price is $240
Jan 11 - Jan 12, 2026
Total with taxes and fees
Duke Hospital Zero-Step 1BR
8.4 out of 10, Very Good, (8)
"5 stars *****Very nice property, very clean! Great neighborhood and close to everything! Great communication with owners! They also went out of their way to mail a wallet left behind, and we are so thankful!"
United States
LaTisha P.
$230 nightly
The price is $261
Jan 5 - Jan 6, 2026
Total with taxes and fees
Balcony - Downtown - Duke - UNC - Pet Friendly
2.0 star property
$193 nightly
The price is $219
Jan 3 - Jan 4, 2026
Total with taxes and fees
Renovated 2 Bed Walltown Home Walk to Duke B
8.4 out of 10, Very Good, (5)
"Was a terrific apartment to rent—all the amenities you could ask for and a safe, quiet location. I’d book with this company again."
United States
Heidi H.
$280 nightly
The price is $296
Jan 12 - Jan 13, 2026
Total with taxes and fees
★Cozy Crib★ King Bed★ Long Term Stays ★ Duke ★
9.0 out of 10, Wonderful, (12)
"We recently stayed here with my dog and kids! Stay was amazing!! House was clean"
United States
Mechael W.
$242 nightly
The price is $275
Jan 4 - Jan 5, 2026
Total with taxes and fees
Orchid 2BR Suite @ Forest Hills
8.8 out of 10, Excellent, (3)
"I was staying a couple nights in town for work and this place was almost perfect for it. Location is great and on a quiet street."
United States
Bradley V.
$156 nightly
The price is $177
Jan 22 - Jan 23, 2026
Total with taxes and fees
Charming 1-bedroom apartment in near Duke University and Downtown Durham
9.6 out of 10, Exceptional, (5)
"This stay was great for my overnight stay in Durham for work. "
United States
Bradley V.
$143 nightly
The price is $162
Dec 28 - Dec 29
Total with taxes and fees
Lakewood/Lyon Park Renovated Cottage Near Duke 28B
8.0 out of 10, Very Good, (2)
"we spent two nights in three days in Durham. We were bringing our granddaughter’s to see the place. We had lived many years. We had a great visit!"
United States
Sara J.
$197 nightly
The price is $224
Jan 20 - Jan 21, 2026
Total with taxes and fees
100 Year-Old Historic Brick 2BR Loft High Ceiling7
9.6 out of 10, Exceptional, (59)
"Great house in lovely residential neighborhood. Close to Duke’s campus. Stayed with our dog who loved the many parks within walking distance and the State Parks a short drive away. "
United States
Anna M.
$367 nightly
The price is $415
Jan 20 - Jan 21, 2026
Total with taxes and fees
Cozy Bull City Home*1.5 mi to Duke* Dog friendly
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Durham Hotel Reviews

Find out more about Durham

Everything you need to know about Durham vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Durham vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Durham vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Durham vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Durham. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Durham in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $128 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Durham rentals

At Expedia, we put the best Durham vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Durham rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Durham vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Durham. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in Durham?

Yes, we give you a choice of vacation rentals in Durham close to Sarah P. Duke Gardens, or you can choose a more remote option if you'd like a relaxing place to stay. Tourists who visit Durham speak highly of the college campus and array of shops. While you're in the area, you can also enjoy the top-notch restaurants and live music.

What's the top vacation rental that Durham has to offer?

Bungalow near Duke and Downtown Durham: Visitors like this Durham vacation home rental. It has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a stovetop, and a microwave, so you can cook with friends or family. Some other top choices in Durham are Charming private home in Durham and Luxurious 5-bedroom house with swim-spa, fitness&weight room, game room, & more!.

How many vacation rentals are there in Durham?

Expedia has 388 vacation rentals for your stay in Durham.

What’s there to see and do in Durham?

Cultural attractions include Carolina Theatre and Durham Performing Arts Center, whereas Sarah P. Duke Gardens and Eno River State Park are a couple of picturesque spots to enjoy the outdoors. Other places in town to visit include American Tobacco Campus and Durham Bulls Athletic Park.

What’s a vacation rental in Durham like?

A vacation rental is a private property where you can stay for several days or longer in Durham. Vacation rentals offer amenities like laundry facilities and kitchens so you'll feel right at home. If you're concerned about cleanliness, vacation rentals can provide a sense of security away from shared hotel elevators and busy front desks while still allowing you the enjoyment of travel. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental an attractive choice for a family getaway.