Title: The Best 5 Star Hotels in Poplar Bluff, MO  | Expedia.com

[Poplar Bluff Travel Guide](https://expedia.com/Poplar-Bluff.dx9449)[Hotels in Poplar Bluff](https://expedia.com/Poplar-Bluff-Hotels.d9449.Travel-Guide-Hotels)[Vacation Rentals in Poplar Bluff](https://expedia.com/Poplar-Bluff-Vacation-Rentals.d9449.Travel-Guide-VacationRentals)[Flights to Poplar Bluff](https://expedia.com/Cheap-Flights-To-Poplar-Bluff.d9449.Travel-Guide-Flights)[Car Rentals in Poplar Bluff](https://expedia.com/Car-Rentals-In-Poplar-Bluff.d9449.Car-Rental-Guide)[Poplar Bluff Vacation Packages](https://expedia.com/Poplar-Bluff.d9449.Destination-Travel-Guides)

![Mini Takes the States 2014 Road Rally Memphis to St.Louis Leg:

Moark Regional Railroad Museum
HOURS: Saturdays 1 p.m. - 4 p.m.

It was not open when I stopped by but there are a few rail cars outside. Poplar has a train rich history.

This was a cool little town to stop in and take pictures. Lot's of wall murals for some reason, and some very cool architecture. Worth the stop and be sure and enjoy a lunch at Hayden's Drive-In ! 

#MTTS2014 #minitakesthestates #go11
#train](https://images.trvl-media.com/place/9449/f87e8b74-cb32-40ea-afa8-0f245bfdc84b.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Bill Dillard

![](https://images.trvl-media.com/place/9449/f87e8b74-cb32-40ea-afa8-0f245bfdc84b.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg)  
###  
Upfront pricing  
Our total price for your stay includes taxes and fees
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg)  
###  
Treat yourself  
Save 10% or more on over 100,000 hotels worldwide with Member Prices  
[Learn about One Key](https://www.expedia.com/welcome-one-key)
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg)  
###  
Be picky  
Search almost a million properties worldwide

## Check availability on Poplar Bluff 5 Star Hotels

Tonight

[Mar 18 - Mar 19](https://www.expedia.com/Hotel-Search?regionId=9449&startDate=2026-03-18&endDate=2026-03-19&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 19 - Mar 20](https://www.expedia.com/Hotel-Search?regionId=9449&startDate=2026-03-19&endDate=2026-03-20&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=9449&startDate=2026-03-20&endDate=2026-03-22&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=9449&startDate=2026-03-27&endDate=2026-03-29&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg)

Save an average of 15% on thousands of hotels when you're signed in

[Sign in

](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Poplar-Bluff-Hotels.s50-0-d9449.Travel-Guide-Filter-Hotels)[

Sign up, it's free

](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Poplar-Bluff-Hotels.s50-0-d9449.Travel-Guide-Filter-Hotels)

## Learn more about Poplar Bluff

Outdoor enthusiasts flock to Lake Wappapello for boating and fishing, while the historic downtown reveals Poplar Bluff's riverboat-era charm. Visit the Black River Heritage Center first to understand the region's history before exploring the scenic Ozark foothills on nearby hiking trails.

[See all hotels in Poplar Bluff](https://www.expedia.com/Hotel-Search?startDate=2026-04-01&endDate=2026-04-02&adults=2&regionId=9449)

![Mini Takes the States 2014 Road Rally Memphis to St.Louis Leg:

Moark Regional Railroad Museum
HOURS: Saturdays 1 p.m. - 4 p.m.

It was not open when I stopped by but there are a few rail cars outside. Poplar has a train rich history.

This was a cool little town to stop in and take pictures. Lot's of wall murals for some reason, and some very cool architecture. Worth the stop and be sure and enjoy a lunch at Hayden's Drive-In ! 

#MTTS2014 #minitakesthestates #go11
#train](https://images.trvl-media.com/place/9449/f87e8b74-cb32-40ea-afa8-0f245bfdc84b.jpg?impolicy=fcrop&w=899&h=600&p=1&q=high)

Photo by Bill Dillard

## Top Poplar Bluff Hotel Reviews

## Find out more about Poplar Bluff

There's nothing wrong with enjoying the finer things in life. Why not demand the best of accommodations during your excursion to Poplar Bluff? There's no reason to delay a getaway to Poplar Bluff any longer. You'll join the multitudes of vacationers who have made Poplar Bluff so fashionable in the last year. Additionally, the hotels in this area are known for guest services, so you know you'll want for nothing during your getaway. You deserve the great vacation you're dreaming about. Our 5-star hotels in Poplar Bluff are the perfect places to relax in when you really need to escape.

### 5-Star Hotels in Poplar Bluff

Don't be afraid to live the high life while you're on vacation, along with the best conditions. Exceptional customer care, luxurious bedding, and fabulous spa offerings are all on offer. You're sure to find exactly the accommodation you need. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What creature comforts do you want in your lodging? 24-hour room service, so you can order that chocolate soufflé© in the wee hours of the morning? A mud wrap treatment that will leave you feeling like a million bucks? Butler services? Whatever it is your heart desires, you're bound to find it here. 

You won't sleep and order room service the entire time, though. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in Poplar Bluff are the perfect place to relax after an exciting day. Ready to learn more? Plenty of visitors recommend this location. 

### Make Your Escape

The results are in, and Poplar Bluff 5-star hotels are the place to be when you book your next vacation. Additionally, these accommodations are highly rated -- 90% of visitors recommended 5-star hotels in Poplar Bluff! It's time to plan your next great escape -- Expedia can help you land a great deal on accommodation. Select one of the 5-star hotels in Poplar Bluff today and relax in luxe surroundings when you're ready.

## Frequently asked questions

### How much does it cost to stay in a 5-star hotel in Poplar Bluff?

> - Search for the lowest price per night

### What makes a hotel 5 stars in Poplar Bluff?

### Are there any 5-star all-inclusive resorts in Poplar Bluff?

## Explore a world of travel with Expedia

- Lodging
- Flights
- Packages
- Cars
- Vacation Rentals

- [Hotels near Margaret Harwell Art Museum ](https://www.expedia.com/Margaret-Harwell-Art-Museum-Hotels.0-l553248621554123003-0.Travel-Guide-Filter-Hotels)
- [Hotels near Poplar Bluff Station ](https://www.expedia.com/Poplar-Bluff-Station-Hotels.d6194576.Travel-Guide-Hotels)
- [Hotels near Mo-Ark Regional Railroad Museum ](https://www.expedia.com/Mo-Ark-Regional-Railroad-Museum-Hotels.0-l553248621554123004-0.Travel-Guide-Filter-Hotels)
- [Hotels near Black River Coliseum ](https://www.expedia.com/Black-River-Coliseum-Hotels.0-l553248635997959425-0.Travel-Guide-Filter-Hotels)
- [Hotels near Ozark Ridge Golf Course ](https://www.expedia.com/Ozark-Ridge-Golf-Course-Hotels.0-l553248621554123001-0.Travel-Guide-Filter-Hotels)
- [Hotels near Poplar Bluff Municipal ](https://www.expedia.com/Poplar-Bluff-Municipal-Airport-Hotels.0-aPOF-0.Travel-Guide-Filter-Hotels)
- [Fisk Hotels ](https://www.expedia.com/Fisk-Hotels.d553248634983120615.Travel-Guide-Hotels)
- [Hotels near Lake Wappapello ](https://www.expedia.com/Lake-Wappapello-Hotels.0-l553248621532648460-0.Travel-Guide-Filter-Hotels)
- [Qulin Hotels ](https://www.expedia.com/Qulin-Hotels.d3000349508.Travel-Guide-Hotels)
- [Cabin Rentals in Qulin ](https://www.expedia.com/Qulin-Cabins.d3000349508-aaCabins.Travel-Guide-Accommodation)
- [Cabin Rentals in Wappapello ](https://www.expedia.com/Wappapello-Cabins.d183505-aaCabins.Travel-Guide-Accommodation)
- [Wappapello Hotels ](https://www.expedia.com/Wappapello-Hotels.d183505.Travel-Guide-Hotels)
- [Motels in Wappapello ](https://www.expedia.com/Wappapello-Motels.d183505-aaMotels.Travel-Guide-Accommodation)
- [5 Star Hotels in Puxico ](https://www.expedia.com/5Star-Puxico-Hotels.s50-0-d553248634983343452.Travel-Guide-Filter-Hotels)
- [Puxico Hotels ](https://www.expedia.com/Puxico-Hotels.d553248634983343452.Travel-Guide-Hotels)
- [Oxly Hotels ](https://www.expedia.com/Oxly-Hotels.d553248635975864946.Travel-Guide-Hotels)
- [Ellsinore Hotels ](https://www.expedia.com/Ellsinore-Hotels.d553248634983439149.Travel-Guide-Hotels)
- [5 Star Hotels in Dexter ](https://www.expedia.com/5Star-Dexter-Hotels.s50-0-d55097.Travel-Guide-Filter-Hotels)
- [Dexter Hotels ](https://www.expedia.com/Dexter-Hotels.d55097.Travel-Guide-Hotels)
- [Hotels near Dexter Welcome Center Depot and Museum ](https://www.expedia.com/Dexter-Welcome-Center-Depot-And-Museum-Hotels.0-l553248621592342445-0.Travel-Guide-Filter-Hotels)
- [Cabin Rentals in Dexter ](https://www.expedia.com/Dexter-Cabins.d55097-aaCabins.Travel-Guide-Accommodation)
- [Cheap Hotels in Dexter ](https://www.expedia.com/Dexter-Hotels-Cheap-Hotels.0-0-d55097-tCheapHotels.Travel-Guide-Filter-Hotels)
- [Motels in Dexter ](https://www.expedia.com/Dexter-Motels.d55097-aaMotels.Travel-Guide-Accommodation)
- [Pet-Friendly Hotels in Dexter ](https://www.expedia.com/Dexter-Hotels-Pet-Friendly-Hotel.0-0-d55097-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)
- [Hotels with a Pool in Dexter ](https://www.expedia.com/Dexter-Hotels-Hotel-With-Pool.0-0-d55097-tHotelwithPool.Travel-Guide-Filter-Hotels)
- [Hotels with a Gym in Dexter ](https://www.expedia.com/Dexter-Hotels-Hotels-With-Fitness-Center.0-0-d55097-tHotelswithFitnessCenter.Travel-Guide-Filter-Hotels)
- [Hotels with Free Breakfast in Dexter ](https://www.expedia.com/Dexter-Hotels-Hotels-With-Complimentary-Breakfast.0-0-d55097-tHotelswithComplimentaryBreakfast.Travel-Guide-Filter-Hotels)
- [Castles in Dexter ](https://www.expedia.com/Dexter-Castles.d55097-aaCastles.Travel-Guide-Accommodation)
- [Historic Hotels in Dexter ](https://www.expedia.com/Dexter-Hotels-Historic-Hotel.0-0-d55097-tHistoricHotel.Travel-Guide-Filter-Hotels)

- [Flights from Poplar Bluff Municipal ](https://www.expedia.com/lp/airports/pof/flights-from-poplar-bluff-municipal-airport)
- [Flights from St. Louis (STL) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/stl/pof/st-louis-to-poplar-bluff)
- [Flights from Springfield (SGF) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/sgf/pof/springfield-to-poplar-bluff)
- [Flights from Memphis (MEM) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/mem/pof/memphis-to-poplar-bluff)
- [Flights from Pittsburgh (PIT) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/pit/pof/pittsburgh-to-poplar-bluff)
- [Flights from Chattanooga (CHA) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/cha/pof/chattanooga-to-poplar-bluff)
- [Flights from Los Angeles (LAX) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/lax/pof/los-angeles-to-poplar-bluff)
- [Flights from Jefferson City (JEF) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/jef/pof/jefferson-city-to-poplar-bluff)
- [Flights from Dallas (DFW) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/dfw/pof/dallas-to-poplar-bluff)
- [Flights from San Antonio (SAT) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/sat/pof/san-antonio-to-poplar-bluff)
- [Flights from New York (JFK) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/jfk/pof/new-york-to-poplar-bluff)
- [Flights from Minneapolis (MSP) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/msp/pof/minneapolis-to-poplar-bluff)
- [Flights from Raleigh (RDU) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/rdu/pof/raleigh-to-poplar-bluff)
- [Flights from Charleston (CHS) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/chs/pof/charleston-to-poplar-bluff)
- [Flights from Knoxville (TYS) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/tys/pof/knoxville-to-poplar-bluff)
- [Flights from Ontario (ONT) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/ont/pof/ontario-to-poplar-bluff)
- [Flights from San Francisco (SFO) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/sfo/pof/san-francisco-to-poplar-bluff)
- [Flights from Detroit (DTW) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/dtw/pof/detroit-to-poplar-bluff)
- [Flights from Tallahassee (TLH) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/tlh/pof/tallahassee-to-poplar-bluff)
- [Flights from Branson (BKG) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/bkg/pof/branson-to-poplar-bluff)
- [Flights from Marion (MWA) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/mwa/pof/marion-to-poplar-bluff)
- [Flights to Poplar Bluff Municipal ](https://www.expedia.com/Cheap-Flights-To-Poplar-Bluff-Municipal.d6031192.Travel-Guide-Flights)
- [Flights from Sydney (SYD) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/syd/pof/sydney-to-poplar-bluff)
- [Hopscotch Air Orlando (MCO) to Poplar Bluff (POF) flights ](https://www.expedia.com/lp/flight-routes/hopscotch-air-from-orlando-intl-to-poplar-bluff-municipal/o2/mco/pof)
- [Hopscotch Air Milwaukee (MKE) to Poplar Bluff (POF) flights ](https://www.expedia.com/lp/flight-routes/hopscotch-air-from-general-mitchell-intl-to-poplar-bluff-municipal/o2/mke/pof)
- [Flights from London (LON) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/lon/pof/london-to-poplar-bluff)
- [Flights from Alexandria (AEX) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/aex/pof/alexandria-to-poplar-bluff)
- [Flights from Champaign (CMI) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/cmi/pof/champaign-to-poplar-bluff)
- [Flights from Singapore (SIN) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/sin/pof/singapore-to-poplar-bluff)
- [Flights from Sikeston (SIK) to Poplar Bluff (POF) ](https://www.expedia.com/lp/flights/sik/pof/sikeston-to-poplar-bluff)
- [Flights from Fisk ](https://www.expedia.com/lp/flights/553248634983120615/flights-from-fisk)
- [Flights from Qulin ](https://www.expedia.com/lp/flights/3000349508/flights-from-qulin)
- [Flights to Wappapello ](https://www.expedia.com/Cheap-Flights-To-Wappapello.d183505.Travel-Guide-Flights)
- [Flights from Wappapello ](https://www.expedia.com/lp/flights/183505/flights-from-wappapello)
- [Flights from Ellsinore ](https://www.expedia.com/lp/flights/553248634983439149/flights-from-ellsinore)
- [Flights to Dexter ](https://www.expedia.com/Cheap-Flights-To-Dexter.d55097.Travel-Guide-Flights)
- [Flights from Dexter ](https://www.expedia.com/lp/flights/55097/flights-from-dexter)
- [Orlando to Dexter ](https://www.expedia.com/lp/flights/178294/55097/orlando-to-dexter)

- [Margaret Harwell Art Museum ](https://www.expedia.com/Margaret-Harwell-Art-Museum-Poplar-Bluff.d553248621554123003.Vacation-Attraction)
- [Mo-Ark Regional Railroad Museum ](https://www.expedia.com/Mo-Ark-Regional-Railroad-Museum-Poplar-Bluff.d553248621554123004.Vacation-Attraction)
- [Black River Coliseum ](https://www.expedia.com/Black-River-Coliseum-Poplar-Bluff.d553248635997959425.Vacation-Attraction)
- [Hydro Adventures ](https://www.expedia.com/Hydro-Adventures-Poplar-Bluff.d553248635997958816.Vacation-Attraction)
- [Ozark Ridge Golf Course ](https://www.expedia.com/Ozark-Ridge-Golf-Course-Poplar-Bluff.d553248621554123001.Vacation-Attraction)
- [Lake Wappapello ](https://www.expedia.com/Lake-Wappapello-Wappapello.d553248621532648460.Vacation-Attraction)
- [Visit Qulin ](https://www.expedia.com/Qulin.dx3000349508)
- [Visit Wappapello ](https://www.expedia.com/Wappapello.dx183505)
- [The Heritage House ](https://www.expedia.com/The-Heritage-House-Dexter.d553248621592342444.Vacation-Attraction)
- [Dexter Welcome Center Depot and Museum ](https://www.expedia.com/Dexter-Welcome-Center-Depot-And-Museum-Dexter.d553248621592342445.Vacation-Attraction)
- [Visit Dexter ](https://www.expedia.com/Dexter.dx55097)
- [Dexter Vacations ](https://www.expedia.com/Dexter.d55097.Destination-Travel-Guides)

- [Car rental Poplar Bluff Airport (POF) ](https://www.expedia.com/Car-Rentals-In-Poplar-Bluff-Municipal.d6031192.Car-Rental-Guide)
- [Car rentals near Fisk ](https://www.expedia.com/Car-Rentals-In-Fisk.d553248634983120615.Car-Rental-Guide)
- [Car rentals near Lake Wappapello ](https://www.expedia.com/Car-Rentals-In-Lake-Wappapello.d553248621532648460.Car-Rental-Guide)
- [Car rentals near Qulin ](https://www.expedia.com/Car-Rentals-In-Qulin.d3000349508.Car-Rental-Guide)
- [Car rentals near Wappapello ](https://www.expedia.com/Car-Rentals-In-Wappapello.d183505.Car-Rental-Guide)
- [Car rentals near Neelyville ](https://www.expedia.com/Car-Rentals-In-Neelyville.d553248634983269231.Car-Rental-Guide)
- [Car rentals near Williamsville ](https://www.expedia.com/Car-Rentals-In-Williamsville.d553248634983506457.Car-Rental-Guide)
- [Car rentals near Fagus ](https://www.expedia.com/Car-Rentals-In-Fagus.d553248635975846879.Car-Rental-Guide)
- [Car rentals near Puxico ](https://www.expedia.com/Car-Rentals-In-Puxico.d553248634983343452.Car-Rental-Guide)
- [Car rentals near Ellsinore ](https://www.expedia.com/Car-Rentals-In-Ellsinore.d553248634983439149.Car-Rental-Guide)
- [Car rentals near Dexter ](https://www.expedia.com/Car-Rentals-In-Dexter.d55097.Car-Rental-Guide)
- [Hertz Rental Cars in Dexter ](https://www.expedia.com/Hertz-Car-Rentals-In-Dexter.d55097-c40.Car-Rental-Guide-Suppliers)
- [Auto Rent Rental Cars in Dexter ](https://www.expedia.com/Auto-Rent-Car-Rentals-In-Dexter.d55097-c1006.Car-Rental-Guide-Suppliers)
- [Right-Cars Rental Cars in Dexter ](https://www.expedia.com/Right-Cars-Car-Rentals-In-Dexter.d55097-c1102.Car-Rental-Guide-Suppliers)
- [Avis Rental Cars in Dexter ](https://www.expedia.com/Avis-Car-Rentals-In-Dexter.d55097-c41.Car-Rental-Guide-Suppliers)
- [Enterprise Rental Cars in Dexter ](https://www.expedia.com/Enterprise-Car-Rentals-In-Dexter.d55097-c15.Car-Rental-Guide-Suppliers)
- [Standard Car Rentals in Dexter ](https://www.expedia.com/Standard-Car-Rentals-In-Dexter.d55097-tStandard.Car-Rental-Guide-Class)
- [Alamo Rent A Car Rental Cars in Dexter ](https://www.expedia.com/Alamo-Rent-A-Car-Car-Rentals-In-Dexter.d55097-c6.Car-Rental-Guide-Suppliers)

- [Wappapello Vacation Rentals ](https://www.expedia.com/Wappapello-Vacation-Rentals.d183505.Travel-Guide-VacationRentals)
- [Dexter Vacation Rentals ](https://www.expedia.com/Dexter-Vacation-Rentals.d55097.Travel-Guide-VacationRentals)