Find 5 Star Hotels in Palo Alto, CA from $148

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Our top choices for Palo Alto 5-star hotels

Shashi Hotel Mountain View Palo Alto

Shashi Hotel Mountain View Palo Alto
5.0 star property
Mountain View
9.4 out of 10, Exceptional, (1193)
"Perfect place to stay and enjoy "
United States
Ali
$134 nightly
The price is $148
Jan 5 - Jan 6, 2026
Total with taxes and fees
Shashi Hotel Mountain View Palo Alto

Four Seasons Hotel Silicon Valley at East Palo Alto

Four Seasons Hotel Silicon Valley at East Palo Alto
5.0 star property
East Palo Alto
9.4 out of 10, Exceptional, (666)
"Wonderful stay "
United States
Cindy
$360 nightly
The price is $409
Jan 2 - Jan 3, 2026
Total with taxes and fees
Four Seasons Hotel Silicon Valley at East Palo Alto

Rosewood Sand Hill

Rosewood Sand Hill
5.0 star property
Menlo Park
9.4 out of 10, Exceptional, (276)
"Really great hotel and my go to place for anything in Palo Alto "
United States
Lisa
$861 nightly
The price is $973
Dec 26 - Dec 27
Total with taxes and fees
Rosewood Sand Hill

Nobu Hotel Palo Alto

Nobu Hotel Palo Alto
5.0 star property
University South
9.2 out of 10, Wonderful, (434)
"Beautiful hotel. "
United States
Dianne
$395 nightly
The price is $457
Dec 22 - Dec 23
Total with taxes and fees
Nobu Hotel Palo Alto

Clement Palo Alto – All-Inclusive Urban Resort

Clement Palo Alto – All-Inclusive Urban Resort
5.0 star property
Palo Alto
10.0 out of 10, Exceptional, (112)
"Great hotel!!"
United States
Matthew
$720 nightly
The price is $833
Dec 17 - Dec 18
Total with taxes and fees
Clement Palo Alto – All-Inclusive Urban Resort
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Palo Alto

Silicon Valley's heart offers visitors the chance to tour Stanford's iconic campus and stroll University Avenue's tech-inspired shops. Bike the flat, tree-lined neighborhoods where garage startups became tech giants, then hike the rolling hills of Foothills Park when you need a break.

F688EF PALO ALTO, USA - OCT 22 2014

Top Palo Alto Hotel Reviews

Find out more about Palo Alto

Ready for an incredible adventure? Add further luxury on your next trip to Palo Alto by treating yourself to the best of the best when it comes to lodging. It's an ideal fusion. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Palo Alto so popular in the last year. There's no reason to delay a getaway to Palo Alto any longer. Furthermore, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. Our 5-star hotels in Palo Alto are the perfect places to relax in during your next getaway. Don't wait any longer!

5-Star Hotels in Palo Alto

Don't be afraid to be pampered during your trip, along with pristine rooms. Top-notch customer care, granite-tiled bathrooms, and fabulous spa offerings are waiting for you. You're sure to find exactly the accommodation you need. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What creature comforts do you want in your lodging? A concierge to help you make reservations at that outstanding restaurant? A full-body massage to help your cares fall away? High thread-count sheets, lip-smacking main courses, and even spectacular views...these hotels will leave you amazed.

Can't wait to get outside? Don't worry. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Palo Alto are the perfect place to relax after an exciting day. Ready to learn more? Then explore the 487 reviews various guests have left on Expedia and get to know these places.

Make Your Escape

The results are in, and Palo Alto 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. This is a great time to find 5-star hotel deals in @region! It's time to indulge yourself. Select one of our Palo Alto 5-star hotels today and soothe yourself in complete comfort tomorrow.

Frequently asked questions

What are the best 5-star hotels in Palo Alto?
According to Expedia traveler reviews, Nobu Hotel Palo Alto, Clement Palo Alto – All-Inclusive Urban Resort and Four Seasons Hotel Silicon Valley at East Palo Alto are among the leading 5-star hotels in Palo Alto. Offering best-in-class amenities and impeccable service, you can expect a luxurious and memorable stay.
How much does it cost to stay in a 5-star hotel in Palo Alto?
You can find a range of pricing options for a 5-star hotel in Palo Alto on Expedia. How much you'll pay will depend on when you want to travel, trip length and other factors. Compare available accommodations for your chosen dates and use our pricing and other filters to discover the ideal luxury stay.

  • Search for the lowest price per night from $170

What makes a hotel 5 stars in Palo Alto?
In Palo Alto, a hotel needs to provide a certain amount of high-end amenities to be rated 5 stars. These may include gourmet restaurants, saunas and spas, on-site gyms, premium bedding, complimentary luxury toiletries and more. What also sets 5-star hotels apart is their guest-focused service. You can look forward to things like concierge services, nightly turn-down services and in-room massage. Some may also offer thoughtful touches such as a welcome gift.

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