Amazonia Vacations from $229

Book a Hotel + Flight or Car together to unlock savings

Your Amazonia Vacation

With an Amazonia vacation package, you can forget about planning stresses and instead focus on experiencing what this wonderful destination has on offer. Why not organize your trip to Amazonia around a few of its top cities? Florencia, San Jose del Guaviare and La Macarena all make wonderful places to begin. Expedia is your one-stop shop for organizing your Amazonia vacation. From accommodations and flights, to car rentals and activities, we know how to curate a travel experience like no other.

The Latest Amazonia vacation packages

Price found within the past 48 hours. Click for updated prices.
Cabañas Ecológicas Mu'ü
Reserva Natural Yavary Tucano
Kurupira Cabin Floating
WAIRA SUITES HOTEL
hotel paraiso salvaje
Don't see what you're looking for?
See all available trips from Columbus to Amazonia
View all trips

Discover the most popular places to visit in Amazonia

Amazonia Hotel Deals

Hotel Anaconda

Hotel Anaconda

3 out of 5
Carrera 11 7-34, Leticia, Amazonas
Fully refundableReserve now, pay when you stay
8/10 Very Good! (130 reviews)
"Having the travel agency in the same building was fantastic, people were very nice."

Reviewed on May 28, 2025

Hotel Anaconda
Hotel Amazon by On Vacation

Hotel Amazon by On Vacation

3 out of 5
Vereda San Jose, Leticia, Amazonas
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $123 total per night from Aug 26 to Aug 27
$123 total
Aug 26 - Aug 27
6.4/10 (39 reviews)
"Nice Place to disconnect, beautiful view of the Amazon river, Nature sounds all day around. Keep in mind that there is jot Cellphone reception due to the Hotel location. you can pay for WiFi approximately $3 to 4 dollars for 6 hours only and you can only use Whatsapp for messaging and audio calls ..."

Reviewed on Jul 27, 2023

Hotel Amazon by On Vacation
Decameron Decalodge Ticuna

Decameron Decalodge Ticuna

3.5 out of 5
Dir: Cra 11 No. 6-11, Leticia, Amazonas
9.2/10 Wonderful! (57 reviews)
"I loved Leticia and the tour options to see and explore the jungle, the river and all surroundings. We will be back for sure. Visiting 3 countries in one place is amazing."

Reviewed on Aug 2, 2025

Decameron Decalodge Ticuna
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More vacations you might like

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.