Santa Fe de Antioquia Vacations from $401

Book a Hotel + Flight or Car together to unlock savings

Photo by Tahino2000

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to $1,045 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Your Santa Fe de Antioquia Vacation

Lock in a Santa Fe de Antioquia vacation package and get set to experience all this city has to offer. Think about staying in the neighborhood of Zona Colonial, which is great for shopping, history and bars and pubs. Make your trip to Santa Fe de Antioquia even more fulfilling by including some sightseeing. Bridge of the West, Cathedral of Santa Fe de Antioquia and Iglesia de Santa Bárbara are some of the popular attractions worth exploring. Stop daydreaming and start doing. Browse the many options on Expedia today and put your Santa Fe de Antioquia vacation plans into action!

The Latest Santa Fe de Antioquia vacation packages

Price found within the past 48 hours. Click for updated prices.
Autenthico Provenza Hotel Medellin

Autenthico Provenza Hotel Medellin

3 out of 5
El Poblado
Save 100% on your flight
Price was $644, price is now $401 per person
$401
per person
Nov 27 - Dec 2
found 6 hours ago
Roundtrip flight included
Fort Lauderdale (FLL) to Medellín (MDE)
8.4/10 Very Good! (5 reviews)
EP Casa Uribe Architecture Art & Nature

EP Casa Uribe Architecture Art & Nature

4 out of 5
El Poblado
Save 100% on your flight
Price was $2,991, price is now $1,730 per person
$1,730
per person
Dec 14 - Dec 17
found 1 day ago
Roundtrip non-stop flight included
Fort Lauderdale (FLL) to Medellín (MDE)
10/10 Exceptional! (3 reviews)
The house is extremely comfortable and spacious. Luxury amenities that made us feel at home. The pool, jacuzzi and sauna. Graciela the house keeper and Charles our private chef made our stay amazing. It was nice that they had a lunch and dinner menu available for those days we wanted to stay in. Probably one of the best stays in Medellin. The location is just minutes away from Provenza and surroundings. Manuela the host was super attentive, helping us with reservations at restaurants.

Reviewed on Mar 24, 2025

Hotel Estadio Real

Hotel Estadio Real

3 out of 5
Laureles - Estadio
Save 100% on your flight
Price was $1,122, price is now $662 per person
$662
per person
Nov 30 - Dec 7
found 1 day ago
Roundtrip flight included
San Juan (SJU) to Medellín (MDE)
6/10 (29 reviews)
Instalaciones excelentes, desayuno muy rico y la atencion 100/10

Reviewed on Oct 16, 2024

Sonata 44 Hotel Laureles

Sonata 44 Hotel Laureles

3 out of 5
Laureles
Price was $1,919, price is now $1,139 per person
$1,139
per person
Dec 25 - Jan 1
found 1 day ago
Roundtrip non-stop flight included
New York (JFK) to Medellín (MDE)
9/10 Wonderful! (54 reviews)
Excellent service and very clean.

Reviewed on Sep 18, 2024

Cannúa Lodge

Cannúa Lodge

4 out of 5
Save 100% on your flight
Price was $1,916, price is now $1,184 per person
$1,184
per person
Dec 29 - Jan 3
found 1 day ago
Roundtrip flight included
Fort Lauderdale (FLL) to Medellín (MDE)
9/10 Wonderful! (30 reviews)
Amazing nature reserve. Five star food quality! Responsive staff.

Reviewed on Sep 17, 2025

Don't see what you're looking for?
See all available trips from Columbus to Santa Fe de Antioquia
View all trips

Discover the most popular places to visit in Santa Fe de Antioquia

Longest bridge in South America during the 19th century

Bridge of the West

After visiting Bridge of the West, make a plan to see the other sights and activities in Santa Fe de Antioquia. Make time to visit the cathedral and monuments while you're in the area.

Bridge of the West
Santa Fe

Bolivar Square

4.5/5(8 reviews)

Learn about the local history of Santa Fe de Antioquia with a stop at Bolivar Square. Stroll along the riverfront or experience the area's festivals.

Bolivar Square

Casa Atanasio Girardot

You can spend an afternoon browsing the exhibits at Casa Atanasio Girardot during your trip to Santa Fe de Antioquia.

Casa Atanasio Girardot

What to do in Santa Fe de Antioquia

Tour Santa Fe De Antioquia

Tour Santa Fe De Antioquia

$245
per traveler
Tour Santa Fe De Antioquia
"3 plans in 1: Coffee tour in Medellín's mountains, private villa with pool, and visit to the colonial town of Santa Fe de Antioquia(national heritage), and Occidente hanging bridg

Medellín Coffee Tour in Mountains and Santa Fe Colonial with Pool

$230
per adult
Medellín Coffee Tour in Mountains and Santa Fe Colonial with Pool
See all activities in Santa Fe de Antioquia

Santa Fe de Antioquia Hotel Deals

Arde La Selva

Arde La Selva

4 out of 5
km 1 via anza vereda obregon, Santa Fe de Antioquia, Antioquia
Fully refundableReserve now, pay when you stay
$136 nightly
The price is $136 total per night from Oct 15 to Oct 16
$136 total
Oct 15 - Oct 16
9.8/10 Exceptional! (14 reviews)
"Everything at Arde la Selva was amazing, the staff is super friendly, food and drinks are great, the premises are really comfortable, pools are great, but ... the music is unnecessarily loud. I understand the afternoons and evenings are more vibrant, but having loud music from 8 am to 12 m prevents ..."

Reviewed on Sep 2, 2025

Arde La Selva
Hotel Boutique Al Alma

Hotel Boutique Al Alma

4.5 out of 5
#9-50 Cra. 8, Santa Fe de Antioquia, Antioquia
$85 nightly
The price is $85 total per night from Oct 13 to Oct 14
$85 total
Oct 13 - Oct 14
9.4/10 Exceptional! (47 reviews)
"El hotel muy bien ubicado, preciosas las instalaciones (coloniales), muy rico el desayuno, la habitación cómoda, pero se sentía el sonido de la música y las conversaciones de las personas que estaban en el lobby. El servicio muy bueno."

Reviewed on Sep 28, 2025

Hotel Boutique Al Alma
Hotel Mariscal Robledo

Hotel Mariscal Robledo

3 out of 5
Cra 12 No 9 70, Santa Fe de Antioquia, Antioquia
$109 nightly
The price is $109 total per night from Oct 30 to Oct 31
$109 total
Oct 30 - Oct 31
9.2/10 Wonderful! (218 reviews)
"Unique hotel full of antiques, great coffee shop and Sunday buffet breakfast delicious with many choices. Pool area very nice with many comfortable shaded and non shaded beds. Location to town square is one minute!"

Reviewed on Sep 29, 2025

Hotel Mariscal Robledo
See all 487 properties in Santa Fe de Antioquia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santa Fe de Antioquia Essential Information

Language
Spanish
Currency
Colombian pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Enrique Olaya Herrera Airport (EOH)
Population
11,800
Max Temp Winter
70ºF
Max Temp Summer
75ºF
Top Sights
Cathedral of Santa Fe de Antioquia, Museo Juan del Corral and San Jeronimo Park

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Santa Fe de Antioquia vacation package cost?
Offering excellent value package deals from $401 on Expedia, you'll be thrilled with how little a vacation to Santa Fe de Antioquia costs! Our packages mean less travel planning for you and greater savings.
What are the cheapest months to go to Santa Fe de Antioquia?
You can generally find lower rates and better availability in June, July and October. Explore our cheap Santa Fe de Antioquia vacation packages and you could get some excellent off-season deals.
How many days is enough for Santa Fe de Antioquia?
Generally, a handful of days is great for a Santa Fe de Antioquia vacation. With a well-planned itinerary, you can check out all the leading attractions such as Bridge of the West, as well as explore some hidden gems along the way.
Is it worth booking a vacation package to Santa Fe de Antioquia?
Boasting a host of highlights starting with its excellent history, Santa Fe de Antioquia is a good vacation destination. Whether you'd like to check out sights such as Bridge of the West and Cathedral of Santa Fe de Antioquia or take the path less traveled, you'll have loads to see and do on your Santa Fe de Antioquia vacation.
How to find the best Santa Fe de Antioquia package deals?
Use Expedia's filters to help you find some unbeatable Santa Fe de Antioquia package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your adventure for midweek, or browse for Santa Fe de Antioquia package deals in the off-season. Switch up your travel dates and you may score even bigger discounts. As a rule of thumb, it's usually best to lock in your vacation package as soon as possible.
Is it cheaper to book a Santa Fe de Antioquia vacation as a package?
Expedia vacation packages are designed to help you keep more money in your pocket. Bundle your flight, hotel and car rental into one great-value price and you could save hundreds of dollars. You'll typically land a better deal than booking each component individually. And you'll still have the flexibility to create a customized Santa Fe de Antioquia vacation by choosing your preferred type of stay, airline and car class.
When to book a vacation package to Santa Fe de Antioquia?
Land incredible bargains by reserving your flights ahead of time with Expedia. If spontaneity is more your style, grab one of our last-minute deals for a spur-of-the-moment Santa Fe de Antioquia escape.
How to plan a trip to Santa Fe de Antioquia?

  1. Choose your dates: The things you'd like to do in Santa Fe de Antioquia and your favorite season will help you decide when to travel.
  2. Figure out your budget: Ensure you have enough money to pay for everything from food and transportation to activities and airfares. Your accommodations will probably be the largest expense during your trip to Santa Fe de Antioquia.
  3. Discover Santa Fe de Antioquia using our trip planning tool: Gain insights into the leading attractions and best properties for your trip to Santa Fe de Antioquia. You can also save your favorite places, collaborate with family and friends and manage your plans in one place.
  4. Set the duration of your trip: Start by listing all the activities and sights you want to experience in Santa Fe de Antioquia. Then, estimate how long you'll need at each, as well as any travel time.
  5. Bundle your hotel and flights: Epic destination, check. Length of stay, check. All that's left now is to find a Santa Fe de Antioquia vacation package that brings all your bookings together.
  6. Book experiences or activities ahead of time: Whether it's a ticket to a major attraction or a day trip, you won't have to worry about missing out on Santa Fe de Antioquia's highlights. Find all the incredible things to do in Santa Fe de Antioquia in Santa Fe de Antioquia with our dedicated travel guide.

Does Expedia offer Book Now, Pay Later Santa Fe de Antioquia vacation packages?
Your Santa Fe de Antioquia trip should be an escape from your daily routine, not a reason for money worries. So to give you more flexibility, we've teamed up with online lender Affirm to offer you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and spread the cost over 3, 6 or 12 months. Plus, there aren't any hidden costs or late payment fees to worry about.

Explore a world of travel with Expedia

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.