Santa Fe de Antioquia Vacations from $326

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Your Santa Fe de Antioquia Vacation

Lock in a Santa Fe de Antioquia vacation package and get set to experience all this city has to offer. Think about staying in the neighborhood of Zona Colonial, which is great for shopping, history and bars and pubs. Make your trip to Santa Fe de Antioquia even more fulfilling by including some sightseeing. Bridge of the West, Cathedral of Santa Fe de Antioquia and Iglesia de Santa Bárbara are some of the popular attractions worth exploring. Stop daydreaming and start doing. Browse the many options on Expedia today and put your Santa Fe de Antioquia vacation plans into action!

The Latest Santa Fe de Antioquia vacation packages

Price found within the past 48 hours. Click for updated prices.
EcoHotel Montenegro

EcoHotel Montenegro

3 out of 5
Save 100% on your flight
Price was $569, price is now $326 per person
$326
per person
Oct 22 - Oct 29
found 1 day ago
Roundtrip non-stop flight included
San Juan (SJU) to Medellín (MDE)
8.8/10 Excellent! (8 reviews)
El personal del hotel es súper amable, nos pareció muy organizado, limpio y bonito. Le puse 4 estrellas porque no hay agua caliente y en el cuarto el ventilador hace mucho ruido. Pero recomendado para un plan familiar de descanso

Reviewed on Jun 30, 2025

Cannúa Lodge

Cannúa Lodge

4 out of 5
Save 100% on your flight
Price was $1,021, price is now $532 per person
$532
per person
Sep 23 - Sep 30
found 1 day ago
Roundtrip non-stop flight included
San Juan (SJU) to Medellín (MDE)
9/10 Wonderful! (30 reviews)
Great way to get away fom the hustle of daily life. Enjoyed time with my family (including 2 kids). the staff is excellent. food is great!

Reviewed on Mar 24, 2025

Cardinal Glamping

Cardinal Glamping

3.5 out of 5
Save 100% on your flight
Price was $641, price is now $347 per person
$347
per person
Oct 26 - Nov 1
found 1 day ago
Roundtrip non-stop flight included
San Juan (SJU) to Medellín (MDE)
No reviews
Tau House

Tau House

3 out of 5
Save 100% on your flight
Price was $1,310, price is now $712 per person
$712
per person
Sep 23 - Sep 30
found 1 day ago
Roundtrip non-stop flight included
San Juan (SJU) to Medellín (MDE)
9.4/10 Exceptional! (94 reviews)
Very nice hotel, relaxing ,clean,excellent food and service

Reviewed on Aug 17, 2025

EP Casa Uribe Architecture Art & Nature

EP Casa Uribe Architecture Art & Nature

4 out of 5
El Poblado
Save 100% on your flight
Price was $3,195, price is now $1,754 per person
$1,754
per person
Sep 21 - Sep 25
found 12 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Medellín (MDE)
10/10 Exceptional! (1 review)
The house is extremely comfortable and spacious. Luxury amenities that made us feel at home. The pool, jacuzzi and sauna. Graciela the house keeper and Charles our private chef made our stay amazing. It was nice that they had a lunch and dinner menu available for those days we wanted to stay in. Probably one of the best stays in Medellin. The location is just minutes away from Provenza and surroundings. Manuela the host was super attentive, helping us with reservations at restaurants.

Reviewed on Mar 24, 2025

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Discover the most popular places to visit in Santa Fe de Antioquia

Longest bridge in South America during the 19th century

Bridge of the West

After visiting Bridge of the West, make a plan to see the other sights and activities in Santa Fe de Antioquia. Make time to visit the cathedral and monuments while you're in the area.

Bridge of the West
Santa Fe

Bolivar Square

Learn about the local history of Santa Fe de Antioquia with a stop at Bolivar Square. Stroll along the riverfront or experience the area's festivals.

Bolivar Square

Casa Atanasio Girardot

You can spend an afternoon browsing the exhibits at Casa Atanasio Girardot during your trip to Santa Fe de Antioquia.

Casa Atanasio Girardot

What to do in Santa Fe de Antioquia

Tour Santa Fe De Antioquia

Tour Santa Fe De Antioquia

$245
per traveler
Tour Santa Fe De Antioquia
"3 plans in 1: Coffee tour in Medellín's mountains, private villa with pool, and visit to the colonial town of Santa Fe de Antioquia(national heritage), and Occidente hanging bridg

Medellín Coffee Tour in Mountains and Santa Fe Colonial with Pool

$230
per adult
Medellín Coffee Tour in Mountains and Santa Fe Colonial with Pool
See all activities in Santa Fe de Antioquia

Santa Fe de Antioquia Hotel Deals

Arde La Selva

Arde La Selva

4 out of 5
km 1 via anza vereda obregon, Santa Fe de Antioquia, Antioquia
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $148 total per night from Aug 25 to Aug 26
$148 total
Aug 25 - Aug 26
9.6/10 Exceptional! (13 reviews)
"Arde La Selva in Santa Fe de Antioquia is an absolute gem! The stunning grounds, surrounded by lush nature and nestled next to the river, create a serene and breathtaking atmosphere. The pool is perfect for relaxation, and the music adds just the right touch of ambiance. But what truly sets Arde ..."

Reviewed on Jul 27, 2025

Arde La Selva
Hotel Boutique Al Alma

Hotel Boutique Al Alma

4.5 out of 5
#9-50 Cra. 8, Santa Fe de Antioquia, Antioquia
9.4/10 Exceptional! (42 reviews)

Reviewed on Aug 10, 2025

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Hotel Boutique Al Alma
Hotel Mariscal Robledo

Hotel Mariscal Robledo

3 out of 5
Cra 12 No 9 70, Santa Fe de Antioquia, Antioquia
$105 nightly
The price is $105 total per night from Aug 21 to Aug 22
$105 total
Aug 21 - Aug 22
9.2/10 Wonderful! (214 reviews)
"Excellent place to rest to hang out. Overall service was good, the staff is very polite. Easy to walk around town, the town is lovely. Right outside the hotel there are locals vendors with typical food and artisanal products. The road from Medellin to Santa Fe de Antioquia is excellent, its about ..."

Reviewed on Aug 12, 2025

Hotel Mariscal Robledo
See all 484 properties in Santa Fe de Antioquia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

How much does a Santa Fe de Antioquia vacation package cost?
Offering excellent value package deals from $326 on Expedia, you'll be thrilled with how little a vacation to Santa Fe de Antioquia costs! Our packages mean less travel planning for you and greater savings.
What are the cheapest months to go to Santa Fe de Antioquia?
You can generally find lower rates and better availability in June, July and October. Explore our cheap Santa Fe de Antioquia vacation packages and you could get some excellent off-season deals.
How many days is enough for Santa Fe de Antioquia?
Generally, a handful of days is great for a Santa Fe de Antioquia vacation. With a well-planned itinerary, you can check out all the leading attractions such as Bridge of the West, as well as explore some hidden gems along the way.
Is it worth booking a vacation package to Santa Fe de Antioquia?
Boasting a host of highlights starting with its excellent history, Santa Fe de Antioquia is a good vacation destination. Whether you'd like to check out sights such as Bridge of the West and Cathedral of Santa Fe de Antioquia or take the path less traveled, you'll have loads to see and do on your Santa Fe de Antioquia vacation.
How to find the best Santa Fe de Antioquia package deals?
Use Expedia's filters to help you find some unbeatable Santa Fe de Antioquia package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your adventure for midweek, or browse for Santa Fe de Antioquia package deals in the off-season. Switch up your travel dates and you may score even bigger discounts. As a rule of thumb, it's usually best to lock in your vacation package as soon as possible.
Is it cheaper to book a Santa Fe de Antioquia vacation as a package?
Expedia vacation packages are designed to help you keep more money in your pocket. Bundle your flight, hotel and car rental into one great-value price and you could save hundreds of dollars. You'll typically land a better deal than booking each component individually. And you'll still have the flexibility to create a customized Santa Fe de Antioquia vacation by choosing your preferred type of stay, airline and car class.
When to book a vacation package to Santa Fe de Antioquia?
Land incredible bargains by reserving your flights ahead of time with Expedia. If spontaneity is more your style, grab one of our last-minute deals for a spur-of-the-moment Santa Fe de Antioquia escape.
How to plan a trip to Santa Fe de Antioquia?

  1. Choose your dates: The things you'd like to do in Santa Fe de Antioquia and your favorite season will help you decide when to travel.
  2. Figure out your budget: Ensure you have enough money to pay for everything from food and transportation to activities and airfares. Your accommodations will probably be the largest expense during your trip to Santa Fe de Antioquia.
  3. Discover Santa Fe de Antioquia using our trip planning tool: Gain insights into the leading attractions and best properties for your trip to Santa Fe de Antioquia. You can also save your favorite places, collaborate with family and friends and manage your plans in one place.
  4. Set the duration of your trip: Start by listing all the activities and sights you want to experience in Santa Fe de Antioquia. Then, estimate how long you'll need at each, as well as any travel time.
  5. Bundle your hotel and flights: Epic destination, check. Length of stay, check. All that's left now is to find a Santa Fe de Antioquia vacation package that brings all your bookings together.
  6. Book experiences or activities ahead of time: Whether it's a ticket to a major attraction or a day trip, you won't have to worry about missing out on Santa Fe de Antioquia's highlights. Find all the incredible things to do in Santa Fe de Antioquia in Santa Fe de Antioquia with our dedicated travel guide.

Does Expedia offer Book Now, Pay Later Santa Fe de Antioquia vacation packages?
Your Santa Fe de Antioquia trip should be an escape from your daily routine, not a reason for money worries. So to give you more flexibility, we've teamed up with online lender Affirm to offer you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and spread the cost over 3, 6 or 12 months. Plus, there aren't any hidden costs or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.