The Best Hotels Closest to Biomuseo in Panama City for 2026

A modern building with colorful geometric shapes and a clear blue sky.

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Our top choices for Biomuseo hotels

A spacious indoor courtyard with tiled flooring, multiple seating areas, and hanging plants.

A room with a large window, a television mounted on the wall, and two chairs.

A four-poster bed with a black and white bedspread, two bedside tables with lamps, and a robe hanging on a rack.

An open door revealing a balcony with a wrought iron railing, potted plants, and a window with a curtain.

1. La Isabela Suites

San Felipe, 1.5 mi from Biomuseo

Gabriela

$137 nightly

$153 total

Oct 7 - Oct 8

Total with taxes and fees

A multi-story building with ornate balconies, large windows, and decorative moldings.

A spacious restaurant with high wooden ceilings, multiple tables and chairs, and a bar area with shelves of bottles and glasses.

A room with a white sofa, a wooden chair, a mirror, and a large window with curtains.

A luxurious room with ornate chandeliers, a large mirror, and a bar area with shelves of bottles.

2. Hotel Plaza Herrera

San Felipe, 1.5 mi from Biomuseo

Christina

$196 nightly

$217 total

Sep 7 - Sep 8

Total with taxes and fees

A balcony with a table, chairs, and a view of a city skyline across a body of water.

A hotel with a rooftop pool, lounge chairs, and a view of the sea.

A spacious lobby with a round coffee table, seating areas, and a large wall clock.

A spacious lobby with high ceilings, modern furniture, and decorative lighting fixtures.

3. Sofitel Legend Casco Viejo, Panama City

San Felipe, 1.6 mi from Biomuseo

Jose

$385 nightly

$424 total

Sep 8 - Sep 9

Total with taxes and fees

A restaurant with multiple dining tables, chairs, and a central water feature.

A modern living room with a sofa, a coffee table, and a TV mounted on the wall.

A rooftop terrace with tables and chairs, a view of two white towers, and a building with a large window.

A historic building with ornate stonework and a balcony with plants.

4. Hotel La Compañía Casco Antiguo

San Felipe, 1.5 mi from Biomuseo

Reid

$339 nightly

$373 total

Sep 14 - Sep 15

Total with taxes and fees

A restaurant interior with checkered flooring, wooden tables, wicker chairs, and hanging wicker lamps.

A multi-level interior with a checkered floor, wooden railings, and potted plants.

A rooftop terrace with a hot tub, wooden deck, outdoor seating, and a view of a cityscape including a clock tower.

A room with a brick wall, a wooden staircase, and hanging pendant lights.

5. Amarla Boutique Hotel Casco Viejo Adults Only

San Felipe, 1.6 mi from Biomuseo

Kennedi

$203 nightly

$228 total

Oct 7 - Oct 8

Total with taxes and fees

A grand, illuminated building with a symmetrical facade, multiple balconies, and a prominent entrance.

A glass of white wine on a balcony railing overlooking a city street with buildings and cars.

A restaurant interior with a large indoor tree, tables, chairs, and a display of potted plants.

A spacious bedroom with a large bed, a chandelier, a bathroom with a bathtub, and a dining area.

6. La Concordia Boutique Hotel

San Felipe, 1.5 mi from Biomuseo

Shrinand

$204 nightly

$224 total

Sep 14 - Sep 15

Total with taxes and fees

A spacious outdoor patio with wicker furniture, potted plants, and umbrellas providing shade.

A modern hotel lobby with beige sofas, marble flooring, and a reception desk.

A dimly lit restaurant with wooden decor, tables, and chairs arranged for dining.

A modern bar area with wooden bar stools, a black countertop, and a display of wine bottles.

7. Hotel San Felipe

San Felipe, 1.5 mi from Biomuseo

ORLANDO RICARDO

$142 nightly

$157 total

Oct 1 - Oct 2

Total with taxes and fees

A multi-story building with balconies, large windows, and a clear blue sky.

A hotel room with a brick wall, a large window with curtains, a bed with pillows, a nightstand, and a chair.

An outdoor patio with a white umbrella, lounge chairs, and a tiled floor.

A hallway with a brick wall, a blue door, and a chair with a cushion.

8. Las Clementinas

San Felipe, 1.6 mi from Biomuseo

James

$146 nightly

$161 total

Sep 16 - Sep 17

Total with taxes and fees

A spacious indoor area with high ceilings, large windows, and multiple dining tables.

A restaurant with brick walls, arched windows, and a variety of seating arrangements including tables and chairs.

A white building with multiple balconies, large windows, and decorative railings.

A spacious lobby with a tiled floor, large windows, and potted plants.

9. American Trade Hotel

San Felipe, 1.5 mi from Biomuseo

James

$181 nightly

$199 total

Sep 13 - Sep 14

Total with taxes and fees

A hotel room with a bed, a desk with a computer, a chair, a mirror, and a staircase.

A spacious living area with a staircase leading to a loft, a large mirror, and a television.

A spacious living area with a staircase leading to a second floor, a sofa, a TV, and a dining area.

10. Hotel Bardot Boutique

San Felipe, 1.6 mi from Biomuseo

justin

$84 nightly

$92 total

Sep 15 - Sep 16

Total with taxes and fees

A spacious living room with blue sofas, a marble coffee table, and framed pictures on the walls.

A bedroom with a large bed, white walls, and a view of a building through arched windows.

A hotel room with a large bed, a TV, a balcony with a view of the outside, and a window with decorative ironwork.

11. Hotel Magnolia Boutique

San Felipe, 1.5 mi from Biomuseo

Boris

$74 nightly

$82 total

Sep 8 - Sep 9

Total with taxes and fees

A modern indoor pool area with clear blue water, lounge chairs, and a wall of plants.

A modern bedroom with a large window, a bed with white linens, a nightstand, and a painting on the wall.

A modern kitchen with a central island, stainless steel appliances, and a dining area with black chairs.

A balcony with a view of the sea, a table with a vase and a candle, and a chair.

12. Casco View Apartments

Santa Ana, 1.5 mi from Biomuseo

chris

$83 nightly

$91 total

Sep 8 - Sep 9

Total with taxes and fees

A multi-story building with balconies, arched windows, and decorative railings.

A spacious lobby with a wooden staircase, multiple seating areas, and a reception desk.

A building with a balcony and a street view.

A rooftop swimming pool with lounge chairs, potted plants, and a view of a city skyline including a prominent building with a dome.

13. Central Hotel Panama Casco Viejo

San Felipe, 1.5 mi from Biomuseo

Olga

$183 nightly

$202 total

Oct 6 - Oct 7

Total with taxes and fees

A modern bathroom with a glass shower enclosure, a herringbone wooden floor, and a stone wall feature.

A multi-story building with balconies adorned with string lights, a sign reading "ZABAH", and a storefront named "CORCHO".

A compact kitchen with a dining area, including a coffee maker, sink, and wooden chairs.

14. Corcho

San Felipe, 1.5 mi from Biomuseo

Ashley

$82 nightly

$90 total

Sep 12 - Sep 13

Total with taxes and fees

A rooftop bar with a city skyline view, outdoor seating, and a bar area with bottles and glasses.

A restaurant interior with tables and chairs, decorative hanging lights, and a mural on the wall.

A hotel room with a large bed, a painting on the wall, a door, and a small table with a lamp.

A modern living room with a purple wall, two abstract paintings, a white sofa with colorful cushions, a wooden coffee table with books and bottles, and patterned floor tiles.

15. Tantalo Hotel

San Felipe, 1.6 mi from Biomuseo

David

$99 nightly

$109 total

Sep 13 - Sep 14

Total with taxes and fees

An outdoor patio area with wicker furniture and glass-top tables, surrounded by lush greenery and a view of the interior.

A living room with wicker furniture, a television, and a sliding glass door leading to a balcony with plants.

A rectangular swimming pool with a tiled edge, surrounded by a tiled patio area.

A hotel room with a bed, a ceiling fan, a TV, a refrigerator, and a window with curtains.

16. The Balboa Inn

Balboa, 1.7 mi from Biomuseo

Jan

$70 nightly

$77 total

Sep 11 - Sep 12

Total with taxes and fees

A resort with a pool area, lounge chairs, and a view of a bridge at night.

A hotel room with a bed, a TV on a wooden cabinet, a nightstand with a lamp, and a view of the outdoors through a glass door.

A reception desk with three staff members, a green patterned wall, a wooden reception area, and a large plant.

A formal dining area with round tables, white tablecloths, and blue lace borders.

17. Radisson Hotel Panama Canal

Amador, 0.9 mi from Biomuseo

Samantha

$90 nightly

$100 total

Sep 8 - Sep 9

Total with taxes and fees

A balcony with a view of a cityscape, including a river and a bridge.

A bedroom with a sloped ceiling, a bed with white bedding, a small wooden drying rack, a patterned rug, and an air conditioning unit.

A high-rise building with a glass elevator shaft, a metal railing on the balcony, and a sign with the letters "OASIS".

A spacious living area with a patterned rug, a round ottoman, a sofa, and a coffee table. There is a door leading to another room and a wall-mounted security camera.

18. Oasis Hotel

San Felipe, 1.6 mi from Biomuseo

Gregg

$52 nightly

$58 total

Oct 7 - Oct 8

Total with taxes and fees

A modern bedroom with a large bed, a bedside table, a wall-mounted air conditioner, and a window with curtains.

A compact kitchen with dark wooden cabinets, a black refrigerator, a coffee maker, and a dining table with chairs.

A narrow hallway with a black wicker chair, a small table with a potted plant, and a bed in the background.

A modern kitchen with a dining area, a bed, and a view of the outdoors.

19. La Palma Experience

Amador, 0.7 mi from Biomuseo

Shuntaro

$72 nightly

$79 total

Oct 6 - Oct 7

Total with taxes and fees

A balcony with a view of a marina and a hilly landscape.

A couple in white robes on a bed with a champagne bottle and ice bucket.

A modern building with a large metallic sculpture in the foreground, surrounded by palm trees and a clear blue sky.

A couple seated on wicker chairs with a view of a body of water and greenery in the background.

20. The Beach House

Amador, 1.6 mi from Biomuseo

Darwin

$77 nightly

$85 total

Sep 7 - Sep 8

Total with taxes and fees

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Compare popular hotels close to Biomuseo

Property	Star rating	Guest rating
La Isabela Suites	9.8 Exceptional 210 reviews	View
Hotel Plaza Herrera	9.8 Exceptional 47 reviews	View
Sofitel Legend Casco Viejo, Panama City	9.8 Exceptional 740 reviews	View
Hotel La Compañía Casco Antiguo	9.8 Exceptional 348 reviews	View
Amarla Boutique Hotel Casco Viejo Adults Only	9.6 Exceptional 142 reviews	View

Top Biomuseo Hotel Reviews

Sofitel Legend Casco Viejo, Panama City

10/10 Excellent

"A fantastic location in old town, with outstanding service."

Hotel Riu Plaza Panama

10/10 Excellent

"Magnificent breakfast!! Very close to Santuario Nacional de Panama❤️"

Central Hotel Panama Casco Viejo

10/10 Excellent

"Clean rooms, great breakfast. Great air conditioning, small small pool. Great location. Friendly staff.. lots to do near by. Stairs and elevators"

Hotel Casa Panamá

10/10 Excellent

"All good for my needs"

Radisson Hotel Panama Canal

8/10 Good

"It was a nice getaway if you didn't want to be directly in the city"

Hotel Caracas - Casco Viejo

8/10 Good

"great staff"

Casa Love by Wynwood House

10/10 Excellent

"The unit we stayed in was large and fully equipped, with a balcony and a full kitchen. The building was secure and conveniently located within walking distance to everything in casco viejo. There are lots of shops and restaurants nearby and we felt mostly safe walking around. The only issue we had was that the code to our lockbox didn’t work when we arrived. However, we texted the property staff and they were able to give us another code that worked right away. The internet in the unit worked fine, but be sure to have a data plan or eSIM so that you can connect with the property and order Ubers, especially when you first get in, as the WiFi in the airport can be very spotty."

Casa La Costa By Wynwood House

10/10 Excellent

"Very nice place, clean and big, location is very good to walk around restaurants."

w* | Inviting 2BR w/ Fantastic View in Panama

10/10 Excellent

"Amazing apartment in the edge of the old city, with windows and a balcony facing the sea. Don't be put off by comments about the neighborhood. We found everybody friendly and helpful. Close walk to all the sites in the Cosco, as well as the fish, meat and veggie markets. Perfectly equipped for making many of our own meals Comfortable. A great find!"

Other attractions near Biomuseo

Amador Causeway

9.0/10 (1,902 reviews)

You can learn about the history of Ancon with a stop at Amador Causeway. Stroll along the seaside or visit the shops in this vibrant area.

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Amador Convention Center

9.2/10 (23 reviews)

Learn about the events happening at Amador Convention Center during your trip to Ancon. While in this walkable area, you can savor the top-notch restaurants.

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Punta Culebra Nature Center

9.0/10 (14 reviews)

Enjoy an outing to Punta Culebra Nature Center during your stay in Ancon. Stroll along the seaside in this vibrant area, or check out its top-notch restaurants.

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Maracana Stadium

8.0/10 (32 reviews)

Catch an event at Maracana Stadium during your trip to Panama City. Check out the shops and top-notch restaurants in this vibrant area.

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Smithsonian Tropical Research Institute Punta Culebra

9.2/10 (19 reviews)

You can spend time browsing the exhibits at Smithsonian Tropical Research Institute Punta Culebra in Ancon. Amble around this vibrant area's seaside and enjoy its top-notch restaurants.

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Danilo Perez Foundation

Explore the campus of Danilo Perez Foundation as part of your travels around Panama City. Check out the shops and top-notch restaurants in this vibrant area.

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Plaza de Francia

10.0/10 (1 review)

You can learn about the history of Panama City when you stop by Plaza de Francia. Check out the shops and top-notch restaurants in this vibrant area.

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Mola Museum

You can spend time browsing the exhibits at Mola Museum during your trip to Panama City. You can enjoy the bars while in the area.

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Frequently asked questions

What's the area like around Biomuseo?

Biomuseo is located in a vibrant area of Ancon known for its array of dining options and major shopping area. You'll find 1273 hotels and other accommodations within a few miles for a convenient home base.

What's the best hotel to stay near Biomuseo?

Radisson Hotel Panama Canal is one of the top choices for your stay based on our traveler data, and this hotel offers 2 outdoor pools and 2 restaurants. It's located just a short 0.9 mi (1.5 km) from Biomuseo. Another good choice is La Palma Experience, located just 0.7 mi (1.1 km) away.

How many hotels will I be able to find near Biomuseo?

Expedia has 1273 hotels and other accommodations a few miles from Biomuseo.

If I need to cancel the hotel reservation for my stay near Biomuseo, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to get the best options available near Biomuseo.

Where can I learn more about changing or cancelling my trip in the area near Biomuseo?

For more information about updating your stay near Biomuseo or cancelling it, click here.

What can I see and do near Biomuseo?

Interoceanic Canal Museum, Mola Museum, and Museum of History Panama feature a variety of fascinating exhibits to see while you're in town. Sights like Panama Canal Railway, Iglesia del Carmen, and Paseo de Las Bovedas are must-sees while exploring the area. You can catch a show at Anita Villalaz Theater, Amador Theater, and National Theater.

Find hotels near Biomuseo, Panama City from $58

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Our top choices for Biomuseo hotels

1. La Isabela Suites

2. Hotel Plaza Herrera

3. Sofitel Legend Casco Viejo, Panama City

4. Hotel La Compañía Casco Antiguo

5. Amarla Boutique Hotel Casco Viejo Adults Only

6. La Concordia Boutique Hotel

7. Hotel San Felipe

8. Las Clementinas

9. American Trade Hotel

10. Hotel Bardot Boutique

11. Hotel Magnolia Boutique

12. Casco View Apartments

13. Central Hotel Panama Casco Viejo

14. Corcho

15. Tantalo Hotel

16. The Balboa Inn

17. Radisson Hotel Panama Canal

18. Oasis Hotel

19. La Palma Experience

20. The Beach House

Compare popular hotels close to Biomuseo

Top Biomuseo Hotel Reviews

Sofitel Legend Casco Viejo, Panama City

Hotel Riu Plaza Panama

Central Hotel Panama Casco Viejo

Hotel Casa Panamá

Radisson Hotel Panama Canal

Hotel Caracas - Casco Viejo

Casa Love by Wynwood House

Casa La Costa By Wynwood House

w* | Inviting 2BR w/ Fantastic View in Panama

Other attractions near Biomuseo

Amador Causeway

Amador Convention Center

Punta Culebra Nature Center

Maracana Stadium

Smithsonian Tropical Research Institute Punta Culebra

Danilo Perez Foundation

Plaza de Francia

Mola Museum

Frequently asked questions