Cairo is home to Quality Inn Cairo I-57. The area's natural beauty can be seen at Mississippi River and Shawnee National Forest. Visit our Cairo travel guide
13201 Kessler Road, Cairo, IL, 62914
What's nearby
Mound City National Cemetery
6 min drive - 6.7 miles
Fort Defiance State Park
9 min drive - 6.1 miles
City of Miner Convention Center
22 min drive - 31.4 miles
Ballard Wildlife Management Area
26 min drive - 15.2 miles
Sikeston Depot Museum
27 min drive - 34.2 miles
Getting around
Paducah, KY (PAH-Barkley Regional)
43 min drive
Restaurants
Shemwells BBQ
7 min drive
Nu Diner
8 min drive
Sneed's Cafe
17 min walk
Twenty Eighth Street Tavern
6 min drive
Mound's Sandwich Shop & Arcade
11 min drive
About this property
Quality Inn Cairo I-57
Property highlights
Quality Inn Cairo I-57 provides free full breakfast and more. Stay connected with free in-room WiFi.
You'll also enjoy the following perks during your stay:
Free self parking
RV/bus/truck parking, a 24-hour front desk, and coffee/tea in the lobby
Free newspapers
Room features
All guestrooms at Quality Inn Cairo I-57 offer comforts such as air conditioning, as well as amenities like free WiFi and free weekday newspapers.
Yes, this hotel allows dogs (limit 1 total). There's a deposit of USD 20 per stay and a fee of USD 15 per pet, per night. A cleaning fee of USD 25 also applies. Service animals are exempt from fees. Some restrictions may apply, so please contact the property for more details.
How much does it cost to stay at Quality Inn Cairo I-57?
As of Oct 23, 2026, prices found for a 1-night stay for 2 adults at Quality Inn Cairo I-57 on Nov 13, 2026 start from $76, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.
How much is parking?
Self parking is free at this property.
What time is check-in at Quality Inn Cairo I-57?
Check-in start time: 3 PM; Check-in end time: 3:30 AM. Late check-in is available during limited hours.
What time is check-out at Quality Inn Cairo I-57?
Check-out is at 11 AM.
Where is Quality Inn Cairo I-57 located?
Situated in Cairo, this hotel is 2.3 mi (3.6 km) from Mississippi River and within 6 mi (10 km) of Ohio River Valley and Mound City National Cemetery. Fort Defiance State Park and Shawnee National Forest are also within 9 mi (15 km).
Can I cancel my reservation for free and receive a full refund?
Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.
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Reviews
Quality Inn Cairo I-57 Reviews
6.4
All reviews shown are from real guest experiences. Only travelers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
The room was very clean and the breakfast was pretty good. No complaints
Stayed 1 night in May 2024
Verified review
6/10 Okay
Joe
Nov 3, 2024
Liked: Cleanliness, staff & service
Rooms were clean and without pests. The staff was nice. It has a quiet little seating area with a grill. The location is the setback. Cairo is an abandoned town with almost any restaurants, etc
There are very few places to stay in Cairo. The Quality Inn is pretty good considering that the town is not in good shape. The room was large, quiet and clean but aging. The receptionists were very friendly and helpful. The property is convenient for a visit to Fort Defiance. We were satisfied with this stay.
Good bang for your buck! Price through the app was on point and $25 less than going through the hotel..Room was clean zero complaints on cleanliness except for the carpet that you could feel moisture in which also made the hallway and rooms smell..Get rid of the carpet and put down laminate and I’m pretty sure the smell would go away!
Stayed 1 night in May 2024
Verified review
8/10 Good
Kathy
Apr 14, 2024
Liked: Cleanliness, staff & service
Much better than average breakfast, scrambled eggs, sausage gravy & waffles, in addition to usual. Very rundown neighborhood. Pile of dirty laundry in hall.
The staff in the office were the best part of our stay. However, the area around the hotel was run down, abandoned buildings everywhere, and the road to get to the hotel was full of potholes, borken glass everywhere, and the hotel itself looked to be the only building within it's vicinity that was in working condition. Neither my husband nor I slept. I asked for a refund so we could go to a safer location, but I didnt purchase the travel insurance. I would NOT recommend!
Outdated, but clean could have made up for that. The bed was comfortable. The tub was stained with what appeared to be grout and filth. There were also whitish drips all over the brown doorframes. The mirror was definitely cleaned with the previous tenant’s dirty towels. The coffee condiments were incomplete and hadn’t been replaced. And if all the above wasn’t enough, the place is in a true ghost town!
I always like to stay off the beat and path. Generally speaking it’s quite a bit quieter and calmer. This hotel was older obviously. It had one of those old heat lamps in the bathroom from the 1970’s. Brought a blast from the past. It was very clean which is most important to me. It did have usb ports for charging. I have portable ones tha I always take not every place has them. It was quiet and comfortable. Not too much room sanitizer.
The web site said smoking rooms, this is untrue. I was fine with that, but my room smelled like a smoking room. There where cobwebs on the lamps and the tables where dirty. The shower was dirty and had a whole in the ceiling. The outside was very dirty. I would never stay at this hotel aging. I would tell everyone to stay far away from it as they can.
Dirty microwave and coffee maker, missing bulb in bathroom, blown bulb above sink, hole in the wall where an outlet must have been, towels were clean but had a smell of being in storage. Very dated interior but functional. God enough to sleep for one evening.
Television in my room did not get any signal for being able to view any channels. Shower was horrible. Towel rack was broken with a handwritten sign to “Do Not Use”. Lobby was dead bolted in the morning so I couldn’t get any complimentary breakfast or coffee that was supposed to be included in the room rate. Will avoid this place in the future.