4/5 - Good
Verified traveler
Due to the coronavirus, we didn't really have an opportunity to check out Cape Girardeau, visiting with friends in their home instead. Next time though!
Cape Girardeau, MO
Travel Guide
Visit Cape Girardeau
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
$90 nightly
The price is $102 total per night from Dec 18 to Dec 19
$102 total
Dec 18 - Dec 19
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,000 reviews)
Beds were great. Very clean all around. Very nice breakfast with glutten free bread for my wife.
Reviewed on Dec 8, 2025
The Riverview
777 Main St Cape Girardeau MO
$96 nightly
The price is $109 total per night from Dec 15 to Dec 16
$109 total
Dec 15 - Dec 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau ...
9.2/10 Wonderful! (470 reviews)
Didn’t eat breakfast
Reviewed on Dec 11, 2025
Courtyard by Marriott Cape Girardeau Downtown
400 Broadway St. Cape Girardeau MO
$116 nightly
The price is $131 total per night from Dec 23 to Dec 24
$131 total
Dec 23 - Dec 24
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
9.4/10 Exceptional! (468 reviews)
We had a great stay, the hotel is nice and clean. The staff was very friendly and welcoming!
Reviewed on Dec 1, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Little Blue Cottage on Spanish
Cape Girardeau MO
Stay at this vacation home in Cape Girardeau. Popular attractions eDen Spa & Salon and The Glenn House are located nearby.
8.4/10 Very Good! (45 reviews)
The amenities were in pretty strange conditions. Not non functional. Just strange. Fairly priced. I would stay again
Reviewed on Oct 30, 2025
The Twisted Sassafras Treehouse
Cape Girardeau MO
Stay at this cabin in Cape Girardeau. Enjoy a garden, patios, and an in-room coffeemaker. Popular attractions Cape Girardeau Conservation Nature Center and Cape ...
10/10 Exceptional! (27 reviews)
This is the perfect private romantic getaway! We had such a blast here. Definitely recommend!
Reviewed on Nov 2, 2025
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
Cape Girardeau MO
Stay at this apartment in Cape Girardeau. Enjoy free WiFi, a garden, and in-room jetted tubs. Popular attractions eDen Spa & Salon and Riverfront Park are located ...
9.4/10 Exceptional! (44 reviews)
Loved the vibe of the place. Beds were super comfy!
Reviewed on Nov 10, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Southeast Missouri State University
4.5/5(76 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.
Isle Casino Cape Girardeau
4.5/5(48 reviews)
Why not roll the dice with a visit to Isle Casino Cape Girardeau during your travels in Cape Girardeau? While in this family-friendly area, you can savor the top-notch restaurants.
Show Me Center
Catch an event at Show Me Center during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.
Saint Francis Medical Center
Though Saint Francis Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of Cape Girardeau while you are here.
Southeast Missouri Hospital
Though Southeast Missouri Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Cape Girardeau while you are here.
Riverfront Park
Riverfront Park is just one of the places to see in Cape Girardeau, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savor the top-notch restaurants.
Reviews of Cape Girardeau
4.3
Top Destination
5/5 - Excellent
Verified traveler
We appreciated the close proximity of dining options enabling us to walk rather than getting back in the car after a long travel day.
3/5 - Okay
Verified traveler
I live here. Reason for the hotel was so my daughter could swim with her friends. And have a small birthday pool party and get out of the house for a night
5/5 - Excellent
Verified traveler
Just loved it all, the people,place's it was just wonderful..
5/5 - Excellent
Verified traveler
Love this city. Go see the bridge over into IL - beautiful!!! The city is a very pleasant place to visit.
4/5 - Good
Verified traveler
I really enjoyed the Missouri Wall of Fame.
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- Southeast Missouri State University
- Isle Casino Cape Girardeau
- Riverfront Park
- Riverfront Bridge Park
- Hunter Valley Winery
- Cape Splash Family Aquatic Center
- Lazy L Safari Park
- Cape Girardeau Conservation Nature Center
- Cape Rock Park
- eDen Spa & Salon
- Fort D Historic Site
- Mississippi River
- Shawnee National Forest
- Trail of Tears State Park
