Find Resorts & Hotels with Spas in Charleston, MO

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Top Charleston Resorts & Hotels with Spas

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1003)
"It was right off the interstate with lots of restaurant options "
$95 nightly
The price is $107
Oct 19 - Oct 20
Total with taxes and fees
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Charleston

Find out more about Charleston

Top Charleston attractions for a relaxing vacation

Travelers seeking hotels with spas in Charleston, Missouri, will find a charming blend of relaxation and exploration. Begin your journey at the nearby Mississippi River, where you can enjoy scenic boat rides or tranquil picnics along the riverbank, perfect for unwinding before or after a spa day. Don’t miss a visit to the historic downtown area, where you can stroll through quaint shops, indulge in local cuisine, and discover the rich history of the region. Nature enthusiasts will appreciate the nearby Trail of Tears State Park, offering hiking trails that showcase stunning views of the landscape, ideal for a refreshing outdoor adventure. After a day of exploration, retreat to a spa hotel that not only pampers with soothing treatments but also provides easy access to these attractions. The convenience of staying in a centrally located hotel allows for a seamless blend of relaxation and adventure, ensuring that your family enjoys both pampering and quality time together. Charleston's welcoming atmosphere and attentive hospitality are sure to meet the high expectations of any Quality Seeker.

Top Charleston Hotel Reviews

Frequently asked questions

Looking for a spa hotel in Charleston?
Treat yourself to some time in a luxurious spa hotel and you won't regret it. Check out the opera and restaurants in Charleston—your day trip starts here. Be sure to pay a visit to the churches during your stay. Hotels with spas are the perfect way to break out of your routine and add a layer of luxury to your vacation.
What's there to see and do in Charleston?
Experience all that Charleston has to offer when you visit Mississippi River, Ohio River, and Columbus-Belmont State Park. If you have a bit of extra time while you're in the area, you might want to check out Central Park and Big Oak Tree State Park.
What is a Charleston spa hotel?
Spa hotels in Charleston provide lodging and have an on-site spa offering services like facials and body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.

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