Title: Panacea, FL Car Rental - Free Cancellation Options - Expedia.com [Panacea Travel Guide](https://expedia.com/Panacea.dx3000431554)[Hotels in Panacea](https://expedia.com/Panacea-Hotels.d3000431554.Travel-Guide-Hotels)[Flights to Panacea](https://expedia.com/Cheap-Flights-To-Panacea.d3000431554.Travel-Guide-Flights)[Panacea Vacation Packages](https://expedia.com/Panacea.d3000431554.Destination-Travel-Guides) ![](https://images.trvl-media.com/place/3000431554/ef7510fd-7401-44b7-8add-0b033672a2ae.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # $41 Car Rental Panacea, FL ## Search and Compare from Car Companies in Panacea ## Featured car rental suppliers Compare from agencies ![car suppliers logo](https://forever.travel-assets.com/flex/flexmanager/images/2022/02/16/car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car rentals - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car rentals [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Top Car Deals in Panacea \* Price found within the past 6 days. Click for updated prices. Sun, Feb 15 - Mon, Feb 16 ### Midsize SUV Kia Sorrento or similar - 5 people - Unlimited mileage ![Rent-A-Wreck](//mediaim.expedia.com/cars/logos/RW.png) Tallahassee, Florida, USA ![Kia Sorrento](//mediaim.expedia.com/cars/33/5c2b665b-8c5c-4c7d-b322-a28a2f7762cf.jpg) #### $41 includes taxes & fees $23 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=30.435800&olon=-84.353540&date1=2/15/2026&date2=2/16/2026&pprfrr=23.00&tprfrr=40.92&cvrfrr=RW&ctrfrr=IF&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22suv%22]) Sun, Feb 15 - Mon, Feb 16 ### Compact Chevrolet Sonic or similar - 5 people - Unlimited mileage ![Rent-A-Wreck](//mediaim.expedia.com/cars/logos/RW.png) Tallahassee, Florida, USA ![Chevrolet Sonic](//mediaim.expedia.com/cars/33/f9e5b3b5-4ea4-4ac2-a0e0-ae567e46f5e9.jpg) #### $42 includes taxes & fees $24 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=30.435800&olon=-84.353540&date1=2/15/2026&date2=2/16/2026&pprfrr=23.81&tprfrr=41.94&cvrfrr=RW&ctrfrr=CC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22compact%22]) Sun, Feb 15 - Mon, Feb 16 ### Economy Chevrolet Spark or similar - 4 people - Unlimited mileage ![Rent-A-Wreck](//mediaim.expedia.com/cars/logos/RW.png) Tallahassee, Florida, USA ![Chevrolet Spark](//mediaim.expedia.com/cars/33/c30eeecb-be9e-4673-9115-f344a075169d.jpg) #### $42 includes taxes & fees $24 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=30.435800&olon=-84.353540&date1=2/15/2026&date2=2/16/2026&pprfrr=23.81&tprfrr=41.94&cvrfrr=RW&ctrfrr=EC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22economy%22]) Sun, Feb 15 - Mon, Feb 16 ### Fullsize Toyota Camry or similar - 5 people - Unlimited mileage ![Rent-A-Wreck](//mediaim.expedia.com/cars/logos/RW.png) Tallahassee, Florida, USA ![Toyota Camry](//mediaim.expedia.com/cars/33/1e5fb154-1092-4943-a0b0-0612c6caa052.jpg) #### $46 includes taxes & fees $27 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=30.435800&olon=-84.353540&date1=2/15/2026&date2=2/16/2026&pprfrr=27.11&tprfrr=46.05&cvrfrr=RW&ctrfrr=FC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22fullsize%22]) Sun, Feb 15 - Mon, Feb 16 ### Standard Hyundai Venue or similar - 5 people - Unlimited mileage ![Rent-A-Wreck](//mediaim.expedia.com/cars/logos/RW.png) Tallahassee, Florida, USA ![Hyundai Venue](//mediaim.expedia.com/cars/33/e6ddc3cb-1098-4e94-a5ce-ce5c23594a0e.jpg) #### $55 includes taxes & fees $34 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=30.435800&olon=-84.353540&date1=2/15/2026&date2=2/16/2026&pprfrr=34.25&tprfrr=54.96&cvrfrr=RW&ctrfrr=SC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22standard%22]) Sun, Feb 15 - Mon, Feb 16 ### Special Manager's Special or similar - 5 people - Unlimited mileage ![Rent-A-Wreck](//mediaim.expedia.com/cars/logos/RW.png) Tallahassee, Florida, USA ![Manager's Special](//mediaim.expedia.com/cars/33/37f05fb4-d4eb-42a5-924f-44b2f96f5aab.jpg) #### $64 includes taxes & fees $42 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=30.435800&olon=-84.353540&date1=2/15/2026&date2=2/16/2026&pprfrr=41.56&tprfrr=64.07&cvrfrr=RW&ctrfrr=XX&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22other%22]) Sun, Feb 15 - Mon, Feb 16 ### Mini Van Dodge Grand Caravan or similar - 5 people - Unlimited mileage ![Rent-A-Wreck](//mediaim.expedia.com/cars/logos/RW.png) Tallahassee, Florida, USA ![Dodge Grand Caravan](//mediaim.expedia.com/cars/33/c16959b2-11c6-4ee7-a10d-b3bc67371097.jpg) #### $77 includes taxes & fees $52 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=30.435800&olon=-84.353540&date1=2/15/2026&date2=2/16/2026&pprfrr=51.80&tprfrr=76.84&cvrfrr=RW&ctrfrr=MV&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22minivan%22]) Sun, Feb 15 - Mon, Feb 16 ### Midsize Elite Telsa Short Range Model 3 or similar - 5 people - Unlimited mileage ![Budget](//mediaim.expedia.com/cars/logos/ZD.png) Tallahassee, Florida, USA ![Telsa Short Range Model 3](//mediaim.expedia.com/cars/39/cdea7be4-fba3-47a5-a509-0bc2297220b8.jpg) #### $82 includes taxes & fees $59 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=30.395741&olon=-84.345467&date1=2/15/2026&date2=2/16/2026&pprfrr=58.99&tprfrr=81.82&cvrfrr=ZD&ctrfrr=JC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22midsize%22]) Sun, Feb 15 - Mon, Feb 16 ### Standard Elite Special Ford Mustang Mach-E or similar - 5 people - Unlimited mileage ![Budget](//mediaim.expedia.com/cars/logos/ZD.png) Tallahassee, Florida, USA ![Ford Mustang Mach-E](//mediaim.expedia.com/cars/39/9eb70d2f-e3e7-4e36-9e24-1505e077c35a.jpg) #### $91 includes taxes & fees $67 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=30.395741&olon=-84.345467&date1=2/15/2026&date2=2/16/2026&pprfrr=66.99&tprfrr=91.38&cvrfrr=ZD&ctrfrr=RX&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22standard%22]) Fri, Feb 13 - Sat, Feb 14 ### Premium Dodge Charger or similar - 5 people - Unlimited mileage ![Priceless Car Rental](//mediaim.expedia.com/cars/logos/PR.png) Tallahassee, Florida, USA ![Dodge Charger](//mediaim.expedia.com/cars/1060/f5231c9d-139b-4d8d-bd7d-bd9c8dce2b6e.jpg) #### $78 includes taxes & fees $78 per day found 17 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=30.435800&olon=-84.353500&date1=2/13/2026&date2=2/14/2026&pprfrr=77.56&tprfrr=77.56&cvrfrr=PR&ctrfrr=PC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22premium%22]) Thu, Feb 12 - Fri, Feb 13 ### Luxury Chrysler 300 or similar - 5 people - Unlimited mileage ![Rent-A-Wreck](//mediaim.expedia.com/cars/logos/RW.png) Tallahassee, Florida, USA ![Chrysler 300](//mediaim.expedia.com/cars/33/ccb0ec1d-5ca8-4548-9c6d-4503d81ec855.jpg) #### $111 includes taxes & fees $79 per day found 7 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=30.435800&olon=-84.353540&date1=2/12/2026&date2=2/13/2026&pprfrr=79.10&tprfrr=110.88&cvrfrr=RW&ctrfrr=LC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22luxury%22]) Sun, Feb 15 - Mon, Feb 16 ### Premium Elite SUV Audi Q5 or similar - 5 people - Unlimited mileage ![Alamo](//mediaim.expedia.com/cars/logos/AL.png) TALLAHASSEE, USA ![Audi Q5](//mediaim.expedia.com/cars/6/a50a8a7e-784a-4c22-8177-72ad55f9ebc4.jpg) #### $118 includes taxes & fees $90 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=30.397720&olon=-84.347780&date1=2/15/2026&date2=2/16/2026&pprfrr=89.94&tprfrr=117.96&cvrfrr=AL&ctrfrr=UF&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22suv%22]) Sun, Feb 15 - Mon, Feb 16 ### Luxury Elite Special Offer Car Maserati Quattroporte Mercedes Benz S-Class or similar - 5 people - Unlimited mileage ![Alamo](//mediaim.expedia.com/cars/logos/AL.png) TALLAHASSEE, USA ![Maserati Quattroporte Mercedes Benz S-Class](//mediaim.expedia.com/cars/6/fc2cd20f-4807-4cc9-a803-95b09a0c8954.jpg) #### $608 includes taxes & fees $500 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=30.397720&olon=-84.347780&date1=2/15/2026&date2=2/16/2026&pprfrr=499.99&tprfrr=607.74&cvrfrr=AL&ctrfrr=WZ&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22luxury%22]) ### Don't see what you're looking for? See all car rentals in Panacea [View all cars](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Panacea,%20Florida,%20United%20States%20of%20America&dpln=3000431554&date1=2/17/2026&date2=2/19/2026&crfrr=defaultFlex&SearchType=Place) Lowest prices found within the past 8 hours. Prices and availability subject to change. Additional terms may apply. ## Frequently asked questions ### How much is a rental car per day in Panacea? ### Can I rent a car from Tallahassee Intl. Airport (TLH)? ### What happens if I need to cancel my Panacea car reservation? ### Where can I go on a road trip from Panacea? > - Valdosta is around 85 miles from Panacea. Top-rated sights like Wild Adventures deserve a place on your must-see list while you're in town. > - Why not see everything on offer in Albany too? Unmissable sights in this colorful city include Radium Springs Gardens. Albany is about 110 miles from Panacea. > - Venture into the great outdoors and breathe in some fresh air at Cummer Museum of Art and Gardens. It's 160 miles from Panacea. ### How do I find the best car rental deals in Panacea with Expedia? ### How old do you have to be to rent a car in Panacea? ### What do you need to rent a car in Panacea? ### What is the cheapest car rental in Panacea? ### Can I rent a car for a month or longer in Panacea? ### Where can I find a Panacea car rental if I am younger than 25? ### What insurance should I choose for my car rental in Panacea? ## Car Rental Information | Popular car types | [SUV](https://www.expedia.com/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.com/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.com/lp/b/car-rental/economy?rfrr=car.table.Economy) | | ------------------------------------------------ | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available | | | Our best deal of the day | $41 | | Our second best deal of the day | $42 | | Our third best deal of the day | $46 | | From the airport to your hotel | [Airport Transportation](https://www.expedia.com/ground-transfers?rfrr=car.table.AirportTransportation) | | From popular domestic and international airports | [Airport Car Rentals](https://www.expedia.com/lp/b/car-rental/airport) | ## Finding the cheapest car rentals in Panacea ### **Using our Search Wizard** If the deals that are available on our page do not suit your needs, then enter Panacea into the search wizard at the top of the page. We will compare all the best deals available for your car rental in Panacea and provide you with a list of the cheapest options, with no added fees. ### **Renting a car in Panacea** Pay at pickup is available, so you don’t have to worry about spending your money until you arrive at your vehicle in Panacea. We partner with reliable partners that guarantee an enjoyable experience for solo travelers, couples, and families. Package your car with a flight or hotel to unlock even more savings from Expedia. ### **Expected prices in Panacea** Prices are subject to seasonal change depending on when you decide to arrange your car rental but right now you can book from $41. ### **Flexibility & Cancellation** Most car suppliers offer penalty-free cancellations, so you don’t have to worry about losing money if your plans change. To cancel your booking log into your account through the [Trips](https://www.expedia.com/trips) portal. Click manage booking and cancel this car. If you needed to alter your booking, then you can create a new one once you have canceled. ### **We all love being rewarded** [One Key](https://www.expedia.com/welcome-one-key?langid=1033) members save 10% or more on select hotels, cars, activities and vacation rentals. Not only that, earn OneKeyCash for every dollar spent on eligible hotels, vacation rentals, flights, car rentals, and more when you book across our family of brands: Expedia, Hotels.com and VRBO. Learn more and join today. ### **Car classes available from Expedia in 2026** The classes of vehicles available will change depending on your chosen location. - [Compact car rentals](https://www.expedia.com/lp/b/car-rental/compact) - [Convertible car rentals](https://www.expedia.com/lp/b/car-rental/convertible) - [Economy car rentals](https://www.expedia.com/lp/b/car-rental/economy) - [Fullsize car rentals](https://www.expedia.com/lp/b/car-rental/fullsize) - [Luxury car rentals](https://www.expedia.com/lp/b/car-rental/luxury) - [Midsize car rentals](https://www.expedia.com/lp/b/car-rental/midsize) - [Mini car rentals](https://www.expedia.com/lp/b/car-rental/mini) - [Minivan rentals](https://www.expedia.com/lp/b/car-rental/minivan) - [Pickup car rentals](https://www.expedia.com/lp/b/car-rental/pickup) - [Premium car rentals](https://www.expedia.com/lp/b/car-rental/premium) - [Sportscar rentals](https://www.expedia.com/lp/b/car-rental/sportscar) - [Standard car rentals](https://www.expedia.com/lp/b/car-rental/standard) - 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