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Our top choices for Panacea hotels

BOB Hotels Tallahassee - Boutique on Budget

BOB Hotels Tallahassee - Boutique on Budget
3.0 star property
Tallahassee
9.0 out of 10, Wonderful, (2,203 reviews)
"It was a great stay, friendly and helpful staff. "
United States
Michael
$75 nightly
The price is $85
May 14 - May 15
Total with taxes and fees
BOB Hotels Tallahassee - Boutique on Budget

The Panacea Motel

The Panacea Motel
2.0 star property
Panacea
9.0 out of 10, Wonderful, (169 reviews)
"Was a nice stay"
United States
Thresia
$111 nightly
The price is $124
May 13 - May 14
Total with taxes and fees
The Panacea Motel

Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites
2.5 star property
Crawfordville
8.8 out of 10, Excellent, (981 reviews)
"Clean rooms, helpful staff. One of the best places we stayed on our trip to Florida"
United States
Sean
$116 nightly
The price is $129
May 26 - May 27
Total with taxes and fees
Best Western Wakulla Inn & Suites

Hyatt House Tallahassee Capitol – University

Hyatt House Tallahassee Capitol – University
3.0 star property
Railroad Square Art District
9.0 out of 10, Wonderful, (1,660 reviews)
"Great staff and room size"
United States
Badr
$110 nightly
The price is $124
Jun 7 - Jun 8
Total with taxes and fees
Hyatt House Tallahassee Capitol – University

Wildwood Inn

Wildwood Inn
3.0 star property
Crawfordville
8.6 out of 10, Excellent, (1,016 reviews)
"Beautiful clean property "
United States
Christine
$119 nightly
The price is $132
May 26 - May 27
Total with taxes and fees
Wildwood Inn

DoubleTree by Hilton Hotel Tallahassee

DoubleTree by Hilton Hotel Tallahassee
4.0 star property
Capitol Hill
7.4 out of 10, Good, (1,008 reviews)
"Great stay!"
United States
ROBERTO
$111 nightly
The price is $125
May 14 - May 15
Total with taxes and fees
DoubleTree by Hilton Hotel Tallahassee

St James Bay Golf & Pickleball Resort

St James Bay Golf & Pickleball Resort
3.5 star property
Carrabelle
9.0 out of 10, Wonderful, (392 reviews)
"Adorable cottage. Very clean and comfortable. Check in was after hours but very easy. Will definitely stay here again. "
United States
Jennifer
$162 nightly
The price is $180
May 14 - May 15
Total with taxes and fees
St James Bay Golf & Pickleball Resort

Hotel Indigo Tallahassee - Collegetown by IHG

Hotel Indigo Tallahassee - Collegetown by IHG
3.5 star property
College Town
9.2 out of 10, Wonderful, (1,017 reviews)
"Great place and staff was excellent, very friendly."
United States
Robert
$140 nightly
The price is $158
May 17 - May 18
Total with taxes and fees
Hotel Indigo Tallahassee - Collegetown by IHG

The Lodge at Wakulla Springs

The Lodge at Wakulla Springs
3.0 star property
Crawfordville
9.4 out of 10, Exceptional, (1,007 reviews)
"Everything was excellent. "
United States
Kenneth
$104 nightly
The price is $115
May 20 - May 21
Total with taxes and fees
The Lodge at Wakulla Springs

Four Points by Sheraton Tallahassee Downtown

Four Points by Sheraton Tallahassee Downtown
3.0 star property
Governor's Walk
8.6 out of 10, Excellent, (1,129 reviews)
"Enjoyed my stay. Staff, location was everything i needed in a great stay."
United States
Todd
$102 nightly
The price is $115
Jun 7 - Jun 8
Total with taxes and fees
Four Points by Sheraton Tallahassee Downtown

Hampton Inn & Suites Tallahassee Capitol - University

Hampton Inn & Suites Tallahassee Capitol - University
2.5 star property
Railroad Square Art District
9.0 out of 10, Wonderful, (1,012 reviews)
"Very clean, quiet area. Parking easy and nice brekki 🙌🙌"
United Kingdom
Steven
$115 nightly
The price is $129
May 21 - May 22
Total with taxes and fees
Hampton Inn & Suites Tallahassee Capitol - University

Wyndham Garden Tallahassee Capitol

Wyndham Garden Tallahassee Capitol
3.0 star property
Tallahassee
5.8 out of 10, (1,243 reviews)
"The stay was agreeable, parking filled up quickly. Breakfast available each morning was a plus. Located near plenty of food locations. Had one issue in the room, the shower curtain was missing, but it was resolved rather quickly. "
United States
Natasha
$42 nightly
The price is $47
May 24 - May 25
Total with taxes and fees
Wyndham Garden Tallahassee Capitol

Holiday Inn Tallahassee E Capitol - Univ by IHG

Holiday Inn Tallahassee E Capitol - Univ by IHG
3.0 star property
Tallahassee
9.2 out of 10, Wonderful, (1,008 reviews)
"This was a nice place to stay. Friendly staff and good hot breakfast"
United States
Anthony
$91 nightly
The price is $102
May 24 - May 25
Total with taxes and fees
Holiday Inn Tallahassee E Capitol - Univ by IHG

Courtyard by Marriott Tallahassee Downtown/Capitol

Courtyard by Marriott Tallahassee Downtown/Capitol
3.0 star property
Tallahassee
8.4 out of 10, Very Good, (1,012 reviews)
"Plenty of parking, comfortable room, friendly staff "
United States
Jim
$84 nightly
The price is $94
May 17 - May 18
Total with taxes and fees
Courtyard by Marriott Tallahassee Downtown/Capitol

stayAPT Suites Tallahassee-Capitol

stayAPT Suites Tallahassee-Capitol
4.0 star property
Tallahassee
8.8 out of 10, Excellent, (107 reviews)
"Stayed with hubby on work trip. So clean and well laid out. Secured and quiet. Will def stay again!"
United States
Ines
$91 nightly
The price is $103
May 14 - May 15
Total with taxes and fees
stayAPT Suites Tallahassee-Capitol

Home2 Suites by Hilton Tallahassee State Capitol

Home2 Suites by Hilton Tallahassee State Capitol
3.0 star property
Tallahassee
8.4 out of 10, Very Good, (1,000 reviews)
"Amazing hotel and staff, close to the mall the restaurants. "
United States
Gloria
$97 nightly
The price is $109
May 24 - May 25
Total with taxes and fees
Home2 Suites by Hilton Tallahassee State Capitol

Fairfield Inn & Suites by Marriott Tallahassee Central

Fairfield Inn & Suites by Marriott Tallahassee Central
3.0 star property
Tallahassee
8.6 out of 10, Excellent, (1,002 reviews)
"Enjoyed our stay "
United States
Teena
$97 nightly
The price is $109
May 17 - May 18
Total with taxes and fees
Fairfield Inn & Suites by Marriott Tallahassee Central

Aloft Tallahassee Downtown

Aloft Tallahassee Downtown
3.0 star property
Capitol Hill
8.8 out of 10, Excellent, (1,008 reviews)
"Great place great price great staff"
United States
Kevin
$110 nightly
The price is $123
May 22 - May 23
Total with taxes and fees
Aloft Tallahassee Downtown

Hotel Duval, Autograph Collection

Hotel Duval, Autograph Collection
4.0 star property
Governor's Walk
8.0 out of 10, Very Good, (1,005 reviews)
"Clean, quiet room and excellent service and location. Wish there was more parking options."
United States
Patricia
$124 nightly
The price is $139
May 14 - May 15
Total with taxes and fees
Hotel Duval, Autograph Collection

The Old Carrabelle Hotel

The Old Carrabelle Hotel
2.0 star property
Carrabelle
9.4 out of 10, Exceptional, (25 reviews)
"Love this place"
United States
Janice Tamara
$96 nightly
The price is $106
May 14 - May 15
Total with taxes and fees
The Old Carrabelle Hotel
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Stay near popular Panacea attractions

Learn more about Panacea

Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails.

Sunset over a lake at Panacea, northern Florida, USA | NONE |

Top Panacea Hotel Reviews

More cheap stays in Panacea

Hotels in Panacea with star-rating

Find out more about Panacea

Top reasons to visit Panacea

  • Stunning Beaches: Enjoy the pristine shores along the Forgotten Coast, ideal for sunbathing and relaxation.
  • Outdoor Adventures: Explore nearby state parks offering hiking, fishing, and nature activities for outdoor enthusiasts.
  • Panacea Springs: Visit this relaxing spot for a unique blend of tranquility and adventure in the natural surroundings.
  • Charming Islands: Discover picturesque islands nearby, perfect for exploration and enjoying the coastal scenery.
  • Friendly Atmosphere: Experience the welcoming vibe of Panacea, a hidden gem inviting visitors to unwind and connect with nature.

Find great hotels near Panacea

Discover a range of delightful accommodation options in Panacea, Florida, perfect for your vacation getaway. From pet-friendly hotels to cozy guesthouses, you'll find the ideal lodging for your family adventure. Explore the best Panacea hotels that cater to travelers seeking comfort and unique experiences in this charming coastal destination.

  • Hyatt House Tallahassee Capitol – University: Hyatt House Tallahassee Capitol – University is a 3-star hotel with a guest rating of 9.0, perfect for families, business travelers, and pet owners. Located 29 miles from Panacea, this modern accommodation offers a welcoming atmosphere with amenities designed for comfort and convenience. Families will appreciate features like complimentary cribs and child-friendly safety measures, while pets are permitted with certain restrictions. Guests can enjoy spacious rooms equipped with kitchenettes, a fitness center, and a complimentary breakfast to start the day right. Its proximity to Tallahassee makes it a versatile choice for those looking to explore the area.
  • Best Western Wakulla Inn & Suites: Best Western Wakulla Inn & Suites is a budget-friendly option just 6 miles from Panacea, boasting a guest rating of 8.8. Ideal for adventure seekers and business travelers alike, this hotel offers various recreational activities nearby, including snorkeling, kayaking, and hiking. Guests can unwind in comfortable rooms and take advantage of amenities like complimentary breakfast and a pool. With its focus on outdoor activities and convenience, this hotel serves as a great base for exploring the natural beauty of Wakulla County.
  • Wildwood Inn: Wildwood Inn is a cozy 3-star hotel located 7 miles from Panacea, featuring a guest rating of 8.6. This property caters to those seeking adventure and pet-friendly accommodations. Visitors can engage in activities such as fishing, snorkeling, and sailing nearby. The inn offers comfortable lodgings with essential amenities, ensuring a pleasant stay for both guests and their furry companions. Whether you’re on a business trip or a leisurely getaway, Wildwood Inn provides a charming escape in the heart of nature.

Where to stay in Panacea

Panacea, Florida, offers a delightful blend of relaxation and adventure for every traveler. Enjoy the pristine beaches along the Forgotten Coast, perfect for sunbathing or romantic getaways. Just a short drive away, explore downtown Tallahassee for family-friendly activities and vibrant local culture. With its secluded vibe and friendly atmosphere, Panacea is a hidden gem that invites you to unwind and soak in the natural beauty of this charming coastal region.

  • Alligator Point: Nestled along the Gulf Coast, Alligator Point is a charming village that provides a perfect retreat for beach lovers and outdoor enthusiasts. With its peak travel seasons in June to July and November, visitors flock here to relish its stunning beaches and picturesque scenery. The area boasts recreational activities, including access to golf courses and resorts. Local highlights include the nearby national state park and wetlands, making it an ideal spot for nature walks and wildlife observation, ensuring a memorable travel experience.
  • Saint Teresa: A quaint village located close to Panacea, Saint Teresa is known for its inviting beaches and lush outdoor spaces. The peak travel times in March and during the summer months attract visitors seeking relaxation and adventure. Guests can enjoy recreational areas, resorts, and educational experiences. Notable attractions include the local nudist beach and the nearby national state park, providing ample opportunities for sunbathing and exploration. Saint Teresa is the perfect destination for those looking to unwind while soaking in the natural beauty of Florida’s coastline.
  • Ochlockonee Bay: This picturesque village offers a unique blend of adventure and tranquility, making it a hidden gem near Panacea. With visitor peaks in June to July and November, Ochlockonee Bay attracts those eager for outdoor experiences and stunning scenery. The area features recreational spots, educational venues, and golf opportunities. Local highlights include beautiful beaches, a national state park, and a serene lake, perfect for kayaking and fishing. Enjoy a laid-back atmosphere while discovering the natural wonders that make Ochlockonee Bay a delightful addition to your vacation itinerary.

Things to do in Panacea

Panacea, Florida, is perfect for beach and outdoor enthusiasts, offering stunning scenery and recreational activities. Visitors can explore various recreational areas and enjoy educational experiences at local resorts. Whether you're looking to relax on the beach or engage in outdoor adventures, Panacea has something for everyone, making it an ideal vacation spot.

Shopping

In the heart of Panacea, you can explore local shops for unique gifts and souvenirs. For more extensive options, if you're up for a drive, head to the nearby shopping malls like the Tallahassee Mall or Governor's Square Mall, both offering a variety of stores to satisfy your shopping needs.

Recreation

In Panacea, the Gulf Specimen Marine Lab offers unique eco-tours that connect you with nature, while the nearby Wakulla Springs State Park invites you to relax with scenic hiking and swimming. For a holistic experience, check out local wellness centers offering yoga classes and rejuvenating spa treatments.

Adventure

Experience the beauty of the Gulf of Mexico with kayaking or paddleboarding at the scenic Panacea Waterfront Park. For an adrenaline rush, explore the nearby Wakulla Springs State Park for thrilling hiking trails and wildlife spotting, making for an adventurous day in nature.

Nightlife

Experience the laid-back vibe of Panacea with a visit to The Blue Parrot, where you can enjoy live music and tasty seafood. For a more relaxed evening, grab a drink at the nearby St. Teresa Beach, perfect for watching the sunset over the water.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Panacea

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Panacea are July and December to January, where the prices are slightly lower. This is in comparison to May and September to October, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Panacea is Monday. The most expensive day to stay in Panacea is Friday.
  • Find cheap hotels on Expedia: You can utilize Expedia's search tool to tailor your options based on your budget, preferred location, and desired hotel type. To find the best prices and deals, simply arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel stay in Panacea with your flights and activities through an Expedia package deal.

Find the best attractions in Panacea

Panacea, Florida, is a delightful destination for beach lovers and outdoor enthusiasts, offering stunning scenery and various attractions. You'll find beautiful beaches, the nearby state parks, and charming islands to explore. Key points of interest include Panacea Springs and the surrounding area, perfect for those seeking a relaxing and adventurous getaway. Whether you're looking to soak up the sun or enjoy nature, Panacea has something for everyone.

  • Alligator Point Beach: Enjoy the laid-back beach vibes at Alligator Point Beach, a serene spot perfect for sunbathing, swimming, and beachcombing. With soft sands and gentle waves, it’s an ideal location for relaxation and family fun.
  • Bald Point State Park: Experience stunning scenery and outdoor adventures at Bald Point State Park. Explore scenic trails, spot diverse wildlife, and enjoy activities like hiking, fishing, and kayaking amidst beautiful coastal landscapes.
  • USS Mohawk CGC Veterans Memorial Reef: Dive into history at the USS Mohawk CGC Veterans Memorial Reef, a unique underwater attraction. This artificial reef honors veterans while providing an amazing habitat for marine life, perfect for diving and snorkeling enthusiasts.

Best time to go to Panacea

The best time to visit Panacea can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Panacea falls in July and August. August has average visitor numbers and mostly sunny weather. The coolest average temperature in Panacea falls in January, visitor numbers are average and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January53.6°F (12.0°C)Light RainMostly SunnyAverageSlightly Low
February57.6°F (14.2°C)Light RainMostly SunnyAverageAverage
March62.4°F (16.9°C)Light RainMostly SunnyAverageAverage
April68.2°F (20.1°C)Light RainMostly SunnyModerately HighAverage
May74.8°F (23.8°C)Light RainMostly SunnyAverageSlightly High
June80.4°F (26.9°C)Moderate RainMostly SunnyModerately HighAverage
July81.7°F (27.6°C)Moderate RainMostly SunnyModerately HighSlightly Low
August81.7°F (27.6°C)Moderate RainMostly SunnyAverageAverage
September78.4°F (25.8°C)Light RainMostly SunnyAverageSlightly High
October71.1°F (21.7°C)Light RainMostly SunnyModerately LowSlightly High
November61.9°F (16.6°C)Light RainMostly SunnyModerately LowAverage
December57.6°F (14.2°C)Light RainMostly SunnyModerately LowSlightly Low

The nearest major airports for your trip to Panacea

When traveling to Panacea, Florida, you have several airport options. The nearest major airport is Tallahassee International Airport (TLH), located 26 miles away. Nearby hotels include the 4-star DoubleTree by Hilton Hotel Tallahassee and Hotel Duval, Autograph Collection, both 5 miles from the airport, offering shuttle services. Panama City Beach International Airport (ECP) is 87 miles away, with hotels like Sterling Breeze 1904 and Ocean Reef 1601-200291, both 11 miles from the airport. Lastly, Valdosta Regional Airport (VLD) is 85 miles away, featuring Drury Plaza Hotel Valdosta and Hilton Garden Inn Valdosta, both 5 miles from VLD, also providing easy access to the airport.

Why book with Expedia?

  • Flexible booking

    On Expedia, you can find plenty of hotels with flexible cancellation in Panacea using the “Fully refundable property” search filter. Just be sure to always double-check each hotel's cancellation policy before booking.

  • Book now and pay later

    With countless book now, pay later options, there's no need to wait till payday to grab a deal. Use the “Reserve now, pay later” search filter to view all properties available with this payment option in Panacea.

  • Hotel comparison

    Thanks to the handy “Compare properties” tool on Expedia, you can compare hotels in Panacea side by side with just a few clicks.

  • Member prices

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Frequently asked questions

What is the best area to stay in Panacea?
The best area to stay in Panacea is directly along the waterfront, particularly on the western side of the Panacea Bridge, offering easy access to the Gulf of Mexico.

This area is characterized by its direct proximity to the water, with many accommodations featuring docks or private access to the bay. It's a relaxed setting, ideal for those seeking a tranquil retreat. The main road, US-98, runs through this area, providing straightforward access to local seafood restaurants and small shops.

Couples looking for a quiet escape will find this area particularly appealing. The focus here is on enjoying the natural surroundings, with opportunities for kayaking, fishing, or simply watching the sunset over the water. Its secluded nature provides a peaceful backdrop for a romantic getaway.

For travelers who value convenience and a more residential feel, the area just east of the Panacea Bridge offers a good alternative. This section provides a blend of vacation rentals and smaller, locally-owned accommodations, often with more space.
What are the best hotels in Panacea that travelers recommend?
For a highly recommended hotel in Panacea, consider The Panacea Motel.

The Panacea Motel, with a 9.0 rating, is popular by travelers who frequently mention its good value and comfortable beds. Guests also appreciate the nice towels provided. It offers free self-parking and the convenience of early check-in. The motel is also conveniently located near Woolley Park, Gulf Specimen Public Aquarium, and Panacea Park.
What are the top pet-friendly hotels in Panacea?
For pet-friendly hotels in Panacea, The Panacea Motel is an excellent choice.

The Panacea Motel, with a 9.0 rating, warmly welcomes both dogs and cats, making it a convenient option for travelers with pets. Guests often compliment the comfortable beds and the good value for the price. The motel also offers early check-in, which can be very helpful for travel planning. It is conveniently located near Woolley Park and Panacea Park, both within 0.7 miles, superb for walks with your pets, and the Gulf Specimen Public Aquarium is just 0.9 miles away. See more pet-friendly hotels in Panacea
What are the best budget hotels in Panacea?
For a great budget-friendly option in Panacea, The Panacea Motel comes highly recommended.

This motel has a 9.0 rating and offers convenient amenities such as free WiFi and complimentary self-parking. Guests appreciate the good value for the price and the comfortable beds. It is also well-located, with Panacea Springs just 0.2 miles away, Woolley Park 0.6 miles away, and Panacea Park 0.7 miles away. Early check-in is also available.
What are the best hotels in Panacea near Woolley Park?
For a well-located hotel in Panacea near Woolley Park, consider The Panacea Motel.

The Panacea Motel, with a 9.0 rating, is conveniently located just 0.6 miles from Woolley Park. Guests appreciate the comfortable beds and the good value for the price. The motel offers free WiFi and complimentary self-parking, adding to the convenience for travelers.
When is the best time to go to Panacea?
The best time to go to Panacea is during the spring (March to May) and fall (September to November) for pleasant weather and fewer crowds.

Spring offers mild temperatures, typically ranging from the low 60s to high 70s Fahrenheit, making it ideal for outdoor activities like fishing, kayaking, or exploring the local nature trails. The water is comfortable for swimming, and the area's natural beauty is at its peak.

Fall also provides comfortable temperatures, generally from the low 60s to mid-80s Fahrenheit, and the humidity is lower than in the summer. This season is superb for enjoying the local seafood festivals and the quieter atmosphere after the summer rush.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Panacea.
How can I save on a Panacea hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Panacea hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Panacea hotel?
Prices for hotels in Panacea often vary, but you can find a great deal from $104 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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