Car Rental San Luis, CO
Search and Compare from Car Companies in San Luis
Featured car rental suppliers
Compare from agencies
Change your mindPenalty-free cancellation on many/select car rentals
Shop smartCompare car suppliers and package your flight, hotel, and car to save
Top Car Deals in San Luis
* Price found within the past 6 days. Click for updated prices.
Economy
Compact
Midsize
SUV
Frequently asked questions
Car Rental Information
| SUV, Full Size, Economy | |
| Airport Transportation | |
| Airport Car Rentals |
Finding the cheapest car rentals in San Luis
Using our Search Wizard
If the deals that are available on our page do not suit your needs, then enter San Luis into the search wizard at the top of the page. We will compare all the best deals available for your car rental in San Luis and provide you with a list of the cheapest options, with no added fees.
Renting a car in San Luis
Pay at pickup is available, so you don’t have to worry about spending your money until you arrive at your vehicle in San Luis. We partner with reliable partners that guarantee an enjoyable experience for solo travelers, couples, and families. Package your car with a flight or hotel to unlock even more savings from Expedia.
Expected prices in San Luis
Prices are subject to seasonal change depending on when you decide to arrange your car rental but right now you can book .
Flexibility & Cancellation
Most car suppliers offer penalty-free cancellations, so you don’t have to worry about losing money if your plans change. To cancel your booking log into your account through the Trips portal. Click manage booking and cancel this car. If you needed to alter your booking, then you can create a new one once you have canceled.
We all love being rewarded
One Key members save 10% or more on select hotels, cars, activities and vacation rentals. Not only that, earn OneKeyCash for every dollar spent on eligible hotels, vacation rentals, flights, car rentals, and more when you book across our family of brands: Expedia, Hotels.com and VRBO. Learn more and join today.
Car classes available from Expedia in 2025
The classes of vehicles available will change depending on your chosen location.
Explore a world of travel with Expedia
- Vacation Homes in Costilla County
- Hotels near Shrine of the Stations of the Cross
- Chama Hotels
- Hotels near Viejo San Acacio
- Garcia Hotels
- Hotels near Fort Garland Museum
- Fort Garland Hotels
- Cabin Rentals in Fort Garland
- B&B in Fort Garland
- Quiet Resorts & in Fort Garland
- Vacation Homes in Fort Garland
- RV Parks in Fort Garland
- Motels in Fort Garland
- 5 Star Hotels in Fort Garland
- Non-Smoking Hotels in Fort Garland
- Blanca Hotels
- Cabin Rentals in Blanca
- RV Parks in Blanca
- Motels in Blanca
- B&B in Blanca
- Hotels near Cuchara Valley Resort
- Cuchara Hotels
- Cabin Rentals in Cuchara
- RV Parks in Cuchara
- B&B in Cuchara
- Pet-friendly Hotels in Cuchara
- Apartments in Cuchara
- Hotels with Restaurants in Cuchara
- Motels in Cuchara
- Historic Hotels in Cuchara
- Vacation Homes in Cuchara
- Hotels with Laundry Facilities in Cuchara
- Hotels near Blanca Peak Trailhead
- Hotels near Alamosa National Wildlife Refuge
- Sanford Hotels
- B&B in Sanford
- Hotels near Jack Dempsey Museum and Birthplace
- Manassa Hotels
- Flights to Garcia
- Flights to Fort Garland
- Flights from Fort Garland
- Flights from Blanca
- Flights to Blanca
- Flights to Cuchara
- Flights from Cuchara
- Flights to Sanford
- Flights from Denver (DEN) to Alamosa (ALS)
- Flights from San Luis Valley Regional
- Flights from Dallas (DFW) to Alamosa (ALS)
- Flights from Houston (HOU) to Alamosa (ALS)
- Flights from Phoenix (PHX) to Alamosa (ALS)
- Flights from Colorado Springs (COS) to Alamosa (ALS)
- Flights from Salt Lake City (SLC) to Alamosa (ALS)
- Flights from Albuquerque (ABQ) to Alamosa (ALS)
- Flights from St. George (SGU) to Alamosa (ALS)
- Flights from Pueblo (PUB) to Alamosa (ALS)
- Flights from Austin (AUS) to Alamosa (ALS)
- Flights from Durango (DRO) to Alamosa (ALS)
- Flights from Los Angeles (LAX) to Alamosa (ALS)
- Flights from Oklahoma City (OKC) to Alamosa (ALS)
- Flights from Seattle (SEA) to Alamosa (ALS)
- Flights from Grand Junction (GJT) to Alamosa (ALS)
- Flights from Tulsa (TUL) to Alamosa (ALS)
- Flights from Portland (PDX) to Alamosa (ALS)
- Flights from Columbus (CMH) to Alamosa (ALS)
- Flights from Kansas City (MCI) to Alamosa (ALS)
- Flights from Montrose (MTJ) to Alamosa (ALS)
- Flights from Detroit (DTW) to Alamosa (ALS)
- Flights from Indianapolis (IND) to Alamosa (ALS)
- Flights from Chicago (ORD) to Alamosa (ALS)
- Flights from San Antonio (SAT) to Alamosa (ALS)
- Flights from Minneapolis (MSP) to Alamosa (ALS)
- Shrine of the Stations of the Cross
- Viejo San Acacio
- Mother Mary's Garden
- Los Caminos Antiguos
- Visit Fort Garland
- Fort Garland Vacations
- Visit Blanca
- Blanca Vacations
- Cuchara Valley Resort
- Visit Cuchara
- Cuchara Vacations
- Blanca Peak Trailhead
- Alamosa National Wildlife Refuge
- Jack Dempsey Museum and Birthplace
- Car rentals near Chama
- Car rentals near Fort Garland
- Enterprise Rental Cars in Fort Garland
- Budget Rental Cars in Fort Garland
- Car rentals near Blanca
- Car rentals near Monument Park
- Car rentals near Cuchara
- Car rentals near Stonewall
- Car rentals near Manassa
- Car rental Alamosa Airport (ALS)
- Enterprise Rental Cars in San Luis Valley Regional
