Title: Santa Isabel Car Rental - Free Cancellation Options - Expedia.com [Santa Isabel Travel Guide](https://expedia.com/Santa-Isabel.dx6203540)[Hotels in Santa Isabel](https://expedia.com/Santa-Isabel-Hotels.d6203540.Travel-Guide-Hotels)[Flights to Santa Isabel](https://expedia.com/Cheap-Flights-To-Santa-Isabel.d6203540.Travel-Guide-Flights)[Santa Isabel Vacation Packages](https://expedia.com/Santa-Isabel.d6203540.Destination-Travel-Guides) ![](https://images.trvl-media.com/place/6203540/c7b068e1-573b-4f4f-9d2b-445d757c301a.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # $1 Car Rental Santa Isabel ## Search and Compare from Car Companies in Santa Isabel ## Featured car rental suppliers Compare from agencies ![car suppliers logo](https://forever.travel-assets.com/flex/flexmanager/images/2022/02/16/car-suppliers-logo-desktop.jpg) ## Top Car Deals in Santa Isabel \* Price found within the past 6 days. Click for updated prices. Wed, Feb 11 - Thu, Feb 12 ### Special Dealers Choice or similar - 4 people - Unlimited mileage ![Ace](//mediaim.expedia.com/cars/logos/AC.png) Tocumen, PAN ![Dealers Choice](//mediaim.expedia.com/cars/2/1ec0cf0c-80d9-48d6-86a7-929e067c74b1.jpg) #### $1 includes taxes & fees $1 per day found 1 day ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=9.071390&olon=-79.383330&date1=2/11/2026&date2=2/12/2026&pprfrr=1.19&tprfrr=1.4&cvrfrr=AC&ctrfrr=XX&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22other%22]) Wed, Feb 11 - Thu, Feb 12 ### Economy Hyundai Grand i10 HB or similar - 5 people - Unlimited mileage ![Fox](//mediaim.expedia.com/cars/logos/FX.png) Tocumen, PAN ![Hyundai Grand i10 HB](//mediaim.expedia.com/cars/19/5dbdebb4-372e-458a-bc83-72c94e85d03c.jpg) #### $1 includes taxes & fees $1 per day found 1 day ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=9.066900&olon=-79.387400&date1=2/11/2026&date2=2/12/2026&pprfrr=0.71&tprfrr=0.76&cvrfrr=FX&ctrfrr=ED&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22economy%22]) Wed, Feb 11 - Thu, Feb 12 ### Compact Hyundai Accent or similar - 4 people - Unlimited mileage ![NÜ](//mediaim.expedia.com/cars/logos/NU.png) Panama City, PAN ![Hyundai Accent](//mediaim.expedia.com/cars/71/19b8903f-8931-4ec0-9d16-2e95f7442633.jpg) #### $1 includes taxes & fees $1 per day found 1 day ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=9.074380&olon=-79.408230&date1=2/11/2026&date2=2/12/2026&pprfrr=0.9&tprfrr=1.08&cvrfrr=NU&ctrfrr=CC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22compact%22]) Wed, Feb 11 - Thu, Feb 12 ### Midsize Nisan Versa or similar - 5 people - Unlimited mileage ![NÜ](//mediaim.expedia.com/cars/logos/NU.png) Panama City, PAN ![Nisan Versa](//mediaim.expedia.com/cars/71/661cc4c5-f225-4b94-9532-8b51dab9c146.jpg) #### $2 includes taxes & fees $2 per day found 1 day ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=9.074380&olon=-79.408230&date1=2/11/2026&date2=2/12/2026&pprfrr=2.0&tprfrr=2.4&cvrfrr=NU&ctrfrr=IC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22midsize%22]) Tue, Feb 10 - Wed, Feb 11 ### Mini Kia Picanto or similar - 4 people - Unlimited mileage ![Ace](//mediaim.expedia.com/cars/logos/AC.png) Tocumen, PAN ![Kia Picanto](//mediaim.expedia.com/cars/2/96840153-b56b-458a-a2d2-528d3e49a5e7.jpg) #### $4 includes taxes & fees $3 per day found 1 day ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=9.071390&olon=-79.383330&date1=2/10/2026&date2=2/11/2026&pprfrr=3.46&tprfrr=4.07&cvrfrr=AC&ctrfrr=MC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22mini%22]) Wed, Feb 11 - Thu, Feb 12 ### Standard Hyundai Accent or similar - 5 people - Unlimited mileage ![Fox](//mediaim.expedia.com/cars/logos/FX.png) Tocumen, PAN ![Hyundai Accent](//mediaim.expedia.com/cars/19/ae31cb7a-8d9e-4431-882d-c681fa742d6b.jpg) #### $4 includes taxes & fees $4 per day found 1 day ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=9.066900&olon=-79.387400&date1=2/11/2026&date2=2/12/2026&pprfrr=4.11&tprfrr=4.4&cvrfrr=FX&ctrfrr=SD&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22standard%22]) Wed, Feb 11 - Thu, Feb 12 ### Fullsize Hyundai Elantra or similar - 5 people - Unlimited mileage ![Fox](//mediaim.expedia.com/cars/logos/FX.png) Tocumen, PAN ![Hyundai Elantra](//mediaim.expedia.com/cars/19/5c9c25b6-7043-4412-9019-6aae57508c1a.jpg) #### $7 includes taxes & fees $7 per day found 1 day ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=9.066900&olon=-79.387400&date1=2/11/2026&date2=2/12/2026&pprfrr=6.54&tprfrr=7.0&cvrfrr=FX&ctrfrr=FD&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22fullsize%22]) Wed, Feb 11 - Thu, Feb 12 ### Luxury Toyota Corolla or similar - 5 people - Unlimited mileage ![NÜ](//mediaim.expedia.com/cars/logos/NU.png) Panama City, PAN ![Toyota Corolla](//mediaim.expedia.com/cars/71/c5296061-105e-4a5e-9ff6-163a93630984.jpg) #### $18 includes taxes & fees $15 per day found 1 day ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=9.074380&olon=-79.408230&date1=2/11/2026&date2=2/12/2026&pprfrr=15.0&tprfrr=17.98&cvrfrr=NU&ctrfrr=LC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22luxury%22]) Wed, Feb 11 - Thu, Feb 12 ### Premium Toyota Corolla or similar - 5 people - Unlimited mileage ![Alamo](//mediaim.expedia.com/cars/logos/AL.png) Panama City, PAN ![Toyota Corolla](//mediaim.expedia.com/cars/6/bc1b08c4-e7d4-4467-9c08-d2bc3187ae21.jpg) #### $22 includes taxes & fees $19 per day found 1 day ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=9.067050&olon=-79.386900&date1=2/11/2026&date2=2/12/2026&pprfrr=18.59&tprfrr=22.28&cvrfrr=AL&ctrfrr=PC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22premium%22]) ### Don't see what you're looking for? See all car rentals in Santa Isabel [View all cars](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santa%20Isabel,%20Col%C3%B3n,%20Panama&dpln=6203540&date1=2/14/2026&date2=2/16/2026&crfrr=defaultFlex&SearchType=Place) ## Frequently asked questions ### How much is a rental car per day in Santa Isabel? ### What happens if I need to cancel my Santa Isabel car reservation? ### Where can I go on a road trip from Santa Isabel? > - You'll find Bridge of the Americas and loads more intriguing attractions in Arraijan. From Santa Isabel, it's 50 miles away. > - Why not check out the best of Colon too? Notable tourist attractions in this buzzing city include Gatun Locks. Colon is approximately 50 miles from Santa Isabel. > - Venao Beach is 160 miles from Santa Isabel and is one of the region's most breathtaking nature spots. Stretch your legs and enjoy the fresh air. ### How do I find the best car rental deals in Santa Isabel with Expedia? ### What do you need to rent a car in Santa Isabel? ### What is the cheapest car rental in Santa Isabel? ### Can I rent a car for a month or longer in Santa Isabel? ### Where can I find a Santa Isabel car rental if I am younger than 25? ### What insurance should I choose for my car rental in Santa Isabel? ### Can I drive in Santa Isabel with my current driver's license? > - Age restrictions: You need to be at least 25 in many countries to rent a car. If you're younger than that, it may still be possible to rent a car but you'll have to pay a Young Driver's Surcharge. Additional restrictions may also apply to the types of cars you can rent. > - Driving limitations: Be sure to read the rules and regulations before you drive away. You typically can't cross country borders, drive on ferries or go off-roading with your rental car. ## Car Rental Information | Popular car types | [SUV](https://www.expedia.com/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.com/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.com/lp/b/car-rental/economy?rfrr=car.table.Economy) | | ------------------------------------------------ | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available | | | Our best deal of the day | $1 | | Our second best deal of the day | $2 | | Our third best deal of the day | $4 | | From the airport to your hotel | [Airport Transportation](https://www.expedia.com/ground-transfers?rfrr=car.table.AirportTransportation) | | From popular domestic and international airports | [Airport Car Rentals](https://www.expedia.com/lp/b/car-rental/airport) | ## Finding the cheapest car rentals in Santa Isabel ### **Using our Search Wizard** If the deals that are available on our page do not suit your needs, then enter Santa Isabel into the search wizard at the top of the page. We will compare all the best deals available for your car rental in Santa Isabel and provide you with a list of the cheapest options, with no added fees. ### **Renting a car in Santa Isabel** Pay at pickup is available, so you don’t have to worry about spending your money until you arrive at your vehicle in Santa Isabel. We partner with reliable partners that guarantee an enjoyable experience for solo travelers, couples, and families. Package your car with a flight or hotel to unlock even more savings from Expedia. ### **Expected prices in Santa Isabel** Prices are subject to seasonal change depending on when you decide to arrange your car rental but right now you can book from $1. ### **Flexibility & Cancellation** Most car suppliers offer penalty-free cancellations, so you don’t have to worry about losing money if your plans change. To cancel your booking log into your account through the [Trips](https://www.expedia.com/trips) portal. Click manage booking and cancel this car. If you needed to alter your booking, then you can create a new one once you have canceled. ### **We all love being rewarded** [One Key](https://www.expedia.com/welcome-one-key?langid=1033) members save 10% or more on select hotels, cars, activities and vacation rentals. Not only that, earn OneKeyCash for every dollar spent on eligible hotels, vacation rentals, flights, car rentals, and more when you book across our family of brands: Expedia, Hotels.com and VRBO. Learn more and join today. ### **Car classes available from Expedia in 2026** The classes of vehicles available will change depending on your chosen location. - [Compact car rentals](https://www.expedia.com/lp/b/car-rental/compact) - [Convertible car rentals](https://www.expedia.com/lp/b/car-rental/convertible) - [Economy car rentals](https://www.expedia.com/lp/b/car-rental/economy) - [Fullsize car rentals](https://www.expedia.com/lp/b/car-rental/fullsize) - [Luxury car rentals](https://www.expedia.com/lp/b/car-rental/luxury) - [Midsize car rentals](https://www.expedia.com/lp/b/car-rental/midsize) - [Mini car rentals](https://www.expedia.com/lp/b/car-rental/mini) - [Minivan rentals](https://www.expedia.com/lp/b/car-rental/minivan) - [Pickup car rentals](https://www.expedia.com/lp/b/car-rental/pickup) - [Premium car rentals](https://www.expedia.com/lp/b/car-rental/premium) - [Sportscar rentals](https://www.expedia.com/lp/b/car-rental/sportscar) - [Standard car rentals](https://www.expedia.com/lp/b/car-rental/standard) - [SUV rentals](https://www.expedia.com/lp/b/car-rental/suv) - [Van rentals](https://www.expedia.com/lp/b/car-rental/van)