
Santa Isabel Vacations from $812
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The Latest Santa Isabel vacation packages
Price found within the past 48 hours. Click for updated prices.

Hotel Riu Plaza Panama
Bella Vista
per person
Oct 11 - Oct 18
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9/10 Wonderful! (4,141 reviews)
We were disappointed by the fact that the pool was being renovated (therefore closed) and we were not notified until we were checking in at the hotel.
Reviewed on Aug 18, 2025

La Coralina Island House
Save 100% on your flight
per person
Nov 7 - Nov 12
found 3 hours ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
9.4/10 Exceptional! (83 reviews)
Wow! This resort is absolutely amazing! Bekar went above and beyond for us! He even brought in a TV to the lobby so we could watch the NHL playoff game! Food is 10/10 as well. We will definitely go back!
Reviewed on May 18, 2025

Central Hotel Panama Casco Viejo
Casco Viejo
Save 100% on your flight
per person
Sep 24 - Oct 1
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9/10 Wonderful! (965 reviews)
Perfectly located for seeing Casco Viejo, and beautifully maintained as an historic building. Staff was absolutely accommodating and responsive to all requests (and we had a few!).
Reviewed on Aug 18, 2025


Villa Marina Lodge & Condos
per person
Nov 7 - Nov 12
found 3 hours ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
9/10 Wonderful! (127 reviews)
Love that this property is at the other end of the beach from the late night partying. Walkable beach. Great restaurants nearby. The property was adding coffee makers and mini fridges the day we were leaving. Great staff, restaurant and drinks. We’ve been twice with our pooches. Will be back
Reviewed on Jul 14, 2025
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Private Ocean-Front Cabin with private bathroom on San Blas Island
Diablo Island, Narganá, Guna Yala

Private Over the Water Cabin on San Blas Island
9.542876, -78.899058, Narganá, San Blas
7/10 Good! (6 reviews)
"Very nice. And I liked the food"
Reviewed on Aug 14, 2025

San Blas Paradise Private Cabins on Shipwreck Island - meals included
Perro Island, Narganá, Guna Yala
$169 nightly
The price is $186 total per night from Aug 19 to Aug 20
$186 total
Aug 19 - Aug 20
Total includes taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.