
Santa Isabel Vacations from $687
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The Latest Santa Isabel vacation packages
Price found within the past 48 hours. Click for updated prices.

Mahogany Suites
Price was $1,091, price is now $687 per person
$687
per person
Jun 10 - Jun 14
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.4/10 Exceptional! (8 reviews)
This is a very nice gated country club. It has great amenities and the apartment is in excellent condition and very comfortable. We only had one issue and that was with the dryer not working, which we didn’t discover until we had already washed a load of clothes. There isn’t a lobby that is staffed at this location, and it’s not clear who to contact with issues. The “check-in” occurred at the security gate as you arrive to the country club. But despite the lack of clear instructions you get when booking, I still recommend this place, especially if you have more than a one night stay, and would stay here again.
Reviewed on Mar 16, 2026

Central Hotel Panama Casco Viejo
Casco Viejo
Save 100% on your flight
Price was $2,228, price is now $1,479 per person
$1,479
per person
Jun 13 - Jun 20
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (1,000 reviews)
Fabulous hotel is just the right location. Breakfast buffet is unmatched. Staff was very helpful no matter how big or small our request. Great amenities with spa, roof deck.
Reviewed on Apr 7, 2026

Hotel Plaza Herrera
Casco Viejo
Price was $1,408, price is now $967 per person
$967
per person
May 29 - Jun 1
found 15 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.8/10 Exceptional! (34 reviews)
Internet was good. Suite was spacious. Shower and clothing closet on a seperate floor from bedroom. Ceiling fan was quiet and finctioning. A/C also quiet and functioning. Deck fan operates on a chain that was to short. Hammock on the deck takes alot of space where some decent seating and a small table might be. Great view of the park and street activity. Location is not know to Uber. Early morning coffee is available. Paid for morning breakfast with room online ... used 1 of 2 breakfasts, no credit offered. Breakfast quality is reasonable and tasted good. Staff are probably best asset at this property. They try very hard to make guests welcome amd comfortable. I did not feel like was being worked for an expected tip at all.
Reviewed on Mar 24, 2026

Radisson Riviera Panama
Price was $1,091, price is now $789 per person
$789
per person
May 21 - May 28
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
8.6/10 Excellent! (129 reviews)
Great and lovely place!!! The staff was so helpful even when I had some water temperature issues it was a great stay, if you’re looking for activities as a solo traveler maybe try another resort since most of the excursions you need more than 1 person.
Reviewed on Apr 1, 2026

Surfside Beachfront Suites by Playa Caracol Resorts
Price was $964, price is now $700 per person
$700
per person
May 13 - May 18
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
7.6/10 Good! (37 reviews)
Love this trip your own private paradise we are definitely going again
Reviewed on Mar 27, 2026
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Private Ocean-Front Cabin with private bathroom on San Blas Island
Diablo Island Narganá Guna Yala
10/10 Exceptional! (1 review)
Staff was wonderful. Room was basic, as described. Basically camping on the beach with a comfortable bed. Fall asleep to ocean waves just feet from the door.
Reviewed on Mar 15, 2026

Cocoloco - Catamaran Lagoon 52F SAN BLAS
El Porvenir Narganá Guna Yala
Fully refundableReserve now, pay when you stay
$1,953 nightly
The price is $2,158 total per night from Apr 16 to Apr 17
$2,158 total
Apr 16 - Apr 17
Total with taxes and fees

Paradise Over the Water Cabins in San Blas
G4V2 48 Narganá Guna Yala
6/10 (1 review)
29/22 i stay with my family for three nights and 4 days the beds are not comfortable and the fan doesn't work the bathroom need cleaning, the worst part is the sandflyies we got bitten all over our bodies, the owners can do better with proper new nets and fan and maybe spray the place, after the ...
Reviewed on Sep 4, 2022
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Santa Isabel Vacation Packages
Santa Isabel Essential Information
Language | Spanish |
|---|---|
Currency | Panamanian balboas |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Population | 260 |
Max Temp Winter | 80ºF |
Max Temp Summer | 80ºF |
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