
Santa Isabel Vacations from $944
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The Latest Santa Isabel vacation packages
Price found within the past 48 hours. Click for updated prices.

Hotel Riu Plaza Panama
Bella Vista
Price was $1,400, price is now $944 per person
$944
per person
Aug 2 - Aug 8
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (5,488 reviews)
I really had a good time at RIU the services was really nice and the breakfast
Reviewed on May 30, 2026

Central Hotel Panama Casco Viejo
Casco Viejo
Save 100% on your flight
Price was $2,002, price is now $1,091 per person
$1,091
per person
Aug 2 - Aug 8
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.2/10 Wonderful! (1,003 reviews)
The location is great !,
Great food and service !
Reviewed on May 29, 2026

Megapolis Hotel Panamá
San Francisco
Price was $1,687, price is now $1,132 per person
$1,132
per person
Aug 2 - Aug 8
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
8.4/10 Very Good! (1,538 reviews)
La habitación tenia una hermosa vista, muy limpia, desde nuestra llegada su personal fue correcta, amable y muy servicial, los desayunos fueron exquisitos a otro nivel y había de todo muy cerca de todo.
Reviewed on May 26, 2026

Boutique Apartments Panamá Coco del Mar
San Francisco
Save 100% on your flight
Price was $3,955, price is now $2,761 per person
$2,761
per person
Jul 21 - Jul 27
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
7.6/10 Good! (195 reviews)
Overall, we had a decent stay and would rate this apartment 4/5. The location and general setup were good, and we appreciated the space and comfort during our trip. However, there were a few issues that affected the experience.
The main concern was the water temperature in the shower, as the hot and cold water did not mix properly, making it difficult to get a comfortable temperature consistently.
The internet was also a major issue for the first two days of our stay. We had little to no reliable connection until our third night, which was inconvenient, especially for communication and planning activities.
Additionally, one of the bathrooms had a persistent unpleasant smell throughout the stay. Even after using disinfectant spray multiple times, the odor remained until checkout.
Despite these concerns, the apartment still had positive aspects, which is why we are giving it a 4 out of 5. We hope these issues can be addressed to improve future guests’ experiences.
Ooh the refrigerator form ice on out pizza.
Reviewed on May 20, 2026

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Private Ocean-Front Cabin with private bathroom on San Blas Island
Diablo Island Narganá Guna Yala
10/10 Exceptional! (1 review)
"Staff was wonderful. Room was basic, as described. Basically camping on the beach with a comfortable bed. Fall asleep to ocean waves just feet from the door."
Reviewed on Mar 15, 2026

Caribbean Haven Of Nature 'Preci Beach'
Nombre de Dios Colon
10/10 Exceptional! (31 reviews)
Beautiful
"This place is special. The inside of the house could use a deep cleaning. But the outdoor area and beach area are incredible. We explored tide pools and snorkeled open areas and crevices all week long. Our one negative experience was fishing with some young men from the nearby town; they did not ..."
Reviewed on Mar 17, 2025

Cocoloco - Catamaran Lagoon 52F SAN BLAS
El Porvenir Narganá Guna Yala
Fully refundableReserve now, pay when you stay
$1,984 nightly
The price is $2,189 total per night from Jun 1 to Jun 2
$2,189 total
Jun 1 - Jun 2
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Santa Isabel Vacation Packages
Santa Isabel Essential Information
Language | Spanish |
|---|---|
Currency | Panamanian balboas |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Population | 260 |
Max Temp Winter | 80ºF |
Max Temp Summer | 80ºF |
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