Santa Isabel Vacations from $898
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The Latest Santa Isabel vacation packages
Price found within the past 48 hours. Click for updated prices.
Riande Aeropuerto Hotel & Casino
Tocumen Airport
$898
per person
Dec 24 - Dec 31
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
8.6/10 Excellent! (1,819 reviews)
This is a lovely hotel with peaceful surroundings and very helpful staff. The breakfast was very extensive with a lot of variety.
Reviewed on Oct 12, 2026
Megapolis Hotel Panamá
San Francisco
$1,309
per person
Dec 24 - Dec 31
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
8.6/10 Excellent! (1,764 reviews)
Realmente me gustó todo el hotel desde que llegamos hasta que nos fuimos la atención fue 10/10 quedé muy satisfecha con la atención me encantó muy bello
Reviewed on Oct 12, 2026
Hotel Riu Plaza Panama
Bella Vista
$987
per person
Dec 24 - Dec 31
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9/10 Wonderful! (5,990 reviews)
Stayed here twice and enjoyed it both times! The staff are very friendly rooms are clean and that breakfast buffet amazing!!!
Reviewed on Oct 12, 2026
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Private Ocean-Front Cabin with private bathroom on San Blas Island
Diablo Island Narganá Guna Yala
$188 nightly
$207 total
Oct 14 - Oct 15
Total with taxes and fees
10/10 Exceptional! (1 review)
"Staff was wonderful. Room was basic, as described. Basically camping on the beach with a comfortable bed. Fall asleep to ocean waves just feet from the door."
Reviewed on Mar 15, 2026
Cocoloco - Catamaran Lagoon 52F SAN BLAS
El Porvenir Narganá Guna Yala
$1,677 nightly
$1,882 total
Nov 12 - Nov 13
Total with taxes and fees
Caribbean Haven Of Nature 'Preci Beach'
Nombre de Dios Colon
10/10 Exceptional! (32 reviews)
"This is a great place to slow down and enjoy the sea and on-site amenities, including a pool, hot tub, sand volleyball court, and kid-friendly play spaces. This is very much a home that the owners make available to guests. Cone, the on-site custodian, is available and helpful. It is somewhat remote ..."
Reviewed on Oct 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Santa Isabel Vacation Packages
Santa Isabel Essential Information
Language | Spanish |
|---|---|
Currency | Panamanian balboas |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Population | 260 |
Max Temp Winter | 80ºF |
Max Temp Summer | 80ºF |
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Frequently asked questions
How much does a Santa Isabel vacation package cost?
You'll find cheap prices from $898 on Expedia for your Santa Isabel getaway. However, factors like the season, choice of hotel and length of stay will determine how much your vacation to Santa Isabel costs.
What are the cheapest months to go to Santa Isabel?
You can typically find lower prices and better availability in August, November and December. Take a look at our cheap Santa Isabel vacation packages and you could land some excellent off-season deals.
How many days is enough for Santa Isabel?
Typically, a handful of days is enough to visit the major attractions during your Santa Isabel vacation. However, if you want to have some time to kick back or go on day trips, consider extending your itinerary.
How to find the best Santa Isabel package deals?
Finding a cheap Santa Isabel package deal is a breeze with Expedia. Once you've entered your destination and travel dates under our "Packages" tab, set your maximum budget, add a few filters and see what's available. You can personalize your search by "Area," "Amenities," "Property type" and more. Sort the results by "Price: low to high" to discover the most wallet-friendly Santa Isabel package deals. Want a simple trick to score the biggest savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are often lower.
Is it cheaper to book a Santa Isabel vacation as a package?
You can enjoy significant savings on your Santa Isabel break by booking a personalized vacation package. Click on the "Package" heading, then select your travel dates and destination to browse some great airfares and hotel prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a rental car and you may score a better deal.
When to book a vacation package to Santa Isabel?
Enjoy incredible bargains by reserving your flights early with Expedia. If spontaneity is more your style, take advantage of our last-minute deals for a spur-of-the-moment Santa Isabel getaway.
Does Expedia offer Book Now, Pay Later Santa Isabel vacation packages?
Set off on your dream escape to Santa Isabel with help from our Book Now, Pay Later vacations. There's no need to save up or hold off until your next paycheck — we've partnered with online lender Affirm to give you flexibility with your finances. Our vacation packages with payment plans mean you can split the cost across 3, 6 or 12 months. With no late payment fees or hidden charges, it's easy to stay on budget and snap up travel deals before they disappear.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
