Title: $75 Car Rental UC Irvine Medical Center, CA - Expedia.com [Orange Travel Guide](https://expedia.com/Orange.dx9063)[UC Irvine Medical Center Hotels](https://expedia.com/UC-Irvine-Medical-Center-Hotels.0-l6282680-0.Travel-Guide-Filter-Hotels)[Flights to Orange](https://expedia.com/Cheap-Flights-To-Orange.d9063.Travel-Guide-Flights)[Things to do in Orange](https://expedia.com/Things-To-Do-In-Orange.d9063.Travel-Guide-Activities)[UC Irvine Medical Center Vacations](https://expedia.com/UC-Irvine-Medical-Center-Orange.d6282680.Vacation-Attraction) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_car.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # $75 Car Rental UC Irvine Medical Center, CA ## Search and Compare from Car Companies in UC Irvine Medical Center ## Featured car rental suppliers Compare from agencies ![car suppliers logo](https://forever.travel-assets.com/flex/flexmanager/images/2022/02/16/car-suppliers-logo-desktop.jpg) ## Top Car Deals in UC Irvine Medical Center \* Price found within the past 6 days. Click for updated prices. Mon, Feb 16 - Tue, Feb 17 ### Special Supplier Choice - Compact or larger or similar - 5 people - Unlimited mileage ![U-Save](//mediaim.expedia.com/cars/logos/SV.png) Irvine, California, USA ![Supplier Choice - Compact or larger](//mediaim.expedia.com/cars/34/2bc25045-b7e7-4bbc-83b9-f880546f8ecc.jpg) #### $86 includes taxes & fees $33 per day found 21 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=33.668070&olon=-117.865610&date1=2/16/2026&date2=2/17/2026&pprfrr=33.22&tprfrr=86.38&cvrfrr=SV&ctrfrr=XX&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22other%22]) Mon, Feb 16 - Tue, Feb 17 ### Economy Hyundai Accent or similar - 5 people - Unlimited mileage ![U-Save](//mediaim.expedia.com/cars/logos/SV.png) Irvine, California, USA ![Hyundai Accent](//mediaim.expedia.com/cars/34/cf1b954e-ce0f-4c41-ad5f-a928110df0a3.jpg) #### $86 includes taxes & fees $33 per day found 21 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=33.668070&olon=-117.865610&date1=2/16/2026&date2=2/17/2026&pprfrr=33.22&tprfrr=86.38&cvrfrr=SV&ctrfrr=EC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22economy%22]) Sat, Feb 14 - Sun, Feb 15 ### Midsize SUV Nissan Rogue or similar - 5 people - Unlimited mileage ![Thrifty](//mediaim.expedia.com/cars/logos/ZT.png) Santa Ana, California, USA ![Nissan Rogue](//mediaim.expedia.com/cars/45/1be06a2c-db8d-49a8-8f4f-cb4db24d9990.jpg) #### $75 includes taxes & fees $49 per day found 6 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=33.680919&olon=-117.859144&date1=2/14/2026&date2=2/15/2026&pprfrr=49.42&tprfrr=75.02&cvrfrr=ZT&ctrfrr=IF&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22suv%22]) Sat, Feb 14 - Sun, Feb 15 ### Standard SUV Chevrolet Equinox or similar - 5 people - Unlimited mileage ![Thrifty](//mediaim.expedia.com/cars/logos/ZT.png) Santa Ana, California, USA ![Chevrolet Equinox](//mediaim.expedia.com/cars/45/74679cb4-c978-4a24-8de4-09fbd1976784.jpg) #### $78 includes taxes & fees $50 per day found 6 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=33.680919&olon=-117.859144&date1=2/14/2026&date2=2/15/2026&pprfrr=50.42&tprfrr=77.67&cvrfrr=ZT&ctrfrr=SF&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22suv%22]) Sat, Feb 14 - Sun, Feb 15 ### Fullsize Recreational Vehicle Nissan Pathfinder or similar - 7 people - Unlimited mileage ![Thrifty](//mediaim.expedia.com/cars/logos/ZT.png) Santa Ana, California, USA ![Nissan Pathfinder](//mediaim.expedia.com/cars/45/1d171941-6a49-4be1-8846-c407f80ff153.jpg) #### $85 includes taxes & fees $55 per day found 6 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=33.680919&olon=-117.859144&date1=2/14/2026&date2=2/15/2026&pprfrr=55.46&tprfrr=85.33&cvrfrr=ZT&ctrfrr=FR&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22fullsize%22]) Sat, Feb 14 - Sun, Feb 15 ### Premium Pickup Regular Cab Ford F150 or similar - 5 people - Unlimited mileage ![Alamo](//mediaim.expedia.com/cars/logos/AL.png) Santa Ana, California, USA ![Ford F150](//mediaim.expedia.com/cars/6/540fb0f7-9b8f-4fbc-93be-7057b591d5a3.jpg) #### $114 includes taxes & fees $65 per day found 6 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=33.668087&olon=-117.866543&date1=2/14/2026&date2=2/15/2026&pprfrr=65.00&tprfrr=114.18&cvrfrr=AL&ctrfrr=PP&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22pickup%22]) Mon, Feb 16 - Tue, Feb 17 ### Mini Van Dodge Caravan or similar - 7 people - Unlimited mileage ![U-Save](//mediaim.expedia.com/cars/logos/SV.png) Irvine, California, USA ![Dodge Caravan](//mediaim.expedia.com/cars/34/f380c9bc-4f23-4bde-b75b-d3edce931852.jpg) #### $175 includes taxes & fees $68 per day found 21 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=33.668070&olon=-117.865610&date1=2/16/2026&date2=2/17/2026&pprfrr=68.17&tprfrr=174.95&cvrfrr=SV&ctrfrr=MV&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22minivan%22]) Sun, Feb 15 - Mon, Feb 16 ### Compact Nissan Versa Note or similar - 5 people - Unlimited mileage ![Dollar](//mediaim.expedia.com/cars/logos/ZR.png) Santa Ana, California, USA ![Nissan Versa Note](//mediaim.expedia.com/cars/43/79fd35f4-a9f4-405e-a7d7-3a501dfc88c1.jpg) #### $87 includes taxes & fees $70 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=33.666660&olon=-117.866700&date1=2/15/2026&date2=2/16/2026&pprfrr=69.75&tprfrr=87.26&cvrfrr=ZR&ctrfrr=CC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22compact%22]) Sun, Feb 15 - Mon, Feb 16 ### Luxury Audi A4 or BMW 3 Series or similar - 5 people - Unlimited mileage ![Alamo](//mediaim.expedia.com/cars/logos/AL.png) Santa Ana, California, USA ![Audi A4 or BMW 3 Series](//mediaim.expedia.com/cars/6/f84d223e-53e9-443e-bfd1-5b43e349e9be.jpg) #### $135 includes taxes & fees $108 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=33.668087&olon=-117.866543&date1=2/15/2026&date2=2/16/2026&pprfrr=108.01&tprfrr=135.28&cvrfrr=AL&ctrfrr=LC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22luxury%22]) ### Don't see what you're looking for? See all car rentals in UC Irvine Medical Center [View all cars](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=UC%20Irvine%20Medical%20Center,%20Orange,%20California,%20United%20States%20of%20America&dpln=6282680&date1=2/17/2026&date2=2/19/2026&crfrr=defaultFlex&SearchType=Place) Lowest prices found within the past 21 hours. Prices and availability subject to change. Additional terms may apply. ## Frequently asked questions ### Can I rent a car near UC Irvine Medical Center? ### How much is car rental near UC Irvine Medical Center? ### Which car rental companies have a drop off near UC Irvine Medical Center? ### How much is parking near UC Irvine Medical Center? ### Are there electric car charging stations near UC Irvine Medical Center? ### What is the closest airport to UC Irvine Medical Center? ### Where is UC Irvine Medical Center in Orange? ### What else is there to do near UC Irvine Medical Center? ### What time does UC Irvine Medical Center open and close? ## Car Rental Information | Popular car types | [SUV](https://www.expedia.com/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.com/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.com/lp/b/car-rental/economy?rfrr=car.table.Economy) | | ------------------------------------------------ | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available | | | Our best deal of the day | $75 | | Our second best deal of the day | $78 | | Our third best deal of the day | $85 | | From the airport to your hotel | [Airport Transportation](https://www.expedia.com/ground-transfers?rfrr=car.table.AirportTransportation) | | From popular domestic and international airports | [Airport Car Rentals](https://www.expedia.com/lp/b/car-rental/airport) | ## Explore a world of travel with Expedia - 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