Visit Chaffee
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
$90 nightly
The price is $102 total per night from Dec 7 to Dec 8
$102 total
Dec 7 - Dec 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,004 reviews)
We had a wonderful stay at this hotel. The room and common areas were spotless and the food was wonderful. Our children had a glorious time swimming in the indoor pool.
Reviewed on Nov 26, 2025
The Riverview
777 Main St Cape Girardeau MO
$106 nightly
The price is $120 total per night from Nov 30 to Dec 1
$120 total
Nov 30 - Dec 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau ...
9.4/10 Exceptional! (460 reviews)
Nice property
Reviewed on Nov 24, 2025
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
$70 nightly
The price is $79 total per night from Dec 3 to Dec 4
$79 total
Dec 3 - Dec 4
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,005 reviews)
Clean room. Clean well stocked bathroom. Nice big bathroom. Very courteous check in attendent. And sweet lady serving breakfast.
Reviewed on Nov 26, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
The Twisted Sassafras Treehouse
Cape Girardeau MO
Stay at this cabin in Cape Girardeau. Enjoy a garden, patios, and an in-room coffeemaker. Popular attractions Cape Girardeau Conservation Nature Center and Cape ...
10/10 Exceptional! (26 reviews)
This is the perfect private romantic getaway! We had such a blast here. Definitely recommend!
Reviewed on Nov 2, 2025
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
Cape Girardeau MO
Stay at this apartment in Cape Girardeau. Enjoy free WiFi, a garden, and in-room jetted tubs. Popular attractions eDen Spa & Salon and Riverfront Park are located ...
9.4/10 Exceptional! (43 reviews)
Loved the vibe of the place. Beds were super comfy!
Reviewed on Nov 10, 2025
“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau
Cape Girardeau MO
Book a stay at this family-friendly vacation home in Cape Girardeau. Enjoy free WiFi, a water park, and a garden. Popular attractions Isle Casino Cape Girardeau ...
10/10 Exceptional! (26 reviews)
This home is picture perfect!! Chip (and Busy) were wonderful hosts and gave a grand tour of the home along with pointing out architectural and period details in this historic Dutch Colonial Revival. The property is set up away from the street in a very quiet neighborhood. Everything we could have ...
Reviewed on Nov 14, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
- Mississippi River
- Shawnee National Forest
- Southeast Missouri State University
- Isle Casino Cape Girardeau
- Riverfront Park
- Hunter Valley Winery
- Trail of Tears State Park
- Riverfront Bridge Park
- Cape Splash Family Aquatic Center
- eDen Spa & Salon
- Central Park
- Cape Rock Park
- Sikeston Depot Museum
- Litz Park
- Cape Girardeau Conservation Nature Center
- Lazy L Safari Park
- Fort D Historic Site