Title: Visit Chaffee: 2026 Travel Guide for Chaffee, Missouri | Expedia.com [Hotels in Chaffee](https://expedia.com/Chaffee-Hotels.d553248634983269107.Travel-Guide-Hotels)[Vacation Rentals in Chaffee](https://expedia.com/Chaffee-Vacation-Rentals.d553248634983269107.Travel-Guide-VacationRentals)[Car Rentals in Chaffee](https://expedia.com/Car-Rentals-In-Chaffee.d553248634983269107.Car-Rental-Guide)[Chaffee Vacation Packages](https://expedia.com/Chaffee.d553248634983269107.Destination-Travel-Guides) # Chaffee, MO ## Travel Guide ![Chaffee](https://images.trvl-media.com/place/553248634983269107/3aabcda1-7e0a-4df4-9788-5f9645899bfb.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Chaffee](https://images.trvl-media.com/place/553248634983269107/13e31245-382d-465b-a415-fb3e2cf47f66.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Chaffee - Chaffee Hotel Deals - Vacation Rentals in Chaffee ![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/5929e46c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Plaza Hotel Cape Girardeau Conference Center 3351 Percy Drive Cape Girardeau MO $100 nightly $113 total Apr 5 - Apr 6 Total with taxes and fees Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ... 9.6/10 Exceptional! (1,004 reviews) We very much enjoyed our stay. The evening drinks and food were great, as were the breakfast options. It was our first time staying here, but not the last. Reviewed on Mar 30, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=17269948&PinnedHotelID=17269948&HadPinnedHotel=true®ionId=553248634983269107) ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Riverview 777 Main St Cape Girardeau MO $119 nightly $134 total Apr 6 - Apr 7 Total with taxes and fees Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau ... 9.4/10 Exceptional! (537 reviews) This was a nice hotel, very reasonably priced, nice view, clean, and comfortable. Reviewed on Mar 31, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F6%2F2026&endDate=4%2F7%2F2026&selected=105081384&PinnedHotelID=105081384&HadPinnedHotel=true®ionId=553248634983269107) ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/85184a8e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Inn & Suites Sikeston, MO 2608 East Malone Ave, Miner Sikeston MO $94 nightly $108 total Apr 5 - Apr 6 Total with taxes and fees Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ... 9.6/10 Exceptional! (1,007 reviews) Our first visit to a Drury Inn — what an amazing place. Not only was there an excellent breakfast with many choices, but there was also a light dinner served. This was all included for a very reasonable price. Our room was very clean and comfortable. We will definitely be looking for more Drury Inns ... Reviewed on Mar 30, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=24210&PinnedHotelID=24210&HadPinnedHotel=true®ionId=553248634983269107) [See all 104 properties in Chaffee](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=4%2F1%2F2026&endDate=4%2F2%2F2026®ionId=553248634983269107) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Little Blue Cottage on Spanish](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/143b0eab_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Little Blue Cottage on Spanish Cape Girardeau MO Stay at this vacation home in Cape Girardeau. Popular attractions eDen Spa & Salon and The Glenn House are located nearby. [](https://expedia.com/Cape-Girardeau-Hotels-Little-Blue-Cottage-On-Spanish.h45712431.Hotel-Information) ![“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau](https://images.trvl-media.com/lodging/77000000/76550000/76544100/76544096/1e923d10_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### “Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau Cape Girardeau MO Stay at this vacation home in Cape Girardeau. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Isle Casino Cape Girardeau and Riverfront ... 10/10 Exceptional! (35 reviews) House is an old relic and awesome. Very clean and very nice. Chip was super friendly and will stay again when I’m the area. Reviewed on Mar 24, 2026 [](https://expedia.com/Cape-Girardeau-Hotels-Remodeled-1920s-Dutch-Colonial-Revival-In-Downtown-Cape-Girardeau.h76544096.Hotel-Information) ![Peaceful secluded cabin located near Horseshoe Lake ](https://images.trvl-media.com/lodging/110000000/109740000/109730100/109730068/1be40475_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Peaceful secluded cabin located near Horseshoe Lake Miller City IL Stay at this cabin in Alexander County. Enjoy an in-room coffeemaker and air conditioning. 9.8/10 Exceptional! (24 reviews) This was an amazing property. We our stay here with our doodles while hiking and exploring Shawnee Forest. Private, comfortable and unique! Reviewed on Mar 30, 2026 [](https://expedia.com/Peaceful-Secluded-Cabin-Located-Near-Horseshoe-Lake.h109730068.Hotel-Information) [See all properties in Chaffee](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=553248634983269107&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Chaffee hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983269107&startDate=2026-03-31&endDate=2026-04-01)[Mar 31 - Apr 1](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983269107&startDate=2026-03-31&endDate=2026-04-01) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983269107&startDate=2026-04-01&endDate=2026-03-02)[Apr 1 - Apr 2](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983269107&startDate=2026-04-01&endDate=2026-03-02) [This weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983269107&startDate=4%2F3%2F2026&endDate=4%2F5%2F2026)[Apr 3 - Apr 5](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983269107&startDate=4%2F3%2F2026&endDate=4%2F5%2F2026) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983269107&startDate=4%2F10%2F2026&endDate=4%2F12%2F2026)[Apr 10 - Apr 12](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983269107&startDate=4%2F10%2F2026&endDate=4%2F12%2F2026) ## Cities near Chaffee ![Aerial Photo of Cape Girardeau, Missouri, USA](https://images.trvl-media.com/place/820/34f5c59a-7e57-4244-94c6-c657830fc4ab.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Cape Girardeau - Cities near Chaffee - Places of interest [Cape Girardeau](https://expedia.com/Cape-Girardeau.dx820)[Oran](https://expedia.com/Oran.dx3000445386) - [Shawnee National Forest ](https://expedia.com/Shawnee-National-Forest-Illinois.d553248635944113522.Vacation-Attraction) - [Mississippi River ](https://expedia.com/Mississippi-River-United-States-of-America.d6209928.Vacation-Attraction) - [Century Casino & Hotel Cape Girardeau ](https://expedia.com/Century-Casino-Hotel-Cape-Girardeau-Cape-Girardeau.d553248621532655780.Vacation-Attraction) - [Southeast Missouri State University ](https://expedia.com/Southeast-Missouri-State-University-Cape-Girardeau.d553248621554122994.Vacation-Attraction) - [Riverfront Bridge Park ](https://expedia.com/Riverfront-Bridge-Park-Cape-Girardeau.d553248621532655774.Vacation-Attraction) - [Hunter Valley Winery ](https://expedia.com/Hunter-Valley-Winery-Cape-Girardeau.d553248621532655783.Vacation-Attraction) - [Riverfront Park ](https://expedia.com/Riverfront-Park-Cape-Girardeau.d740677735274594304.Vacation-Attraction) - [Trail of Tears State Park ](https://expedia.com/Trail-Of-Tears-State-Park-Missouri.d553248621532655784.Vacation-Attraction) - [Cape Splash Family Aquatic Center ](https://expedia.com/Cape-Splash-Family-Aquatic-Center-Cape-Girardeau.d553248621532655772.Vacation-Attraction) - [eDen Spa & Salon ](https://expedia.com/EDen-Spa-Salon-Cape-Girardeau.d553248621532655776.Vacation-Attraction) - [Sikeston Depot Museum ](https://expedia.com/Sikeston-Depot-Museum-Sikeston.d6305602.Vacation-Attraction) - [Central Park ](https://expedia.com/Central-Park-Sikeston.d6305608.Vacation-Attraction) - [Cape Girardeau Conservation Nature Center ](https://expedia.com/Cape-Girardeau-Conservation-Nature-Center-Cape-Girardeau.d553248621532655773.Vacation-Attraction) - [Cape Rock Park ](https://expedia.com/Cape-Rock-Park-Cape-Girardeau.d553248621532655781.Vacation-Attraction) - [Fort D Historic Site ](https://expedia.com/Fort-D-Historic-Site-Cape-Girardeau.d553248621532655775.Vacation-Attraction) - [Litz Park ](https://expedia.com/Litz-Park-Jackson.d553248621554122991.Vacation-Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app