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$87 Cheap Flights to Santa Isabel

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Popular airlines to Santa Isabel

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How much is the cheapest flight to Santa Isabel?

Prices were available within the past 7 days and start at $87 for one-way flights and $165 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
LATAM Airlines Group
LATAM Airlines Group
Delta
United

What you need to know for your flight to Santa Isabel

Flights to Santa Isabel at a glance

Traveling to Santa Isabel is easy; you can choose between full-service and budget airlines. Just compare flight durations and select the best option that aligns with your budget, schedule, and plans to discover the city's renowned attractions and neighborhoods.

  • Major airports near Santa Isabel: Jose Joaquin de Olmedo International Airport (GYE), Mariscal Lamar Airport (CUE)
  • Closest airport to Santa Isabel: Mariscal Lamar Airport, CUE (around 35 miles)
  • Flights per week: 750+ flights arriving across Santa Isabel airports
  • Number of airlines that fly to Santa Isabel: around 10+ carriers

Popular airports near Santa Isabel

Santa Isabel is a vibrant city perfect for outdoor adventures, family trips, and eco-conscious vacations. Visitors are drawn to its stunning scenery, rich culture, and beautiful beaches. The city is conveniently accessible through two major airports.

  • Jose Joaquin de Olmedo International Airport (GYE): Situated in Guayaquil, Guayas, approximately 87 miles from Santa Isabel, this airport facilitates both domestic and international flights. It offers connections to about 4 domestic cities and over 70 international destinations. Travelers have the option to enhance their journey by upgrading to business or premium economy class seating, based on the airline and route. Major airlines operating here include Avianca, JetBlue Airways, and Copa.
  • Mariscal Lamar Airport (CUE): Found in Cuenca, Azuay, and located around 35 miles from Santa Isabel, this airport also caters to both domestic and international travel. It connects approximately 2 domestic cities and more than 10 international locations. For added comfort, passengers can opt for premium economy or business class seating, depending on their chosen airline and route. Key airlines serving this airport include LATAM Airlines Group, Avianca, and United.

Top routes to Santa Isabel

  • New York (JFK/LGA) to Santa Isabel (CUE/GYE), with one-way tickets available from around $170
  • Quito (UIO) to Santa Isabel (CUE/GYE), with one-way flight options from around $70
  • Miami (MIA) to Santa Isabel (CUE/GYE), with one-way fares starting at around $140
  • Newark (EWR) to Santa Isabel (CUE/GYE), with one-way flight options from around $160
  • Fort Lauderdale (FLL) to Santa Isabel (GYE), with one-way fares starting at around $95

Cheapest routes to Santa Isabel

  • Cuenca (CUE) to Santa Isabel (GYE), with low-cost one-way tickets from around $60
  • Guayaquil (GYE) to Santa Isabel (CUE), with affordable one-way prices from around $65
  • Quito (UIO) to Santa Isabel (CUE/GYE), with low-cost one-way tickets from around $70
  • Fort Lauderdale (FLL) to Santa Isabel (GYE), with cheap one-way fares from around $95
  • Austin (AUS) to Santa Isabel (GYE), with cheap one-way fares from around $120

*Flight times and fares vary by season and availability and are based on one-way routes

Top airlines with flights to Santa Isabel

  • Avianca: This airline operates flights to both Mariscal Lamar Airport (CUE) and Jose Joaquin de Olmedo International Airport (GYE), representing approximately 25% of arrivals in Santa Isabel. The typical one-way fare hovers around $320, with business class options available based on the specific route.
  • Copa: Serving Jose Joaquin de Olmedo International Airport (GYE), Copa Airlines makes up about 23% of Santa Isabel's arrivals. Average one-way ticket prices are around $340, and travelers may find premium cabins that include business class depending on the chosen route.
  • LATAM Airlines Group: Offering flights to Mariscal Lamar Airport (CUE) and Jose Joaquin de Olmedo International Airport (GYE), LATAM holds about 20% of the market for arrivals to Santa Isabel. The average fare for a one-way trip is roughly $340, with options for premium economy service on certain routes.
  • United: United Airlines provides service to both Mariscal Lamar Airport (CUE) and Jose Joaquin de Olmedo International Airport (GYE), accounting for around 11% of Santa Isabel's incoming flights. One-way fares typically average $340, with business class available as a premium cabin option based on the route.
  • JetBlue Airways: This airline flies into Jose Joaquin de Olmedo International Airport (GYE) and contributes about 9% of arrivals to Santa Isabel. Passengers can expect an average one-way fare of approximately $300, with premium economy seating potentially available depending on the route taken.

Best time to fly to Santa Isabel

The most popular months for travelers to fly to Santa Isabel are January, February, and March, when peak temperatures in Santa Isabel can reach up to 55.4°F in February. If you prefer quieter travel, consider September, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 53.8°F. For better deals, March usually offers the lowest average one-way fare around $281, roughly 11% cheaper than the yearly average. Looking for additional cheaper months to fly? October, April, and September offer average one-way fares of around $291, making them good options for flexible travelers.

calendar iconMonthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinesscrowd level iconDemandprice iconAverage one-way Fare
January55.0°F (12.8°C)Moderate RainMostly CloudyHigh$299
February55.4°F (13.0°C)Frequent RainMostly CloudyHigh$314
March54.7°F (12.6°C)Frequent RainMostly CloudyHigh$281
April54.1°F (12.3°C)Frequent RainMostly CloudyAverage$293
May53.2°F (11.8°C)Moderate RainMostly CloudyLow$301
June50.9°F (10.5°C)Moderate RainMostly CloudyAverage$327
July50.2°F (10.1°C)Moderate RainMostly CloudyAverage$351
August51.4°F (10.8°C)Light RainMostly CloudyAverage$320
September53.8°F (12.1°C)Light RainMostly SunnyLow$293
October55.6°F (13.1°C)Moderate RainMostly CloudyAverage$289
November56.3°F (13.5°C)Moderate RainMostly CloudyLow$313
December55.6°F (13.1°C)Moderate RainMostly CloudyAverage$447

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

How to save money on a flight to Santa Isabel

Getting some of the best deals on flights to Santa Isabel is all about timing and flexibility. Here are some key tips to help you save:

  1. Compare flight options—use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  2. Set up price alerts—as an Expedia member you can use Price Tracking to receive notifications when flight prices change.
  3. Bundle and save—book a flight and unlock a hotel deal on Expedia*, or explore our Santa Isabel hotel and flight deals.
  4. Think about luggage-nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your baggage allowance before confirming your booking to avoid excess baggage fees at the airport.
  5. Earn miles—you can earn airline miles when you book your Santa Isabel flight with Expedia. Just select your frequent flyer program and enter your program number when confirming your booking.

*For members. Select hotels.

Arriving in Santa Isabel

Santa Isabel welcomes travelers through its range of transport options based on price, convenience, and proximity. Here's how to reach Santa Isabel efficiently:

  • Public transportation: From Jose Joaquin de Olmedo International Airport, the Guayaquil Bus Terminal, a bus station, is located about 0.7 miles away on foot, while the Santa Rosa Seaport, a seaport, is approximately 0.9 miles away by car. For train travel, Duran Train Station, a train station, is situated about 4 miles from the airport, typically reached by car.
  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Santa Isabel, with private rides that can be arranged in advance.
  • Car rental: Renting a car in Santa Isabel is a good option if you plan to explore and sightsee beyond the city. Browse cheap car rentals in Santa Isabel on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.

Where to stay in and around Santa Isabel

  • Calvario: Nestled in the area of Santa Isabel, Calvario is a charming village perfect for a leisurely getaway. Travelers can enjoy the vibrant Santa Isabel Central Park, an ideal spot for families seeking outdoor fun. For nature enthusiasts, the impressive Carachulla rocks offer stunning scenery, while the Mirador de Turi church provides a glimpse into the local culture. Calvario's serene atmosphere makes it a delightful destination for those looking to unwind amidst beautiful landscapes.
  • San Fernando: Located 10 miles away from Santa Isabel, San Fernando is a scenic city that beckons outdoor lovers and adventure seekers. The breathtaking El Cajas National Park is a must-visit, offering vast landscapes for hiking and exploration. Busa Lagoon, known for its picturesque views, is another highlight, perfect for leisurely walks or picnics. The Mirador de Turi church also stands nearby, adding a cultural touch to your visit. San Fernando is especially lovely in the dry season, when the weather is ideal for outdoor activities.
  • Pacara: Situated 11 miles away from Santa Isabel, Pacara is a vibrant city offering a blend of urban parks and natural beauty. Visitors can relax at the Santa Isabel Central Park, a great place for family outings and leisure. The scenic Busa Lagoon invites travelers to enjoy the great outdoors, while the impressive Carachulla rocks provide a unique backdrop for exploration. Pacara's welcoming atmosphere makes it a fantastic stop for those seeking both tranquility and adventure in a captivating setting.

Tips for short-haul flights to Santa Isabel

For quick getaways, efficiency is key. Here is how to make your short-haul journey smoother:

  • Pack light and skip checked bags—with budget airlines, traveling with just a carry-on is often the more economical choice. Maximize space by using mini toiletries, wearing your heaviest clothes, and coordinating outfits in advance. This strategy also helps you avoid lengthy waits at baggage claim once you arrive.
  • Bring your own entertainment—many short-haul flights may lack in-flight entertainment options. To keep yourself occupied, download your favorite TV shows, movies, music, or podcasts beforehand, and don’t forget to bring a book. Be sure to fully charge your devices before boarding.
  • Arrive at the airport in plenty of time—even for short or domestic flights, it’s advisable to arrive at least 1.5 to 2 hours prior to departure, allowing for potential traffic and security delays.
  • Bring your own snacks and water—pack snacks and a reusable water bottle to stay hydrated and save money at the airport.

Tips for long-haul flights to Santa Isabel

Flying long-haul sometimes requires extra planning to ensure a comfortable journey:

  • Select your seat in advance—for longer flights, choosing your seat is essential for comfort. Full-service airlines often allow free seat selection once online check-in begins, typically 24–48 hours before your flight. Some airlines may permit seat selection even earlier.
  • Arrive at the airport in plenty of time—make it a point to arrive at the airport at least 3 hours before departure for international flights to accommodate check-in, security, and immigration processes.
  • Relax at the airport—if you have extra time, take the opportunity to browse the shops, grab a coffee, or unwind at the gate or in a departure lounge, if you have access. Most airports provide free Wi-Fi for your convenience.
  • Adjust to the new time zone mid-flight—begin syncing your body clock by changing your watch and modifying your sleep schedule to align with your destination's time zone. Aim to sleep or stay awake during the flight according to the local time at your arrival destination to help minimize jet lag.

Frequently asked questions

What month is the cheapest to fly to Santa Isabel?
Plan your trip for August if you want to land a deal on your fare. It's the cheapest month to fly to Santa Isabel. If possible, avoid traveling during peak periods such as public holidays or school breaks.
Which US cities fly direct to Santa Isabel?
If you'd rather fly to Santa Isabel directly, see what's on offer by selecting "Direct flights only" when you search for departures on Expedia.
How to find a cheap flight to Santa Isabel?
Traveling in the low season and booking ahead of time are two great ways to snag cheap flights to Santa Isabel. Or, consider departing on a Thursday, which, on average, is 16% cheaper than departing on a Sunday.* Want to be the first to know when fares fall? Just set up price tracking on the Expedia app for real-time updates.*Best day of the week to book, depart and ideal booking window recommendations based on average round-trip ticket prices for January through August 2023, sourced from Airline Reporting Corporation's (ARC) global airline sales database. Percentages noted are averages.
How to get a cheap last-minute flight to Santa Isabel?
Although booking in advance is typically the easiest way to save money, don't panic if your Santa Isabel trip is last minute. You can still find cheap flights to Santa Isabel, especially if your plans have some flexibility. Try switching up your dates, exploring different ticket types or jetting out of another hub.
How far in advance should I book a flight to Santa Isabel?
To snap up some of the best deals on domestic journeys, book your flight to Santa Isabel 28 days ahead of your travel dates. For international flights, it's between two and four months in advance. This boosts your chances of securing your preferred departure dates and seats.**Best day of the week to book, depart and ideal booking window recommendations based on average round-trip ticket prices for January through August 2023, sourced from Airline Reporting Corporation's (ARC) global airline sales database. Percentages noted are averages.
Which day of the week is the cheapest day to buy a plane ticket to Santa Isabel?
You can save an average of 8% if you purchase plane tickets on a Sunday rather than Fridays, which tend to be the priciest day to book.* When it comes to scoring a cheap flight to Santa Isabel, it's all about having good timing.*Best day of the week to book, depart and ideal booking window recommendations based on average round-trip ticket prices for January through August 2023, sourced from Airline Reporting Corporation's (ARC) global airline sales database. Percentages noted are averages.
Which airlines fly to Santa Isabel?
Two of the most well-known airlines to Santa Isabel are LATAM Airlines and AVIANCA. Altogether, 3 carriers connect Santa Isabel to 2 airports across the globe. Mariscal Lamar Airport (CUE) is the chief gateway to this exciting destination.
Where do you fly into Santa Isabel?
If you're flying to Santa Isabel, the main airport to jet into is Mariscal Lamar Airport (CUE). Alternatively, you could fly to Santa Isabel via General M. Serrano Airport (MCH).
How far is the airport from central Santa Isabel?
If you're flying into Mariscal Lamar Airport (CUE), you'll be roughly 35 mi northeast of central Santa Isabel.
Can I save money by booking a Santa Isabel trip package?
Bundle your accommodations and flights and you could save hundreds of dollars. What's more, you can add extras like car rentals and tours to your Santa Isabel flight and hotel package deal. With Expedia, it's simple to manage all your Santa Isabel travel plans in one place.
Can I change or cancel my flight to Santa Isabel?
If you bought your flight to Santa Isabel in the last 24 hours, you can typically cancel or change it for free. After that, additional costs may apply depending on the airline's terms and conditions. For more information, check out our Customer Service Portal. Bear in mind that some flights are non-refundable, so you may be offered a credit toward a future trip in place of a direct refund. During your search on Expedia, select the "Changes included" or "No cancel fee" boxes to compare tickets with flexible change policies.

*Flight schedules are subject to change.

*Available to One Key members.

Book with confidence

Tips to find the cheapest flights to Santa Isabel

The cheapest day to fly

Get started finding a cheap flight to Santa Isabel on Expedia by either choosing a deal on this page or entering into the search bar your travel dates, origin airport, and whether you want roundtrip or one-way airfare. You can filter for flexibility, number of stops, airline, and departure/arrival times to find the best flight for you.

The cheapest month to fly

August is the cheapest month to fly to Santa Isabel. This coincides with the low season when fewer people travel. Whichever month you travel in, though, be sure to book at least a month in advance if you want to score cheap tickets to Santa Isabel. ARC's data shows that domestic flights booked 28 days or more before departure are typically 24% cheaper than those booked last minute.

The most affordable time to book a flight

Typically, a Sunday can be the cheapest time to book a flight to Santa Isabel, according to ARC’s data. On average, you could save between 6% and 13% by booking on a Sunday instead of a Friday, which is the most expensive day to make a reservation.

The cheapest round-trip tickets to Santa Isabel

The lowest price for round-trip flights to Santa Isabel in 2026 starts from from $165, while one-way tickets start from from $87. Expedia's effective search tool is one of the best ways to find a budget airfare. Simply enter your dates, and within seconds, it'll show you a vast selection of the cheapest flights to Santa Isabel. If you have a preferred departure time or airline, you can use the handy filters to customize your search.

The cheapest airlines flying to Santa Isabel

LATAM Airlines Group, avianca, Delta, United are just some of the airlines that can typically offer cheap tickets to Santa Isabel. You can find their most affordable flights by using the “airline” search filter and then sorting prices from low to high. As a trusted partner of the world's leading airlines, Expedia offers you some of the best airfare deals to Santa Isabel and countless more destinations worldwide.

The most affordable airports to fly into

To view the cheapest airports to fly into for Santa Isabel, simply order your search results from lowest to highest price. Expedia's search tool compares flight prices for all airports close to your destination, so you don't have to manually search them one by one to find the cheapest flight to Santa Isabel. If you have a preferred place to fly into, take advantage of the “arrival airport” filter to narrow down your search on Expedia.

Save with a package

With Expedia's amazing package deals, you could save hundreds of dollars by booking your Santa Isabel plane tickets together with your accommodations, car rental, or activities. Just select the search wizard's “package” option to view some of the cheapest deals. Look out for the green savings label to see how much you're saving.

Date flexibility for the cheapest flights to Santa Isabel

If you can be flexible with your travel dates, it's a good idea to broaden your search by comparing prices on different days. This will open up more options, meaning you could uncover a less expensive flight to Santa Isabel.

Stopover savings

The cheapest tickets to Santa Isabel are sometimes those with a stopover. Book one of these flights, and you'll change planes at an airport en route to Santa Isabel. While the overall travel time might be longer than a non-stop flight, you may decide it's worth it for the money saved.

Get Expedia's Price Drop Protection

Price Drop Protection means that if your flight gets cheaper after booking, you'll be credited the difference*. This gives you peace of mind that you're getting one of the cheapest flights to Santa Isabel for your chosen departure. Expedia's Price Drop Protection is available for a small fee but is free to One Key Gold and Platinum tier members.

*Terms apply.

Use our Price Tracking feature

Expedia's Price Tracking feature is another great tool that removes the guesswork from finding cheap flights to Santa Isabel. Simply download the free Expedia app to your smart device and activate Santa Isabel flight price alerts for your travel dates. There's even a price predictor tool that uses historical data to indicate the best time to book, giving you peace of mind that you'll nab the lowest prices.

Book with Expedia

As well as Price Drop Protection and Price Tracking, Expedia's close partnership with a vast selection of the world's leading airlines means you're sure to find cheap flights to Santa Isabel. Plus, the One Key rewards program lets you earn real cash rewards on most bookings that you can use to save money on future trips. Best of all, it's free to join, and members often unlock exclusive discounts, too.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Tips to find the cheapest flights to Santa Isabel

Travel information

Destination airport
Mariscal Lamar
Destination airport IATA code
CUE
Destination city name
Cuenca
Roundtrip price
$164

Trending flights to Santa Isabel

Prices were available within the past 7 days and start at $87 for one-way flights and $165 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca

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