
Santa Isabel Vacations from $264
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $2,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Santa Isabel Vacation
Unforgettable adventures await when you book a Santa Isabel vacation package. Whether you're a foodie, history buff or just a traveler who loves discovering new places, there's something for everyone in this awesome city. When the time comes to get out and explore, be sure to include Santa Isabel Central Park and Carachulla on the itinerary for your trip to Santa Isabel. Whoever you're traveling with and whatever your bank balance, your dream Santa Isabel vacation is just clicks away with Expedia.
The Latest Santa Isabel vacation packages
Price found within the past 48 hours. Click for updated prices.


Uzhupud Garden Hotel & lodge
Price was $559, price is now $432 per person
$432
per person
Dec 26 - Dec 30
found 1 day ago
Roundtrip flight included
Guayaquil (GYE) to Cuenca (CUE)
8.6/10 Excellent! (40 reviews)
Cuarto limpio, desayuno buffet del domingo muy bueno. La de los otros días, muy básico, no acorde con el estándar de un hotel de esas características. Si bien la atención del front desk fue buena, hubo momentos en que no había nadie en la recepción. En términos generales, una estadía placentera.
Reviewed on Apr 17, 2026


Killary Lodge
Price was $463, price is now $400 per person
$400
per person
Dec 26 - Dec 30
found 1 day ago
Roundtrip flight included
Guayaquil (GYE) to Cuenca (CUE)
9.8/10 Exceptional! (7 reviews)
A nice quiet getaway about 35 minutes from Cuenca. Surrounded by nature, enabling one to go for walks. It is a family run place and the hosts are very friendly and helpful.
Reviewed on Mar 5, 2026

Don't see what you're looking for?
See all available trips from Columbus to Santa Isabel
View all tripsStay near popular Santa Isabel attractions
Santa Isabel Hotel Deals

Inti Kamari- Wellness Lodge, Spa & Retreats
Entrada a Quillosisa Alto Santa Isabel Azuay
$168 nightly
The price is $168 total per night from Nov 27 to Nov 28
$168 total
Nov 27 - Nov 28

Modern Country House with Heated Pool in Yunguilla Valley Near Cuenca Ecuador
Santa Isabel Azuay
Fully refundable
$311 nightly
The price is $311 total per night from Nov 16 to Nov 17
$311 total
Nov 16 - Nov 17

El Prado Glamping
Panamericana E35 El Tablón Loja Province
10/10 Exceptional! (1 review)
"Un lugar hermoso, solo falta dar mas opciones para el check in"
Reviewed on Apr 8, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Santa Isabel Vacation Packages
Santa Isabel Essential Information
Language | Spanish |
|---|---|
Currency | U.S dollars |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Max Temp Winter | 60ºF |
Max Temp Summer | 60ºF |
Top Sights | Santa Isabel Central Park and Carachulla |
More vacations you might like
Frequently asked questions
Explore a world of travel with Expedia
- Hotels in Santa Isabel
- 5 Star Hotels in Santa Isabel
- Hostels in Giron
- 3 Star Hotels in San Fernando
- Hotels in San Fernando
- Apartments in Nabon
- Hotels in Calvario
- Private Vacation Homes in Giron
- Hotels in Giron
- Hotels in Pacara
- Hotels in Nabon
- 4 Star Hotels in Pacara
- 2 Star Hotels in Pacara
- 5 Star Hotels in San Fernando
- 3 Star Hotels in Nabon
- Hotels in Caledonias
- 2 Star Hotels in Nabon
- 4 Star Hotels in Nabon
- 5 Star Hotels in Pacara
- Car rentals in Santa Isabel
- ADA Rental Cars in Santa Isabel
- Convertible Car Rentals in Giron
- Unidas Rental Cars in Santa Isabel
- Car rentals in Caledonias
- Minivan Car Rentals in Giron
- Car rentals in Calvario
- Car rentals in San Fernando
- Car rentals in Pacara
- Car rentals in Giron
- Avis Rental Cars in Santa Isabel
- Mid Size Car Rentals in Giron
- Goldcar Key’n Go Rental Cars in Santa Isabel
- AirCar Car Rental Cars in Giron
- Economy Rent a Car Rental Cars in Giron
- Car rentals in Nabon
- Top Rent a Car Rental Cars in Giron
- Drive on Holidays Rental Cars in Giron
- Sixt Ni Rental Cars in Giron
- National Car Rental Cars in Giron
- Keddy By Europcar Rental Cars in Giron
- Localiza Argentina Rental Cars in Giron
- ACE New Zealand Rental Cars in Santa Isabel
- Avis Canaries Rental Cars in Santa Isabel
- Click & Rent Rental Cars in Santa Isabel
- Europcar Rental Cars in Santa Isabel
- Get Your Car Rental Cars in Santa Isabel
- Guerin Rental Cars in Santa Isabel
- Hertz Rental Cars in Santa Isabel
- Localiza Uruguay Rental Cars in Santa Isabel
- First Car Rental Cars in Giron
- Localiza Rental Cars in Giron
- SR Rent A Car Rental Cars in Giron
- Maggiore Rental Cars in Nabon
- Goldcar Key’n Go Rental Cars in Giron
- Keddy By Europcar Rental Cars in Santa Isabel
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.



















