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10 cruises found - Prices are per traveler, available within last 24 hours and valid for US and Canadian residents only. Taxes, fees, and port expenses are included. Fuel supplement may apply.
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Zaandam

4 night Pacific Coastal

Holland America Line
Holland America Line • Zaandam
May 3, 2025 — May 7, 2025
San Diego, United States • Avalon (Catalina Island), United States • Vancouver, CanadaDeparting from San Diego, visiting 3 ports, select Itinerary details to review day by day itinerary

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Nieuw Amsterdam

4 night Pacific Coastal

Holland America Line
Holland America Line • Nieuw Amsterdam
Apr 30, 2025 — May 4, 2025
San Diego, United States • Victoria Airport, Canada • Vancouver, CanadaDeparting from San Diego, visiting 3 ports, select Itinerary details to review day by day itinerary

inside room per traveler
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Eurodam

6 night Pacific Coastal

Holland America Line
Holland America Line • Eurodam
Apr 26, 2025 — May 2, 2025
San Diego, United States • San Francisco, United States • Victoria Airport, Canada • Vancouver, CanadaDeparting from San Diego, visiting 4 ports, select Itinerary details to review day by day itinerary

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Norwegian Jade

6 night Mexico

Norwegian Cruise Line
Norwegian Cruise Line • Norwegian Jade
Nov 2, 2025 — Nov 8, 2025
San Diego, United States • Los Cabos, Mexico • La Paz, Mexico • San Diego, United StatesDeparting from San Diego, visiting 4 ports, select Itinerary details to review day by day itinerary

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Koningsdam

4 night Pacific Coastal

Holland America Line
Holland America Line • Koningsdam
Oct 21, 2025 — Oct 25, 2025
San Diego, United States • Santa Barbara, United States • Avalon (Catalina Island), United States • Ensenada, Mexico • San Diego, United StatesDeparting from San Diego, visiting 5 ports, select Itinerary details to review day by day itinerary

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Norwegian Jade

7 night Mexico

Norwegian Cruise Line
Norwegian Cruise Line • Norwegian Jade
Nov 8, 2025 — Nov 15, 2025
San Diego, United States • Los Cabos, Mexico • Mazatlan, Mexico • Puerto Vallarta, Mexico • San Diego, United StatesDeparting from San Diego, visiting 5 ports, select Itinerary details to review day by day itinerary

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Norwegian Jade

7 night Mexico

Norwegian Cruise Line
Norwegian Cruise Line • Norwegian Jade
Dec 6, 2025 — Dec 13, 2025
San Diego, United States • Los Cabos, Mexico • Mazatlan, Mexico • Puerto Vallarta, Mexico • San Diego, United StatesDeparting from San Diego, visiting 5 ports, select Itinerary details to review day by day itinerary

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Norwegian Jade

7 night Mexico

Norwegian Cruise Line
Norwegian Cruise Line • Norwegian Jade
Dec 13, 2025 — Dec 20, 2025
San Diego, United States • Los Cabos, Mexico • Mazatlan, Mexico • Puerto Vallarta, Mexico • San Diego, United StatesDeparting from San Diego, visiting 5 ports, select Itinerary details to review day by day itinerary

inside room per traveler
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Norwegian Jade

5 night Mexico

Norwegian Cruise Line
Norwegian Cruise Line • Norwegian Jade
Feb 7, 2026 — Feb 12, 2026
San Diego, United States • Los Cabos, Mexico • San Diego, United StatesDeparting from San Diego, visiting 3 ports, select Itinerary details to review day by day itinerary

inside room per traveler
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Norwegian Jade

7 night Mexico

Norwegian Cruise Line
Norwegian Cruise Line • Norwegian Jade
Oct 26, 2025 — Nov 2, 2025
San Diego, United States • Los Cabos, Mexico • Mazatlan, Mexico • Puerto Vallarta, Mexico • San Diego, United StatesDeparting from San Diego, visiting 5 ports, select Itinerary details to review day by day itinerary

inside room per traveler
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Find a great cruise from San Diego

What are the best cruises from San Diego?

When you choose to cruise from San Diego, you have a lot of options. Many San Diego cruise lines offer curated experiences for travelers, and most cruise lines from San Diego have options that will work for almost any schedule and budget. Royal Caribbean cruise line from San Diego is one that is very popular with travelers of all ages, offering upscale amenities and many options for cabin size and onboard refreshments. The best cruise line out of San Diego is one that suits your needs and vacation plans, and you are sure to find it when you book with Expedia.

 

How can I find a cheap San Diego cruise?

Cheap cruises out of San Diego are easy to find through the Expedia website. You can find 2-night cruise from San Diego, or even 7 day cruises from San Diego on the Expedia website. When you are looking up your San Diego cruise, filter the results by price so that the lowest-priced cruises display at the top of the page. The most expensive cruises will be listed at the bottom of the page. When you find the cheap San Diego cruise that fits your criteria, you can book it directly from the Expedia page, saving you time and money.

 

What cruise lines operate from San Diego?

There are a multitude of cruise ships leaving from San Diego, including Disney, Carnival, and Princess cruise lines. While specific cruise packages and offerings will change on a week-to-week basis, at any time of the year you are likely to have a lot of options when you search for San Diego cruises on the Expedia website. There are so many cruises leaving from San Diego that you can surely find your next destination.

 

How can I find good cruise deals out of San Diego?

You might be working with a set budget as you try to plan your cruise from San Diego 2025. This doesn't mean you have to compromise on any part of your cruise vacation, however. The quickest way to find a good deal on a San Diego cruise is to sort your search results by price so that the lowest-priced cruise will display at the top of the page. However, you can also score good deals on a cruise trip by signing up for emails and promotions from Expedia. This way, you will get alerted when exclusive cruise deals from San Diego are available.

 

What to look out for when you book your San Diego cruise?

If you've experienced San Diego cruise ships before, you might know exactly what you want, and you are familiar with some of the best cruises out of San Diego. If you are new to cruise ships, however, you will want to pay special attention to the What's Included section on the Expedia website. This will list all the special amenities that the cruise ship offers, including programs hosted on the deck, cabin sizes, and any other special offerings and perks that you will need to be aware of. You should also take special note of the dates that the San Diego cruise makes port so that you can be sure it aligns with your plans.

 

Where are the best places to go on a cruise from San Diego in 2025?

Cruises from San Diego stop at a wide variety of exciting and beautiful destinations. From cruises to Mexico, where travelers can enjoy white sandy beaches, to cruises from San Diego to Alaska, where those on board can discover incredible natural beauty, there are many spectacular places to go on a cruise from San Diego. If you don't have a specific city in mind for your cruise from San Diego, try choosing somewhere new - you might be surprised to discover your new favorite city or destination.

 

What are some great weekend cruises from San Diego?

If you don't have a lot of time but still want to enjoy a fabulous cruise vacation, you can look into weekend cruises from San Diego. Royal Caribbean cruise line offers several luxury cruise ships that run two-day cruises. These weekend cruises pack a lot of fun and exciting amenities into one weekend so that you will be able to enjoy all the perks of a cruise vacation without an extensive time commitment. If you ever want to quickly find a weekend cruise out of San Diego 2025 , log onto Expedia and enter your desired date of departure and the desired length of your cruise. You will see all available options on the screen, so you will be able to tell at a glance if there's a weekend cruise that works well for you.

 

How to book a cruise from San Diego on Expedia?

It's easy to use Expedia to book your 2025 San Diego cruise. First, do a search on the Expedia website for cruises that dock in San Diego. If you are working with set dates for departure, enter those as well. You should then see a list of all available San Diego cruises for the dates you selected. You can then check all the available amenities on the cruise you select, and if it meets your needs, you can book it directly on the Expedia website.

 

What are some great gay cruises from San Diego?

Members of the LGBTQ+ community can always find a fantastic cruise from San Diego. Most of the top cruise lines out of San Diego, including Cunard cruise line, offer cruises that are perfect for anyone seeking a gay cruise. Specialized amenities, community events, and fun food and drinks packages will keep passengers entertained, as well as onboard performances such as live music and singing that will ensure that your San Diego gay cruise is truly memorable.

 

How can I find last-minute cruise deals from San Diego?

If you find yourself with some extra time on your hands and want to enjoy some rest and relaxation on the open ocean, a last-minute cruise deal from San Diego could be just the ticket. To find one of these deals, just search on the Expedia site “last-minute cruise deals San Diego”, or by entering the date of your departure and your port of departure. You should be presented with a list of options for available cruises. The green box with the price on top of the standard cruise price will represent the savings that you will enjoy on that particular cruise.

 

Do you need a passport to cruise from San Diego?

Depending on your travel plans, you may or may not need a passport for cruises departing out of San Diego. If you are a United States citizen, and if your cruise ship isn't planning a stop at any city or destination outside of the US, you shouldn't need a passport. However, if your cruise will be docking at a place like the Middle East or Bermuda, you will likely need to have your passport on hand. In general, it's a good idea to contact your travel agent (if you have one) or reach out to Expedia's customer service team for specific questions about travel arrangements.

 

Can I cancel my cruise booking?

Plans change from time to time and you might find that you need to cancel a ticket booked on a cruise ship from San Diego. When that happens, you have options. Expedia makes it easy to cancel your cruise. Simply log into your Expedia account and navigate to the My Trips page, where you can select the trip that you wish to cancel. From there, you can follow the steps outlined on the page to cancel the cruise. Make sure that you've received a confirmation email as a final step in the process. If you have any questions about the cancelation process, you can reach out to Expedia's customer service team for an answer. Another thing to note is that you might not be eligible for a full refund on your canceled cruise, depending on the policies of the specific cruise line.

 

Why should I book a cruise from San Diego with Expedia?

There's no better way to see and explore San Diego than through an Expedia cruise. When you are looking for San Diego Cruises 2025, look no further than Expedia. Expedia offers all the perks and special amenities that a cruise traveler could hope for, as well as a wealth of options that are easy to explore directly on the Expedia website. Expedia also allows you to book multiple things for your trip at once, including a rental car, hotel, and flights.

 

San Diego Cruise Guide

San Diego is called “America’s Finest City,” and for good reason – this Southern California cruise port maintains a mild, enjoyable climate all year round. Whether it’s Summer or Winter, you’ll always find sunshine and chill beach vibes, making it a good port to extend your cruise vacation.

Depending on the season, you can find a variety of cruise deals and getaways. In the winter, cruise to sunny itineraries including Hawaii, Australia, Mexico, or South America. From January to April you can find many departures to the Pacific Coast, the Mexican Riviera, Hawaii, and South America.

From the International Cruise Ship Terminal, you can walk along the beautiful bayside promenade to explore the chic shops and restaurants. You’ll also find an assortment of family-friendly attractions, like the USS Midway Museum and the Maritime Museum, which are just a 5-minute walk from the International Cruise Ship Terminal. Across from the museums you’ll find the Waterfront Park, a 12-acre plaza equipped with playgrounds, a large fountain, and seaside views. A quick 15 to 20-minute drive into the city takes you to the San Diego Zoo and Safari Park, as well as SeaWorld, which are all part of the giant urban complex of museums and gardens known as Balboa Park. You can also take a sea lion excursion or go snorkeling in one of the many beaches sprawled out along the San Diego bay.

The San Diego food scene is very diverse, with dozens of options all along San Diego’s bayfront. There’s the Fish Market, several Mexican-inspired restaurants, steakhouses, sushi, and a lot of local farm-to-table cuisine, supporting local farms and serving up the freshest culinary bites. There’s also a growing selection of local craft breweries, with hundreds spread out throughout the city, making it the craft brewing capital of North America. There's a lot of ways you can spend your days - and nights - at "America's Finest City," making it an awesome choose-your-own-adventure experience!

Pre and Post Cruise Hotels in San Diego

Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S, San Diego, CA
The price is $104 per night from Mar 19 to Mar 20
$104
includes taxes & fees
$93 per night
Mar 19 - Mar 20
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
8.6/10 Excellent! (3,034 reviews)
"Close to freeways"

Reviewed on Mar 13, 2025

Kings Inn San Diego
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
The price is $124 per night from Mar 17 to Mar 18
$124
includes taxes & fees
$110 per night
Mar 17 - Mar 18
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
7.8/10 Good! (1,625 reviews)
"It was quaint"

Reviewed on Mar 16, 2025

Handlery Hotel
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4 out of 5
875 Hotel Circle South, San Diego, CA
The price is $202 per night from Mar 31 to Apr 1
$202
includes taxes & fees
$179 per night
Mar 31 - Apr 1
Stay at this 4-star spa hotel in San Diego. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
9/10 Wonderful! (2,861 reviews)
"Just as above"

Reviewed on Mar 14, 2025

Legacy Resort Hotel & Spa
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Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr, San Diego, CA
The price is $157 per night from Mar 17 to Mar 18
$157
includes taxes & fees
$139 per night
Mar 17 - Mar 18
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant ...
9/10 Wonderful! (2,394 reviews)
"Loved our stay here. my boyfriend and I stayed here for 2 nights and was absolutly amazing. the view from our room was gorgeous and is in an amazing area its super quiet with lots of dining options around so much to do in this area"

Reviewed on Mar 11, 2025

Bay Club Hotel & Marina
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

2.5 out of 5
2485 Hotel Circle Place, San Diego, CA
The price is $144 per night from Mar 24 to Mar 25
$144
includes taxes & fees
$127 per night
Mar 24 - Mar 25
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (1,349 reviews)
"Overall, great stay. I will say, the LED property lights should be pointed down instead of directly into rooms. Hot tub was very nice. There is covered parking for an additional fee. Also, housekeeping shares the elevator with guests and that was a little inconvenient."

Reviewed on Mar 15, 2025

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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