Cheap Hotels in Defiance, MO from $74
Check availability on Defiance Cheap Hotels
Our top choices for Defiance cheap hotels
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport WestMaryland Heights
7.4 out of 10, Good, (1001)
"Clean lobby, super friendly staff, effortless check in. There’s even a small market with food and essentials right next to the check in desk. "
Jen
$64 nightly
The price is $74
Jan 5 - Jan 6, 2026
Total with taxes and fees
8.4 out of 10, Very Good, (2218)
"Front staff was very friendly and very helpful. Check-in and check out was smooth and very easy. "
James
$117 nightly
The price is $137
Jan 6 - Jan 7, 2026
Total with taxes and fees
7.6 out of 10, Good, (1001)
"Great front desk experience, no issues booking same day!"
Tracy
$78 nightly
The price is $92
Jan 4 - Jan 5, 2026
Total with taxes and fees
8.0 out of 10, Very Good, (1007)
"Great staff, clean room. "
Amanda
$87 nightly
The price is $100
Dec 21 - Dec 22
Total with taxes and fees
Sleep Inn & Suites O'Fallon MO - Technology Drive
Sleep Inn & Suites O'Fallon MO - Technology DriveO'Fallon
8.8 out of 10, Excellent, (1001)
"Nice breakfast, friendly staff"
Damon
$83 nightly
The price is $97
Dec 15 - Dec 16
Total with taxes and fees
7.4 out of 10, Good, (1002)
"Everything was nice"
Ronald
$90 nightly
The price is $104
Jan 4 - Jan 5, 2026
Total with taxes and fees
8.4 out of 10, Very Good, (1004)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
Robyn
$166 nightly
The price is $194
Dec 14 - Dec 15
Total with taxes and fees
9.2 out of 10, Wonderful, (170)
"Clean room, nice staff, great food, and great service "
Thuy
$105 nightly
The price is $121
Dec 14 - Dec 15
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find out more about Defiance
How can I get cheap hotels in Defiance?
Best tips to find a cheap hotel in Defiance
- If you're looking to travel to Defiance on a budget, you'll be happy to know that you can find hotels for as low as $74. Of course, that price is affected by amenities, star rating, and even the time of year you visit. At most, hotel prices can be as high as $194. Staying a short amount of time in Defiance is an effective way to reduce hotel costs.
- When you cut your vacation down to just a few days, you don't have to worry as much about hotel prices since you don't have that many nights to stay. For budget hotels in Defiance, 3 to 4 days should be all the nights you need. That's generally enough to enjoy the city's top attractions, though there's certainly enough to do to warrant a week-long trip.
- When booking cheap hotel rooms in Defiance, it's typically best to book about 3 weeks in advance. Book further in advance than that and you could be paying too much for your room, as hotels will often overestimate future demand. However, if you wait too long, you might find that the hotel has been completely booked.
- When you utilize search filters on Expedia, you'll be able to narrow down your results in a flash. These search filters cover a wide variety of factors you may be interested in when it comes to finding a cheap hotel in Defiance, including amenities such as Free Breakfast, 2-star rating, or proximity to local attractions. You can even set filters for price limits to ensure that all the displayed results are within your budget.
Top Defiance Hotel Reviews
Country Inn & Suites by Radisson, St. Charles Historic District
10/10 Excellent
Frequently asked questions
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- Yellow Farmhouse Winery
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- Historic Daniel Boone Home and Heritage Center
- Babler State Park
- Dr. Edmund A. Babler Memorial State Park
- Weldon Spring Site Interpretive Center
- Montelle Winery
- August A. Busch Memorial Conservation Area
- Broemmelsiek Park
- Augusta Vacations
- Visit Weldon Spring Heights
- St. Louis Premium Outlets
- Missouri Bluffs Golf Course
- Augusta Winery
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