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Vacation Rentals in New Madrid County

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Top Cities in New Madrid County

A tree with sunlight filtering through its leaves, creating a warm glow.
Vacation RentalsVacation Rentals

Sikeston

Sikeston
A cannon on a brick platform by a river, with a steamboat in the background.
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New Madrid

New Madrid

Our top choices for New Madrid County vacation rentals

A single-story house with a gabled roof, a front porch with two chairs, and a front door with a decorative glass panel.

1. Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
New Madrid
10.0 out of 10, Exceptional, (1 review)
"The host was very quick to respond and so great to work with for on our stay. "
United States
Jessica S.
$311 nightly
The price is $339
Nov 6 - Nov 7
Total with taxes and fees
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
A covered outdoor seating area with stone flooring and chairs, a stone pathway, and a wooden structure.

2. Vacation rental attached to our house out in the country.

Vacation rental attached to our house out in the country.
Union City
10.0 out of 10, Exceptional, (9 reviews)
"The home was spotless, very comfortable and a great location for what we needed."
United States
Sherrie S.
$137 nightly
The price is $154
Nov 6 - Nov 7
Total with taxes and fees
Vacation rental attached to our house out in the country.
A living room with a wooden table, a fireplace, a television, and a bookshelf.

3. Secluded Shop-House Retreat - Walk to Heritage Park!

Secluded Shop-House Retreat - Walk to Heritage Park!
Piggott
10.0 out of 10, Exceptional, (1 review)
"The location—a pleasant walk to Heritage Park—is quiet, shaded, and easy to get to. The host had little extra amenities waiting for us and we appreciated the stress-free getaway."
United States
Lynette H.
$164 nightly
The price is $184
Dec 1 - Dec 2
Total with taxes and fees
Secluded Shop-House Retreat - Walk to Heritage Park!
A modern kitchen with stainless steel appliances, wooden cabinets, and a white countertop.

4. The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO

The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO
Dexter
10.0 out of 10, Exceptional, (4 reviews)
"Perfect place for our stay on the way to North Carolina! Clean, cozy and convenient!"
United States
Robert G.
$152 nightly
The price is $164
Nov 8 - Nov 9
Total with taxes and fees
The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO
A kitchen with a marble countertop, wooden cabinets, and deer antlers mounted on the wall.

5. Cozy rustic studio near Reelfoot Lake

Cozy rustic studio near Reelfoot Lake
Troy
10.0 out of 10, Exceptional, (1 review)
"Was awesome found this last min b4 we left town"
United States
Gary G.
$129 nightly
The price is $145
Nov 12 - Nov 13
Total with taxes and fees
Cozy rustic studio near Reelfoot Lake
A wooden interior with a herringbone floor, a sliding barn door, a wooden door with a glass panel, and a window with blinds.

6. Tiny house on the lake with tv free internet walk shower

Tiny house on the lake with tv free internet walk shower
Tiptonville
10.0 out of 10, Exceptional, (1 review)
"Dave was very accommodating and the home was clean."
United States
Katherine P.
$259 nightly
The price is $294
Nov 6 - Nov 7
Total with taxes and fees
Tiny house on the lake with tv free internet walk shower
A cozy living room with two leather sofas, a stone wall, wooden ceiling, and a large sliding glass door leading to an outdoor deck.

7. Doc's Cottage - A-Frame in Piggott, AR

Doc's Cottage - A-Frame in Piggott, AR
Piggott
10.0 out of 10, Exceptional, (16 reviews)
"A comfortable place to visit in my home town and catch up with local family members."
United States
Mary C.
$220 nightly
The price is $245
Nov 8 - Nov 9
Total with taxes and fees
Doc's Cottage - A-Frame in Piggott, AR
A two-story house with a front porch, a covered entryway, and a small garden with white flowers.

8. Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy
Dexter
7.8 out of 10, Good, (39 reviews)
"Overall, it was a good experience. I would stay again."
United States
Tammy G.
$191 nightly
The price is $206
Nov 8 - Nov 9
Total with taxes and fees
Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy
A wooden structure with a porch, labeled "1086", and a sign advertising nightly rentals at "The Hut II" with contact information.

9. The Hut II on Reelfoot Lake

The Hut II on Reelfoot Lake
Hornbeak
9.8 out of 10, Exceptional, (11 reviews)
"It’s one of our favorite places to stay. "
United States
Laura W.
$212 nightly
The price is $239
Nov 29 - Nov 30
Total with taxes and fees
The Hut II on Reelfoot Lake
A small, single-story mobile home with a covered porch and a sign that reads "THE HUT".

10. The Hut. Cozy 2-bedroom mobile home on peaceful Reelfoot Lake with boat shed

The Hut. Cozy 2-bedroom mobile home on peaceful Reelfoot Lake with boat shed
Hornbeak
9.8 out of 10, Exceptional, (60 reviews)
"Very clean and cozy…def will be back"
United States
Ronnie V.
$228 nightly
The price is $257
Nov 29 - Nov 30
Total with taxes and fees
The Hut. Cozy 2-bedroom mobile home on peaceful Reelfoot Lake with boat shed
A covered outdoor area with a grill, chairs, and a table.

11. Come and relax at the Refuge at beautiful Reelfoot Lake!

Come and relax at the Refuge at beautiful Reelfoot Lake!
Hornbeak
9.4 out of 10, Exceptional, (37 reviews)
"Location was great. We were down for a few days fishing."
United States
Andrew
$213 nightly
The price is $241
Dec 6 - Dec 7
Total with taxes and fees
Come and relax at the Refuge at beautiful Reelfoot Lake!
A kitchen with a stainless steel stove, a range hood, wooden cabinets, and a herringbone wood backsplash.

12. Charming 3-bedroom house with free wifi and coffee it is close to the lake

Charming 3-bedroom house with free wifi and coffee it is close to the lake
Hornbeak
10.0 out of 10, Exceptional, (11 reviews)
"This place was great! It has everything you need and the neighborhood was quiet. The beautiful view of the lake makes it very peaceful! "
United States
Jamie M.
$226 nightly
The price is $255
Nov 8 - Nov 9
Total with taxes and fees
Charming 3-bedroom house with free wifi and coffee it is close to the lake
A covered patio with a white bench, a glass table, and a fan.

13. Fish cleaning station, screened porch, covered front porch, fire pit, 3 BR

Fish cleaning station, screened porch, covered front porch, fire pit, 3 BR
Hornbeak
9.8 out of 10, Exceptional, (63 reviews)
"Very clean and very helpful host"
United States
Whitney C.
$235 nightly
The price is $266
Nov 8 - Nov 9
Total with taxes and fees
Fish cleaning station, screened porch, covered front porch, fire pit, 3 BR
A modern kitchen with a central island, bar stools, stainless steel appliances, and wooden flooring.

14. The Morning Glory - Country Cottage

The Morning Glory - Country Cottage
Piggott
10.0 out of 10, Exceptional, (9 reviews)
"House was clean and had everything we needed for a comfortable stay!"
United States
Justin C.
$237 nightly
The price is $260
Dec 6 - Dec 7
Total with taxes and fees
The Morning Glory - Country Cottage
A wooden interior with a dining table, chairs, a sofa, and a fireplace.

15. 3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters

3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters
Hornbeak
10.0 out of 10, Exceptional, (16 reviews)
"Great place to stay"
United States
Steve H.
$363 nightly
The price is $411
Nov 8 - Nov 9
Total with taxes and fees
3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters
A large, single-story building with two open garage-style doors, surrounded by trees with autumn foliage.

16. Guest house and spacious shop located between Discovery Park and Reelfoot Lake

Guest house and spacious shop located between Discovery Park and Reelfoot Lake
Union City
10.0 out of 10, Exceptional, (3 reviews)
"Wonderful place to relax. Home has everything you need. The additional party barn is an added bonus!!"
United States
william P.
$328 nightly
The price is $370
Nov 6 - Nov 7
Total with taxes and fees
Guest house and spacious shop located between Discovery Park and Reelfoot Lake
A bedroom with a bed, a dresser, a television, and a small table with a plant.

17. Sunkist beach house. Lake side house 3 bedroom house

Sunkist beach house. Lake side house 3 bedroom house
Tiptonville
10.0 out of 10, Exceptional, (5 reviews)
"Great experience!! A quality stay with great communication from Host. Will be back! "
United States
Steven L.
$295 nightly
The price is $337
Nov 6 - Nov 7
Total with taxes and fees
Sunkist beach house. Lake side house 3 bedroom house
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top New Madrid County Hotel Reviews

Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

8/10 Good
"I didn’t like that the room we stayed in, the bathroom was not serviced/cleaned daily. The cleaning was only every other day. I’m okay with every other day full cleaning but would really like daily bathroom cleaning. The gym was very nice. The breakfast is okay, not great but definitely not the worst we’ve had. Overall the hotel is clean and well maintained. In Dexter I believe this is the best hotel option available."
Tila L 3-night trip
Posted 2 days ago
Hampton Inn By Hilton Dexter

Find out more about New Madrid County

Discover your perfect New Madrid County vacation rental with Expedia

How many vacation rentals are available in New Madrid County?


Expedia has plenty of vacation rentals to choose from in and around  New Madrid County, so you’re guaranteed to find the right one for you. 


How much is a vacation rental in New Madrid County?


The selection of New Madrid County vacation rentals we have selected for you start as low as $154 per night. Entering your travel dates in the search wizard you might find even better deals!


What type of vacation rental can I get in New Madrid County?


Vacation rentals in New Madrid County come in all shapes and sizes, and your options depend on your chosen travel dates. You could entertain in a blissful vacation home, chill in a private apartment, or find family fun at a resort. Expedia offers a superb choice of New Madrid County vacation rentals to suit everyone. 


Why should I choose a vacation rental in New Madrid County?


Expedia’s vacation rentals provide cozy comforts you can sink into on your own schedule. You’ll enjoy your own space in a property with a kitchen, a pool, a garden etc. Maybe you’ll prefer somewhere with a spa or kids activities. A New Madrid County vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in. 


How do I find the best deal on a vacation rental in New Madrid County?


Find vacation rentals in New Madrid County by viewing Expedia’s latest deals, or enter your travel dates and use the filters to select by amenities, price, or rating. Dive into the reviews to get a true feeling of which is your favorite vacation rental in New Madrid County.  


What amenities are available in a vacation rental in New Madrid County?


The choice is yours! Perhaps you love cooking in a well-equipped kitchen. Or maybe a late breakfast and a swimming pool is more your thing. Of course, there’s always the treat of having your own hot tub. Expedia has a vast range of amenities in New Madrid County vacation rentals designed to suit every budget and trip type.


When is the best time to stay in a vacation rental in New Madrid County?   


Everytime is a great time to head to New Madrid County! Staying in a New Madrid County vacation rentals you will always find lots going on to keep you entertained. 


Why book a vacation rental with Expedia?


Expedia has locked in amazing deals on a huge selection of impressive vacation rentals in New Madrid County. We give you the information and inspiration you need all in one place. With so many properties to choose from, you know you can book your perfect New Madrid County vacation rental with confidence. ANd don’t forget, if you bundle with a flight or a car rental in New Madrid County, you can save even more.


Can I cancel my vacation rental through Expedia?  


Yes, you can cancel or change your New Madrid County vacation rental by contacting your property manager directly. Contact details are easy to find on your itinerary in Trips. For more information, check out our Customer Service Portal and we’ll help you get everything sorted.