Name: Megapolis Hotel Panamá
Price range: $239 total
Rating: 8.4

Your Distrito Colón Vacation

Set off on your next thrilling adventure with a Distrito Colón vacation package, and leave relaxed knowing the finer details are organized. And with the ability to tailor your escape, you know it'll be one to remember. A trip to Distrito Colón wouldn't be complete without spending a day or two in Colon. This city is among the top places to visit here. Expedia is a one-stop shop for organizing your Distrito Colón vacation. From hotels and flights, to activities and more, we know how to curate a travel experience like no other.

Top destinations in Distrito Colón

The Latest Distrito Colón Vacation Packages

Price found within the past 48 hours. Click for updated prices.

Mahogany Suites

$719

per person

Mar 16 - Mar 23

found 20 hours ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

10/10 Exceptional! (1 review)

Room was spotless, front gate staff was really nice, loved the tiny gym on the main floor.

Reviewed on Dec 21, 2025

Central Hotel Panama Casco Viejo

Casco Viejo

Save 100% on your flight

$1,553

per person

Mar 16 - Mar 23

found 20 hours ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

9/10 Wonderful! (1,002 reviews)

Breakfast and live music was excellent.

Reviewed on Jan 7, 2026

Villa Botero By Casa Mojito B&B

Save 100% on your flight

$1,012

per person

Feb 27 - Mar 8

found 19 hours ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

9.8/10 Exceptional! (60 reviews)

Host was excellent. Great communication and very helpful. The rooms were nice and great value.

Reviewed on Apr 18, 2025

Megapolis Hotel Panamá

San Francisco

Save 100% on your flight

$1,261

per person

Mar 16 - Mar 23

found 20 hours ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

8.4/10 Very Good! (1,204 reviews)

water is provided every day. pool is very big. mall right across from the hotel.

Reviewed on Jan 6, 2026

Playa Caracol Residences Vacation Rental

Save 100% on your flight

$1,099

per person

Feb 20 - Mar 1

found 19 hours ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

7.2/10 Good! (26 reviews)

Great, clean condo overlooking the pool and ocean. We didn't cook our meals, but used the restaurant on site. Staff was friendly and professional.

Reviewed on Dec 7, 2025

Find the Best Distrito Colón Vacation Packages

Distrito Colón Essential Information

Language	Spanish
Currency	Panamanian balboas
Local Welcome	¡Hola!
Local Goodbye	Adiós

Distrito Colón Hotel Deals

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama

Fully refundableReserve now, pay when you stay

$122 nightly

$135 total

Jan 18 - Jan 19

Total with taxes and fees

9/10 Wonderful! (4,808 reviews)

Nice room and accommodations

Reviewed on Jan 6, 2026

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama

Fully refundable

$110 nightly

$121 total

Jan 29 - Jan 30

Total with taxes and fees

8.4/10 Very Good! (2,371 reviews)

Love this hotel

Reviewed on Jan 5, 2026

Megapolis Hotel Panamá

Avenida Balboa Panama City

Fully refundableReserve now, pay when you stay

$217 nightly

$239 total

Jan 30 - Jan 31

Total with taxes and fees

8.4/10 Very Good! (1,351 reviews)

El hotel nos brindó una excelente atención.

Reviewed on Jan 4, 2026

See all 1,795 properties in Distrito Colón

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.